The network for 'regulation of macrophage activation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of macrophage activation

Any process that modulates the frequency or rate of macrophage activation.

NameDescriptionProbabilityFunc Analog Organism
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.970
Il1rl1interleukin 1 receptor-like 10.945
Csf2rb2colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)0.913
Stat6signal transducer and activator of transcription 60.752
Il1r1interleukin 1 receptor, type I0.537
Il4rainterleukin 4 receptor, alpha0.514
Ghrgrowth hormone receptor0.480
Hspa9heat shock protein 90.363
U46068cDNA sequence U460680.210
Atxn1ataxin 10.186
Il1rapinterleukin 1 receptor accessory protein0.183
Hsp90b1heat shock protein 90, beta (Grp94), member 10.181
Chi3l3chitinase 3-like 30.167
Klrk1killer cell lectin-like receptor subfamily K, member 10.158
F7coagulation factor VII0.151
S100a8S100 calcium binding protein A8 (calgranulin A)0.142
Mmp8matrix metallopeptidase 80.141
Selpselectin, platelet0.128
Itih4inter alpha-trypsin inhibitor, heavy chain 40.119
2210010C04RikRIKEN cDNA 2210010C04 gene0.117
Cxcr2chemokine (C-X-C motif) receptor 20.107
Il33interleukin 330.095
Pigrpolymeric immunoglobulin receptor0.091
Il18rapinterleukin 18 receptor accessory protein0.081
Il6interleukin 60.077
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.074
MefvMediterranean fever0.074
Dact1dapper homolog 1, antagonist of beta-catenin (xenopus)0.074
C5ar1complement component 5a receptor 10.072
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.071
Il1rninterleukin 1 receptor antagonist0.071
Stat3signal transducer and activator of transcription 30.068
Slpisecretory leukocyte peptidase inhibitor0.067
Cd44CD44 antigen0.065
Il1binterleukin 1 beta0.062
Adam8a disintegrin and metallopeptidase domain 80.059
Sntb1syntrophin, basic 10.055
Soat2sterol O-acyltransferase 20.054
Muc13mucin 13, epithelial transmembrane0.049
Osmroncostatin M receptor0.049
Steap4STEAP family member 40.049
Map3k14mitogen-activated protein kinase kinase kinase 140.048
Ccl17chemokine (C-C motif) ligand 170.047
Map3k8mitogen-activated protein kinase kinase kinase 80.046
Sftpdsurfactant associated protein D0.046
Clec4eC-type lectin domain family 4, member e0.046
Tnfrsf9tumor necrosis factor receptor superfamily, member 90.043
Zbtb16zinc finger and BTB domain containing 160.042
Ptf1apancreas specific transcription factor, 1a0.042
Htr3a5-hydroxytryptamine (serotonin) receptor 3A0.039
Csf2colony stimulating factor 2 (granulocyte-macrophage)0.038
Il17ainterleukin 17A0.036
Reg3gregenerating islet-derived 3 gamma0.036
Krt4keratin 40.036
Clca1chloride channel calcium activated 10.036
Tff1trefoil factor 10.036
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.036
Slc10a6solute carrier family 10 (sodium/bile acid cotransporter family), member 60.035
Lrg1leucine-rich alpha-2-glycoprotein 10.035
Cxcl2chemokine (C-X-C motif) ligand 20.034
Bdkrb1bradykinin receptor, beta 10.033
Hba-a2hemoglobin alpha, adult chain 20.033
Msr1macrophage scavenger receptor 10.032
Tnfrsf4tumor necrosis factor receptor superfamily, member 40.032
Mdm2transformed mouse 3T3 cell double minute 20.032
Cxcl1chemokine (C-X-C motif) ligand 10.031
Plaurplasminogen activator, urokinase receptor0.031
Krtap5-1keratin associated protein 5-10.031
Gpr97G protein-coupled receptor 970.031
Slfn4schlafen 40.031
Thrbthyroid hormone receptor beta0.031
Trp63transformation related protein 630.030
Pcsk5proprotein convertase subtilisin/kexin type 50.030
Vhlvon Hippel-Lindau tumor suppressor0.030
Serpina3nserine (or cysteine) peptidase inhibitor, clade A, member 3N0.029
Runx1runt related transcription factor 10.029
Inhbainhibin beta-A0.028
Rgs16regulator of G-protein signaling 160.027
1100001G20RikRIKEN cDNA 1100001G20 gene0.027
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.027
Gpr132G protein-coupled receptor 1320.026
Itih2inter-alpha trypsin inhibitor, heavy chain 20.025
Krt71keratin 710.025
Tolliptoll interacting protein0.024
Hivep3human immunodeficiency virus type I enhancer binding protein 30.023
Ifnginterferon gamma0.023
Nphp4nephronophthisis 4 (juvenile) homolog (human)0.023
Ahraryl-hydrocarbon receptor0.023
Gcgrglucagon receptor0.023
Ceacam1carcinoembryonic antigen-related cell adhesion molecule 10.023
F10coagulation factor X0.023
Ins1insulin I0.022
C4bcomplement component 4B (Childo blood group)0.022
Masp2mannan-binding lectin serine peptidase 20.022
Ceacam2carcinoembryonic antigen-related cell adhesion molecule 20.022
C80012expressed sequence C800120.022
Reg1regenerating islet-derived 10.021
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.019
Hspa8heat shock protein 80.012
LOC681996similar to AHA1, activator of heat shock 90kDa protein ATPase homolog 10.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism