The network for 'trna splicing via endonucleolytic cleavage and ligation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

trna splicing via endonucleolytic cleavage and ligation

Splicing of tRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.

NameDescriptionProbabilityFunc Analog Organism
Cct4chaperonin containing Tcp1, subunit 4 (delta)0.081
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
EIF2B2eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa0.500
TMEM126Atransmembrane protein 126A0.242
RPL26L1ribosomal protein L26-like 10.197
C14orf166chromosome 14 open reading frame 1660.128
BTF3basic transcription factor 30.068
GLO1glyoxalase I0.065
EIF3Heukaryotic translation initiation factor 3, subunit H0.044
NME7non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)0.030
DDX1DEAD (Asp-Glu-Ala-Asp) box polypeptide 10.023
NSA2NSA2 ribosome biogenesis homolog (S. cerevisiae)0.019
MRPS22mitochondrial ribosomal protein S220.019
EIF2B3eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa0.019
FKBP3FK506 binding protein 3, 25kDa0.017
RPL36ALribosomal protein L36a-like0.017
GPN1GPN-loop GTPase 10.015
TIMM9translocase of inner mitochondrial membrane 9 homolog (yeast)0.014
TTC1tetratricopeptide repeat domain 10.013
RARSarginyl-tRNA synthetase0.012
UCHL3ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)0.012
RWDD1RWD domain containing 10.012
CCT4chaperonin containing TCP1, subunit 4 (delta)0.011
PSMC1proteasome (prosome, macropain) 26S subunit, ATPase, 10.011
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism