The network for 'positive regulation of macrophage activation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of macrophage activation

Any process that stimulates, induces or increases the rate of macrophage activation.

NameDescriptionProbabilityFunc Analog Organism
Csf2rb2colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)0.999
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.989
Stat6signal transducer and activator of transcription 60.975
Il1rl1interleukin 1 receptor-like 10.913
Stat3signal transducer and activator of transcription 30.828
FasFas (TNF receptor superfamily member 6)0.760
Ifnginterferon gamma0.669
Il6interleukin 60.583
Il2interleukin 20.532
Hspa9heat shock protein 90.477
Selpselectin, platelet0.465
Tnfrsf9tumor necrosis factor receptor superfamily, member 90.421
Il1r1interleukin 1 receptor, type I0.326
Il13interleukin 130.313
Osmroncostatin M receptor0.266
Il4rainterleukin 4 receptor, alpha0.265
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.264
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.230
Il1binterleukin 1 beta0.222
Il1rninterleukin 1 receptor antagonist0.212
Serpina3nserine (or cysteine) peptidase inhibitor, clade A, member 3N0.188
Lrg1leucine-rich alpha-2-glycoprotein 10.185
Dact1dapper homolog 1, antagonist of beta-catenin (xenopus)0.148
Slfn4schlafen 40.129
Il33interleukin 330.122
Myd88myeloid differentiation primary response gene 880.114
Il18rapinterleukin 18 receptor accessory protein0.112
Mmp8matrix metallopeptidase 80.110
Il1r2interleukin 1 receptor, type II0.104
Ccl2chemokine (C-C motif) ligand 20.096
Adam8a disintegrin and metallopeptidase domain 80.095
Lcn2lipocalin 20.093
Klrk1killer cell lectin-like receptor subfamily K, member 10.091
Nlrp3NLR family, pyrin domain containing 30.090
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.089
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.088
Plaurplasminogen activator, urokinase receptor0.085
Il17rainterleukin 17 receptor A0.080
Hsp90b1heat shock protein 90, beta (Grp94), member 10.078
C5ar1complement component 5a receptor 10.077
Loxlysyl oxidase0.076
1100001G20RikRIKEN cDNA 1100001G20 gene0.075
Chi3l3chitinase 3-like 30.061
LitafLPS-induced TN factor0.058
F10coagulation factor X0.056
Map3k14mitogen-activated protein kinase kinase kinase 140.054
Cd14CD14 antigen0.053
Clec4dC-type lectin domain family 4, member d0.052
Ccr1chemokine (C-C motif) receptor 10.052
Map3k8mitogen-activated protein kinase kinase kinase 80.052
Runx1runt related transcription factor 10.051
Tnftumor necrosis factor0.047
Saa3serum amyloid A 30.047
C1racomplement component 1, r subcomponent A0.046
Cxcl2chemokine (C-X-C motif) ligand 20.046
Slpisecretory leukocyte peptidase inhibitor0.045
Tlr4toll-like receptor 40.044
Il1rapinterleukin 1 receptor accessory protein0.044
Cxcl1chemokine (C-X-C motif) ligand 10.044
Cd80CD80 antigen0.043
Ccr2chemokine (C-C motif) receptor 20.043
Col1a1collagen, type I, alpha 10.042
Bcl3B-cell leukemia/lymphoma 30.042
LynYamaguchi sarcoma viral (v-yes-1) oncogene homolog0.042
Tmem176atransmembrane protein 176A0.041
Slc10a6solute carrier family 10 (sodium/bile acid cotransporter family), member 60.039
Olr1oxidized low density lipoprotein (lectin-like) receptor 10.038
Steap4STEAP family member 40.036
Relreticuloendotheliosis oncogene0.036
S100a8S100 calcium binding protein A8 (calgranulin A)0.035
S100a9S100 calcium binding protein A9 (calgranulin B)0.034
Clec4eC-type lectin domain family 4, member e0.033
Mmp3matrix metallopeptidase 30.033
Ror2receptor tyrosine kinase-like orphan receptor 20.032
Cxcr2chemokine (C-X-C motif) receptor 20.031
Hdchistidine decarboxylase0.031
Mdm2transformed mouse 3T3 cell double minute 20.031
Il13ra2interleukin 13 receptor, alpha 20.030
Trp63transformation related protein 630.030
Cxcl5chemokine (C-X-C motif) ligand 50.029
Il6stinterleukin 6 signal transducer0.028
Ghrgrowth hormone receptor0.025
Il13ra1interleukin 13 receptor, alpha 10.025
Rag1recombination activating gene 10.024
Il4interleukin 40.024
Ccl17chemokine (C-C motif) ligand 170.023
Cd40lgCD40 ligand0.023
Lifleukemia inhibitory factor0.021
ItkIL2-inducible T-cell kinase0.021
Soat2sterol O-acyltransferase 20.019
Clca1chloride channel calcium activated 10.018
Fgd3FYVE, RhoGEF and PH domain containing 30.018
Tolliptoll interacting protein0.018
Dnaja3DnaJ (Hsp40) homolog, subfamily A, member 30.018
Inpp5dinositol polyphosphate-5-phosphatase D0.017
Ccl7chemokine (C-C motif) ligand 70.017
Serpine1serine (or cysteine) peptidase inhibitor, clade E, member 10.017
Arid5aAT rich interactive domain 5A (MRF1-like)0.016
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism