The network for 'acyl coa biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

acyl coa biosynthetic process

The chemical reactions and pathways resulting in the formation of acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group.

NameDescriptionProbabilityFunc Analog Organism
Ndufs1NADH dehydrogenase (ubiquinone) Fe-S protein 10.968
Hibch3-hydroxyisobutyryl-Coenzyme A hydrolase0.283
Atp5a1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 10.281
Idh3aisocitrate dehydrogenase 3 (NAD+) alpha0.280
Mvdmevalonate (diphospho) decarboxylase0.163
Uqcrc2ubiquinol cytochrome c reductase core protein 20.155
Cscitrate synthase0.147
Fasnfatty acid synthase0.113
Vdac2voltage-dependent anion channel 20.112
Gfm1G elongation factor, mitochondrial 10.109
Plin4perilipin 40.085
Ywhahtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.083
Ndrg2N-myc downstream regulated gene 20.072
Pdha1pyruvate dehydrogenase E1 alpha 10.070
Aifm1apoptosis-inducing factor, mitochondrion-associated 10.069
Slc27a1solute carrier family 27 (fatty acid transporter), member 10.061
AclyATP citrate lyase0.054
Tmx2thioredoxin-related transmembrane protein 20.051
Gypaglycophorin A0.049
Thrspthyroid hormone responsive SPOT14 homolog (Rattus)0.044
Hadhbhydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit0.043
Pcxpyruvate carboxylase0.041
Scd1stearoyl-Coenzyme A desaturase 10.040
Lsslanosterol synthase0.039
Suclg1succinate-CoA ligase, GDP-forming, alpha subunit0.039
Hba-a2hemoglobin alpha, adult chain 20.037
Fh1fumarate hydratase 10.036
Macrod1MACRO domain containing 10.036
Adck3aarF domain containing kinase 30.034
Acat2acetyl-Coenzyme A acetyltransferase 20.032
Eef1a2eukaryotic translation elongation factor 1 alpha 20.028
Tmem70transmembrane protein 700.028
Iars2isoleucine-tRNA synthetase 2, mitochondrial0.028
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.027
Cycscytochrome c, somatic0.027
Alas2aminolevulinic acid synthase 2, erythroid0.027
Sdhdsuccinate dehydrogenase complex, subunit D, integral membrane protein0.025
Epn1epsin 10.025
Ppp1r1aprotein phosphatase 1, regulatory (inhibitor) subunit 1A0.024
Liaslipoic acid synthetase0.024
Beta-shemoglobin subunit beta-1-like0.023
Acsl1acyl-CoA synthetase long-chain family member 10.023
Sqlesqualene epoxidase0.022
Cideacell death-inducing DNA fragmentation factor, alpha subunit-like effector A0.022
Uqcrbubiquinol-cytochrome c reductase binding protein0.022
Pink1PTEN induced putative kinase 10.021
Fabp4fatty acid binding protein 4, adipocyte0.021
Pdhxpyruvate dehydrogenase complex, component X0.020
Dhcr77-dehydrocholesterol reductase0.020
Hibadh3-hydroxyisobutyrate dehydrogenase0.020
Acadmacyl-Coenzyme A dehydrogenase, medium chain0.020
Tff1trefoil factor 10.020
Lrpprcleucine-rich PPR-motif containing0.020
Etfdhelectron transferring flavoprotein, dehydrogenase0.019
Lrrk2leucine-rich repeat kinase 20.019
Echdc1enoyl Coenzyme A hydratase domain containing 10.018
Lpin1lipin 10.017
Immtinner membrane protein, mitochondrial0.017
Acad11acyl-Coenzyme A dehydrogenase family, member 110.017
Isca1iron-sulfur cluster assembly 1 homolog (S. cerevisiae)0.017
Afg3l2AFG3(ATPase family gene 3)-like 2 (yeast)0.017
Dgat2diacylglycerol O-acyltransferase 20.017
Slc25a23solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 230.016
Cfdcomplement factor D (adipsin)0.016
Entpd5ectonucleoside triphosphate diphosphohydrolase 50.016
Sod2superoxide dismutase 2, mitochondrial0.016
Fxyd1FXYD domain-containing ion transport regulator 10.016
Uqcrfs1ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 10.015
Chrna7cholinergic receptor, nicotinic, alpha polypeptide 70.015
Gpd1glycerol-3-phosphate dehydrogenase 1 (soluble)0.015
Mtfp1mitochondrial fission process 10.015
Ephx2epoxide hydrolase 2, cytoplasmic0.015
Ghitmgrowth hormone inducible transmembrane protein0.015
Elovl6ELOVL family member 6, elongation of long chain fatty acids (yeast)0.014
Bnip3BCL2/adenovirus E1B interacting protein 30.014
Grsf1G-rich RNA sequence binding factor 10.014
Ndufa10NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 100.014
Pex7peroxisomal biogenesis factor 70.014
Aco2aconitase 2, mitochondrial0.014
Pmpcbpeptidase (mitochondrial processing) beta0.014
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.014
Mlycdmalonyl-CoA decarboxylase0.014
Gpamglycerol-3-phosphate acyltransferase, mitochondrial0.013
Snap25synaptosomal-associated protein 250.013
Cox8bcytochrome c oxidase, subunit VIIIb0.013
Elmod3ELMO/CED-12 domain containing 30.013
Haghhydroxyacyl glutathione hydrolase0.013
Hmgcs13-hydroxy-3-methylglutaryl-Coenzyme A synthase 10.013
Ahspalpha hemoglobin stabilizing protein0.013
Cplx1complexin 10.013
Slc4a1solute carrier family 4 (anion exchanger), member 10.012
Echdc3enoyl Coenzyme A hydratase domain containing 30.012
Ndufab1NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 10.012
Stmn2stathmin-like 20.012
Aatkapoptosis-associated tyrosine kinase0.012
Sema4fsema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain0.011
Adipoqadiponectin, C1Q and collagen domain containing0.011
Chchd3coiled-coil-helix-coiled-coil-helix domain containing 30.011
Dlddihydrolipoamide dehydrogenase0.011
Atp5bATP synthase, H+ transporting mitochondrial F1 complex, beta subunit0.011
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
ndufv1NADH dehydrogenase (ubiquinone) flavoprotein 10.567
cyc1cytochrome c-10.091
aco2aconitase 2, mitochondrial0.083
dlatdihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)0.072
sucla2succinate-CoA ligase, ADP-forming, beta subunit0.046
dlstdihydrolipoamide S-succinyltransferase0.027
nrarpanotch-regulated ankyrin repeat protein a0.024
sdhasuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.021
nntnicotinamide nucleotide transhydrogenase0.013
sdhbsuccinate dehydrogenase complex, subunit B, iron sulfur (Ip)0.011
tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.010
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
CG7430CG7430 gene product from transcript CG7430-RA0.341
blwbellwether0.224
CG8036CG8036 gene product from transcript CG8036-RB0.070
PyKPyruvate kinase0.069
CG6439CG6439 gene product from transcript CG6439-RA0.055
CG11876CG11876 gene product from transcript CG11876-RA0.042
CG1640CG1640 gene product from transcript CG1640-RB0.040
CG5214CG5214 gene product from transcript CG5214-RA0.040
skapskpA associated protein0.035
CG7920CG7920 gene product from transcript CG7920-RA0.030
ND75NADH:ubiquinone reductase 75kD subunit precursor0.029
AconAconitase0.029
SdhASuccinate dehydrogenase A0.022
CG17896CG17896 gene product from transcript CG17896-RB0.020
CG10639CG10639 gene product from transcript CG10639-RA0.020
CG3731CG3731 gene product from transcript CG3731-RA0.018
HLH106Helix loop helix protein 1060.017
MdhCG5889 gene product from transcript CG5889-RC0.015
CG11198CG11198 gene product from transcript CG11198-RB0.014
l(1)G0156lethal (1) G01560.012
IdhIsocitrate dehydrogenase0.012
PgmPhosphogluconate mutase0.010
vigvasa intronic gene0.010
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PDHXpyruvate dehydrogenase complex, component X1.000
DLATdihydrolipoamide S-acetyltransferase0.999
PDHBpyruvate dehydrogenase (lipoamide) beta0.997
PDHA1pyruvate dehydrogenase (lipoamide) alpha 10.480
NDUFS1NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)0.192
CYCScytochrome c, somatic0.178
IDH3Aisocitrate dehydrogenase 3 (NAD+) alpha0.097
PFDN1prefoldin subunit 10.087
DLDdihydrolipoamide dehydrogenase0.054
AIFM1apoptosis-inducing factor, mitochondrion-associated, 10.052
ANXA7annexin A70.047
GOT1glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)0.039
SNCAIPsynuclein, alpha interacting protein0.032
MAPTmicrotubule-associated protein tau0.020
FHfumarate hydratase0.015
SGK3serum/glucocorticoid regulated kinase family, member 30.015
SUCLA2succinate-CoA ligase, ADP-forming, beta subunit0.015
MRPL35mitochondrial ribosomal protein L350.011
UQCRC2ubiquinol-cytochrome c reductase core protein II0.011
FDX1ferredoxin 10.010
DOCK7dedicator of cytokinesis 70.010
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Ndufs1NADH dehydrogenase (ubiquinone) Fe-S protein 10.821
Pdha1pyruvate dehydrogenase (lipoamide) alpha 10.760
Dlddihydrolipoamide dehydrogenase0.653
Pdhbpyruvate dehydrogenase (lipoamide) beta0.219
Uqcrc2ubiquinol cytochrome c reductase core protein 20.166
Sdhasuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.104
Ube2bubiquitin-conjugating enzyme E2B (RAD6 homolog, S. cerevisiae)0.081
Dlatdihydrolipoamide S-acetyltransferase0.058
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.049
Sod2superoxide dismutase 2, mitochondrial0.043
Aldh6a1aldehyde dehydrogenase 6 family, member A10.043
Me1malic enzyme 1, NADP(+)-dependent, cytosolic0.037
Cycscytochrome c, somatic0.034
Ppp1cbprotein phosphatase 1, catalytic subunit, beta isoform0.032
Ndufaf4NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 40.032
Hspa9heat shock protein 90.030
RGD1565095similar to hypothetical protein MGC521100.027
Etfaelectron-transfer-flavoprotein, alpha polypeptide0.024
Hibadh3-hydroxyisobutyrate dehydrogenase0.023
Fdft1farnesyl diphosphate farnesyl transferase 10.022
Adkadenosine kinase0.018
Aldh2aldehyde dehydrogenase 2 family (mitochondrial)0.018
Sucla2succinate-CoA ligase, ADP-forming, beta subunit0.018
Pfkmphosphofructokinase, muscle0.017
Pink1PTEN induced putative kinase 10.017
Pdhxpyruvate dehydrogenase complex, component X0.017
Tfrctransferrin receptor0.015
Bpnt13'(2'), 5'-bisphosphate nucleotidase 10.014
Eif4a2eukaryotic translation initiation factor 4A, isoform 20.014
Capza2capping protein (actin filament) muscle Z-line, alpha 20.012
Oxct13-oxoacid CoA transferase 10.012
Dlstdihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)0.011
Pgk1phosphoglycerate kinase 10.011
Isoc1isochorismatase domain containing 10.011
ClpxClpX caseinolytic peptidase X homolog (E. coli)0.011
Pxmp2peroxisomal membrane protein 20.010
Adhfe1alcohol dehydrogenase, iron containing, 10.010
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
LAT1Lat1p0.032
CYM1Cym1p0.023
LPD1Lpd1p0.016
PDB1Pdb1p0.013