The network for 'epithelial cell morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

epithelial cell morphogenesis

The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state.

NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog1.000
Fgfr2fibroblast growth factor receptor 20.999
Pax2paired box gene 20.998
Otx2orthodenticle homolog 2 (Drosophila)0.996
Msx1homeobox, msh-like 10.991
Gli3GLI-Kruppel family member GLI30.989
Hand1heart and neural crest derivatives expressed transcript 10.984
Fgfr1fibroblast growth factor receptor 10.952
En1engrailed 10.946
Hoxd11homeobox D110.944
Ascl1achaete-scute complex homolog 1 (Drosophila)0.932
Trp63transformation related protein 630.931
Fgf8fibroblast growth factor 80.929
Nognoggin0.903
Pax6paired box gene 60.900
Neurod1neurogenic differentiation 10.898
Fgf10fibroblast growth factor 100.888
Pax3paired box gene 30.882
Emx2empty spiracles homolog 2 (Drosophila)0.882
Hoxa13homeobox A130.872
Alx4aristaless-like homeobox 40.870
Id3inhibitor of DNA binding 30.864
Lhx1LIM homeobox protein 10.859
Wnt5awingless-related MMTV integration site 5A0.852
Dlx5distal-less homeobox 50.849
Foxc2forkhead box C20.835
Hoxa11homeobox A110.834
Vaspvasodilator-stimulated phosphoprotein0.809
Gli2GLI-Kruppel family member GLI20.795
Ctnnb1catenin (cadherin associated protein), beta 10.794
Sox2SRY-box containing gene 20.761
Tbx15T-box 150.759
Lef1lymphoid enhancer binding factor 10.753
Tbrachyury0.747
Pax8paired box gene 80.727
Hoxd13homeobox D130.724
Msx2homeobox, msh-like 20.717
Eya1eyes absent 1 homolog (Drosophila)0.716
Adrb1adrenergic receptor, beta 10.712
Fgf3fibroblast growth factor 30.700
Six4sine oculis-related homeobox 4 homolog (Drosophila)0.698
Hes1hairy and enhancer of split 1 (Drosophila)0.691
Rargretinoic acid receptor, gamma0.686
Neurog1neurogenin 10.666
Wnt4wingless-related MMTV integration site 40.662
Prrx1paired related homeobox 10.656
Pou3f3POU domain, class 3, transcription factor 30.634
Foxc1forkhead box C10.633
Emx1empty spiracles homolog 1 (Drosophila)0.629
Hoxa2homeobox A20.619
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.611
Nr5a1nuclear receptor subfamily 5, group A, member 10.604
Pitx2paired-like homeodomain transcription factor 20.601
Bmp7bone morphogenetic protein 70.598
Arandrogen receptor0.583
Otx1orthodenticle homolog 1 (Drosophila)0.581
Tcfap2atranscription factor AP-2, alpha0.580
Wnt3awingless-related MMTV integration site 3A0.557
Sox9SRY-box containing gene 90.537
Hoxa10homeobox A100.536
Gab1growth factor receptor bound protein 2-associated protein 10.512
Pax9paired box gene 90.498
Hoxa1homeobox A10.495
Dlx1distal-less homeobox 10.492
Ror2receptor tyrosine kinase-like orphan receptor 20.483
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.481
Lmx1aLIM homeobox transcription factor 1 alpha0.480
Sall4sal-like 4 (Drosophila)0.478
Vax1ventral anterior homeobox containing gene 10.477
Id1inhibitor of DNA binding 10.475
Adra2badrenergic receptor, alpha 2b0.475
Smad6MAD homolog 6 (Drosophila)0.473
Hoxb1homeobox B10.469
Gdnfglial cell line derived neurotrophic factor0.465
Sox1SRY-box containing gene 10.460
Foxg1forkhead box G10.453
Lama5laminin, alpha 50.433
Six3sine oculis-related homeobox 3 homolog (Drosophila)0.412
Gbx2gastrulation brain homeobox 20.406
Tcfap2ctranscription factor AP-2, gamma0.404
Dkk1dickkopf homolog 1 (Xenopus laevis)0.403
Glra1glycine receptor, alpha 1 subunit0.393
Pitx1paired-like homeodomain transcription factor 10.389
Ptenphosphatase and tensin homolog0.386
Nr0b1nuclear receptor subfamily 0, group B, member 10.355
Gas1growth arrest specific 10.337
Pnpla2patatin-like phospholipase domain containing 20.333
Kcnj6potassium inwardly-rectifying channel, subfamily J, member 60.331
Myf5myogenic factor 50.330
Foxd1forkhead box D10.327
Dlx6distal-less homeobox 60.325
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.325
Sall1sal-like 1 (Drosophila)0.323
Onecut1one cut domain, family member 10.323
Wnt10bwingless related MMTV integration site 10b0.322
Sim2single-minded homolog 2 (Drosophila)0.322
Bcl2B-cell leukemia/lymphoma 20.320
Nab1Ngfi-A binding protein 10.319
Klklotho0.317
Cnn2calponin 20.306
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
pry-1Protein PRY-10.048
xpo-1Protein XPO-10.047
myo-3Protein MYO-30.045
pxf-1Protein PXF-10.043
kin-4Protein KIN-40.033
col-111Protein COL-1110.031
bar-1Protein BAR-10.031
mdt-29Protein MDT-290.030
dnc-1Protein DNC-10.029
lin-13Protein LIN-130.028
ZK688.5Protein ZK688.50.027
ZK180.6Protein ZK180.60.027
ztf-19Protein ZTF-190.027
rig-6Protein RIG-60.026
CELE_M01B12.4Protein M01B12.40.026
F37B12.1Protein F37B12.10.025
lat-1Protein LAT-10.025
bed-3Protein BED-30.024
clec-180Protein CLEC-1800.024
daf-19Protein DAF-190.023
pac-1Protein PAC-10.022
pop-1Protein POP-10.022
mep-1Protein MEP-10.021
col-128Protein COL-1280.021
F35H10.10Protein F35H10.100.021
T16G1.2Protein T16G1.20.020
lir-1Protein LIR-10.020
smgl-2Protein SMGL-20.020
grd-2Protein GRD-20.020
lin-7Protein LIN-70.020
che-13Protein CHE-130.020
sin-3Protein SIN-30.020
let-711Protein LET-7110.020
fust-1Protein FUST-10.019
R07B1.5Protein R07B1.50.019
tlk-1Protein TLK-10.019
tni-1Protein TNI-10.019
emb-30Protein EMB-300.018
zfp-1Protein ZFP-10.018
B0001.5Protein B0001.50.018
par-6Protein PAR-60.018
lin-66Protein LIN-660.018
C02B10.5Protein C02B10.50.017
osm-9Protein OSM-90.017
egl-5Protein EGL-50.017
ani-1Protein ANI-10.016
madf-5Protein MADF-50.016
R04B3.1Protein R04B3.10.016
che-2Protein CHE-20.016
chc-1Protein CHC-10.016
clr-1Protein CLR-10.016
mec-2Protein MEC-20.016
flh-2Protein FLH-20.016
C06E1.9Protein C06E1.90.016
acdh-6Protein ACDH-60.016
bli-1Protein BLI-10.015
ajm-1Protein AJM-10.015
F13B6.1Protein F13B6.10.015
osm-6Protein OSM-60.015
pup-2Protein PUP-20.015
zer-1Protein ZER-10.015
goa-1Protein GOA-10.015
osm-8Protein OSM-80.015
zfp-3Protein ZFP-30.015
osm-3Protein OSM-30.015
fhod-1Protein FHOD-10.015
nmy-1Protein NMY-10.015
alx-1Protein ALX-10.015
daf-10Protein DAF-100.014
CELE_M04F3.5Protein M04F3.50.014
oac-30Protein OAC-300.014
tam-1Protein TAM-10.014
daf-6Protein DAF-60.014
CELE_F28G4.4Protein F28G4.40.014
bre-3Protein BRE-30.014
set-2Protein SET-20.014
CELE_C32H11.8Protein C32H11.80.014
bbs-1Protein BBS-10.013
trr-1Protein TRR-10.013
jac-1Protein JAC-10.013
wnk-1Protein WNK-10.013
lgc-39Protein LGC-390.013
mltn-12Protein MLTN-120.013
ztf-17Protein ZTF-170.013
T23F2.2Protein T23F2.20.013
F46G11.2Protein F46G11.20.013
lea-1Protein LEA-10.013
tag-297Protein TAG-2970.013
dos-2Protein DOS-20.013
F56C9.10Protein F56C9.100.013
ZC373.4Protein ZC373.40.012
CELE_Y11D7A.5Protein Y11D7A.50.012
R07E3.6Protein R07E3.60.012
rig-4Protein RIG-40.012
CELE_T23F6.5Protein T23F6.50.012
set-16Protein SET-160.012
osm-12Protein OSM-120.012
CELE_K08D8.3Protein K08D8.30.012
C30C11.4Protein C30C11.40.012
mlt-10Protein MLT-100.012
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
osr2odd-skipped related 2 (Drosophila)0.918
bmp4bone morphogenetic protein 40.914
dlcdeltaC0.878
dladeltaA0.773
lmx1b.1LIM homeobox transcription factor 1, beta 10.764
notch3notch homolog 30.715
cdh2cadherin 2, neuronal0.660
pax8paired box gene 80.617
cxcr4achemokine (C-X-C motif) receptor 4a0.603
twist2twist20.558
pea3ETS-domain transcription factor pea30.556
ctnnb1catenin (cadherin-associated protein), beta 10.512
jag1bjagged 1b0.486
pax2apaired box gene 2a0.472
gyltl1bglycosyltransferase-like 1b0.456
notch1anotch homolog 1a0.440
slc12a2solute carrier family 12 (potassium/chloride transporters), member 20.436
etv2ets variant gene 20.414
cx43.4connexin 43.40.372
nkx3.2NK3 homeobox 20.370
shhasonic hedgehog a0.360
vcanaversican a0.357
hapln1ahyaluronan and proteoglycan link protein 1a0.352
llgl2lethal giant larvae homolog 2 (Drosophila)0.348
csf3rcolony stimulating factor 3 receptor (granulocyte)0.343
wnt5bwingless-type MMTV integration site family, member 5b0.339
cdh23cadherin-like 230.334
pitx3paired-like homeodomain transcription factor 30.282
pkd2polycystic kidney disease 20.274
krt8keratin 80.271
ptch2patched 20.263
cdh1cadherin 1, epithelial0.257
osr1odd-skipped related 1 (Drosophila)0.244
wwp2WW domain containing E3 ubiquitin protein ligase 20.238
dlddeltaD0.232
cxcl12bchemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)0.222
sox9aSRY-box containing gene 9a0.219
hnf1bbHNF1 homeobox Bb0.216
vgll4lvestigial like 4 like0.215
col2a1acollagen type II, alpha-1a0.214
atoh1aatonal homolog 1a0.212
wt1awilms tumor 1a0.208
hbbe3hemoglobin beta embryonic-30.207
dlbdeltaB0.205
wnt9awingless-type MMTV integration site family, member 9A0.203
pard6gbpar-6 partitioning defective 6 homolog gamma B (C. elegans)0.201
prkciprotein kinase C, iota0.201
tbx2bT-box 2b0.197
lamc1laminin, gamma 10.196
nrarpanotch-regulated ankyrin repeat protein a0.195
nog1noggin 10.193
hmx1H6 homeo box 10.175
hoxa13bhomeo box A13b0.169
jag2jagged 20.168
sim1asingle-minded homolog 1a (Drosophila)0.166
gna12guanine nucleotide binding protein (G protein) alpha 120.162
sox9bSRY-box containing gene 9b0.162
ptf1apancreas specific transcription factor, 1a0.162
tjp1tight junction protein 1 (zona occludens 1)0.160
cmybtranscription factor cmyb0.152
epha4aeph receptor A4a0.150
pcdh18aprotocadherin 18a0.149
jag1ajagged 1a0.148
plod1aprocollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1a0.146
fbn2bfibrillin 2b0.145
crb2acrumbs homolog 2a0.143
mmp9matrix metalloproteinase 90.141
hoxd4ahomeo box D4a0.140
copb2coatomer protein complex, subunit beta 20.139
sb:cb166sb:cb1660.138
myf6myogenic factor 60.134
ef1aelongation factor 1-alpha0.133
sb:cb81sb:cb810.130
coblcordon-bleu homolog (mouse)0.129
rykreceptor-like tyrosine kinase0.129
wnt11wingless-type MMTV integration site family, member 110.128
cyp26c1cytochrome P450, family 26, subfamily C, polypeptide 10.127
unc45aunc-45 homolog A (C. elegans)0.127
sox11bSRY-box containing gene 11b0.126
col11a1acollagen, type XI, alpha 1a0.125
btkBruton agammaglobulinemia tyrosine kinase0.125
sulf1sulfatase 10.124
mgpmatrix Gla protein0.123
dag1dystroglycan 10.123
gna13aguanine nucleotide binding protein (G protein), alpha 13a0.121
foxa1forkhead box A10.119
atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.117
krt18keratin 180.117
pwp2hPWP2 periodic tryptophan protein homolog (yeast)0.115
lamb1alaminin, beta 1a0.113
hey1hairy/enhancer-of-split related with YRPW motif 10.113
wnt2bbwingless-type MMTV integration site family, member 2Bb0.113
frem3Fras1 related extracellular matrix 30.110
ift57intraflagellar transport protein 570.108
wnt2bawingless-type MMTV integration site family, member 2Ba0.108
plod2procollagen-lysine, 2-oxoglutarate 5-dioxygenase 20.106
nrp1aneuropilin 1a0.105
neurog1neurogenin 10.104
sox2SRY-box containing gene 20.104
hmgcrb3-hydroxy-3-methylglutaryl-Coenzyme A reductase b0.104
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
nyonyobe0.550
crbcrumbs0.344
araaraucan0.339
dallydivision abnormally delayed0.326
Rho1CG8416 gene product from transcript CG8416-RB0.273
SerSerrate0.261
Vap-33-1CG5014 gene product from transcript CG5014-RB0.256
shashavenoid0.245
mminiature0.212
kniknirps0.211
fngfringe0.190
hhhedgehog0.185
bazbazooka0.181
Cdc42CG12530 gene product from transcript CG12530-RA0.152
chicchickadee0.150
armarmadillo0.143
ttktramtrack0.128
G-oalpha47AG protein oalpha 47A0.108
fforked0.105
par-1CG8201 gene product from transcript CG8201-RA0.100
shgshotgun0.083
elavembryonic lethal abnormal vision0.075
Rab11Rab-protein 110.069
rempAreduced mechanoreceptor potential A0.069
sqhspaghetti squash0.069
sxcsuper sex combs0.066
SoxNSoxNeuro0.065
sglsugarless0.064
norpAno receptor potential A0.063
mewmultiple edematous wings0.061
enengrailed0.061
coracoracle0.060
svshaven0.058
ococelliless0.056
nompCno mechanoreceptor potential C0.055
argosCG4531 gene product from transcript CG4531-RA0.049
wgwingless0.049
cicubitus interruptus0.048
NetBNetrin-B0.045
hthhomothorax0.045
frcfringe connection0.045
rorough0.044
kuzkuzbanian0.039
Tak1TGF-beta activated kinase 10.038
PoxnPox neuro0.037
sogshort gastrulation0.037
apapterous0.036
CG32556CG32556 gene product from transcript CG32556-RB0.035
p120ctnAdherens junction protein p1200.034
tyntrynity0.031
MtlMig-2-like0.030
mmymummy0.030
rokRho-kinase0.030
loqsloquacious0.029
elBelbow B0.029
bifbifocal0.028
Dhc64CDynein heavy chain 64C0.027
trctricornered0.026
snsinged0.026
flwflapwing0.026
otkoff-track0.026
vrivrille0.025
MoeMoesin0.025
amosabsent MD neurons and olfactory sensilla0.024
rhorhomboid0.024
MrtfMyocardin-related transcription factor0.024
liclicorne0.024
HLH4CHelix loop helix protein 4C0.024
dshdishevelled0.023
mavmaverick0.022
osoutstretched0.022
neoneyo0.022
AbiAbelson interacting protein0.021
AblAbl tyrosine kinase0.020
JhI-21CG12317 gene product from transcript CG12317-RB0.020
Spn100ASerpin 100A0.020
GmdGDP-mannose 4,6-dehydratase0.020
nompBno mechanoreceptor potential B0.020
dadaughterless0.020
pydpolychaetoid0.020
par-6CG5884 gene product from transcript CG5884-RA0.019
Z600CG17962 gene product from transcript CG17962-RA0.019
kelkelch0.019
sec23CG1250 gene product from transcript CG1250-RA0.019
lzlozenge0.019
diadiaphanous0.019
HemHEM-protein0.018
Lim1CG11354 gene product from transcript CG11354-RA0.018
ik2IkappaB kinase-like 20.018
emcextra macrochaetae0.017
zyeCG5847 gene product from transcript CG5847-RA0.017
cnocanoe0.017
aopanterior open0.017
smosmoothened0.016
invinvected0.016
PebProtein ejaculatory bulb0.016
nmonemo0.016
deltaCOPdelta-coatomer protein0.016
uspultraspiracle0.016
LanALaminin A0.016
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
TAL1T-cell acute lymphocytic leukemia 10.553
BMPR1Abone morphogenetic protein receptor, type IA0.487
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.324
GAS6growth arrest-specific 60.202
SORBS2sorbin and SH3 domain containing 20.153
PSEN1presenilin 10.150
FLNAfilamin A, alpha0.138
SMAD2SMAD family member 20.097
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.087
EGFRepidermal growth factor receptor0.086
WIPF1WAS/WASL interacting protein family, member 10.081
SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)0.078
IQGAP1IQ motif containing GTPase activating protein 10.066
CTTNcortactin0.060
ARPC2actin related protein 2/3 complex, subunit 2, 34kDa0.057
CTNND1catenin (cadherin-associated protein), delta 10.057
CAV1caveolin 1, caveolae protein, 22kDa0.051
MYH9myosin, heavy chain 9, non-muscle0.045
RHOAras homolog gene family, member A0.043
DNM2dynamin 20.043
GAB1GRB2-associated binding protein 10.042
ARHGAP1Rho GTPase activating protein 10.042
FSTL1follistatin-like 10.040
PTPN1protein tyrosine phosphatase, non-receptor type 10.038
MAPK8mitogen-activated protein kinase 80.036
DYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A0.034
IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor)0.033
MEOX1mesenchyme homeobox 10.032
TECPR1tectonin beta-propeller repeat containing 10.031
STAT5Asignal transducer and activator of transcription 5A0.028
PSEN2presenilin 2 (Alzheimer disease 4)0.028
CREBBPCREB binding protein0.028
ID3inhibitor of DNA binding 3, dominant negative helix-loop-helix protein0.027
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.027
SOS1son of sevenless homolog 1 (Drosophila)0.026
F11RF11 receptor0.024
ARPC3actin related protein 2/3 complex, subunit 3, 21kDa0.022
ARHGEF40Rho guanine nucleotide exchange factor (GEF) 400.020
BCAR1breast cancer anti-estrogen resistance 10.020
PKD2polycystic kidney disease 2 (autosomal dominant)0.020
NKX2-1NK2 homeobox 10.019
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.019
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.019
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.019
FAT1FAT tumor suppressor homolog 1 (Drosophila)0.019
ESR1estrogen receptor 10.018
RUNX1runt-related transcription factor 10.018
GLIS2GLIS family zinc finger 20.018
WNT3Awingless-type MMTV integration site family, member 3A0.018
SCYL2SCY1-like 2 (S. cerevisiae)0.017
PCOLCEprocollagen C-endopeptidase enhancer0.017
SPTBN1spectrin, beta, non-erythrocytic 10.017
SOX2SRY (sex determining region Y)-box 20.015
IFNAR2interferon (alpha, beta and omega) receptor 20.015
ITSN1intersectin 1 (SH3 domain protein)0.015
PICALMphosphatidylinositol binding clathrin assembly protein0.014
PTK2PTK2 protein tyrosine kinase 20.014
CSNK1Ecasein kinase 1, epsilon0.013
PKP4plakophilin 40.013
KLF13Kruppel-like factor 130.013
ARHGEF12Rho guanine nucleotide exchange factor (GEF) 120.013
DCAF7DDB1 and CUL4 associated factor 70.012
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.012
MYL12Amyosin, light chain 12A, regulatory, non-sarcomeric0.012
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.012
FLNBfilamin B, beta0.012
TSG101tumor susceptibility gene 1010.011
MUC1mucin 1, cell surface associated0.011
ROD1ROD1 regulator of differentiation 1 (S. pombe)0.011
JAK2Janus kinase 20.011
LATlinker for activation of T cells0.011
HEXDChexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing0.011
GRB2growth factor receptor-bound protein 20.011
DVL3dishevelled, dsh homolog 3 (Drosophila)0.010
DLG1discs, large homolog 1 (Drosophila)0.010
ZFPM1zinc finger protein, multitype 10.010
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Cpt2carnitine palmitoyltransferase 20.042
Acta2smooth muscle alpha-actin0.041
Id3inhibitor of DNA binding 30.030
Tln1talin 10.026
Tgfbr2transforming growth factor, beta receptor II0.022
Smad1SMAD family member 10.019
Tpm2tropomyosin 2, beta0.016
Bmp7bone morphogenetic protein 70.015
Tpm4tropomyosin 40.015
Stat1signal transducer and activator of transcription 10.015
Socs3suppressor of cytokine signaling 30.015
Cishcytokine inducible SH2-containing protein0.014
Lims1LIM and senescent cell antigen-like domains 10.013
Nek9NIMA (never in mitosis gene a)- related kinase 90.013
Nab1Ngfi-A binding protein 10.013
Prdm2PR domain containing 2, with ZNF domain0.013
Ptpn12protein tyrosine phosphatase, non-receptor type 120.012
Flt1FMS-related tyrosine kinase 10.011
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism