The network for 'negative regulation of interferon gamma biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of interferon gamma biosynthetic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-gamma.

NameDescriptionProbabilityFunc Analog Organism
Cd80CD80 antigen0.222
Ifnginterferon gamma0.192
Foxn1forkhead box N10.134
Gli2GLI-Kruppel family member GLI20.055
Rag2recombination activating gene 20.042
Ikzf1IKAROS family zinc finger 10.037
Il4interleukin 40.035
Rag1recombination activating gene 10.028
Foxp1forkhead box P10.027
Pdcd1programmed cell death 10.027
Foxp2forkhead box P20.025
TcraT-cell receptor alpha chain0.024
Cd28CD28 antigen0.023
Cd19CD19 antigen0.023
Card11caspase recruitment domain family, member 110.023
Il10interleukin 100.020
Naip6NLR family, apoptosis inhibitory protein 60.018
Il2interleukin 20.018
FasFas (TNF receptor superfamily member 6)0.017
Map3k14mitogen-activated protein kinase kinase kinase 140.017
Slamf1signaling lymphocytic activation molecule family member 10.017
Rc3h1RING CCCH (C3H) domains 10.017
Tnfrsf9tumor necrosis factor receptor superfamily, member 90.016
Ttc7tetratricopeptide repeat domain 70.016
Tnftumor necrosis factor0.014
Socs1suppressor of cytokine signaling 10.012
Dicer1Dicer1, Dcr-1 homolog (Drosophila)0.012
Ctla4cytotoxic T-lymphocyte-associated protein 40.012
Smad4MAD homolog 4 (Drosophila)0.012
Ccr7chemokine (C-C motif) receptor 70.011
Tnfrsf4tumor necrosis factor receptor superfamily, member 40.011
Nlrp3NLR family, pyrin domain containing 30.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PILRApaired immunoglobin-like type 2 receptor alpha0.999
LILRB2leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 20.998
LILRA6leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 60.998
LILRB1leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 10.641
LILRA1leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 10.568
LILRB3leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 30.376
HK3hexokinase 3 (white cell)0.363
LILRA2leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 20.349
PTAFRplatelet-activating factor receptor0.234
CSKc-src tyrosine kinase0.087
SIGLEC7sialic acid binding Ig-like lectin 70.074
HLA-Gmajor histocompatibility complex, class I, G0.055
VSIG4V-set and immunoglobulin domain containing 40.054
TREM1triggering receptor expressed on myeloid cells 10.048
TYMPthymidine phosphorylase0.048
CCR1chemokine (C-C motif) receptor 10.043
LILRA3leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 30.041
HDAC7histone deacetylase 70.037
SIGLEC9sialic acid binding Ig-like lectin 90.037
NLRP3NLR family, pyrin domain containing 30.036
SIRPB1signal-regulatory protein beta 10.032
IKZF3IKAROS family zinc finger 3 (Aiolos)0.029
FCN1ficolin (collagen/fibrinogen domain containing) 10.026
AOAHacyloxyacyl hydrolase (neutrophil)0.026
FPR2formyl peptide receptor 20.025
NOD2nucleotide-binding oligomerization domain containing 20.025
PTPN6protein tyrosine phosphatase, non-receptor type 60.024
HDAC9histone deacetylase 90.020
CD86CD86 molecule0.019
FPR1formyl peptide receptor 10.019
IL1RNinterleukin 1 receptor antagonist0.019
PLEKpleckstrin0.018
TLR8toll-like receptor 80.018
FCARFc fragment of IgA, receptor for0.017
PIK3R5phosphoinositide-3-kinase, regulatory subunit 50.017
LILRB4leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 40.016
FCGR2CFc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)0.015
CD300CCD300c molecule0.014
CD163CD163 molecule0.014
S100A12S100 calcium binding protein A120.013
SIGLEC1sialic acid binding Ig-like lectin 1, sialoadhesin0.013
MARCOmacrophage receptor with collagenous structure0.013
RASSF4Ras association (RalGDS/AF-6) domain family member 40.012
ASGR2asialoglycoprotein receptor 20.012
CLEC5AC-type lectin domain family 5, member A0.012
CMKLR1chemokine-like receptor 10.011
KIR3DL2killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 20.011
SNCAsynuclein, alpha (non A4 component of amyloid precursor)0.011
AQP9aquaporin 90.011
SLC11A1solute carrier family 11 (proton-coupled divalent metal ion transporters), member 10.011
CD300ACD300a molecule0.011
CR1complement component (3b/4b) receptor 1 (Knops blood group)0.011
KAT5K(lysine) acetyltransferase 50.010
CFPcomplement factor properdin0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism