The network for 'positive regulation of immune system process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of immune system process

Any process that activates or increases the frequency, rate, or extent of an immune system process.

NameDescriptionProbabilityFunc Analog Organism
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
mpxmyeloid-specific peroxidase0.941
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.651
c3bcomplement component c3b0.597
tal1T-cell acute lymphocytic leukemia 10.469
efnb2aephrin B2a0.456
shhasonic hedgehog a0.405
gata1aGATA binding protein 1a0.392
foxb1.2forkhead box B1.20.364
ets1av-ets erythroblastosis virus E26 oncogene homolog 1a0.238
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.214
epas1bendothelial PAS domain protein 1b0.204
bmp2bbone morphogenetic protein 2b0.192
nanos3nanos homolog 30.168
fzd7afrizzled homolog 7a0.156
fgfr3fibroblast growth factor receptor 30.149
erbb3bv-erb-b2 erythroblastic leukemia viral oncogene homolog 3b0.146
junjun proto-oncogene0.137
runx1runt-related transcription factor 10.133
mmp9matrix metalloproteinase 90.132
tgfb3transforming growth factor, beta 30.125
socs3asuppressor of cytokine signaling 3a0.121
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.117
LOC566708FL cytokine receptor-like0.117
dnmt4DNA (cytosine-5-)-methyltransferase 40.110
kitakit receptor a0.110
gpr126G protein-coupled receptor 1260.104
ergv-ets erythroblastosis virus E26 oncogene like (avian)0.103
ip6k2inositol hexaphosphate kinase 20.101
bmperBMP binding endothelial regulator0.098
sfrp1asecreted frizzled-related protein 1a0.096
tlr9toll-like receptor 90.095
grnagranulin a0.093
c1qccomplement component 1, q subcomponent, C chain0.093
acvr2aactivin receptor IIa0.091
rargaretinoic acid receptor gamma a0.091
tnfsf10l2tumor necrosis factor (ligand) superfamily, member 10 like 20.090
runx2arunt-related transcription factor 2a0.089
col12a1collagen, type XII, alpha 10.089
tlr3toll-like receptor 30.074
ef1aelongation factor 1-alpha0.074
timp2btissue inhibitor of metalloproteinase 2b0.074
nfkbiaanuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a0.074
pax5paired box gene 50.074
cyp3a65cytochrome P450, family 3, subfamily A, polypeptide 650.071
fcho2FCH domain only 20.071
stc1lstanniocalcin 1, like0.069
il6rinterleukin 6 receptor0.068
rhbgRhesus blood group, B glycoprotein0.066
nr2f5nuclear receptor subfamily 2, group F, member 50.065
mmp2matrix metalloproteinase 20.065
stat5.1signal transducer and activator of transcription 5.10.064
tnfatumor necrosis factor a (TNF superfamily, member 2)0.064
coro1acoronin, actin binding protein, 1A0.063
nrg1neuregulin 10.063
LOC100000934hypothetical protein LOC1000009340.062
fn1fibronectin 10.061
trpm7transient receptor potential cation channel, subfamily M, member 70.060
stat1bsignal transducer and activator of transcription 1b0.057
pcdh18bprotocadherin 18b0.056
egr2bearly growth response 2b0.055
calcrlacalcitonin receptor-like a0.055
alkanaplastic lymphoma kinase (Ki-1)0.054
gadd45bagrowth arrest and DNA-damage-inducible, beta a0.054
entpd1ectonucleoside triphosphate diphosphohydrolase 10.053
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.052
caspacaspase a0.050
foxd3forkhead box D30.049
kdrlkinase insert domain receptor like0.049
nadl1.2neural adhesion molecule L1.20.049
wnt8awingless-type MMTV integration site family, member 8a0.048
kpna3karyopherin (importin) alpha 30.048
postnperiostin, osteoblast specific factor0.048
fzd7bfrizzled homolog 7b0.048
hbbe1.1hemoglobin beta embryonic-1.10.047
c1qbcomplement component 1, q subcomponent, B chain0.047
ripk2receptor-interacting serine-threonine kinase 20.046
tnfbtumor necrosis factor b (TNF superfamily, member 2)0.046
mmp14amatrix metalloproteinase 14a (membrane-inserted)0.046
cx43connexin 430.046
pdcd2programmed cell death 20.045
wasbWiskott-Aldrich syndrome (eczema-thrombocytopenia) b0.044
dll4delta-like 4 (Drosophila)0.044
krml2.2Kreisler (mouse) maf-related leucine zipper homolog 2.20.044
alcamaactivated leukocyte cell adhesion molecule a0.044
ifnphi1interferon phi 10.044
scinlbscinderin like b0.043
socs1suppressor of cytokine signaling 10.043
smad9MAD homolog 9 (Drosophila)0.043
axin2axin 2 (conductin, axil)0.042
ntrk3bneurotrophic tyrosine kinase, receptor, type 3b0.042
ptger4bprostaglandin E receptor 4 (subtype EP4) b0.042
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
mbcmyoblast city0.883
PGRP-LCPeptidoglycan recognition protein LC0.802
DptBDiptericin B0.779
Spn27ASerpin 27A0.606
drkdownstream of receptor kinase0.350
Mpk2CG5475 gene product from transcript CG5475-RB0.330
S6kRPS6-p70-protein kinase0.310
IrcImmune-regulated catalase0.297
PGRP-SAPeptidoglycan recognition protein SA0.269
grassGram-positive Specific Serine protease0.264
PvrPDGF- and VEGF-receptor related0.245
PGRP-SDCG7496 gene product from transcript CG7496-RA0.224
SPESpatzle-Processing Enzyme0.224
stcksteamer duck0.201
JIL-1CG6297 gene product from transcript CG6297-RA0.185
EgfrEpidermal growth factor receptor0.180
Mekk1CG7717 gene product from transcript CG7717-RB0.180
numbCG3779 gene product from transcript CG3779-RB0.179
Rac2CG8556 gene product from transcript CG8556-RA0.175
CG6361CG6361 gene product from transcript CG6361-RA0.173
norpAno receptor potential A0.145
SnooSno oncogene0.144
Myo31DFMyosin 31DF0.140
Myd88CG2078 gene product from transcript CG2078-RA0.134
MP1Melanization Protease 10.124
bratbrain tumor0.120
Idgf2Imaginal disc growth factor 20.118
Sin3ACG8815 gene product from transcript CG8815-RC0.112
p120ctnAdherens junction protein p1200.111
Spn28DSerpin 28D0.109
Sp7Serine protease 70.105
CecCCecropin C0.105
DreddDeath related ced-3/Nedd2-like protein0.104
NijANinjurin A0.103
ird5immune response deficient 50.101
Tab2TAK1-associated binding protein 20.091
rev7CG2948 gene product from transcript CG2948-RA0.089
TimpTissue inhibitor of metalloproteases0.086
cicubitus interruptus0.085
Pi3K92ECG4141 gene product from transcript CG4141-RB0.084
modSPmodular serine protease0.084
HcfHost cell factor0.083
Ptp69DProtein tyrosine phosphatase 69D0.081
InRInsulin-like receptor0.080
DadDaughters against dpp0.079
E2f2E2F transcription factor 20.077
Gyc76CGuanylyl cyclase at 76C0.076
ird1immune response deficient 10.076
Mkp3Mitogen-activated protein kinase phosphatase 30.072
Dcp-1Death caspase-10.071
bowlbrother of odd with entrails limited0.069
HsfHeat shock factor0.067
CG8155CG8155 gene product from transcript CG8155-RA0.066
Spn1Serine protease inhibitor 10.066
Toll-7CG8595 gene product from transcript CG8595-RA0.065
CG18666CG18666 gene product from transcript CG18666-RA0.065
IndyI'm not dead yet0.062
Hr39Hormone receptor-like in 390.062
CG15083CG15083 gene product from transcript CG15083-RA0.062
DuoxDual oxidase0.062
CG4168CG4168 gene product from transcript CG4168-RA0.062
MTF-1Metal response element-binding Transcription Factor-10.062
CG9631CG9631 gene product from transcript CG9631-RA0.061
EphrinCG1862 gene product from transcript CG1862-RA0.061
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)1.000
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma1.000
GRB2growth factor receptor-bound protein 21.000
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.998
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.998
BIRC3baculoviral IAP repeat containing 30.997
SHC1SHC (Src homology 2 domain containing) transforming protein 10.996
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.995
LCKlymphocyte-specific protein tyrosine kinase0.994
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.994
TNFAIP3tumor necrosis factor, alpha-induced protein 30.993
ESR1estrogen receptor 10.988
CREBBPCREB binding protein0.987
PTPN1protein tyrosine phosphatase, non-receptor type 10.985
IRAK1interleukin-1 receptor-associated kinase 10.985
TRAF6TNF receptor-associated factor 60.985
NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.985
CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)0.984
CD3ECD3e molecule, epsilon (CD3-TCR complex)0.981
CCR7chemokine (C-C motif) receptor 70.977
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.973
HCKhemopoietic cell kinase0.971
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.971
TRAF1TNF receptor-associated factor 10.968
FGRGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.960
SOCS3suppressor of cytokine signaling 30.954
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.953
STAT1signal transducer and activator of transcription 1, 91kDa0.950
EGFRepidermal growth factor receptor0.947
CCR1chemokine (C-C motif) receptor 10.946
ICAM1intercellular adhesion molecule 10.943
CCR5chemokine (C-C motif) receptor 50.943
IL1Binterleukin 1, beta0.942
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.940
CASP8caspase 8, apoptosis-related cysteine peptidase0.938
ZAP70zeta-chain (TCR) associated protein kinase 70kDa0.935
TNIP2TNFAIP3 interacting protein 20.935
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.934
SYKspleen tyrosine kinase0.926
FASLGFas ligand (TNF superfamily, member 6)0.923
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.921
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.921
FGFR2fibroblast growth factor receptor 20.918
XIAPX-linked inhibitor of apoptosis0.906
PMLpromyelocytic leukemia0.906
CD86CD86 molecule0.904
CXCL9chemokine (C-X-C motif) ligand 90.903
RELv-rel reticuloendotheliosis viral oncogene homolog (avian)0.900
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.897
IRF4interferon regulatory factor 40.897
LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.892
PTK2PTK2 protein tyrosine kinase 20.891
CCL5chemokine (C-C motif) ligand 50.886
MAP3K7mitogen-activated protein kinase kinase kinase 70.886
IL2RBinterleukin 2 receptor, beta0.878
CCR2chemokine (C-C motif) receptor 20.877
CXCL10chemokine (C-X-C motif) ligand 100.873
MYD88myeloid differentiation primary response gene (88)0.869
CD80CD80 molecule0.867
JUNjun proto-oncogene0.862
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.859
CARD11caspase recruitment domain family, member 110.854
IL8interleukin 80.851
CD74CD74 molecule, major histocompatibility complex, class II invariant chain0.847
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.847
HLA-DRAmajor histocompatibility complex, class II, DR alpha0.846
PLCG1phospholipase C, gamma 10.842
ABI1abl-interactor 10.838
RELBv-rel reticuloendotheliosis viral oncogene homolog B0.830
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.826
CD84CD84 molecule0.822
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.821
PSMB9proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)0.819
CXCL2chemokine (C-X-C motif) ligand 20.814
CCL22chemokine (C-C motif) ligand 220.810
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.806
AXLAXL receptor tyrosine kinase0.794
IL10interleukin 100.793
IL4Rinterleukin 4 receptor0.792
CASP3caspase 3, apoptosis-related cysteine peptidase0.788
TEKTEK tyrosine kinase, endothelial0.787
MALT1mucosa associated lymphoid tissue lymphoma translocation gene 10.787
IL6interleukin 6 (interferon, beta 2)0.784
CCL2chemokine (C-C motif) ligand 20.781
VCAM1vascular cell adhesion molecule 10.781
BCL2B-cell CLL/lymphoma 20.774
PTPRCprotein tyrosine phosphatase, receptor type, C0.771
SLAMF1signaling lymphocytic activation molecule family member 10.767
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.763
IL10RAinterleukin 10 receptor, alpha0.760
FGAfibrinogen alpha chain0.759
TNFtumor necrosis factor0.752
KLRD1killer cell lectin-like receptor subfamily D, member 10.746
CAV1caveolin 1, caveolae protein, 22kDa0.745
TAP1transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)0.745
CCL3chemokine (C-C motif) ligand 30.745
VAV1vav 1 guanine nucleotide exchange factor0.743
IL1R1interleukin 1 receptor, type I0.742
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Cd37CD37 molecule0.926
St8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 40.755
Il1binterleukin 1 beta0.683
Calcrlcalcitonin receptor-like0.653
Klrd1killer cell lectin-like receptor, subfamily D, member 10.636
Csf1colony stimulating factor 1 (macrophage)0.620
Ccr5chemokine (C-C motif) receptor 50.619
Casp1caspase 10.618
Il2rginterleukin 2 receptor, gamma0.600
Kcnj8potassium inwardly-rectifying channel, subfamily J, member 80.584
Cd38CD38 molecule0.571
Ccl4chemokine (C-C motif) ligand 40.538
Il6interleukin 60.513
RT1-BaRT1 class II, locus Ba0.510
Fcgr3aFc fragment of IgG, low affinity IIIa, receptor0.462
Timp3TIMP metallopeptidase inhibitor 30.452
Cd4Cd4 molecule0.451
Tgfbr2transforming growth factor, beta receptor II0.447
Plauplasminogen activator, urokinase0.434
Cxcl10chemokine (C-X-C motif) ligand 100.420
Cxcr4chemokine (C-X-C motif) receptor 40.402
Ptafrplatelet-activating factor receptor0.365
RT1-EC2RT1 class Ib, locus EC20.361
Cfbcomplement factor B0.360
Cd14CD14 molecule0.354
LOC100360403ATP-binding cassette, sub-family C, member 9-like0.349
Ly86lymphocyte antigen 860.344
Cybbcytochrome b-245, beta polypeptide0.335
Cd5Cd5 molecule0.324
Prf1perforin 1 (pore forming protein)0.321
Sellselectin L0.316
Irf5interferon regulatory factor 50.309
Lst1leukocyte specific transcript 10.305
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.304
Vav1vav 1 guanine nucleotide exchange factor0.292
Alox5aparachidonate 5-lipoxygenase activating protein0.276
Hckhemopoietic cell kinase0.268
Dchs1dachsous 1 (Drosophila)0.260
Mmp12matrix metallopeptidase 120.254
Cpa3carboxypeptidase A3, mast cell0.252
Dnase1l3deoxyribonuclease 1-like 30.251
Ptprcprotein tyrosine phosphatase, receptor type, C0.250
Gzmkgranzyme K0.246
Ms4a2membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)0.236
Vcam1vascular cell adhesion molecule 10.223
Ciitaclass II, major histocompatibility complex, transactivator0.220
Fgfr2fibroblast growth factor receptor 20.219
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.214
Itpr2inositol 1,4,5-triphosphate receptor, type 20.212
Socs3suppressor of cytokine signaling 30.202
Cxcl6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.200
Zcwpw1zinc finger, CW-type with PWWP domain 10.198
Folr2folate receptor 2 (fetal)0.198
Cmklr1chemokine-like receptor 10.194
Ccl3chemokine (C-C motif) ligand 30.193
Cd247Cd247 molecule0.192
Cd68Cd68 molecule0.190
Clec9aC-type lectin domain family 9, member a0.189
Serpina3nserine (or cysteine) peptidase inhibitor, clade A, member 3N0.187
Psmb9proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)0.182
Pla2g4aphospholipase A2, group IVA (cytosolic, calcium-dependent)0.178
P2ry14purinergic receptor P2Y, G-protein coupled, 140.177
Jak1Janus kinase 10.175
FaslgFas ligand (TNF superfamily, member 6)0.175
RGD1559588similar to cell surface receptor FDFACT0.174
Il9rinterleukin 9 receptor0.174
RT1-DaRT1 class II, locus Da0.173
Arandrogen receptor0.172
P2ry6pyrimidinergic receptor P2Y, G-protein coupled, 60.172
Il7rinterleukin 7 receptor0.172
Tnftumor necrosis factor (TNF superfamily, member 2)0.171
MrgprfMAS-related GPR, member F0.170
Icam1intercellular adhesion molecule 10.168
S1pr2sphingosine-1-phosphate receptor 20.167
Sirpasignal-regulatory protein alpha0.161
RGD1559748similar to Palate lung and nasal carcinoma-like protein precursor (Tongue plunc-like protein)0.158
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.157
Cd53Cd53 molecule0.155
Jak2Janus kinase 20.152
Olfml2bolfactomedin-like 2B0.152
Pecam1platelet/endothelial cell adhesion molecule 10.151
Slco2b1solute carrier organic anion transporter family, member 2b10.149
Map3k1mitogen activated protein kinase kinase kinase 10.149
Ctsecathepsin E0.149
Il2rbinterleukin 2 receptor, beta0.147
Kmokynurenine 3-monooxygenase (kynurenine 3-hydroxylase)0.146
Arhgap25Rho GTPase activating protein 250.144
Ccl7chemokine (C-C motif) ligand 70.143
F2rl2coagulation factor II (thrombin) receptor-like 20.142
Cd74Cd74 molecule, major histocompatibility complex, class II invariant chain0.141
Atf3activating transcription factor 30.139
Mca32mast cell antigen 320.138
Gja4gap junction protein, alpha 40.138
Cd2Cd2 molecule0.138
Cxcr5chemokine (C-X-C motif) receptor 50.137
Csf3rcolony stimulating factor 3 receptor (granulocyte)0.136
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism