The network for 'metencephalon development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

metencephalon development

The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure.

NameDescriptionProbabilityFunc Analog Organism
Otx2orthodenticle homolog 2 (Drosophila)1.000
Pax2paired box gene 20.999
Shhsonic hedgehog0.999
En1engrailed 10.997
Gli2GLI-Kruppel family member GLI20.997
Fgf8fibroblast growth factor 80.995
Trp53transformation related protein 530.993
Gli3GLI-Kruppel family member GLI30.991
Emx1empty spiracles homolog 1 (Drosophila)0.991
Pitx2paired-like homeodomain transcription factor 20.988
Insm1insulinoma-associated 10.987
Fgfr1fibroblast growth factor receptor 10.987
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.982
Lmx1bLIM homeobox transcription factor 1 beta0.980
Ptenphosphatase and tensin homolog0.967
Pax6paired box gene 60.965
Phox2bpaired-like homeobox 2b0.946
Emx2empty spiracles homolog 2 (Drosophila)0.944
Tbx3T-box 30.937
Msx2homeobox, msh-like 20.931
Gbx2gastrulation brain homeobox 20.922
Hoxa1homeobox A10.919
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.915
Ascl1achaete-scute complex homolog 1 (Drosophila)0.913
Sox2SRY-box containing gene 20.907
Msx1homeobox, msh-like 10.898
Kiss1KiSS-1 metastasis-suppressor0.874
Neurog2neurogenin 20.873
Pax3paired box gene 30.872
Wnt6wingless-related MMTV integration site 60.868
Fgfr2fibroblast growth factor receptor 20.861
Smad4MAD homolog 4 (Drosophila)0.860
Eya1eyes absent 1 homolog (Drosophila)0.855
Wnt1wingless-related MMTV integration site 10.845
Ank1ankyrin 1, erythroid0.840
Abl1c-abl oncogene 1, non-receptor tyrosine kinase0.834
Hoxa2homeobox A20.832
Kcnj11potassium inwardly rectifying channel, subfamily J, member 110.828
Dkk1dickkopf homolog 1 (Xenopus laevis)0.812
Dlx5distal-less homeobox 50.810
Bdnfbrain derived neurotrophic factor0.806
Fzd8frizzled homolog 8 (Drosophila)0.792
Axin1axin 10.790
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.783
Lmx1aLIM homeobox transcription factor 1 alpha0.783
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.780
Smad3MAD homolog 3 (Drosophila)0.779
Dlg4discs, large homolog 4 (Drosophila)0.778
Gscgoosecoid homeobox0.770
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.758
Foxc1forkhead box C10.750
Gdnfglial cell line derived neurotrophic factor0.747
Gabrb3gamma-aminobutyric acid (GABA) A receptor, subunit beta 30.738
Wt1Wilms tumor 1 homolog0.735
Nr2f2nuclear receptor subfamily 2, group F, member 20.735
Prrx1paired related homeobox 10.733
Otx1orthodenticle homolog 1 (Drosophila)0.719
Tbx1T-box 10.715
Isl1ISL1 transcription factor, LIM/homeodomain0.711
Drd2dopamine receptor D20.709
Bmp4bone morphogenetic protein 40.705
Ctnnb1catenin (cadherin associated protein), beta 10.705
Lhx5LIM homeobox protein 50.701
Neurog3neurogenin 30.692
C1qccomplement component 1, q subcomponent, C chain0.691
Grid2glutamate receptor, ionotropic, delta 20.684
C1qacomplement component 1, q subcomponent, alpha polypeptide0.678
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.677
Gfra1glial cell line derived neurotrophic factor family receptor alpha 10.675
Rarbretinoic acid receptor, beta0.672
Bcl2B-cell leukemia/lymphoma 20.649
Nkx6-1NK6 homeobox 10.639
Tgfb2transforming growth factor, beta 20.637
Fgf10fibroblast growth factor 100.631
Foxp2forkhead box P20.630
Foxg1forkhead box G10.618
Bmp7bone morphogenetic protein 70.618
Nhlh1nescient helix loop helix 10.611
Fgf15fibroblast growth factor 150.604
Pbx1pre B-cell leukemia transcription factor 10.603
Kcnj6potassium inwardly-rectifying channel, subfamily J, member 60.601
Wnt3awingless-related MMTV integration site 3A0.593
Smosmoothened homolog (Drosophila)0.579
Rararetinoic acid receptor, alpha0.575
Lhx1LIM homeobox protein 10.574
Ntf3neurotrophin 30.573
Hoxd3homeobox D30.567
C1qbcomplement component 1, q subcomponent, beta polypeptide0.552
Sez6lseizure related 6 homolog like0.551
Apcadenomatosis polyposis coli0.541
Pou3f3POU domain, class 3, transcription factor 30.540
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.531
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.530
Ror1receptor tyrosine kinase-like orphan receptor 10.524
Pax8paired box gene 80.521
Rargretinoic acid receptor, gamma0.519
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
fgf3fibroblast growth factor 30.968
foxa2forkhead box A20.961
neurodneurogenic differentiation0.918
wnt1wingless-type MMTV integration site family, member 10.872
phox2apaired-like homeobox 2a0.857
pax6bpaired box gene 6b0.745
hnf1baHNF1 homeobox Ba0.648
wnt2wingless-type MMTV integration site family member 20.643
ascl1aachaete-scute complex-like 1a (Drosophila)0.616
her5hairy-related 50.551
hmx4H6 family homeobox 40.536
otpborthopedia homolog b0.508
egr2bearly growth response 2b0.507
mpzmyelin protein zero0.497
gbx1gastrulation brain homeobox 10.469
atoh1aatonal homolog 1a0.467
dkk1bdickkopf 1b0.453
wnt4awingless-type MMTV integration site family, member 4a0.440
wnt8bwingless-type MMTV integration site family, member 8b0.422
gbx2gastrulation brain homeo box 20.419
hoxb1bhomeo box B1b0.368
ptf1apancreas specific transcription factor, 1a0.347
lhx1aLIM homeobox 1a0.336
wnt10bwingless-type MMTV integration site family, member 10b0.323
gli1GLI-Kruppel family member 10.304
fzd3afrizzled homolog 3a0.295
fgf8afibroblast growth factor 8 a0.288
cdh2cadherin 2, neuronal0.287
tbx1T-box 10.276
dbx1adeveloping brain homeobox 1a0.267
ntlano tail a0.245
ndr2nodal-related 20.242
hoxc4ahomeo box C4a0.242
eng2aengrailed 2a0.239
otx1borthodenticle homolog 1b0.231
col4a5collagen, type IV, alpha 5 (Alport syndrome)0.228
shhasonic hedgehog a0.220
tbx16T-box gene 160.209
nadl1.1neural adhesion molecule L1.10.208
sox2SRY-box containing gene 20.207
dlx2adistal-less homeobox gene 2a0.202
spry2sprouty homolog 20.198
admpanti-dorsalizing morphogenic protein0.195
lfnglunatic fringe homolog0.192
neurod4neurogenic differentiation 40.179
sp5lSp5 transcription factor-like0.177
nanos3nanos homolog 30.172
sox32SRY-box containing gene 320.162
pax8paired box gene 80.158
zfyve26zinc finger, FYVE domain containing 260.157
zic2azic family member 2 (odd-paired homolog, Drosophila), a0.153
neurog1neurogenin 10.153
hoxb1ahomeo box B1a0.150
pitx3paired-like homeodomain transcription factor 30.147
hoxd4ahomeo box D4a0.146
irx7iroquois homeobox protein 70.141
tal1T-cell acute lymphocytic leukemia 10.140
map2k4amitogen-activated protein kinase kinase 4a0.140
wnt3wingless-type MMTV integration site family, member 30.134
sox17SRY-box containing gene 170.133
eng2bengrailed 2b0.131
cyp26c1cytochrome P450, family 26, subfamily C, polypeptide 10.129
wif1wnt inhibitory factor 10.126
wnt11wingless-type MMTV integration site family, member 110.124
zic3zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)0.123
st8sia2ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 20.120
cdx4caudal type homeo box transcription factor 40.119
gata2aGATA-binding protein 2a0.118
her8ahairy-related 8a0.118
foxa1forkhead box A10.113
nkx6.2NK6 transcription factor related, locus 20.110
six3bsine oculis homeobox homolog 3b0.102
meis3myeloid ecotropic viral integration site 30.102
raraaretinoic acid receptor, alpha a0.101
fbp1bfructose-1,6-bisphosphatase 1b0.097
wnt10awingless-type MMTV integration site family, member 10a0.096
hmx3homeo box (H6 family) 30.096
pou5f1POU domain, class 5, transcription factor 10.092
mnx1motor neuron and pancreas homeobox 10.092
mllmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.092
flhfloating head0.091
nkx2.2aNK2 transcription factor related 2a0.091
lratblecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)0.091
sox19bSRY-box containing gene 19b0.091
cx30.3connexin 30.30.089
irx3airoquois homeobox protein 3a0.087
fgf10afibroblast growth factor 10a0.087
olig4oligodendrocyte transcription factor 40.086
gja3gap junction protein, alpha 30.085
bmp2abone morphogenetic protein 2a0.085
igf1rbinsulin-like growth factor 1b receptor0.085
dab1bdisabled homolog 1b (Drosophila)0.083
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
HDAC2histone deacetylase 20.975
BCL2L1BCL2-like 10.965
ESR1estrogen receptor 10.963
TRRAPtransformation/transcription domain-associated protein0.912
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.901
NR0B1nuclear receptor subfamily 0, group B, member 10.849
PDZD11PDZ domain containing 110.834
TP53tumor protein p530.833
PPP5Cprotein phosphatase 5, catalytic subunit0.736
SKIv-ski sarcoma viral oncogene homolog (avian)0.535
ASNSasparagine synthetase (glutamine-hydrolyzing)0.497
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.485
SNTG2syntrophin, gamma 20.477
CHDHcholine dehydrogenase0.476
ARandrogen receptor0.472
LMO4LIM domain only 40.415
MDM2Mdm2 p53 binding protein homolog (mouse)0.413
COPB1coatomer protein complex, subunit beta 10.410
ATG13ATG13 autophagy related 13 homolog (S. cerevisiae)0.403
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.400
APCadenomatous polyposis coli0.391
MYOD1myogenic differentiation 10.372
PPFIA1protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 10.348
PTCH1patched 10.346
NRXN1neurexin 10.331
NCOA1nuclear receptor coactivator 10.316
HNF4Ahepatocyte nuclear factor 4, alpha0.312
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 20.312
SETD8SET domain containing (lysine methyltransferase) 80.304
PDX1pancreatic and duodenal homeobox 10.301
GATA2GATA binding protein 20.299
HOXD12homeobox D120.285
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.282
MAFAv-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)0.276
SOX1SRY (sex determining region Y)-box 10.260
COPB2coatomer protein complex, subunit beta 2 (beta prime)0.253
NDPNorrie disease (pseudoglioma)0.245
ZNF512Bzinc finger protein 512B0.236
SESN2sestrin 20.234
HOXA9homeobox A90.227
TCF4transcription factor 40.224
TCF12transcription factor 120.218
RIN1Ras and Rab interactor 10.212
ACTL6Bactin-like 6B0.211
FGF3fibroblast growth factor 30.207
EGFRepidermal growth factor receptor0.202
ATN1atrophin 10.197
MYO16myosin XVI0.187
NTRK3neurotrophic tyrosine kinase, receptor, type 30.186
RAXretina and anterior neural fold homeobox0.181
RUNX1runt-related transcription factor 10.181
PHLPP1PH domain and leucine rich repeat protein phosphatase 10.177
UBR1ubiquitin protein ligase E3 component n-recognin 10.174
CALCAcalcitonin-related polypeptide alpha0.172
SIX6SIX homeobox 60.166
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.166
PIK3R3phosphoinositide-3-kinase, regulatory subunit 3 (gamma)0.166
DNMT3ADNA (cytosine-5-)-methyltransferase 3 alpha0.160
RPL18Aribosomal protein L18a0.157
AMBRA1autophagy/beclin-1 regulator 10.150
SEC24DSEC24 family, member D (S. cerevisiae)0.150
TMED10transmembrane emp24-like trafficking protein 10 (yeast)0.148
SEC61A1Sec61 alpha 1 subunit (S. cerevisiae)0.147
DDX17DEAD (Asp-Glu-Ala-Asp) box polypeptide 170.147
NCOR1nuclear receptor corepressor 10.141
TRIP6thyroid hormone receptor interactor 60.139
TADA2Atranscriptional adaptor 2A0.138
TAL1T-cell acute lymphocytic leukemia 10.138
MPDZmultiple PDZ domain protein0.138
LSAMPlimbic system-associated membrane protein0.137
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.137
BAI1brain-specific angiogenesis inhibitor 10.136
GATA4GATA binding protein 40.135
METmet proto-oncogene (hepatocyte growth factor receptor)0.134
PBX1pre-B-cell leukemia homeobox 10.131
LPHN1latrophilin 10.128
USP7ubiquitin specific peptidase 7 (herpes virus-associated)0.127
SHC3SHC (Src homology 2 domain containing) transforming protein 30.124
WNT3Awingless-type MMTV integration site family, member 3A0.124
FEZ1fasciculation and elongation protein zeta 1 (zygin I)0.124
NEGR1neuronal growth regulator 10.121
POU4F3POU class 4 homeobox 30.121
DLG2discs, large homolog 2 (Drosophila)0.121
SEC23ASec23 homolog A (S. cerevisiae)0.120
KCNQ2potassium voltage-gated channel, KQT-like subfamily, member 20.118
LHX3LIM homeobox 30.118
SETDB1SET domain, bifurcated 10.117
SEC24ASEC24 family, member A (S. cerevisiae)0.116
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit0.113
LRRK2leucine-rich repeat kinase 20.113
NKX6-1NK6 homeobox 10.113
DKK1dickkopf homolog 1 (Xenopus laevis)0.111
TP73tumor protein p730.111
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.110
SOX11SRY (sex determining region Y)-box 110.110
ARHGAP22Rho GTPase activating protein 220.106
FOXA2forkhead box A20.105
SRRM4serine/arginine repetitive matrix 40.105
HYOU1hypoxia up-regulated 10.105
CHD3chromodomain helicase DNA binding protein 30.105
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism