The network for 'regulation of thyroid hormone generation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of thyroid hormone generation

Any process that modulates the frequency, rate or extent of thyroid hormone generation.

NameDescriptionProbabilityFunc Analog Organism
Wnt9bwingless-type MMTV integration site 9B0.824
Slc26a4solute carrier family 26, member 40.642
Lmx1aLIM homeobox transcription factor 1 alpha0.625
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.529
Foxi1forkhead box I10.460
Pax2paired box gene 20.433
Fgf10fibroblast growth factor 100.318
Cdh23cadherin 23 (otocadherin)0.296
Hoxa11homeobox A110.290
Sprr2a2small proline-rich protein 2A20.250
Hoxb3homeobox B30.248
Hoxa1homeobox A10.228
Kcnq1potassium voltage-gated channel, subfamily Q, member 10.223
Thrbthyroid hormone receptor beta0.212
Duox2dual oxidase 20.212
Crb3crumbs homolog 3 (Drosophila)0.197
Emx2empty spiracles homolog 2 (Drosophila)0.195
Nkx2-1NK2 homeobox 10.175
Lhx1LIM homeobox protein 10.146
Lef1lymphoid enhancer binding factor 10.145
Vangl2vang-like 2 (van gogh, Drosophila)0.133
Eya1eyes absent 1 homolog (Drosophila)0.125
Elf3E74-like factor 30.096
Sprr1bsmall proline-rich protein 1B0.095
Wt1Wilms tumor 1 homolog0.095
Pou4f3POU domain, class 4, transcription factor 30.093
Srrm4serine/arginine repetitive matrix 40.090
Fgf3fibroblast growth factor 30.084
Cldn4claudin 40.083
Mlphmelanophilin0.082
Shhsonic hedgehog0.082
Hoxd3homeobox D30.080
Pigrpolymeric immunoglobulin receptor0.078
Tctex1d4Tctex1 domain containing 40.074
Kcne1potassium voltage-gated channel, Isk-related subfamily, member 10.074
Foxe1forkhead box E10.070
Tbx1T-box 10.064
Pax8paired box gene 80.062
Tbx10T-box 100.061
Slc28a3solute carrier family 28 (sodium-coupled nucleoside transporter), member 30.058
Hand1heart and neural crest derivatives expressed transcript 10.057
Tshrthyroid stimulating hormone receptor0.056
Umoduromodulin0.056
Foxn1forkhead box N10.054
Duoxa1dual oxidase maturation factor 10.050
Prlrprolactin receptor0.050
Tgthyroglobulin0.049
Rargretinoic acid receptor, gamma0.049
Nppbnatriuretic peptide type B0.049
Alox8arachidonate 8-lipoxygenase0.048
Gsdmcgasdermin C0.048
Trim29tripartite motif-containing 290.047
RhcgRhesus blood group-associated C glycoprotein0.047
Cyp2c29cytochrome P450, family 2, subfamily c, polypeptide 290.045
2310002J15RikRIKEN cDNA 2310002J15 gene0.045
Iglimmunoglobulin lambda chain complex0.043
Krt14keratin 140.042
Slc17a8solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 80.041
Krt4keratin 40.039
Gata3GATA binding protein 30.039
Prss22protease, serine, 220.039
SspoSCO-spondin0.039
Fam83ffamily with sequence similarity 83, member F0.037
Pplperiplakin0.037
1600029D21RikRIKEN cDNA 1600029D21 gene0.037
Cdcp1CUB domain containing protein 10.037
Aicdaactivation-induced cytidine deaminase0.036
Dkk1dickkopf homolog 1 (Xenopus laevis)0.036
Lgr4leucine-rich repeat-containing G protein-coupled receptor 40.035
Il1f6interleukin 1 family, member 60.035
Tmprss13transmembrane protease, serine 130.035
Nr5a1nuclear receptor subfamily 5, group A, member 10.035
Btn1a1butyrophilin, subfamily 1, member A10.035
Hoxb1homeobox B10.034
Wnt3awingless-related MMTV integration site 3A0.034
Gbx2gastrulation brain homeobox 20.034
Hoxd11homeobox D110.033
Arandrogen receptor0.033
Il17ainterleukin 17A0.033
Slc12a1solute carrier family 12, member 10.032
Klk7kallikrein related-peptidase 7 (chymotryptic, stratum corneum)0.032
Casp14caspase 140.031
S100a14S100 calcium binding protein A140.031
Edn2endothelin 20.030
Mmp20matrix metallopeptidase 20 (enamelysin)0.030
Lhcgrluteinizing hormone/choriogonadotropin receptor0.030
RhagRhesus blood group-associated A glycoprotein0.030
Krt75keratin 750.030
Cldn8claudin 80.029
Pspparotid secretory protein0.029
Prl8a8prolactin family 8, subfamily a, member 810.029
Clrn3clarin 30.028
Tbrachyury0.028
Fgf8fibroblast growth factor 80.028
Pou2af1POU domain, class 2, associating factor 10.027
A330049M08RikRIKEN cDNA A330049M08 gene0.027
Tmem54transmembrane protein 540.027
Sprr2hsmall proline-rich protein 2H0.027
Matn3matrilin 30.026
Rararetinoic acid receptor, alpha0.026
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
TAL1T-cell acute lymphocytic leukemia 11.000
MEOX1mesenchyme homeobox 11.000
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)1.000
NKX2-1NK2 homeobox 11.000
RUNX1runt-related transcription factor 10.988
TBX5T-box 50.988
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.987
ITGA2Bintegrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)0.903
KLF13Kruppel-like factor 130.886
GATA1GATA binding protein 1 (globin transcription factor 1)0.726
BBS1Bardet-Biedl syndrome 10.701
GATA2GATA binding protein 20.635
SPIBSpi-B transcription factor (Spi-1/PU.1 related)0.535
ZFPM1zinc finger protein, multitype 10.504
KLF1Kruppel-like factor 1 (erythroid)0.431
GATA4GATA binding protein 40.427
NR5A1nuclear receptor subfamily 5, group A, member 10.424
WNT7Awingless-type MMTV integration site family, member 7A0.334
WT1Wilms tumor 10.325
PAX7paired box 70.311
LMO2LIM domain only 2 (rhombotin-like 1)0.235
HNF1BHNF1 homeobox B0.197
LHX1LIM homeobox 10.192
DAXXdeath-domain associated protein0.189
ZBTB16zinc finger and BTB domain containing 160.178
COL2A1collagen, type II, alpha 10.170
ALX4ALX homeobox 40.161
SIM2single-minded homolog 2 (Drosophila)0.149
SFRP5secreted frizzled-related protein 50.144
MYL4myosin, light chain 4, alkali; atrial, embryonic0.137
CLCNKBchloride channel Kb0.124
ALX3ALX homeobox 30.123
CBFA2T3core-binding factor, runt domain, alpha subunit 2; translocated to, 30.113
PAX3paired box 30.109
FOXE1forkhead box E1 (thyroid transcription factor 2)0.106
HNF1AHNF1 homeobox A0.102
GATA5GATA binding protein 50.096
HOXA11homeobox A110.096
BBS2Bardet-Biedl syndrome 20.096
MYOD1myogenic differentiation 10.087
FOXN4forkhead box N40.083
GLP1Rglucagon-like peptide 1 receptor0.081
GP1BAglycoprotein Ib (platelet), alpha polypeptide0.078
BHLHE23basic helix-loop-helix family, member e230.077
BBS4Bardet-Biedl syndrome 40.072
PYYpeptide YY0.072
ANK1ankyrin 1, erythrocytic0.071
SP1Sp1 transcription factor0.069
KLHL35kelch-like 35 (Drosophila)0.068
CRHR1corticotropin releasing hormone receptor 10.067
HOXD9homeobox D90.066
LTKleukocyte receptor tyrosine kinase0.064
PAX2paired box 20.064
SLC30A3solute carrier family 30 (zinc transporter), member 30.059
LBX1ladybird homeobox 10.055
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.054
TBX1T-box 10.053
HOXB13homeobox B130.052
NKX3-2NK3 homeobox 20.051
EMX1empty spiracles homeobox 10.051
ETS1v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)0.050
CYP26A1cytochrome P450, family 26, subfamily A, polypeptide 10.049
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit0.048
HES2hairy and enhancer of split 2 (Drosophila)0.047
TLX1T-cell leukemia homeobox 10.047
SLC6A2solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 20.046
HOXB9homeobox B90.046
PAX5paired box 50.044
CDX2caudal type homeobox 20.043
HOXC5homeobox C50.042
HDGFL1hepatoma derived growth factor-like 10.040
TBX21T-box 210.040
NKX2-8NK2 homeobox 80.038
MESP1mesoderm posterior 1 homolog (mouse)0.037
HOXC11homeobox C110.036
ALAS2aminolevulinate, delta-, synthase 20.036
DHHdesert hedgehog0.036
ICAM4intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)0.035
SLC5A5solute carrier family 5 (sodium iodide symporter), member 50.035
CALCAcalcitonin-related polypeptide alpha0.035
OTPorthopedia homeobox0.035
RHAGRh-associated glycoprotein0.034
FGF4fibroblast growth factor 40.033
RASSF1Ras association (RalGDS/AF-6) domain family member 10.033
NKX3-1NK3 homeobox 10.032
LYL1lymphoblastic leukemia derived sequence 10.032
AMHR2anti-Mullerian hormone receptor, type II0.030
HOXD1homeobox D10.030
BNC1basonuclin 10.029
PNMTphenylethanolamine N-methyltransferase0.028
HOXD12homeobox D120.028
APC2adenomatosis polyposis coli 20.028
POU4F1POU class 4 homeobox 10.028
LMX1BLIM homeobox transcription factor 1, beta0.028
FGF3fibroblast growth factor 30.028
TT, brachyury homolog (mouse)0.027
FOXL2forkhead box L20.027
HAND1heart and neural crest derivatives expressed 10.027
EVX1even-skipped homeobox 10.026
MEOX2mesenchyme homeobox 20.026
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism