The network for 'regulation of actin filament length' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of actin filament length

Any process that controls the length of actin filaments in a cell.

NameDescriptionProbabilityFunc Analog Organism
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide1.000
Rac1RAS-related C3 botulinum substrate 10.996
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.995
Cttncortactin0.994
Actr3ARP3 actin-related protein 3 homolog (yeast)0.993
Wdr1WD repeat domain 10.991
Vaspvasodilator-stimulated phosphoprotein0.988
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.983
Capzbcapping protein (actin filament) muscle Z-line, beta0.978
Arpc4actin related protein 2/3 complex, subunit 40.974
Msnmoesin0.968
BlnkB-cell linker0.945
Dnm1dynamin 10.935
Enahenabled homolog (Drosophila)0.931
Efnb2ephrin B20.907
Actbactin, beta0.906
Dlg4discs, large homolog 4 (Drosophila)0.881
Cltcclathrin, heavy polypeptide (Hc)0.858
Akt1thymoma viral proto-oncogene 10.847
Abi1abl-interactor 10.832
Pfn2profilin 20.825
Ldb3LIM domain binding 30.774
Actg1actin, gamma, cytoplasmic 10.770
FynFyn proto-oncogene0.769
Mapkap1mitogen-activated protein kinase associated protein 10.768
Prkceprotein kinase C, epsilon0.753
Pfn1profilin 10.725
Grin2bglutamate receptor, ionotropic, NMDA2B (epsilon 2)0.713
Mtormechanistic target of rapamycin (serine/threonine kinase)0.703
Rhoaras homolog gene family, member A0.703
Hcls1hematopoietic cell specific Lyn substrate 10.703
Actr2ARP2 actin-related protein 2 homolog (yeast)0.688
Pard3par-3 (partitioning defective 3) homolog (C. elegans)0.668
ArhgdibRho, GDP dissociation inhibitor (GDI) beta0.665
Prkcbprotein kinase C, beta0.651
Wipf1WAS/WASL interacting protein family, member 10.637
Cfl1cofilin 1, non-muscle0.618
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.610
Csrp1cysteine and glycine-rich protein 10.598
Map4k1mitogen-activated protein kinase kinase kinase kinase 10.587
RictorRPTOR independent companion of MTOR, complex 20.572
Arrb2arrestin, beta 20.569
Arhgap1Rho GTPase activating protein 10.556
Ptpreprotein tyrosine phosphatase, receptor type, E0.544
WasWiskott-Aldrich syndrome homolog (human)0.516
SrcRous sarcoma oncogene0.511
Alox5aparachidonate 5-lipoxygenase activating protein0.501
Laptm5lysosomal-associated protein transmembrane 50.501
CblCasitas B-lineage lymphoma0.501
Sh3gl2SH3-domain GRB2-like 20.499
Ptk2PTK2 protein tyrosine kinase 20.477
Sh3kbp1SH3-domain kinase binding protein 10.468
Dbnldrebrin-like0.468
Tmsb4xthymosin, beta 4, X chromosome0.455
Tagln2transgelin 20.453
NsfN-ethylmaleimide sensitive fusion protein0.449
Hif1ahypoxia inducible factor 1, alpha subunit0.418
Iqgap1IQ motif containing GTPase activating protein 10.414
LynYamaguchi sarcoma viral (v-yes-1) oncogene homolog0.407
Shisa5shisa homolog 5 (Xenopus laevis)0.404
Gnb1guanine nucleotide binding protein (G protein), beta 10.402
Ptprcprotein tyrosine phosphatase, receptor type, C0.397
Bcl10B-cell leukemia/lymphoma 100.397
Cdh2cadherin 20.392
Slit3slit homolog 3 (Drosophila)0.360
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.360
Zap70zeta-chain (TCR) associated protein kinase0.357
Nckap1NCK-associated protein 10.356
Plcg2phospholipase C, gamma 20.343
Cotl1coactosin-like 1 (Dictyostelium)0.339
FybFYN binding protein0.333
Gnb2guanine nucleotide binding protein (G protein), beta 20.293
Inainternexin neuronal intermediate filament protein, alpha0.292
ArhgdiaRho GDP dissociation inhibitor (GDI) alpha0.272
Coro1acoronin, actin binding protein 1A0.270
Robo1roundabout homolog 1 (Drosophila)0.268
Clic1chloride intracellular channel 10.267
Myh9myosin, heavy polypeptide 9, non-muscle0.266
Rhogras homolog gene family, member G0.262
Tpm4tropomyosin 40.255
Ywhahtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.242
Efnb1ephrin B10.242
Vclvinculin0.240
Actn1actinin, alpha 10.237
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.230
Aim2absent in melanoma 20.227
Asap1ArfGAP with SH# domain, ankyrin repeat and PH domain10.227
Trpv2transient receptor potential cation channel, subfamily V, member 20.226
Actn2actinin alpha 20.220
Khdrbs1KH domain containing, RNA binding, signal transduction associated 10.219
Lrrk2leucine-rich repeat kinase 20.218
Gbp5guanylate binding protein 50.214
Caskcalcium/calmodulin-dependent serine protein kinase (MAGUK family)0.213
Pstpip1proline-serine-threonine phosphatase-interacting protein 10.211
Mobkl1bMOB1, Mps One Binder kinase activator-like 1B (yeast)0.211
Capn1calpain 10.210
Mtpnmyotrophin0.204
Epb4.1l2erythrocyte protein band 4.1-like 20.203
Arpc2actin related protein 2/3 complex, subunit 20.197
Fgd1FYVE, RhoGEF and PH domain containing 10.191
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
chicchickadee0.982
Arp66BActin-related protein 66B0.911
twftwinfilin0.826
katanin-60katanin 600.748
cpacapping protein alpha0.699
Rac1CG2248 gene product from transcript CG2248-RA0.676
Cdc42CG12530 gene product from transcript CG12530-RA0.658
trctricornered0.634
flwflapwing0.619
Rho1CG8416 gene product from transcript CG8416-RB0.617
mbcmyoblast city0.610
RalaRas-related protein0.530
cpbcapping protein beta0.524
Vrp1Verprolin 10.524
Arf51FADP ribosylation factor 51F0.494
p120ctnAdherens junction protein p1200.476
uspultraspiracle0.467
Arc-p34CG10954 gene product from transcript CG10954-RA0.457
BicDBicaudal D0.455
enaenabled0.441
eghegghead0.432
par-6CG5884 gene product from transcript CG5884-RA0.423
cindrCIN85 and CD2AP orthologue0.417
par-1CG8201 gene product from transcript CG8201-RA0.414
slssallimus0.382
Akt1CG4006 gene product from transcript CG4006-RA0.373
PakPAK-kinase0.372
S6kRPS6-p70-protein kinase0.371
eglegalitarian0.368
Dcr-2Dicer-20.361
HemHEM-protein0.356
bifbifocal0.355
bazbazooka0.349
zipzipper0.327
Mob2CG11711 gene product from transcript CG11711-RC0.319
spasspastin0.312
Pi3K92ECG4141 gene product from transcript CG4141-RB0.310
roboroundabout0.264
CortactinCG3637 gene product from transcript CG3637-RA0.263
rokRho-kinase0.258
WASpCG1520 gene product from transcript CG1520-RA0.248
Rab5Rab-protein 50.244
snssticks and stones0.217
Actnalpha actinin0.195
ctaconcertina0.189
SosSon of sevenless0.177
ChcClathrin heavy chain0.158
PrmParamyosin0.157
giggigas0.154
Rab11Rab-protein 110.149
DlicDynein light intermediate chain0.146
AbiAbelson interacting protein0.142
CG8578CG8578 gene product from transcript CG8578-RA0.141
spirspire0.138
Arp14DActin-related protein 14D0.136
howheld out wings0.134
Ptp69DProtein tyrosine phosphatase 69D0.128
didumdilute class unconventional myosin0.125
Mlc2Myosin light chain 20.120
CG32556CG32556 gene product from transcript CG32556-RB0.118
msnmisshapen0.118
Pak3CG14895 gene product from transcript CG14895-RA0.111
Btk29ABtk family kinase at 29A0.107
G-oalpha47AG protein oalpha 47A0.106
Liprin-alphaCG11199 gene product from transcript CG11199-RB0.102
Zasp66Z band alternatively spliced PDZ-motif protein 660.100
MtlMig-2-like0.097
sqhspaghetti squash0.096
Sra-1specifically Rac1-associated protein 10.096
Sop2Suppressor of profilin 20.095
Ced-12CG5336 gene product from transcript CG5336-RA0.095
MicalMolecule interacting with CasL0.093
flrflare0.091
numbCG3779 gene product from transcript CG3779-RB0.090
mysmyospheroid0.087
Cip4CG15015 gene product from transcript CG15015-RA0.086
cnccap-n-collar0.083
LaspCG3849 gene product from transcript CG3849-RB0.078
Zasp52Z band alternatively spliced PDZ-motif protein 520.078
14-3-3zetaCG17870 gene product from transcript CG17870-RB0.078
Mlc-cMyosin light chain cytoplasmic0.075
frafrazzled0.073
snsinged0.073
fzfrizzled0.073
kuzkuzbanian0.072
htshu li tai shao0.072
stanstarry night0.071
JraJun-related antigen0.070
staistathmin0.069
drprdraper0.067
MhcMyosin heavy chain0.067
staustaufen0.064
spzspatzle0.064
ShcSHC-adaptor protein0.064
shotshort stop0.063
Rab6Rab-protein 60.062
laceCG4162 gene product from transcript CG4162-RA0.062
rolsrolling pebbles0.060
RhoGEF2CG9635 gene product from transcript CG9635-RF0.059
coracoracle0.056
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CDC42cell division cycle 42 (GTP binding protein, 25kDa)1.000
GRB2growth factor receptor-bound protein 21.000
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)1.000
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.999
GAS7growth arrest-specific 70.998
FYNFYN oncogene related to SRC, FGR, YES0.991
ACTBactin, beta0.989
IQGAP1IQ motif containing GTPase activating protein 10.985
TPM4tropomyosin 40.962
ACTR2ARP2 actin-related protein 2 homolog (yeast)0.953
BAIAP2BAI1-associated protein 20.944
WASLWiskott-Aldrich syndrome-like0.914
ABI1abl-interactor 10.893
CAP1CAP, adenylate cyclase-associated protein 1 (yeast)0.873
NCKAP1NCK-associated protein 10.859
ACTR3ARP3 actin-related protein 3 homolog (yeast)0.858
ARPC1Bactin related protein 2/3 complex, subunit 1B, 41kDa0.853
NCF2neutrophil cytosolic factor 20.813
ZYXzyxin0.807
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.806
WIPF1WAS/WASL interacting protein family, member 10.804
ARPC5actin related protein 2/3 complex, subunit 5, 16kDa0.793
FLNAfilamin A, alpha0.762
ARPC4actin related protein 2/3 complex, subunit 4, 20kDa0.754
NCK1NCK adaptor protein 10.707
ACTG1actin, gamma 10.701
MYH9myosin, heavy chain 9, non-muscle0.696
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.652
ARFGEF2ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)0.635
PSTPIP1proline-serine-threonine phosphatase interacting protein 10.606
CTTNcortactin0.603
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.597
DAAM1dishevelled associated activator of morphogenesis 10.592
VAV1vav 1 guanine nucleotide exchange factor0.590
LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.560
CCR5chemokine (C-C motif) receptor 50.530
FASLGFas ligand (TNF superfamily, member 6)0.486
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.481
FMR1fragile X mental retardation 10.472
ARPC2actin related protein 2/3 complex, subunit 2, 34kDa0.470
SH2D4ASH2 domain containing 4A0.462
PDLIM7PDZ and LIM domain 7 (enigma)0.434
TRIP10thyroid hormone receptor interactor 100.431
NCF1neutrophil cytosolic factor 10.420
ARPC3actin related protein 2/3 complex, subunit 3, 21kDa0.379
RAB1ARAB1A, member RAS oncogene family0.375
VASPvasodilator-stimulated phosphoprotein0.368
EPS8epidermal growth factor receptor pathway substrate 80.359
ITSN1intersectin 1 (SH3 domain protein)0.345
WDR1WD repeat domain 10.313
SPRR2Asmall proline-rich protein 2A0.313
CAPNS1calpain, small subunit 10.307
PARD6Gpar-6 partitioning defective 6 homolog gamma (C. elegans)0.286
ACTN1actinin, alpha 10.277
FNBP1Lformin binding protein 1-like0.273
PRKCAprotein kinase C, alpha0.268
FGRGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.260
HCKhemopoietic cell kinase0.256
SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)0.254
PAK4p21 protein (Cdc42/Rac)-activated kinase 40.250
VCLvinculin0.248
MOBKL1BMOB1, Mps One Binder kinase activator-like 1B (yeast)0.240
FKBP1AFK506 binding protein 1A, 12kDa0.234
PRKAR2Aprotein kinase, cAMP-dependent, regulatory, type II, alpha0.228
ADAM19ADAM metallopeptidase domain 190.225
CAPZBcapping protein (actin filament) muscle Z-line, beta0.213
MYPNmyopalladin0.203
TNK2tyrosine kinase, non-receptor, 20.203
CORO1Ccoronin, actin binding protein, 1C0.201
CCL5chemokine (C-C motif) ligand 50.197
ARFIP2ADP-ribosylation factor interacting protein 20.188
NCKIPSDNCK interacting protein with SH3 domain0.181
TTNtitin0.181
CCR7chemokine (C-C motif) receptor 70.180
PACSIN2protein kinase C and casein kinase substrate in neurons 20.157
FNBP1formin binding protein 10.155
RNF126ring finger protein 1260.153
PRR5proline rich 5 (renal)0.141
PICALMphosphatidylinositol binding clathrin assembly protein0.139
SH3KBP1SH3-domain kinase binding protein 10.138
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.136
TJP1tight junction protein 1 (zona occludens 1)0.130
PACSIN1protein kinase C and casein kinase substrate in neurons 10.129
HTThuntingtin0.128
CYFIP2cytoplasmic FMR1 interacting protein 20.125
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.120
ROD1ROD1 regulator of differentiation 1 (S. pombe)0.120
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.119
BCAR1breast cancer anti-estrogen resistance 10.118
COTL1coactosin-like 1 (Dictyostelium)0.118
RHOUras homolog gene family, member U0.117
SOS1son of sevenless homolog 1 (Drosophila)0.116
YES1v-yes-1 Yamaguchi sarcoma viral oncogene homolog 10.115
CCL4chemokine (C-C motif) ligand 40.114
WASF1WAS protein family, member 10.108
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 10.108
RIPK3receptor-interacting serine-threonine kinase 30.107
CNN2calponin 20.106
C3orf15chromosome 3 open reading frame 150.105
BLNKB-cell linker0.105
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Cap1CAP, adenylate cyclase-associated protein 1 (yeast)0.573
Efhd2EF-hand domain family, member D20.341
Pfn1profilin 10.231
Actr3ARP3 actin-related protein 3 homolog (yeast)0.215
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.192
Arpc2actin related protein 2/3 complex, subunit 20.149
Arf6ADP-ribosylation factor 60.143
Rhoaras homolog gene family, member A0.125
Mapre1microtubule-associated protein, RP/EB family, member 10.109
Myh9myosin, heavy chain 9, non-muscle0.096
Tpm3tropomyosin 3, gamma0.094
Wdr1WD repeat domain 10.085
Rap1bRAP1B, member of RAS oncogene family0.066
Srisorcin0.061
Actbactin, beta0.059
Fkbp1aFK506 binding protein 1a0.059
Arpc1bactin related protein 2/3 complex, subunit 1B0.057
Sirpasignal-regulatory protein alpha0.050
Dstndestrin0.045
Cttncortactin0.044
Plekpleckstrin0.040
Tubb5tubulin, beta 50.038
Taglntransgelin0.038
Ripk3receptor-interacting serine-threonine kinase 30.032
Stk17bserine/threonine kinase 17b0.032
Mtpnmyotrophin0.032
Gnb2guanine nucleotide binding protein (G protein), beta polypeptide 20.029
Ptmaprothymosin alpha0.026
Acta2smooth muscle alpha-actin0.025
S100a10S100 calcium binding protein A100.024
Cd37CD37 molecule0.024
Tmed2transmembrane emp24 domain trafficking protein 20.023
Myo1gmyosin IG0.023
Gnai3guanine nucleotide binding protein (G protein), alpha inhibiting 30.022
Tagln2transgelin 20.021
Sdcbpsyndecan binding protein0.019
Hk1hexokinase 10.019
Arpc5actin related protein 2/3 complex, subunit 50.019
Rac1ras-related C3 botulinum toxin substrate 10.019
Pafah1b2platelet-activating factor acetylhydrolase, isoform 1b, subunit 20.018
Pak2p21 protein (Cdc42/Rac)-activated kinase 20.017
Cd83CD83 molecule0.017
Iqgap1IQ motif containing GTPase activating protein 10.017
Cskc-src tyrosine kinase0.016
Myl9myosin, light chain 9, regulatory0.016
Ets1v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)0.016
Fmnl1formin-like 10.015
Ptprcprotein tyrosine phosphatase, receptor type, C0.015
Map2k1mitogen activated protein kinase kinase 10.015
Coro1acoronin, actin binding protein 1A0.014
Tpm4tropomyosin 40.014
Mobkl2aMOB1, Mps One Binder kinase activator-like 2A (yeast)0.014
Coro1bcoronin, actin-binding protein, 1B0.014
Cd44Cd44 molecule0.014
Clic1chloride intracellular channel 10.014
Rassf5Ras association (RalGDS/AF-6) domain family member 50.013
Arhgap25Rho GTPase activating protein 250.012
Anxa2annexin A20.012
Lcp1lymphocyte cytosolic protein 10.012
Emp1epithelial membrane protein 10.012
Ralbv-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)0.012
Ptpn18protein tyrosine phosphatase, non-receptor type 180.011
Usf1upstream transcription factor 10.011
Ptpn6protein tyrosine phosphatase, non-receptor type 60.011
Cfl1cofilin 1, non-muscle0.011
Actn1actinin, alpha 10.011
Cnn3calponin 3, acidic0.010
Stxbp5syntaxin binding protein 5 (tomosyn)0.010
Nedd4neural precursor cell expressed, developmentally down-regulated 40.010
Testestis derived transcript0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
MYO5Myo5p0.995
CAP2Cap2p0.874
ABP1Abp1p0.805
RVS167Rvs167p0.711
ARC15Arc15p0.705
SRV2Srv2p0.703
ARC40Arc40p0.666
LSB1Lsb1p0.452
ARC35Arc35p0.428
BBC1Bbc1p0.386
BZZ1Bzz1p0.383
ARP2Arp2p0.356
ARC19Arc19p0.345
ACT1Act1p0.342
SAC6Sac6p0.272
BOI1Boi1p0.251
ARP3Arp3p0.203
PFY1Pfy1p0.165
CAP1Cap1p0.142
COF1Cof1p0.111
BCK1Bck1p0.090
RHO1Rho1p0.085
AIP1Aip1p0.076
ARC18Arc18p0.066
AVO1Avo1p0.066
CDC24Cdc24p0.054
SLA2Sla2p0.049
GYL1Gyl1p0.049
CDC55Cdc55p0.040
RDI1Rdi1p0.034
LAS17Las17p0.032
VRP1Vrp1p0.030
BEM3Bem3p0.028
YPK1Ypk1p0.027
TWF1Twf1p0.025
SPA2Spa2p0.024
ZDS1Zds1p0.023
UBP7Ubp7p0.022
FIR1Fir1p0.022
STE5Ste5p0.022
CMD1Cmd1p0.022
SCP1Scp1p0.021
AIM21Aim21p0.020
PPH21Pph21p0.019
TPM1Tpm1p0.019
BMH1Bmh1p0.019
TCO89Tco89p0.019
YMR315Whypothetical protein0.019
CPR5Cpr5p0.017
YER134Chypothetical protein0.017
ARP10Arp10p0.017
YPR1Ypr1p0.017
YLR264C-Ahypothetical protein0.016
SRD1Srd1p0.016
KOG1Kog1p0.016
YAR068Whypothetical protein0.016
SRO77Sro77p0.016
HXT3Hxt3p0.015
YLR162Whypothetical protein0.015
ADH2Adh2p0.015
YOL038C-Ahypothetical protein0.015
SAR1Sar1p0.015
LEU2Leu2p0.014
ZDS2Zds2p0.014
YSC84Ysc84p0.014
SPL2Spl2p0.014
APP1App1p0.014
TSC11Tsc11p0.013
FMN1Fmn1p0.013
MER1Mer1p0.013
YIR035Chypothetical protein0.013
YBR096Whypothetical protein0.013
UPS3Ups3p0.013
YAR066Whypothetical protein0.012
BSP1Bsp1p0.012
HPF1Hpf1p0.012
YNR064Chypothetical protein0.012
CUE4Cue4p0.012
ARO10Aro10p0.012
YGL015Chypothetical protein0.012
SGE1Sge1p0.012
YTA6Yta6p0.012
PRS2Prs2p0.012
ZPS1Zps1p0.012
YLR042Chypothetical protein0.012
PKH3Pkh3p0.011
URA3Ura3p0.011
CUP1-1Cup1-1p0.011
ARG8Arg8p0.011
YPR157Whypothetical protein0.011
AUA1Aua1p0.011
SPR6Spr6p0.011
YIL151Chypothetical protein0.011
ATP6Atp6p0.011
CHA1Cha1p0.011
YBR013Chypothetical protein0.011
OPT2Opt2p0.011
CPD1Cpd1p0.011
TYE7Tye7p0.011
BIT61Bit61p0.011