The network for 'regulation of oxidoreductase activity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of oxidoreductase activity

Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

NameDescriptionProbabilityFunc Analog Organism
Leprleptin receptor0.432
Ptenphosphatase and tensin homolog0.336
Nos3nitric oxide synthase 3, endothelial cell0.319
Itgb1integrin beta 1 (fibronectin receptor beta)0.179
Lyz2lysozyme 20.138
Trp53transformation related protein 530.123
Tgfbr1transforming growth factor, beta receptor I0.104
Tnftumor necrosis factor0.102
Ctnnb1catenin (cadherin associated protein), beta 10.089
Tgfbr2transforming growth factor, beta receptor II0.085
Casp4caspase 4, apoptosis-related cysteine peptidase0.073
FasFas (TNF receptor superfamily member 6)0.061
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.060
Cd44CD44 antigen0.059
Tlr4toll-like receptor 40.059
Notch2Notch gene homolog 2 (Drosophila)0.053
Vegfavascular endothelial growth factor A0.050
SrcRous sarcoma oncogene0.049
Ppargperoxisome proliferator activated receptor gamma0.048
Ric8resistance to inhibitors of cholinesterase 8 homolog (C. elegans)0.048
PycardPYD and CARD domain containing0.047
Apoeapolipoprotein E0.047
Map3k8mitogen-activated protein kinase kinase kinase 80.042
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.042
Casp1caspase 10.042
Rxraretinoid X receptor alpha0.042
Tlr2toll-like receptor 20.042
Tgfb1transforming growth factor, beta 10.041
Traf6TNF receptor-associated factor 60.040
Ptgs2prostaglandin-endoperoxide synthase 20.037
Plauplasminogen activator, urokinase0.035
Il1r1interleukin 1 receptor, type I0.035
Ppargc1aperoxisome proliferative activated receptor, gamma, coactivator 1 alpha0.033
Tnfaip3tumor necrosis factor, alpha-induced protein 30.033
Wt1Wilms tumor 1 homolog0.031
Map3k14mitogen-activated protein kinase kinase kinase 140.031
Hif1ahypoxia inducible factor 1, alpha subunit0.030
Agtr1aangiotensin II receptor, type 1a0.029
Pcdh12protocadherin 120.028
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.028
Smad4MAD homolog 4 (Drosophila)0.026
Nos1nitric oxide synthase 1, neuronal0.024
Ywhahtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.024
Agtangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.024
Nos2nitric oxide synthase 2, inducible0.023
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.023
Loxlysyl oxidase0.023
Csf1colony stimulating factor 1 (macrophage)0.022
Bdkrb2bradykinin receptor, beta 20.022
Cdkn1bcyclin-dependent kinase inhibitor 1B0.021
Agtrapangiotensin II, type I receptor-associated protein0.021
Ptrfpolymerase I and transcript release factor0.020
Casp8caspase 80.020
Acvrl1activin A receptor, type II-like 10.020
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.020
Nfe2l2nuclear factor, erythroid derived 2, like 20.019
Ren1renin 1 structural0.018
Hsd17b10hydroxysteroid (17-beta) dehydrogenase 100.018
Ifnginterferon gamma0.018
Ldlrlow density lipoprotein receptor0.017
Bcar1breast cancer anti-estrogen resistance 10.016
Cd40CD40 antigen0.016
Nr0b2nuclear receptor subfamily 0, group B, member 20.016
Egfrepidermal growth factor receptor0.016
Insrinsulin receptor0.015
Efemp2epidermal growth factor-containing fibulin-like extracellular matrix protein 20.015
Npy1rneuropeptide Y receptor Y10.015
Apoa1apolipoprotein A-I0.015
Myd88myeloid differentiation primary response gene 880.015
Col1a1collagen, type I, alpha 10.015
Lrp1low density lipoprotein receptor-related protein 10.015
Dll4delta-like 4 (Drosophila)0.014
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.014
Dmddystrophin, muscular dystrophy0.014
Cav1caveolin 1, caveolae protein0.014
Ptpn11protein tyrosine phosphatase, non-receptor type 110.014
Clcn5chloride channel 50.014
Fbn1fibrillin 10.013
Plin1perilipin 10.013
Grhprglyoxylate reductase/hydroxypyruvate reductase0.013
Gna11guanine nucleotide binding protein, alpha 110.013
Il1ainterleukin 1 alpha0.013
En1engrailed 10.012
Nr3c1nuclear receptor subfamily 3, group C, member 10.012
Rbpjlrecombination signal binding protein for immunoglobulin kappa J region-like0.012
Smad2MAD homolog 2 (Drosophila)0.012
Lifleukemia inhibitory factor0.012
Megf8multiple EGF-like-domains 80.012
Ces1dcarboxylesterase 1D0.012
Adcy4adenylate cyclase 40.012
Rag1recombination activating gene 10.012
Cyp4a14cytochrome P450, family 4, subfamily a, polypeptide 140.012
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.012
Esr1estrogen receptor 1 (alpha)0.011
Il22interleukin 220.011
Gm3776predicted gene 37760.011
Tnfrsf11atumor necrosis factor receptor superfamily, member 11a0.011
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.011
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha0.994
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.988
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.956
ESR1estrogen receptor 10.917
MAPTmicrotubule-associated protein tau0.865
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.667
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.623
HNF4Ahepatocyte nuclear factor 4, alpha0.606
BCL3B-cell CLL/lymphoma 30.599
RARAretinoic acid receptor, alpha0.546
NFKBIEnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon0.538
NCF1neutrophil cytosolic factor 10.523
IL1R1interleukin 1 receptor, type I0.499
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.466
RELBv-rel reticuloendotheliosis viral oncogene homolog B0.440
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.440
APOEapolipoprotein E0.438
TRAF1TNF receptor-associated factor 10.391
NCOR2nuclear receptor corepressor 20.326
RELv-rel reticuloendotheliosis viral oncogene homolog (avian)0.326
BCAR1breast cancer anti-estrogen resistance 10.301
IL1RAPinterleukin 1 receptor accessory protein0.253
TNFRSF1Atumor necrosis factor receptor superfamily, member 1A0.249
TRADDTNFRSF1A-associated via death domain0.223
PPP5Cprotein phosphatase 5, catalytic subunit0.222
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.217
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.206
BIRC3baculoviral IAP repeat containing 30.202
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.193
PPARGperoxisome proliferator-activated receptor gamma0.192
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.192
PDZD11PDZ domain containing 110.175
TNFRSF1Btumor necrosis factor receptor superfamily, member 1B0.160
CTNND1catenin (cadherin-associated protein), delta 10.159
CALCAcalcitonin-related polypeptide alpha0.157
ITGB1BP3integrin beta 1 binding protein 30.148
NOXA1NADPH oxidase activator 10.148
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.147
SH2D1ASH2 domain containing 1A0.143
MPDZmultiple PDZ domain protein0.141
APOC1apolipoprotein C-I0.128
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.128
DLG2discs, large homolog 2 (Drosophila)0.126
MAGI3membrane associated guanylate kinase, WW and PDZ domain containing 30.125
MYLK2myosin light chain kinase 20.119
PTENphosphatase and tensin homolog0.115
APOA1apolipoprotein A-I0.113
DSG2desmoglein 20.111
IL1R2interleukin 1 receptor, type II0.103
IFNGinterferon, gamma0.102
PICK1protein interacting with PRKCA 10.097
SPRR2Asmall proline-rich protein 2A0.095
ESRRGestrogen-related receptor gamma0.093
CDC37cell division cycle 37 homolog (S. cerevisiae)0.090
TGFB1transforming growth factor, beta 10.089
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.088
MUC1mucin 1, cell surface associated0.086
IL1RNinterleukin 1 receptor antagonist0.083
IGF2Rinsulin-like growth factor 2 receptor0.082
APCadenomatous polyposis coli0.081
ANKS1Bankyrin repeat and sterile alpha motif domain containing 1B0.080
FYNFYN oncogene related to SRC, FGR, YES0.079
MAP3K8mitogen-activated protein kinase kinase kinase 80.079
TNIP2TNFAIP3 interacting protein 20.074
CAV2caveolin 20.073
CCL20chemokine (C-C motif) ligand 200.073
RIPK2receptor-interacting serine-threonine kinase 20.072
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.072
IGF1Rinsulin-like growth factor 1 receptor0.071
NFKBIZnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta0.070
HRhairless homolog (mouse)0.070
IL2RBinterleukin 2 receptor, beta0.068
FABP4fatty acid binding protein 4, adipocyte0.067
TGFAtransforming growth factor, alpha0.066
CDCP1CUB domain containing protein 10.065
CALM1calmodulin 1 (phosphorylase kinase, delta)0.064
BABAM1BRISC and BRCA1 A complex member 10.062
ARRDC3arrestin domain containing 30.061
CCL4chemokine (C-C motif) ligand 40.059
FADDFas (TNFRSF6)-associated via death domain0.056
HDAC1histone deacetylase 10.055
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.055
CXCR6chemokine (C-X-C motif) receptor 60.054
TRAF2TNF receptor-associated factor 20.052
MATKmegakaryocyte-associated tyrosine kinase0.052
TNFRSF9tumor necrosis factor receptor superfamily, member 90.051
PRKCAprotein kinase C, alpha0.050
BCL10B-cell CLL/lymphoma 100.050
APOC3apolipoprotein C-III0.050
SPTBN1spectrin, beta, non-erythrocytic 10.048
IL1Binterleukin 1, beta0.047
DDR2discoidin domain receptor tyrosine kinase 20.047
PRF1perforin 1 (pore forming protein)0.044
LRP6low density lipoprotein receptor-related protein 60.044
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.109
Ccnd3cyclin D30.083
Ptp4a2protein tyrosine phosphatase 4a20.071
Fkbp1aFK506 binding protein 1a0.037
CdonCdon homolog (mouse)0.032
Gnb2guanine nucleotide binding protein (G protein), beta polypeptide 20.032
Arf5ADP-ribosylation factor 50.031
Ywhahtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.031
RGD1307752similar to RIKEN cDNA 1110008F130.030
Mapk3mitogen activated protein kinase 30.030
Sub1SUB1 homolog (S. cerevisiae)0.028
Il6interleukin 60.028
Fshbfollicle stimulating hormone, beta polypeptide0.027
Cdc34cell division cycle 34 homolog (S. cerevisiae)0.024
Metmet proto-oncogene0.023
St6galnac3ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 30.023
Cftrcystic fibrosis transmembrane conductance regulator homolog (human)0.022
Cyp2a2cytochrome P450, family 2, subfamily a, polypeptide 20.022
Atp2b1ATPase, Ca++ transporting, plasma membrane 10.022
Unc5bunc-5 homolog B (C. elegans)0.021
Tbxa2rthromboxane A2 receptor0.020
Csrp1cysteine and glycine-rich protein 10.018
Ap2s1adaptor-related protein complex 2, sigma 1 subunit0.018
Cyp4a3cytochrome P450, family 4, subfamily a, polypeptide 30.018
Mertkc-mer proto-oncogene tyrosine kinase0.018
Plcg2phospholipase C, gamma 20.018
Clcn3chloride channel 30.018
Cdh6cadherin 60.017
Calm2calmodulin 20.017
Acvr1cactivin A receptor, type IC0.017
Actr2ARP2 actin-related protein 2 homolog (yeast)0.017
Cdkn2bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.017
Mapk6mitogen-activated protein kinase 60.017
Htr2b5-hydroxytryptamine (serotonin) receptor 2B0.017
Fcer2Fc fragment of IgE, low affinity II, receptor for (CD23)0.016
Xcl1chemokine (C motif) ligand 10.016
Efhd2EF-hand domain family, member D20.016
Edn2endothelin 20.015
Il8rainterleukin 8 receptor, alpha0.015
Hoxa4homeo box A40.015
Uhmk1U2AF homology motif (UHM) kinase 10.015
Il1binterleukin 1 beta0.015
BadBCL2-associated agonist of cell death0.015
Krt8keratin 80.015
Col4a4collagen, type IV, alpha 40.015
Tmem120atransmembrane protein 120A0.015
Ccl20chemokine (C-C motif) ligand 200.015
Tgfb2transforming growth factor, beta 20.015
Nrp2neuropilin 20.014
Mmdmonocyte to macrophage differentiation-associated0.014
Pcbd1pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha0.014
BokBCL2-related ovarian killer0.014
Adrbk1adrenergic, beta, receptor kinase 10.014
Mgst2microsomal glutathione S-transferase 20.014
Coro1bcoronin, actin-binding protein, 1B0.014
Six1SIX homeobox 10.014
Actn4actinin alpha 40.014
Parm1prostate androgen-regulated mucin-like protein 10.014
Rasa1RAS p21 protein activator (GTPase activating protein) 10.014
Il2rbinterleukin 2 receptor, beta0.014
Ccl4chemokine (C-C motif) ligand 40.014
Kcnj1potassium inwardly-rectifying channel, subfamily J, member 10.013
Hk1hexokinase 10.013
Atp6v0cATPase, H+ transporting, lysosomal V0 subunit C0.013
Gstm1glutathione S-transferase mu 10.013
Atxn3ataxin 30.013
Grhprglyoxylate reductase/hydroxypyruvate reductase0.013
Slc15a2solute carrier family 15 (H+/peptide transporter), member 20.013
Foxe3forkhead box E30.013
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.013
Mrgprx3MAS-related GPR, member X30.013
F2rl1coagulation factor II (thrombin) receptor-like 10.013
Ghrhgrowth hormone releasing hormone0.012
Ptpn14protein tyrosine phosphatase, non-receptor type 140.012
Prelid1PRELI domain containing 10.012
Ap1s1adaptor-related protein complex 1, sigma 1 subunit0.012
Calm1calmodulin 10.012
Grem1gremlin 1, cysteine knot superfamily, homolog (Xenopus laevis)0.012
Ctrcchymotrypsin C (caldecrin)0.012
Cd86CD86 molecule0.012
Krt4keratin 40.012
Ntf4neurotrophin 40.012
Tmem205transmembrane protein 2050.012
Serpina3nserine (or cysteine) peptidase inhibitor, clade A, member 3N0.012
Bmp3bone morphogenetic protein 30.011
Slc7a9solute carrier family 7 (cationic amino acid transporter, y+ system), member 90.011
Megf6multiple EGF-like-domains 60.011
Slc22a2solute carrier family 22 (organic cation transporter), member 20.011
Ccnd1cyclin D10.011
Stc1stanniocalcin 10.011
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.011
Foxe1forkhead box E1 (thyroid transcription factor 2)0.011
Glrx5glutaredoxin 50.011
Chrnecholinergic receptor, nicotinic, epsilon0.011
Slc26a2solute carrier family 26 (sulfate transporter), member 20.011
Cd55Cd55 molecule0.011
Tectec protein tyrosine kinase0.010
Cdkn1ccyclin-dependent kinase inhibitor 1C0.010
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism