The network for 'protein n linked glycosylation via asparagine' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

protein n linked glycosylation via asparagine

The glycosylation of protein via the N4 atom of peptidyl-asparagine forming N4-glycosyl-L-asparagine; the most common form is N-acetylglucosaminyl asparagine; N-acetylgalactosaminyl asparagine and N4 glucosyl asparagine also occur. This modification typically occurs in extracellular peptides with an N-X-(ST) motif. Partial modification has been observed to occur with cysteine, rather than serine or threonine, in the third position; secondary structure features are important, and proline in the second or fourth positions inhibits modification.

NameDescriptionProbabilityFunc Analog Organism
Hspa5heat shock protein 50.691
Manfmesencephalic astrocyte-derived neurotrophic factor0.088
Dnajb11DnaJ (Hsp40) homolog, subfamily B, member 110.074
Creld2cysteine-rich with EGF-like domains 20.053
H47histocompatibility 470.039
Pdia3protein disulfide isomerase associated 30.031
Rpn2ribophorin II0.025
Hsp90b1heat shock protein 90, beta (Grp94), member 10.024
Serp1stress-associated endoplasmic reticulum protein 10.022
Spcs2signal peptidase complex subunit 2 homolog (S. cerevisiae)0.021
Slc35b1solute carrier family 35, member B10.021
Dnajc3DnaJ (Hsp40) homolog, subfamily C, member 30.021
Pdia6protein disulfide isomerase associated 60.020
Nsfl1cNSFL1 (p97) cofactor (p47)0.020
Slc30a5solute carrier family 30 (zinc transporter), member 50.017
Sec61a1Sec61 alpha 1 subunit (S. cerevisiae)0.017
Sec23bSEC23B (S. cerevisiae)0.016
Tram1translocating chain-associating membrane protein 10.013
Spcs3signal peptidase complex subunit 3 homolog (S. cerevisiae)0.011
Surf4surfeit gene 40.010
Psen1presenilin 10.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
DERL1Der1-like domain family, member 10.918
AMFRautocrine motility factor receptor0.847
ERN1endoplasmic reticulum to nucleus signaling 10.847
PDIA6protein disulfide isomerase family A, member 60.697
SELSselenoprotein S0.444
HERPUD1homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 10.176
UBE4Bubiquitination factor E4B (UFD2 homolog, yeast)0.143
HYOU1hypoxia up-regulated 10.087
SSR3signal sequence receptor, gamma (translocon-associated protein gamma)0.078
UBE2J1ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)0.054
USP7ubiquitin specific peptidase 7 (herpes virus-associated)0.048
SPCS3signal peptidase complex subunit 3 homolog (S. cerevisiae)0.045
NSFL1CNSFL1 (p97) cofactor (p47)0.040
VCPvalosin containing protein0.040
AUP1ancient ubiquitous protein 10.037
TMED2transmembrane emp24 domain trafficking protein 20.028
DERL2Der1-like domain family, member 20.024
NPLOC4nuclear protein localization 4 homolog (S. cerevisiae)0.018
FAF2Fas associated factor family member 20.017
UBE2D2ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)0.017
SYVN1synovial apoptosis inhibitor 1, synoviolin0.017
AP1G1adaptor-related protein complex 1, gamma 1 subunit0.016
EAPPE2F-associated phosphoprotein0.015
MGAT2mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase0.015
TP53tumor protein p530.014
DR1down-regulator of transcription 1, TBP-binding (negative cofactor 2)0.014
SEL1Lsel-1 suppressor of lin-12-like (C. elegans)0.011
DAD1defender against cell death 10.011
TRIM27tripartite motif containing 270.011
CNNM3cyclin M30.011
TRIM43tripartite motif containing 430.011
TRAM1translocation associated membrane protein 10.011
ATN1atrophin 10.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism