The network for 'retinal cone cell development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

retinal cone cell development

Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision.

NameDescriptionProbabilityFunc Analog Organism
Thrathyroid hormone receptor alpha0.992
Nr2e1nuclear receptor subfamily 2, group E, member 10.977
Tbx5T-box 50.969
Prph2peripherin 20.968
Dclk1doublecortin-like kinase 10.963
Crb2crumbs homolog 2 (Drosophila)0.951
Gucy2dguanylate cyclase 2d0.947
Atxn1ataxin 10.923
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.920
Myo6myosin VI0.895
Atoh7atonal homolog 7 (Drosophila)0.818
Sox2SRY-box containing gene 20.814
Scn5asodium channel, voltage-gated, type V, alpha0.813
Pax6paired box gene 60.778
Trpm1transient receptor potential cation channel, subfamily M, member 10.776
Gucy2eguanylate cyclase 2e0.727
Crxcone-rod homeobox containing gene0.726
Atp6v1aATPase, H+ transporting, lysosomal V1 subunit A0.715
Gja5gap junction protein, alpha 50.704
Raxretina and anterior neural fold homeobox0.684
Pax2paired box gene 20.665
ND6NADH dehydrogenase subunit 60.622
Duox2dual oxidase 20.581
Rbp3retinol binding protein 3, interstitial0.557
Kcnc1potassium voltage gated channel, Shaw-related subfamily, member 10.551
Pcp2Purkinje cell protein 2 (L7)0.537
Lhx3LIM homeobox protein 30.509
Aipl1aryl hydrocarbon receptor-interacting protein-like 10.482
Pex5lperoxisomal biogenesis factor 5-like0.474
Trp53transformation related protein 530.446
Ptenphosphatase and tensin homolog0.426
Otx2orthodenticle homolog 2 (Drosophila)0.406
Tgfb1transforming growth factor, beta 10.401
Thrbthyroid hormone receptor beta0.401
Dlx5distal-less homeobox 50.333
Gnb3guanine nucleotide binding protein (G protein), beta 30.319
LOC100503041PDZ domain-containing protein 7-like0.313
Cacna1fcalcium channel, voltage-dependent, alpha 1F subunit0.306
Pde6gphosphodiesterase 6G, cGMP-specific, rod, gamma0.289
Cav1caveolin 1, caveolae protein0.257
Ptf1apancreas specific transcription factor, 1a0.253
Opn1mwopsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan)0.253
Cplx4complexin 40.244
Guca1aguanylate cyclase activator 1a (retina)0.229
Tshz1teashirt zinc finger family member 10.220
Six6sine oculis-related homeobox 6 homolog (Drosophila)0.215
Cdkn2dcyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)0.200
Guca1bguanylate cyclase activator 1B0.196
RorbRAR-related orphan receptor beta0.181
Pou4f2POU domain, class 4, transcription factor 20.175
Opn1swopsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)0.171
Pcdh15protocadherin 150.170
Cngb3cyclic nucleotide gated channel beta 30.162
Cabp5calcium binding protein 50.159
Cdh23cadherin 23 (otocadherin)0.153
Insm1insulinoma-associated 10.147
Drd4dopamine receptor D40.137
Nrlneural retina leucine zipper gene0.131
Ppardperoxisome proliferator activator receptor delta0.129
Arr3arrestin 3, retinal0.129
BC027072cDNA sequence BC0270720.126
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.125
Gabra2gamma-aminobutyric acid (GABA) A receptor, subunit alpha 20.125
Atp2b2ATPase, Ca++ transporting, plasma membrane 20.120
Runx2runt related transcription factor 20.120
Hcn1hyperpolarization-activated, cyclic nucleotide-gated K+ 10.119
Ppef2protein phosphatase, EF hand calcium-binding domain 20.111
Tbx3T-box 30.107
Myt1myelin transcription factor 10.105
Dlg4discs, large homolog 4 (Drosophila)0.103
Tulp1tubby like protein 10.103
AI118078expressed sequence AI1180780.102
Elavl1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.100
Sult4a1sulfotransferase family 4A, member 10.099
Cacna2d4calcium channel, voltage-dependent, alpha 2/delta subunit 40.096
Drd2dopamine receptor D20.096
Cbln1cerebellin 1 precursor protein0.094
Ush1gUsher syndrome 1G homolog (human)0.094
Gnat2guanine nucleotide binding protein, alpha transducing 20.086
Apcadenomatosis polyposis coli0.080
CblCasitas B-lineage lymphoma0.080
Ncoa1nuclear receptor coactivator 10.078
Grk1G protein-coupled receptor kinase 10.077
Emx1empty spiracles homolog 1 (Drosophila)0.076
Celf4CUGBP, Elav-like family member 40.075
Impg1interphotoreceptor matrix proteoglycan 10.072
Crb1crumbs homolog 1 (Drosophila)0.069
Pax8paired box gene 80.067
Slc12a5solute carrier family 12, member 50.065
Pde6hphosphodiesterase 6H, cGMP-specific, cone, gamma0.065
Ghrgrowth hormone receptor0.065
Dctdopachrome tautomerase0.064
Sagretinal S-antigen0.062
Igf1rinsulin-like growth factor I receptor0.061
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
tbx16T-box gene 160.738
ntlano tail a0.473
bmp4bone morphogenetic protein 40.416
flhfloating head0.393
rxraaretinoid X receptor, alpha a0.362
tbx2aT-box gene 2a0.267
her1hairy-related 10.239
otx2orthodenticle homolog 20.207
tbx2bT-box 2b0.186
ift88intraflagellar transport 88 homolog0.185
otx5orthodenticle homolog 50.172
cdh2cadherin 2, neuronal0.149
rarabretinoic acid receptor, alpha b0.146
dact1dapper homolog 1, antagonist of beta-catenin (xenopus)0.138
crxcone-rod homeobox0.136
has2hyaluronan synthase 20.120
pde6cphosphodiesterase 6C, cGMP-specific, cone, alpha prime0.117
cry3cryptochrome 30.114
wnt11wingless-type MMTV integration site family, member 110.108
tbx1T-box 10.105
tfap2atranscription factor AP-2 alpha0.098
raraaretinoic acid receptor, alpha a0.088
nr2e3nuclear receptor subfamily 2, group E, member 30.086
per3period homolog 3 (Drosophila)0.079
msxcmuscle segment homeobox C0.075
wnt5bwingless-type MMTV integration site family, member 5b0.075
bmp2bbone morphogenetic protein 2b0.070
rxrgaretinoid x receptor, gamma a0.069
six3bsine oculis homeobox homolog 3b0.066
pax2apaired box gene 2a0.060
kif17kinesin family member 170.060
arr3aarrestin 3a, retinal (X-arrestin)0.060
pcdh8protocadherin 80.056
rxrbaretinoid x receptor, beta a0.054
tbx5aT-box 5a0.054
pkd2polycystic kidney disease 20.050
vcanbversican b0.049
loxl3blysyl oxidase-like 3b0.045
fgf10afibroblast growth factor 10a0.044
rx3retinal homeobox gene 30.044
hapln1ahyaluronan and proteoglycan link protein 1a0.044
rargbretinoic acid receptor, gamma b0.042
gngt2aguanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2a0.040
cyp26a1cytochrome P450, subfamily XXVIA, polypeptide 10.040
shhasonic hedgehog a0.039
dlg1discs, large (Drosophila) homolog 10.037
aanat2arylalkylamine N-acetyltransferase0.036
fgf8afibroblast growth factor 8 a0.033
atoh7atonal homolog 70.033
mibmind bomb0.033
crb2acrumbs homolog 2a0.032
brd2bbromodomain containing 2b0.031
vcanaversican a0.030
eomesaeomesodermin homolog a0.030
nkx2.5NK2 transcription factor related 50.029
dlx6adistal-less homeobox gene 6a0.029
myod1myogenic differentiation 10.026
rorcbRAR-related orphan receptor C b0.026
mib2mind bomb 20.026
prrx1bpaired related homeobox 1b0.026
smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.025
fezf2FEZ family zinc finger 20.024
slc25a37solute carrier family 25, member 370.024
hoxd11ahomeo box D11a0.024
cacnb2bcalcium channel, voltage-dependent, beta 2b0.024
pvrl1apoliovirus receptor-related 1a0.023
her7hairy and enhancer of split related-70.023
slc12a2solute carrier family 12 (potassium/chloride transporters), member 20.022
nr1d2anuclear receptor subfamily 1, group D, member 2a0.022
lratblecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b)0.022
eya1eyes absent homolog 10.021
tcf7transcription factor 7 (T-cell specific, HMG-box)0.021
cdx4caudal type homeo box transcription factor 40.021
clrn1clarin 10.020
guk1guanylate kinase 10.020
hoxa13ahomeo box A13a0.020
tbx24T-box 240.019
tgfbitransforming growth factor, beta-induced0.019
aldh1a2aldehyde dehydrogenase 1 family, member A20.019
fgf3fibroblast growth factor 30.018
tcf21transcription factor 210.018
cart1cartilage paired-class homeoprotein 10.018
jhdm1dajumonji C domain containing histone demethylase 1 homolog Da (S. cerevisiae)0.017
scn12absodium channel, voltage gated, type XII, alpha b0.017
foxg1aforkhead box G1a0.017
gngt1guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 10.017
irx7iroquois homeobox protein 70.016
six3asine oculis homeobox homolog 3a0.016
crabp2acellular retinoic acid binding protein 2, a0.016
vsx1visual system homeobox 1 homolog, chx10-like0.016
sema3hsemaphorin 3h0.016
myf5myogenic factor 50.015
hoxc8ahomeo box C8a0.015
dlx2adistal-less homeobox gene 2a0.015
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism