The network for 'protein complex biogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

protein complex biogenesis

A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a protein complex. Includes the synthesis of the constituent protein molecules, and those protein modifications that are involved in synthesis or assembly of the complex.

NameDescriptionProbabilityFunc Analog Organism
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
cysl-1Protein CYSL-10.329
klp-7Protein KLP-70.307
twk-18Protein TWK-180.279
rpt-5Protein RPT-50.275
act-4Protein ACT-40.257
tag-232Protein TAG-2320.251
atn-1Protein ATN-10.244
unc-68Protein UNC-680.230
dnc-2Protein DNC-20.229
unc-15Protein UNC-150.219
ubc-12Protein UBC-120.215
unc-60Protein UNC-600.211
lmn-1Protein LMN-10.209
spc-1Protein SPC-10.202
his-1Protein HIS-10.197
R11A8.7Protein R11A8.70.196
R90.1Protein R90.10.195
kle-2Protein KLE-20.190
eat-6Protein EAT-60.185
egl-44Protein EGL-440.184
his-64Protein HIS-640.184
sas-6Protein SAS-60.180
egl-30Protein EGL-300.180
D1044.2Protein D1044.20.174
pqn-59Protein PQN-590.170
gdi-1Protein GDI-10.169
T12G3.4Protein T12G3.40.168
zyg-9Protein ZYG-90.167
plp-1Protein PLP-10.163
ZC395.10Protein ZC395.100.160
R148.3Protein R148.30.158
F39G3.5Protein F39G3.50.158
cas-2Protein CAS-20.157
CELE_Y51A2D.14Protein Y51A2D.140.156
rpn-8Protein RPN-80.156
F14B8.6Protein F14B8.60.155
mig-5Protein MIG-50.153
lig-1Protein LIG-10.151
deb-1Protein DEB-10.150
D1081.8Protein D1081.80.149
CELE_W02D7.5Protein W02D7.50.142
bath-42Protein BATH-420.137
klp-18Protein KLP-180.137
ced-4Protein CED-40.137
pkg-1Protein PKG-10.136
mat-3Protein MAT-30.134
csn-5Protein CSN-50.133
sas-4Protein SAS-40.133
Y106G6A.1Protein Y106G6A.10.130
ace-2Protein ACE-20.130
lin-36Protein LIN-360.130
mrt-2Protein MRT-20.128
vab-3Protein VAB-30.128
tag-241Protein TAG-2410.128
spdl-1Protein SPDL-10.128
nmy-2Protein NMY-20.126
sas-5Protein SAS-50.124
dpf-3Protein DPF-30.124
klp-19Protein KLP-190.123
C56G2.7Protein C56G2.70.122
Y110A7A.9Protein Y110A7A.90.122
kin-3Protein KIN-30.122
sqt-1Protein SQT-10.121
his-5Protein HIS-50.120
ajm-1Protein AJM-10.120
aspm-1Protein ASPM-10.120
mcm-7Protein MCM-70.119
act-2Protein ACT-20.119
ifc-1Protein IFC-10.118
egl-19Protein EGL-190.117
tpa-1Protein TPA-10.116
unc-112Protein UNC-1120.116
cdc-42Protein CDC-420.115
nlg-1Protein NLG-10.113
npl-4.2Protein NPL-4.20.113
CELE_C17H12.13Protein C17H12.130.112
vbh-1Protein VBH-10.112
CELE_C24H12.5Protein C24H12.50.111
scc-1Protein SCC-10.111
B0336.3Protein B0336.30.110
pas-4Protein PAS-40.110
cct-1Protein CCT-10.110
CELE_ZK795.3Protein ZK795.30.109
rnr-1Protein RNR-10.109
madd-4Protein MADD-40.109
gst-7Protein GST-70.108
Y48G1C.7Protein Y48G1C.70.108
cls-2Protein CLS-20.108
C16A11.4Protein C16A11.40.108
F11D5.1Protein F11D5.10.107
uba-1Protein UBA-10.107
inx-15Protein INX-150.107
dep-1Protein DEP-10.106
vha-9Protein VHA-90.105
tbc-2Protein TBC-20.104
hsr-9Protein HSR-90.104
mpk-1Protein MPK-10.103
T05G5.1Protein T05G5.10.103
CELE_C39E9.12Protein C39E9.120.103
otub-1Protein OTUB-10.102
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
chdchordin0.580
tp53tumor protein p530.371
psmd12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.233
bambiaBMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a0.221
nsfaN-ethylmaleimide-sensitive factor a0.189
lama4laminin, alpha 40.182
myhz1.1myosin, heavy polypeptide 1.1, skeletal muscle0.181
tjp1tight junction protein 1 (zona occludens 1)0.180
myogmyogenin0.175
ccm2cerebral cavernous malformation 20.173
sod1superoxide dismutase 1, soluble0.173
rpa1replication protein A10.166
insm1ainsulinoma-associated 1a0.166
psma4proteasome (prosome, macropain) subunit, alpha type, 40.147
hsp90a.1heat shock protein 90-alpha 10.145
hspa4aheat shock protein 4a0.143
arpc5aactin related protein 2/3 complex, subunit 5A0.137
msnamoesin a0.135
fn1fibronectin 10.135
wnt10awingless-type MMTV integration site family, member 10a0.134
vwfvon Willebrand factor0.134
isl2aislet2a0.130
psma8proteasome (prosome, macropain) subunit, alpha type, 80.128
atp6v0cbATPase, H+ transporting, lysosomal, V0 subunit c, b0.126
mef2dmyocyte enhancer factor 2d0.125
gli1GLI-Kruppel family member 10.118
zgc:100838zgc:1008380.117
tnnt3btroponin T3b, skeletal, fast0.116
hsp90a.2heat shock protein 90-alpha 20.115
pafah1b1bplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b0.112
smad9MAD homolog 9 (Drosophila)0.110
dpysl3dihydropyrimidinase-like 30.107
gpiaglucose phosphate isomerase a0.107
gng3guanine nucleotide binding protein (G protein), gamma 30.105
ptch2patched 20.105
vmhcventricular myosin heavy chain0.104
atp1a3aATPase, Na+/K+ transporting, alpha 3a polypeptide0.103
mstnbmyostatin b0.102
mef2cbmyocyte enhancer factor 2cb0.102
tal1T-cell acute lymphocytic leukemia 10.101
foxo3bforkhead box O3b0.100
tll1tolloid-like 10.098
dync1h1dynein, cytoplasmic 1, heavy chain 10.097
bcl2l10BCL2-like 10 (apoptosis facilitator)0.097
tie1endothelium-specific receptor tyrosine kinase 10.096
smyd2bSET and MYND domain containing 2b0.096
aldocbaldolase C, fructose-bisphosphate, b0.095
fabp3fatty acid binding protein 3, muscle and heart0.094
mllt11myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 110.094
nusap1nucleolar and spindle associated protein 10.091
rap1bRAS related protein 1b0.087
aldh1a2aldehyde dehydrogenase 1 family, member A20.085
wt1bwilms tumor 1b0.085
dlg2discs, large (Drosophila) homolog 20.084
tnni2a.4troponin I, skeletal, fast 2a.40.082
foxh1forkhead box H10.077
pkd2polycystic kidney disease 20.076
cct5chaperonin containing TCP1, subunit 5 (epsilon)0.076
atp1a3bATPase, Na+/K+ transporting, alpha 3b polypeptide0.075
myl9lmyosin, light polypeptide 9, like0.075
pbx4pre-B-cell leukemia transcription factor 40.074
puf60bpoly-U binding splicing factor b0.073
dpysl5adihydropyrimidinase-like 5a0.073
sgcdsarcoglycan, delta (dystrophin-associated glycoprotein)0.072
pds5bPDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)0.072
bmp7bbone morphogenetic protein 7b0.070
fli1bfriend leukemia integration 1b0.070
tbeta-abeta thymosin-like protein 20.070
col1a1bcollagen, type I, alpha 1b0.069
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.069
psmb4proteasome (prosome, macropain) subunit, beta type, 40.068
ptch1patched 10.068
per3period homolog 3 (Drosophila)0.067
s100a10bS100 calcium binding protein A10b0.067
crabp2acellular retinoic acid binding protein 2, a0.067
cotl1coactosin-like 1 (Dictyostelium)0.066
alas2aminolevulinate, delta-, synthetase 20.066
furinafurin (paired basic amino acid cleaving enzyme) a0.066
mcm7MCM7 minichromosome maintenance deficient 7 (S. cerevisiae)0.066
nap1l1nucleosome assembly protein 1, like 10.066
arpc1bactin related protein 2/3 complex, subunit 1B0.065
cntn1acontactin 1a0.065
tpm1tropomyosin 1 (alpha)0.065
col18a1collagen type XVIII, alpha 10.064
desmadesmin a0.064
mapk3mitogen-activated protein kinase 30.064
myf6myogenic factor 60.064
alcambactivated leukocyte cell adhesion molecule b0.064
ret1receptor tyrosine kinase0.064
psmb3proteasome (prosome, macropain) subunit, beta type, 30.062
smyd1bSET and MYND domain containing 1b0.062
sox32SRY-box containing gene 320.060
atp1b3bATPase, Na+/K+ transporting, beta 3b polypeptide0.060
nrg2aneuregulin 2a0.059
bmp4bone morphogenetic protein 40.059
flot1flotillin 10.059
nmnat2nicotinamide nucleotide adenylyltransferase 20.058
cdh2cadherin 2, neuronal0.058
pink1PTEN induced putative kinase 10.058
mdm2transformed 3T3 cell double minute 2 homolog (mouse)0.057
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
armarmadillo0.979
gemininCG3183 gene product from transcript CG3183-RA0.967
MadMothers against dpp0.943
Cp190Centrosomal protein 190kD0.929
mbcmyoblast city0.918
ncdnon-claret disjunctional0.905
Cdc37CG12019 gene product from transcript CG12019-RA0.900
MoeMoesin0.898
eIF-4EEukaryotic initiation factor 4E0.886
tkvthickveins0.879
stgstring0.848
cpbcapping protein beta0.831
CycBCyclin B0.826
WASpCG1520 gene product from transcript CG1520-RA0.823
CctgammaCG8977 gene product from transcript CG8977-RC0.820
Arp66BActin-related protein 66B0.789
Grip71CG10346 gene product from transcript CG10346-RA0.786
Pros26.4Proteasome 26S subunit subunit 4 ATPase0.785
CycECyclin E0.781
wupAwings up A0.776
Rab11Rab-protein 110.769
MerMerlin0.768
chicchickadee0.758
Rpt1CG1341 gene product from transcript CG1341-RA0.751
CG7033CG7033 gene product from transcript CG7033-RC0.736
Arc-p34CG10954 gene product from transcript CG10954-RA0.710
Zasp66Z band alternatively spliced PDZ-motif protein 660.708
shotshort stop0.682
smt3CG4494 gene product from transcript CG4494-RA0.680
tsrtwinstar0.665
hydhyperplastic discs0.650
BRWD3CG31132 gene product from transcript CG31132-RA0.638
E(spl)Enhancer of split0.636
CycACyclin A0.622
cpacapping protein alpha0.608
Vrp1Verprolin 10.606
cazcabeza0.601
CG4680CG4680 gene product from transcript CG4680-RA0.600
Dcr-2Dicer-20.599
cmetCENP-meta0.593
Pros45CG1489 gene product from transcript CG1489-RA0.583
RhoGEF2CG9635 gene product from transcript CG9635-RF0.577
slssallimus0.554
HmgDHigh mobility group protein D0.550
giggigas0.546
eglegalitarian0.537
chicoCG5686 gene product from transcript CG5686-RB0.530
gammaTub37Cgamma-Tubulin at 37C0.527
benbendless0.526
Grip84gamma-tubulin ring protein 840.523
Tcp-1etaCG8351 gene product from transcript CG8351-RA0.516
upupheld0.510
SosSon of sevenless0.509
CG9772CG9772 gene product from transcript CG9772-RB0.499
par-6CG5884 gene product from transcript CG5884-RA0.496
twetwine0.493
Klp10ACG1453 gene product from transcript CG1453-RA0.486
MicalMolecule interacting with CasL0.486
Sgt1CG9617 gene product from transcript CG9617-RA0.470
idaimaginal discs arrested0.466
Rab5Rab-protein 50.465
Pp2A-29BProtein phosphatase 2A at 29B0.463
IncenpInner centromere protein0.456
14-3-3zetaCG17870 gene product from transcript CG17870-RB0.455
CG10267CG10267 gene product from transcript CG10267-RB0.451
CycB3Cyclin B30.449
CG5525CG5525 gene product from transcript CG5525-RA0.449
Vps35Vacuolar protein sorting 350.441
Or46aOdorant receptor 46a0.438
Rpt3CG16916 gene product from transcript CG16916-RA0.438
RbfRetinoblastoma-family protein0.435
scrascraps0.431
wacwee Augmin0.422
Su(H)Suppressor of Hairless0.409
EphrinCG1862 gene product from transcript CG1862-RA0.406
marsCG17064 gene product from transcript CG17064-RB0.404
Npc1aNiemann-Pick type C-1a0.393
G-oalpha47AG protein oalpha 47A0.378
tefutelomere fusion0.377
JIL-1CG6297 gene product from transcript CG6297-RA0.372
CG31224CG31224 gene product from transcript CG31224-RA0.369
bifbifocal0.365
seiseizure0.365
aspabnormal spindle0.356
ctaconcertina0.354
vig2CG11844 gene product from transcript CG11844-RB0.352
Pink1PTEN-induced putative kinase 10.346
Akt1CG4006 gene product from transcript CG4006-RA0.346
Rac1CG2248 gene product from transcript CG2248-RA0.344
HLHm7E(spl) region transcript m70.336
Spc105RSpc105-related0.334
Grip128CG9201 gene product from transcript CG9201-RB0.331
CSN5COP9 complex homolog subunit 50.327
Arp87CActin-related protein 87C0.318
HLHmdeltaE(spl) region transcript mdelta0.318
Cdc42CG12530 gene product from transcript CG12530-RA0.317
tacctransforming acidic coiled-coil protein0.313
ToporsTopoisomerase I-interacting protein0.308
SmoxSmad on X0.306
Dhc64CDynein heavy chain 64C0.306
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.758
Hspd1heat shock protein 1 (chaperonin)0.739
Acadlacyl-Coenzyme A dehydrogenase, long-chain0.653
Gng7guanine nucleotide binding protein (G protein), gamma 70.629
LOC24906RoBo-10.588
Myo1bmyosin Ib0.581
Mapre1microtubule-associated protein, RP/EB family, member 10.580
Jak2Janus kinase 20.580
Map1amicrotubule-associated protein 1A0.563
Gnao1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O0.532
Hbbhemoglobin, beta0.515
Jak1Janus kinase 10.513
Actr3ARP3 actin-related protein 3 homolog (yeast)0.510
Leprleptin receptor0.505
S1pr2sphingosine-1-phosphate receptor 20.495
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.492
Trim23tripartite motif-containing 230.491
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.469
Pfn1profilin 10.440
Grin2bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.431
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.426
Avpr1barginine vasopressin receptor 1B0.421
RT1-Db1RT1 class II, locus Db10.418
Cct4chaperonin containing Tcp1, subunit 4 (delta)0.417
Alas2aminolevulinate, delta-, synthase 20.415
Litaflipopolysaccharide-induced TNF factor0.406
S100a10S100 calcium binding protein A100.404
Snap25synaptosomal-associated protein 250.403
Mmp7matrix metallopeptidase 70.398
RT1-BaRT1 class II, locus Ba0.398
Col3a1collagen, type III, alpha 10.383
Ntrk3neurotrophic tyrosine kinase, receptor, type 30.383
Efhd2EF-hand domain family, member D20.379
Aqp4aquaporin 40.375
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.371
Psmc1proteasome (prosome, macropain) 26S subunit, ATPase, 10.364
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.360
Apba1amyloid beta (A4) precursor protein-binding, family A, member 10.355
Rhoaras homolog gene family, member A0.355
Neflneurofilament, light polypeptide0.351
Slc22a1solute carrier family 22 (organic cation transporter), member 10.350
Metmet proto-oncogene0.348
Apba3amyloid beta (A4) precursor protein-binding, family A, member 30.348
St13suppression of tumorigenicity 130.348
Grin1glutamate receptor, ionotropic, N-methyl D-aspartate 10.342
Tpm3tropomyosin 3, gamma0.341
Il24interleukin 240.330
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.325
Syt11synaptotagmin XI0.318
Taok1TAO kinase 10.314
Hrh2histamine receptor H 20.314
Lims1LIM and senescent cell antigen-like domains 10.314
Hbb-b1hemoglobin, beta adult major chain0.313
Myo1cmyosin IC0.313
Camk2bcalcium/calmodulin-dependent protein kinase II beta0.312
Cdc37cell division cycle 37 homolog (S. cerevisiae)0.310
Kcnab1potassium voltage-gated channel, shaker-related subfamily, beta member 10.307
Stxbp1syntaxin binding protein 10.307
LOC100134871beta globin minor gene0.306
Igfalsinsulin-like growth factor binding protein, acid labile subunit0.305
Rin1Ras and Rab interactor 10.300
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.297
Ccl2chemokine (C-C motif) ligand 20.296
Hba-a2hemoglobin alpha, adult chain 20.293
Arpc1bactin related protein 2/3 complex, subunit 1B0.291
Map2k1mitogen activated protein kinase kinase 10.290
Mylk2myosin light chain kinase 20.289
Ripk3receptor-interacting serine-threonine kinase 30.289
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A, alpha isoform0.286
Cx3cl1chemokine (C-X3-C motif) ligand 10.282
Castcalpastatin0.279
Iqgap1IQ motif containing GTPase activating protein 10.276
Dlgap1discs, large (Drosophila) homolog-associated protein 10.276
Cplx1complexin 10.275
Cd46CD46 molecule, complement regulatory protein0.273
Cd47Cd47 molecule0.269
Impg2interphotoreceptor matrix proteoglycan 20.269
Acacbacetyl-Coenzyme A carboxylase beta0.268
Lbrlamin B receptor0.267
Prkcbprotein kinase C, beta0.264
Bmp7bone morphogenetic protein 70.262
Cttncortactin0.262
Hbp1HMG-box transcription factor 10.260
Acadvlacyl-Coenzyme A dehydrogenase, very long chain0.260
Hsd3b5hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 50.259
Ctsccathepsin C0.259
Actc1actin, alpha, cardiac muscle 10.258
Akr1d1aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)0.258
Map2microtubule-associated protein 20.258
Map3k9mitogen-activated protein kinase kinase kinase 90.257
Mybphmyosin binding protein H0.256
Pak2p21 protein (Cdc42/Rac)-activated kinase 20.255
HrasHarvey rat sarcoma virus oncogene0.254
Anxa2annexin A20.254
Olfm1olfactomedin 10.254
Map2k2mitogen activated protein kinase kinase 20.252
Vamp1vesicle-associated membrane protein 10.251
Nap1l1nucleosome assembly protein 1-like 10.248
Ezrezrin0.247
Arpc2actin related protein 2/3 complex, subunit 20.247
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
HHT1Hht1p0.982
HHF1Hhf1p0.963
SNF1Snf1p0.948
CDC12Cdc12p0.948
CDC11Cdc11p0.945
RPT3Rpt3p0.930
RPT2Rpt2p0.916
VRP1Vrp1p0.914
PFD1Pfd1p0.908
ASK1Ask1p0.907
GIM5Gim5p0.907
RPT6Rpt6p0.883
HSP82Hsp82p0.873
SAK1Sak1p0.866
CDC28Cdc28p0.866
CCT3Cct3p0.866
PRE1Pre1p0.864
DYN1Dyn1p0.857
MDM35Mdm35p0.843
SLA1Sla1p0.842
KCC4Kcc4p0.839
RAD53Rad53p0.832
PET191Pet191p0.829
GIN4Gin4p0.812
SLA2Sla2p0.811
ASF1Asf1p0.808
HIR2Hir2p0.808
NUF2Nuf2p0.806
CIN1Cin1p0.803
STE4Ste4p0.792
MYO5Myo5p0.772
BBC1Bbc1p0.758
RTT106Rtt106p0.756
CDC3Cdc3p0.752
DAD2Dad2p0.750
ARC40Arc40p0.738
DIA2Dia2p0.718
ECM29Ecm29p0.713
MDM10Mdm10p0.711
VMA7Vma7p0.710
SHS1Shs1p0.708
BDF1Bdf1p0.706
CDC20Cdc20p0.704
SSC1Ssc1p0.697
DAM1Dam1p0.694
RPT4Rpt4p0.693
SPC24Spc24p0.684
ARP3Arp3p0.666
MRPL25Mrpl25p0.665
HIF1Hif1p0.665
DAD4Dad4p0.664
ACK1Ack1p0.655
SHY1Shy1p0.651
AHA1Aha1p0.645
RPN6Rpn6p0.632
VMA1Vma1p0.628
RLF2Rlf2p0.625
IMP1Imp1p0.621
SEC24Sec24p0.621
SPC34Spc34p0.616
RPN2Rpn2p0.606
SPC29Spc29p0.606
HTA1Hta1p0.602
BBP1Bbp1p0.600
PEP3Pep3p0.596
CHD1Chd1p0.591
CMC1Cmc1p0.590
YKE2Yke2p0.587
VMA6Vma6p0.586
CDC37Cdc37p0.585
SYP1Syp1p0.584
RPN14Rpn14p0.582
RPN1Rpn1p0.577
HIR1Hir1p0.575
CLB3Clb3p0.573
HSP78Hsp78p0.570
SCO1Sco1p0.568
SPC19Spc19p0.563
SAM37Sam37p0.561
SEC23Sec23p0.551
SPT16Spt16p0.550
HHF2Hhf2p0.544
COX7Cox7p0.543
MPS1Mps1p0.538
KTI11Kti11p0.536
PEP5Pep5p0.535
HSM3Hsm3p0.533
PET100Pet100p0.529
TID3Tid3p0.526
KIN2Kin2p0.521
ARC15Arc15p0.519
ACN9Acn9p0.517
MDS3Mds3p0.510
HSK3Hsk3p0.509
TRA1Tra1p0.508
KAR9Kar9p0.508
ATP12Atp12p0.507
SEM1Sem1p0.506
CBF2Cbf2p0.506
ABP1Abp1p0.499