The network for 'establishment of pigment granule localization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

establishment of pigment granule localization

The directed movement of a pigment granule to a specific location.

NameDescriptionProbabilityFunc Analog Organism
Bbs1Bardet-Biedl syndrome 1 (human)0.993
Lystlysosomal trafficking regulator0.972
Mitfmicrophthalmia-associated transcription factor0.680
Rab27aRAB27A, member RAS oncogene family0.625
Hps1Hermansky-Pudlak syndrome 1 homolog (human)0.330
Hps5Hermansky-Pudlak syndrome 5 homolog (human)0.175
Ap3b1adaptor-related protein complex 3, beta 1 subunit0.132
Prf1perforin 1 (pore forming protein)0.129
Rab11aRAB11a, member RAS oncogene family0.124
Stx12syntaxin 120.119
Vapavesicle-associated membrane protein, associated protein A0.113
Tyrp1tyrosinase-related protein 10.106
Thrbthyroid hormone receptor beta0.092
Rab38RAB38, member of RAS oncogene family0.079
Arl6ADP-ribosylation factor-like 60.061
Csnk1g2casein kinase 1, gamma 20.058
Bbs5Bardet-Biedl syndrome 5 (human)0.057
Ush1gUsher syndrome 1G homolog (human)0.056
Ap3d1adaptor-related protein complex 3, delta 1 subunit0.053
Ttc8tetratricopeptide repeat domain 80.049
Hps6Hermansky-Pudlak syndrome 60.047
Oca2oculocutaneous albinism II0.045
Rab6RAB6, member RAS oncogene family0.043
RhebRas homolog enriched in brain0.042
Kcnq1potassium voltage-gated channel, subfamily Q, member 10.037
Atp6v1c1ATPase, H+ transporting, lysosomal V1 subunit C10.037
Bbs7Bardet-Biedl syndrome 7 (human)0.036
Bbs9Bardet-Biedl syndrome 9 (human)0.035
Mobkl3MOB1, Mps One Binder kinase activator-like 3 (yeast)0.035
Cldn2claudin 20.033
Elf3E74-like factor 30.032
Myo5amyosin VA0.032
Rab5aRAB5A, member RAS oncogene family0.031
Sh3glb2SH3-domain GRB2-like endophilin B20.031
8430410K20RikRIKEN cDNA 8430410K20 gene0.031
Pef1penta-EF hand domain containing 10.030
Drap1Dr1 associated protein 1 (negative cofactor 2 alpha)0.028
Rnf103ring finger protein 1030.028
Ppp1cbprotein phosphatase 1, catalytic subunit, beta isoform0.027
Dnajb9DnaJ (Hsp40) homolog, subfamily B, member 90.027
Mlf2myeloid leukemia factor 20.027
Actr3ARP3 actin-related protein 3 homolog (yeast)0.027
Pi4kbphosphatidylinositol 4-kinase, catalytic, beta polypeptide0.026
Tmem30atransmembrane protein 30A0.025
Rab25RAB25, member RAS oncogene family0.025
Crb3crumbs homolog 3 (Drosophila)0.025
Rnf11ring finger protein 110.024
Cltcclathrin, heavy polypeptide (Hc)0.024
Cpeb4cytoplasmic polyadenylation element binding protein 40.023
Chmp5chromatin modifying protein 50.023
Prr15proline rich 150.023
Atp6v1dATPase, H+ transporting, lysosomal V1 subunit D0.022
Ift74intraflagellar transport 74 homolog (Chlamydomonas)0.022
Hps3Hermansky-Pudlak syndrome 3 homolog (human)0.021
Stx7syntaxin 70.021
Tbk1TANK-binding kinase 10.021
Vamp4vesicle-associated membrane protein 40.021
Hoxd13homeobox D130.020
Ap2m1adaptor protein complex AP-2, mu10.020
Tax1bp1Tax1 (human T-cell leukemia virus type I) binding protein 10.019
Sgtasmall glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha0.019
Kitkit oncogene0.019
S1pr2sphingosine-1-phosphate receptor 20.019
Bag6BCL2-associated athanogene 60.018
Cldn4claudin 40.018
Ppp2caprotein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform0.018
Atp6ap2ATPase, H+ transporting, lysosomal accessory protein 20.017
Tff3trefoil factor 3, intestinal0.017
Rnf115ring finger protein 1150.017
Med16mediator complex subunit 160.017
Mtmr6myotubularin related protein 60.017
Aesamino-terminal enhancer of split0.016
Fbxw5F-box and WD-40 domain protein 50.016
Fkbp8FK506 binding protein 80.016
Add1adducin 1 (alpha)0.016
Btbd10BTB (POZ) domain containing 100.016
Sec23aSEC23A (S. cerevisiae)0.016
Plcg1phospholipase C, gamma 10.016
Sytl5synaptotagmin-like 50.016
Cdhr5cadherin-related family member 50.015
Dctn1dynactin 10.015
C78339expressed sequence C783390.015
Cldn3claudin 30.015
Rab2aRAB2A, member RAS oncogene family0.015
Grb7growth factor receptor bound protein 70.015
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.014
Gpi1glucose phosphate isomerase 10.014
Calm1calmodulin 10.014
Abp1amiloride binding protein 1 (amine oxidase, copper-containing)0.014
Tmprss2transmembrane protease, serine 20.014
Ehfets homologous factor0.014
Sept7septin 70.014
Apoa1apolipoprotein A-I0.014
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
pomcaproopiomelanocortin a0.906
tshbthyroid stimulating hormone, beta subunit0.346
mlphbmelanophilin b0.172
kif17kinesin family member 170.158
cx41.8connexin 41.80.151
kcnj13potassium inwardly-rectifying channel, subfamily J, member 130.121
bbs2Bardet-Biedl syndrome 20.104
acvr1bactivin A receptor, type IB0.084
bonbonnie and clyde0.078
mitfbmicrophthalmia-associated transcription factor b0.076
adm2adrenomedullin 20.072
pou1f1POU domain, class 1, transcription factor 10.062
ift80intraflagellar transport 80 homolog (Chlamydomonas)0.053
arf2ADP-ribosylation factor 20.052
tctex1d2Tctex1 domain containing 20.051
dact2dapper homolog 2, antagonist of beta-catenin (xenopus)0.046
esyt3extended synaptotagmin-like protein 30.042
scamp2secretory carrier membrane protein 20.037
tfap2etranscription factor AP-2 epsilon0.035
snx6sorting nexin 60.035
abcc8ATP-binding cassette, sub-family C (CFTR/MRP), member 80.031
nr1d4anuclear receptor subfamily 1, group D, member 4a0.028
taf3TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto0.028
tyrp1tyrosinase-related protein 10.027
cgaglycoprotein hormones, alpha polypeptide0.027
irx4biroquois homeobox protein 4b0.027
mks1meckel syndrome, type 10.025
ift57intraflagellar transport protein 570.025
crmp1collapsin response mediator protein 10.025
oaz2bornithine decarboxylase antizyme 2b0.025
smtlasomatolactin alpha0.024
styk1serine/threonine/tyrosine kinase 10.024
jak3Janus kinase 3 (a protein tyrosine kinase, leukocyte)0.024
cc2d2acoiled-coil and C2 domain containing 2A0.024
atl1atlastin GTPase 10.023
fgf20afibroblast growth factor 20a0.023
foxj1bforkhead box J1b0.023
cdh10cadherin 10, type 2 (T2-cadherin)0.023
dyrk1bdual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B0.022
tax1bp3Tax1 (human T-cell leukemia virus type I) binding protein 30.022
atoh7atonal homolog 70.022
unc119bunc-119 homolog b (C. elegans)0.022
ncor2nuclear receptor co-repressor 20.022
cluap1clusterin associated protein 10.021
elovl4belongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4b0.021
nphs2nephrosis 2, idiopathic, steroid-resistant (podocin)0.021
arpc5aactin related protein 2/3 complex, subunit 5A0.020
LOC567405novel protein similar to vertebrate megakaryocyte-associated tyrosine kinase (MATK)0.020
wdr16WD repeat domain 160.020
stat5.2signal transducer and activator of transcription 5.20.020
ccdc113coiled-coil domain containing 1130.020
glra4bglycine receptor, alpha 4b0.020
radilRap GTPase interactor0.019
kctd12.1potassium channel tetramerisation domain containing 12.10.019
ctsl1bcathepsin L, 1 b0.019
tmem199transmembrane protein 1990.019
bbs4Bardet-Biedl syndrome 40.019
ube2g2ubiquitin-conjugating enzyme E2G 20.018
og9xOG9 homeobox gene0.018
cfl2lcofilin 2, like0.018
dcdc2bdoublecortin domain containing 2B0.018
dctn1adynactin 1a0.018
ttc26tetratricopeptide repeat domain 260.017
varsvalyl-tRNA synthetase0.017
arl2bpADP-ribosylation factor-like 2 binding protein0.017
fshbfollicle stimulating hormone, beta polypeptide0.017
copb2coatomer protein complex, subunit beta 20.017
odc1ornithine decarboxylase 10.017
arl3ADP-ribosylation factor-like 30.017
ube2aubiquitin-conjugating enzyme E2A (RAD6 homolog)0.017
pdzd7aPDZ domain containing 7a0.016
igfbp2binsulin-like growth factor binding protein 2b0.016
rbm22RNA binding motif protein 220.016
rap1bRAS related protein 1b0.016
lrpap1low density lipoprotein receptor-related protein associated protein 10.016
appl1adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 10.016
dnm2dynamin 20.016
arl6ADP-ribosylation factor-like 60.016
snx12sorting nexin 120.015
cdh4cadherin 4, retinal0.015
ntrk3bneurotrophic tyrosine kinase, receptor, type 3b0.015
top2btopoisomerase (DNA) II beta0.015
sult3st2sulfotransferase family 3, cytosolic sulfotransferase 20.015
tmf1TATA element modulatory factor 10.015
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
BLOC1S2biogenesis of lysosomal organelles complex-1, subunit 20.747
DTNBP1dystrobrevin binding protein 10.440
CTNND1catenin (cadherin-associated protein), delta 10.265
OCRLoculocerebrorenal syndrome of Lowe0.075
JUPjunction plakoglobin0.041
MUTEDmuted homolog (mouse)0.036
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.030
PLDNpallidin homolog (mouse)0.026
BLOC1S1biogenesis of lysosomal organelles complex-1, subunit 10.023
RAB6ARAB6A, member RAS oncogene family0.017
DSG2desmoglein 20.014
BBS2Bardet-Biedl syndrome 20.012
RABIFRAB interacting factor0.011
RAB5ARAB5A, member RAS oncogene family0.011
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.011
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism