The network for 'positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway

Any process that activates or increases the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.

NameDescriptionProbabilityFunc Analog Organism
Rab18RAB18, member RAS oncogene family0.945
Tmem30atransmembrane protein 30A0.800
Pja2praja 2, RING-H2 motif containing0.690
Nptnneuroplastin0.479
Ndfip1Nedd4 family interacting protein 10.435
Pcmtd1protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 10.318
Golph3golgi phosphoprotein 30.214
Fbxl3F-box and leucine-rich repeat protein 30.143
Usp9xubiquitin specific peptidase 9, X chromosome0.083
Rbl2retinoblastoma-like 20.082
Rnf11ring finger protein 110.079
Prkar1aprotein kinase, cAMP dependent regulatory, type I, alpha0.078
Slmapsarcolemma associated protein0.075
Itfg1integrin alpha FG-GAP repeat containing 10.074
Snx13sorting nexin 130.050
Rab5aRAB5A, member RAS oncogene family0.047
Mef2amyocyte enhancer factor 2A0.044
Castcalpastatin0.042
Pcmtd2protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 20.038
Laptm4alysosomal-associated protein transmembrane 4A0.037
Ranbp9RAN binding protein 90.037
Serinc1serine incorporator 10.035
Dynlt3dynein light chain Tctex-type 30.034
Mtmr6myotubularin related protein 60.034
Snx14sorting nexin 140.032
Ccnicyclin I0.031
Yipf4Yip1 domain family, member 40.030
Tmed7transmembrane emp24 protein transport domain containing 70.029
Ccng1cyclin G10.029
Sel1lsel-1 suppressor of lin-12-like (C. elegans)0.027
Rin2Ras and Rab interactor 20.027
Lin7clin-7 homolog C (C. elegans)0.027
Sh3bgrlSH3-binding domain glutamic acid-rich protein like0.027
Hiatl1hippocampus abundant transcript-like 10.025
Dnajb4DnaJ (Hsp40) homolog, subfamily B, member 40.025
Lamp2lysosomal-associated membrane protein 20.025
Cpeb4cytoplasmic polyadenylation element binding protein 40.025
Atf6activating transcription factor 60.024
Stx12syntaxin 120.024
Crbncereblon0.024
Rmnd5arequired for meiotic nuclear division 5 homolog A (S. cerevisiae)0.023
Cftrcystic fibrosis transmembrane conductance regulator homolog0.021
Oxr1oxidation resistance 10.021
Pdx1pancreatic and duodenal homeobox 10.020
Lmbrd1LMBR1 domain containing 10.019
Ahcyl1S-adenosylhomocysteine hydrolase-like 10.018
AW549877expressed sequence AW5498770.017
Abca1ATP-binding cassette, sub-family A (ABC1), member 10.016
Acsl4acyl-CoA synthetase long-chain family member 40.016
Ubl3ubiquitin-like 30.016
Mdm2transformed mouse 3T3 cell double minute 20.015
Rnf13ring finger protein 130.015
Mgea5meningioma expressed antigen 5 (hyaluronidase)0.015
Nedd4neural precursor cell expressed, developmentally down-regulated 40.015
Mat2bmethionine adenosyltransferase II, beta0.015
Wlswntless homolog (Drosophila)0.015
Ccng2cyclin G20.015
Map4k5mitogen-activated protein kinase kinase kinase kinase 50.014
Mfn2mitofusin 20.014
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.013
Cpeb2cytoplasmic polyadenylation element binding protein 20.013
Rbm18RNA binding motif protein 180.013
Nr3c1nuclear receptor subfamily 3, group C, member 10.012
Klhl24kelch-like 24 (Drosophila)0.012
Adam9a disintegrin and metallopeptidase domain 9 (meltrin gamma)0.011
Fbxo8F-box protein 80.011
Tspyl1testis-specific protein, Y-encoded-like 10.011
2700089E24RikRIKEN cDNA 2700089E24 gene0.011
Wdr26WD repeat domain 260.011
Gopcgolgi associated PDZ and coiled-coil motif containing0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism