The network for 'response to heparin' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to heparin

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus.

NameDescriptionProbabilityFunc Analog Organism
Fgfr2fibroblast growth factor receptor 20.838
Isl1ISL1 transcription factor, LIM/homeodomain0.832
Jag1jagged 10.703
Meox2mesenchyme homeobox 20.672
Gli3GLI-Kruppel family member GLI30.654
Robo1roundabout homolog 1 (Drosophila)0.557
Sox4SRY-box containing gene 40.536
Pax3paired box gene 30.412
Nf1neurofibromatosis 10.391
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.383
Sfrp2secreted frizzled-related protein 20.370
Ednrbendothelin receptor type B0.321
Sox11SRY-box containing gene 110.254
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.252
Bmp4bone morphogenetic protein 40.227
Kdrkinase insert domain protein receptor0.206
FosFBJ osteosarcoma oncogene0.188
Tcfap2atranscription factor AP-2, alpha0.174
Shesrc homology 2 domain-containing transforming protein E0.173
Apcadenomatosis polyposis coli0.169
Prrx1paired related homeobox 10.166
Hand1heart and neural crest derivatives expressed transcript 10.159
Ctnnb1catenin (cadherin associated protein), beta 10.149
Efnb2ephrin B20.146
Tgfb2transforming growth factor, beta 20.144
Egr2early growth response 20.131
Fgfr3fibroblast growth factor receptor 30.120
Sox17SRY-box containing gene 170.116
Pax6paired box gene 60.110
Ptprbprotein tyrosine phosphatase, receptor type, B0.108
Ntf3neurotrophin 30.100
Kitkit oncogene0.089
Fgf8fibroblast growth factor 80.088
Emx1empty spiracles homolog 1 (Drosophila)0.085
Sall3sal-like 3 (Drosophila)0.082
Ptpn11protein tyrosine phosphatase, non-receptor type 110.082
Hif1ahypoxia inducible factor 1, alpha subunit0.080
Ednraendothelin receptor type A0.079
Sox9SRY-box containing gene 90.077
Hey2hairy/enhancer-of-split related with YRPW motif 20.077
Ptch1patched homolog 10.074
Hes1hairy and enhancer of split 1 (Drosophila)0.074
Vegfavascular endothelial growth factor A0.070
Foxc2forkhead box C20.063
Trp53transformation related protein 530.062
Aplnrapelin receptor0.061
Meox1mesenchyme homeobox 10.061
Zeb1zinc finger E-box binding homeobox 10.059
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.058
Hhexhematopoietically expressed homeobox0.058
Col2a1collagen, type II, alpha 10.056
Fgf10fibroblast growth factor 100.053
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.053
Ror2receptor tyrosine kinase-like orphan receptor 20.052
Eya1eyes absent 1 homolog (Drosophila)0.050
Nos3nitric oxide synthase 3, endothelial cell0.050
Ptgs2prostaglandin-endoperoxide synthase 20.048
Pitx2paired-like homeodomain transcription factor 20.047
Sox2SRY-box containing gene 20.046
Shhsonic hedgehog0.046
Bmpr1abone morphogenetic protein receptor, type 1A0.044
Ldb2LIM domain binding 20.044
Cldn5claudin 50.043
Kitlkit ligand0.042
Gata4GATA binding protein 40.041
Npr3natriuretic peptide receptor 30.041
Sox18SRY-box containing gene 180.040
Wnt5awingless-related MMTV integration site 5A0.040
Itgb1integrin beta 1 (fibronectin receptor beta)0.039
JunJun oncogene0.039
Chd7chromodomain helicase DNA binding protein 70.037
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.037
Rb1retinoblastoma 10.037
Bmp5bone morphogenetic protein 50.036
Tekendothelial-specific receptor tyrosine kinase0.036
Slit3slit homolog 3 (Drosophila)0.034
Notch3Notch gene homolog 3 (Drosophila)0.033
Cdh11cadherin 110.033
Tmeff2transmembrane protein with EGF-like and two follistatin-like domains 20.033
Pbx1pre B-cell leukemia transcription factor 10.032
Fgf3fibroblast growth factor 30.032
Otx2orthodenticle homolog 2 (Drosophila)0.032
Rarbretinoic acid receptor, beta0.031
Bcl6bB-cell CLL/lymphoma 6, member B0.031
Tie1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.031
Foxc1forkhead box C10.030
Six4sine oculis-related homeobox 4 homolog (Drosophila)0.029
Robo2roundabout homolog 2 (Drosophila)0.028
Gja4gap junction protein, alpha 40.028
Icam2intercellular adhesion molecule 20.027
Tshz3teashirt zinc finger family member 30.027
Gli2GLI-Kruppel family member GLI20.027
Gas1growth arrest specific 10.027
Smosmoothened homolog (Drosophila)0.026
Hes5hairy and enhancer of split 5 (Drosophila)0.026
Cxcl12chemokine (C-X-C motif) ligand 120.025
BmperBMP-binding endothelial regulator0.025
Phox2bpaired-like homeobox 2b0.025
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
FOSFBJ murine osteosarcoma viral oncogene homolog0.352
IER2immediate early response 20.284
ZFP36zinc finger protein 36, C3H type, homolog (mouse)0.272
EGR3early growth response 30.192
NR4A2nuclear receptor subfamily 4, group A, member 20.083
FOSBFBJ murine osteosarcoma viral oncogene homolog B0.067
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.061
EGR2early growth response 20.053
JUNBjun B proto-oncogene0.053
JUNjun proto-oncogene0.053
SNAI1snail homolog 1 (Drosophila)0.036
NR4A1nuclear receptor subfamily 4, group A, member 10.020
CEBPBCCAAT/enhancer binding protein (C/EBP), beta0.019
DUSP1dual specificity phosphatase 10.015
ATF3activating transcription factor 30.014
ID4inhibitor of DNA binding 4, dominant negative helix-loop-helix protein0.012
ATN1atrophin 10.012
SFRP4secreted frizzled-related protein 40.011
FBLN1fibulin 10.011
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Junbjun B proto-oncogene0.726
FosFBJ osteosarcoma oncogene0.464
Egr2early growth response 20.182
Nr4a1nuclear receptor subfamily 4, group A, member 10.173
Egr1early growth response 10.135
Ier2immediate early response 20.105
Btg2BTG family, member 20.079
Cyr61cysteine-rich, angiogenic inducer, 610.037
Nr4a3nuclear receptor subfamily 4, group A, member 30.027
Dusp1dual specificity phosphatase 10.024
Dusp6dual specificity phosphatase 60.020
Zfp36zinc finger protein 360.013
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism