The network for 'negative regulation of nucleoside metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of nucleoside metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.

NameDescriptionProbabilityFunc Analog Organism
Spry2sprouty homolog 2 (Drosophila)0.707
Spry4sprouty homolog 4 (Drosophila)0.690
Mcm3minichromosome maintenance deficient 3 (S. cerevisiae)0.669
Spry1sprouty homolog 1 (Drosophila)0.501
Lsm2LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)0.443
Mcm5minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)0.422
Srsf9serine/arginine-rich splicing factor 90.364
Neurl1aneuralized homolog 1A (Drosophila)0.174
Cdt1chromatin licensing and DNA replication factor 10.145
Fnip1folliculin interacting protein 10.142
Thoc4THO complex 40.125
Uhrf1ubiquitin-like, containing PHD and RING finger domains, 10.115
Ppp4cprotein phosphatase 4, catalytic subunit0.110
Timelesstimeless homolog (Drosophila)0.109
Ywhahtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.091
Refbp2RNA and export factor binding protein 20.091
Rcc2regulator of chromosome condensation 20.082
Mcm7minichromosome maintenance deficient 7 (S. cerevisiae)0.063
Pfn1profilin 10.055
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.054
Mcm6minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)0.043
Fgfr3fibroblast growth factor receptor 30.043
Siah2seven in absentia 20.039
Prmt1protein arginine N-methyltransferase 10.037
Tmem30atransmembrane protein 30A0.036
Hnrnpabheterogeneous nuclear ribonucleoprotein A/B0.034
Tubb5tubulin, beta 50.034
Mrpl36mitochondrial ribosomal protein L360.033
H2afxH2A histone family, member X0.032
Stim2stromal interaction molecule 20.032
Rfc5replication factor C (activator 1) 50.029
Ptprnprotein tyrosine phosphatase, receptor type, N0.029
Pold1polymerase (DNA directed), delta 1, catalytic subunit0.028
Lig1ligase I, DNA, ATP-dependent0.028
Tomm40translocase of outer mitochondrial membrane 40 homolog (yeast)0.028
Cdk4cyclin-dependent kinase 40.027
Eif4a1eukaryotic translation initiation factor 4A10.026
Arhgef7Rho guanine nucleotide exchange factor (GEF7)0.026
Rcc1regulator of chromosome condensation 10.025
4932438A13RikRIKEN cDNA 4932438A13 gene0.024
Cdc34cell division cycle 34 homolog (S. cerevisiae)0.024
Ptmaprothymosin alpha0.024
Nr2f1nuclear receptor subfamily 2, group F, member 10.023
Dnajb9DnaJ (Hsp40) homolog, subfamily B, member 90.022
Pdpk13-phosphoinositide dependent protein kinase 10.022
Adcy9adenylate cyclase 90.021
Fen1flap structure specific endonuclease 10.019
Axin1axin 10.019
Tnnc1troponin C, cardiac/slow skeletal0.018
Tsc22d2TSC22 domain family, member 20.018
Rad51RAD51 homolog (S. cerevisiae)0.018
Rsl24d1ribosomal L24 domain containing 10.018
Itsn1intersectin 1 (SH3 domain protein 1A)0.018
Dab1disabled homolog 1 (Drosophila)0.017
3110043O21RikRIKEN cDNA 3110043O21 gene0.017
Hivep1human immunodeficiency virus type I enhancer binding protein 10.017
Sult4a1sulfotransferase family 4A, member 10.017
Sos2son of sevenless homolog 2 (Drosophila)0.017
Psmd3proteasome (prosome, macropain) 26S subunit, non-ATPase, 30.016
Pcbp1poly(rC) binding protein 10.016
Cab39calcium binding protein 390.016
E2f1E2F transcription factor 10.016
Rangap1RAN GTPase activating protein 10.015
Rrm2ribonucleotide reductase M20.015
Cdca7cell division cycle associated 70.015
Wdr26WD repeat domain 260.015
Varsvalyl-tRNA synthetase0.015
Gsk3bglycogen synthase kinase 3 beta0.015
Zfand5zinc finger, AN1-type domain 50.015
Golga4golgi autoantigen, golgin subfamily a, 40.015
ArhgdigRho GDP dissociation inhibitor (GDI) gamma0.015
Trappc10trafficking protein particle complex 100.015
Zbtb45zinc finger and BTB domain containing 450.015
Banf1barrier to autointegration factor 10.015
Cks1bCDC28 protein kinase 1b0.014
Kif21akinesin family member 21A0.014
Rnf11ring finger protein 110.014
Lmnb1lamin B10.014
Cdc6cell division cycle 6 homolog (S. cerevisiae)0.014
Ifrd2interferon-related developmental regulator 20.014
Trip11thyroid hormone receptor interactor 110.014
Pdia4protein disulfide isomerase associated 40.013
Grb2growth factor receptor bound protein 20.013
1110008P14RikRIKEN cDNA 1110008P14 gene0.013
Kif1bkinesin family member 1B0.013
Epn2epsin 20.013
Dnajc3DnaJ (Hsp40) homolog, subfamily C, member 30.013
HopxHOP homeobox0.013
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.013
Ssr3signal sequence receptor, gamma0.013
Rb1cc1RB1-inducible coiled-coil 10.012
Dohhdeoxyhypusine hydroxylase/monooxygenase0.012
Hspbp1HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 10.012
Ap2a1adaptor protein complex AP-2, alpha 1 subunit0.012
Mcm2minichromosome maintenance deficient 2 mitotin (S. cerevisiae)0.012
1810013L24RikRIKEN cDNA 1810013L24 gene0.012
Ubtfupstream binding transcription factor, RNA polymerase I0.012
Dlg1discs, large homolog 1 (Drosophila)0.012
Phldb2pleckstrin homology-like domain, family B, member 20.012
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
gpr-2Protein GPR-20.283
gpr-1Protein GPR-10.219
spdl-1Protein SPDL-10.096
ZC434.8Protein ZC434.80.069
ptp-1Protein PTP-10.058
scd-1Protein SCD-10.058
myo-2Protein MYO-20.049
CELE_F14E5.2Protein F14E5.20.049
mrps-15Protein MRPS-150.047
tbb-1Protein TBB-10.043
pme-1Protein PME-10.039
hsp-1Protein HSP-10.037
snr-3Protein SNR-30.028
cye-1Protein CYE-10.027
dao-5Protein DAO-50.022
alg-1Protein ALG-10.022
ani-1Protein ANI-10.019
dnj-16Protein DNJ-160.018
prp-3Protein PRP-30.018
ntl-4Protein NTL-40.018
C18A3.3Protein C18A3.30.018
sax-3Protein SAX-30.016
sym-4Protein SYM-40.016
klp-18Protein KLP-180.016
cyp-31A2Protein CYP-31A20.014
sea-2Protein SEA-20.013
goa-1Protein GOA-10.013
pck-1Protein PCK-10.013
F45H10.2Protein F45H10.20.013
sucg-1Protein SUCG-10.012
aat-5Protein AAT-50.012
Y53C12B.1Protein Y53C12B.10.012
hsp-12.2Protein HSP-12.20.012
ucr-2.3Protein UCR-2.30.012
F26E4.6Protein F26E4.60.011
C53C9.2Protein C53C9.20.011
ptp-3Protein PTP-30.011
tps-1Protein TPS-10.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Ras85DRas oncogene at 85D0.418
EcREcdysone receptor0.047
ovoCG6824 gene product from transcript CG6824-RE0.039
Vps35Vacuolar protein sorting 350.036
Dsp1Dorsal switch protein 10.032
l(2)03709lethal (2) 037090.027
RnpS1RNA-binding protein S10.022
CG9797CG9797 gene product from transcript CG9797-RA0.018
Rpb5CG11979 gene product from transcript CG11979-RA0.018
IncenpInner centromere protein0.017
ftz-f1ftz transcription factor 10.016
CG3353CG3353 gene product from transcript CG3353-RA0.016
EfTuMElongation factor Tu mitochondrial0.016
CG33116CG33116 gene product from transcript CG33116-RA0.015
CG2021CG2021 gene product from transcript CG2021-RA0.015
SetCG4299 gene product from transcript CG4299-RA0.014
IswiImitation SWI0.014
mod(mdg4)modifier of mdg40.014
FK506-bp2FK506-binding protein 20.014
AmunCG2446 gene product from transcript CG2446-RB0.014
U2af38U2 small nuclear riboprotein auxiliary factor 380.013
CycBCyclin B0.013
CG12079CG12079 gene product from transcript CG12079-RA0.012
RecQ4CG7487 gene product from transcript CG7487-RA0.012
MED22Mediator complex subunit 220.012
poloCG12306 gene product from transcript CG12306-RA0.011
Ykt6CG1515 gene product from transcript CG1515-RA0.011
CG15019CG15019 gene product from transcript CG15019-RB0.011
mus209mutagen-sensitive 2090.011
Bx42CG8264 gene product from transcript CG8264-RA0.011
Caf1Chromatin assembly factor 1 subunit0.011
Rpb11CG6840 gene product from transcript CG6840-RA0.011
HopHsp70/Hsp90 organizing protein homolog0.010
CG3621CG3621 gene product from transcript CG3621-RA0.010
Rpn5CG1100 gene product from transcript CG1100-RA0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
TNNC1troponin C type 1 (slow)0.442
CALM1calmodulin 1 (phosphorylase kinase, delta)0.248
ARHGEF11Rho guanine nucleotide exchange factor (GEF) 110.205
SEMA4Asema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A0.145
HAP1huntingtin-associated protein 10.135
MAP3K5mitogen-activated protein kinase kinase kinase 50.100
TRIM63tripartite motif containing 630.071
SNTB2syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)0.071
RND1Rho family GTPase 10.046
MCM5minichromosome maintenance complex component 50.043
TBCDtubulin folding cofactor D0.043
RALAv-ral simian leukemia viral oncogene homolog A (ras related)0.042
LMAN1lectin, mannose-binding, 10.041
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.036
PRMT6protein arginine methyltransferase 60.035
AKT1v-akt murine thymoma viral oncogene homolog 10.034
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.032
TRAM1translocation associated membrane protein 10.032
ARRB1arrestin, beta 10.028
MCM3minichromosome maintenance complex component 30.025
PDE6Dphosphodiesterase 6D, cGMP-specific, rod, delta0.024
MCFD2multiple coagulation factor deficiency 20.021
RALBP1ralA binding protein 10.021
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.021
TUBB2Ctubulin, beta 2C0.020
TFRCtransferrin receptor (p90, CD71)0.020
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 20.019
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.018
WNT5Awingless-type MMTV integration site family, member 5A0.017
WNT3Awingless-type MMTV integration site family, member 3A0.016
HMOX2heme oxygenase (decycling) 20.016
AMOTL1angiomotin like 10.016
MST1Rmacrophage stimulating 1 receptor (c-met-related tyrosine kinase)0.016
DDX39BDEAD (Asp-Glu-Ala-Asp) box polypeptide 39B0.015
TNNI2troponin I type 2 (skeletal, fast)0.015
LRP6low density lipoprotein receptor-related protein 60.014
HDGFhepatoma-derived growth factor0.014
RALBv-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)0.014
NUS1nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)0.014
VKORC1vitamin K epoxide reductase complex, subunit 10.013
ASF1BASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.013
CACNA1Ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.013
TMED9transmembrane emp24 protein transport domain containing 90.012
TMED10transmembrane emp24-like trafficking protein 10 (yeast)0.012
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.012
RPS6KA6ribosomal protein S6 kinase, 90kDa, polypeptide 60.012
SURF4surfeit 40.012
UNC119unc-119 homolog (C. elegans)0.012
TSPAN4tetraspanin 40.012
PEBP4phosphatidylethanolamine-binding protein 40.012
SNF8SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)0.012
GOLT1Bgolgi transport 1B0.012
LMNB2lamin B20.011
TNNI1troponin I type 1 (skeletal, slow)0.011
BBS10Bardet-Biedl syndrome 100.011
SSRP1structure specific recognition protein 10.011
TNNT1troponin T type 1 (skeletal, slow)0.011
SPRY2sprouty homolog 2 (Drosophila)0.010
SDHBsuccinate dehydrogenase complex, subunit B, iron sulfur (Ip)0.010
SPRY1sprouty homolog 1, antagonist of FGF signaling (Drosophila)0.010
ELF5E74-like factor 5 (ets domain transcription factor)0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism