The network for 'negative regulation of intracellular signal transduction' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of intracellular signal transduction

Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction.

NameDescriptionProbabilityFunc Analog Organism
Apcadenomatosis polyposis coli0.994
Cd44CD44 antigen0.993
Lyz2lysozyme 20.991
Nr3c1nuclear receptor subfamily 3, group C, member 10.959
Leprleptin receptor0.958
Stat3signal transducer and activator of transcription 30.936
Mdm2transformed mouse 3T3 cell double minute 20.912
Ptprcprotein tyrosine phosphatase, receptor type, C0.905
Map3k7mitogen-activated protein kinase kinase kinase 70.897
Mapk1mitogen-activated protein kinase 10.892
Ptgs2prostaglandin-endoperoxide synthase 20.890
Tnfaip3tumor necrosis factor, alpha-induced protein 30.876
Traf6TNF receptor-associated factor 60.875
Cav1caveolin 1, caveolae protein0.871
Ctnnb1catenin (cadherin associated protein), beta 10.870
Atf2activating transcription factor 20.831
Rb1retinoblastoma 10.810
SkilSKI-like0.735
Sqstm1sequestosome 10.732
Prkccprotein kinase C, gamma0.725
Myd88myeloid differentiation primary response gene 880.719
Ikbkbinhibitor of kappaB kinase beta0.703
Yap1yes-associated protein 10.697
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.697
Ghrgrowth hormone receptor0.694
Mapk14mitogen-activated protein kinase 140.673
Nf2neurofibromatosis 20.664
Prkceprotein kinase C, epsilon0.653
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.649
Bmp4bone morphogenetic protein 40.637
Ptenphosphatase and tensin homolog0.636
Ubcubiquitin C0.605
Smad1MAD homolog 1 (Drosophila)0.601
Ccnd1cyclin D10.599
Trp53transformation related protein 530.594
CblCasitas B-lineage lymphoma0.593
Smad4MAD homolog 4 (Drosophila)0.576
Cyldcylindromatosis (turban tumor syndrome)0.570
Tnftumor necrosis factor0.561
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.546
Spry4sprouty homolog 4 (Drosophila)0.541
Clockcircadian locomotor output cycles kaput0.536
Ighimmunoglobulin heavy chain complex0.534
Grb10growth factor receptor bound protein 100.529
Selpselectin, platelet0.523
Insrinsulin receptor0.522
Mdm4transformed mouse 3T3 cell double minute 40.516
C1qccomplement component 1, q subcomponent, C chain0.515
Nos1nitric oxide synthase 1, neuronal0.512
Ptpn11protein tyrosine phosphatase, non-receptor type 110.510
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.505
Il1r1interleukin 1 receptor, type I0.497
Itga3integrin alpha 30.495
Cd40CD40 antigen0.495
WasWiskott-Aldrich syndrome homolog (human)0.491
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.483
Thbs1thrombospondin 10.480
AxlAXL receptor tyrosine kinase0.471
Sfrp2secreted frizzled-related protein 20.468
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.466
Plcg1phospholipase C, gamma 10.466
Itsn1intersectin 1 (SH3 domain protein 1A)0.465
Adam17a disintegrin and metallopeptidase domain 170.451
Abl1c-abl oncogene 1, non-receptor tyrosine kinase0.446
Ldb3LIM domain binding 30.445
Socs1suppressor of cytokine signaling 10.442
Wt1Wilms tumor 1 homolog0.425
S1pr2sphingosine-1-phosphate receptor 20.418
Vaspvasodilator-stimulated phosphoprotein0.407
Socs3suppressor of cytokine signaling 30.406
Grb2growth factor receptor bound protein 20.399
CrebbpCREB binding protein0.394
Nos3nitric oxide synthase 3, endothelial cell0.390
Ncoa3nuclear receptor coactivator 30.388
Ahraryl-hydrocarbon receptor0.388
BtkBruton agammaglobulinemia tyrosine kinase0.387
Bdkrb2bradykinin receptor, beta 20.385
Prkcbprotein kinase C, beta0.383
Hoxd13homeobox D130.369
Pthlhparathyroid hormone-like peptide0.368
Hic1hypermethylated in cancer 10.365
Hif1ahypoxia inducible factor 1, alpha subunit0.365
Tead3TEA domain family member 30.361
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.360
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.355
Snai1snail homolog 1 (Drosophila)0.355
Foxf1aforkhead box F1a0.353
Il1binterleukin 1 beta0.352
Slc34a1solute carrier family 34 (sodium phosphate), member 10.346
Cd86CD86 antigen0.343
Mapk11mitogen-activated protein kinase 110.341
Cry2cryptochrome 2 (photolyase-like)0.339
Gsk3bglycogen synthase kinase 3 beta0.337
Arrb2arrestin, beta 20.337
Cacng2calcium channel, voltage-dependent, gamma subunit 20.336
Gnaqguanine nucleotide binding protein, alpha q polypeptide0.336
Hbegfheparin-binding EGF-like growth factor0.336
S1pr3sphingosine-1-phosphate receptor 30.334
Egfrepidermal growth factor receptor0.333
Smad3MAD homolog 3 (Drosophila)0.329
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
goa-1Protein GOA-10.021
pkg-1Protein PKG-10.019
egl-18Protein EGL-180.017
vab-3Protein VAB-30.015
F36D4.5Protein F36D4.50.014
mec-2Protein MEC-20.014
plc-1Protein PLC-10.013
inx-12Protein INX-120.013
ida-1Protein IDA-10.013
inx-13Protein INX-130.012
pdfr-1Protein PDFR-10.012
eps-8Protein EPS-80.012
unc-7Protein UNC-70.011
rhi-1Protein RHI-10.011
puf-5Protein PUF-50.011
exc-5Protein EXC-50.011
unc-43Protein UNC-430.010
nhr-6Protein NHR-60.010
hgrs-1Protein HGRS-10.010
lin-66Protein LIN-660.010
pry-1Protein PRY-10.010
plc-3Protein PLC-30.010
kgb-1Protein KGB-10.010
unc-104Protein UNC-1040.010
gpb-1Protein GPB-10.010
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
fgf3fibroblast growth factor 30.238
nf1aneurofibromin 1a0.185
chdchordin0.156
odc1ornithine decarboxylase 10.151
spry4sprouty (Drosophila) homolog 40.137
nr3c1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.137
per3period homolog 3 (Drosophila)0.110
sox9bSRY-box containing gene 9b0.106
mmp9matrix metalloproteinase 90.088
myod1myogenic differentiation 10.080
efnb2aephrin B2a0.078
acvr1bactivin A receptor, type IB0.076
rarabretinoic acid receptor, alpha b0.072
tbx20T-box 200.068
bcl2l1bcl2-like 10.067
etv5aets variant 5a0.064
ptgs2aprostaglandin-endoperoxide synthase 2a0.063
cdkn1ccyclin-dependent kinase inhibitor 1C (p57, Kip2)0.058
fgfr1afibroblast growth factor receptor 1a0.056
apoebapolipoprotein Eb0.056
mcl1bmyeloid cell leukemia sequence 1b0.055
epha4aeph receptor A4a0.049
egr1early growth response 10.049
fynaFYN oncogene related to SRC, FGR, YES a0.049
mcl1amyeloid cell leukemia sequence 1a0.048
zgc:113159zgc:1131590.046
wnt11rwingless-type MMTV integration site family, member 11, related0.046
itgb1aintegrin, beta 1a0.044
gadd45aagrowth arrest and DNA-damage-inducible, alpha, a0.044
mapk3mitogen-activated protein kinase 30.044
crabp2bcellular retinoic acid binding protein 2, b0.042
tob1atransducer of ERBB2, 1a0.042
znf703zinc finger protein 7030.042
tlr3toll-like receptor 30.041
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.040
adipor2adiponectin receptor 20.039
inspreproinsulin0.039
whsc1Wolf-Hirschhorn syndrome candidate 10.039
itgb1b.2integrin, beta 1b.20.039
gnb1aguanine nucleotide binding protein (G protein), beta polypeptide 1a0.039
trpm7transient receptor potential cation channel, subfamily M, member 70.039
stat1asignal transduction and activation of transcription 1a0.038
dlatdihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)0.037
zgc:55813zgc:558130.036
tnfrsfatumor necrosis factor receptor superfamily, member a0.036
hcrthypocretin (orexin) neuropeptide precursor0.036
zgc:91870zgc:918700.035
ocrloculocerebrorenal syndrome of Lowe0.035
ptprkprotein tyrosine phosphatase, receptor type, K0.035
spry2sprouty homolog 20.035
cx43connexin 430.033
lef1lymphocyte enhancer binding factor 10.032
matn4matrilin 40.031
socs3asuppressor of cytokine signaling 3a0.031
id2ainhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a0.031
cdiptCDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)0.030
foxi3bforkhead box I3b0.030
ntn2netrin 20.030
cdh17cadherin 17, LI cadherin (liver-intestine)0.029
prkaa1protein kinase, AMP-activated, alpha 1 catalytic subunit0.029
zbtb4zinc finger and BTB domain containing 40.029
tbx2bT-box 2b0.029
fzd8afrizzled homolog 8a0.029
sema3aasemaphorin 3aa0.028
bmp2bbone morphogenetic protein 2b0.028
furinafurin (paired basic amino acid cleaving enzyme) a0.028
igf2ainsulin-like growth factor 2a0.027
atrxalpha thalassemia/mental retardation syndrome X-linked homolog (human)0.027
msi1musashi homolog 1 (Drosophila)0.027
sec24cSEC24 family, member C (S. cerevisiae)0.027
esco2establishment of cohesion 1 homolog 20.027
ip6k2inositol hexaphosphate kinase 20.027
nfkbiabnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b0.027
LOC567131calcitonin gene-related peptide type 1 receptor-like0.026
metrnlmeteorin, glial cell differentiation regulator-like0.026
gclcglutamate-cysteine ligase, catalytic subunit0.026
tp53bp2tumor protein p53 binding protein, 20.025
eno2enolase 20.025
eya2eyes absent homolog 2 (Drosophila)0.025
sox10SRY-box containing gene 100.025
LOC100537975thyroid receptor-interacting protein 11-like0.024
sid4secreted immunoglobulin domain 40.024
ahi1Abelson helper integration site 10.024
smad7MAD, mothers against decapentaplegic homolog 7 (Drosophila)0.024
slit3slit (Drosophila) homolog 30.024
im:7164961im:71649610.023
mycbp2MYC binding protein 20.023
itgb1bintegrin, beta 1b0.023
gpr126G protein-coupled receptor 1260.023
stk11serine/threonine kinase 110.023
LOC100000332e3 ubiquitin-protein ligase RNF182-like0.023
zc3h13zinc finger CCCH-type containing 130.023
trpv4transient receptor potential cation channel, subfamily V, member 40.023
pcnaproliferating cell nuclear antigen0.023
sassarcoma amplified sequence0.022
phc2polyhomeotic-like 2 (Drosophila)0.022
zgc:172136zgc:1721360.022
sod1superoxide dismutase 1, soluble0.022
zgc:64114zgc:641140.022
tpm3tropomyosin 30.021
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
rlrolled0.861
Pi3K92ECG4141 gene product from transcript CG4141-RB0.861
kaykayak0.760
Akt1CG4006 gene product from transcript CG4006-RA0.731
krzkurtz0.696
Atg1Autophagy-specific gene 10.633
hpohippo0.611
keykenny0.553
Pka-C1cAMP-dependent protein kinase 10.513
putpunt0.507
InRInsulin-like receptor0.470
hephemipterous0.450
dcodiscs overgrown0.447
p53CG33336 gene product from transcript CG33336-RB0.372
NFATNFAT homolog0.369
shnschnurri0.321
par-1CG8201 gene product from transcript CG8201-RA0.317
dmdiminutive0.312
pucpuckered0.304
S6kRPS6-p70-protein kinase0.265
Tsc1CG6147 gene product from transcript CG6147-RA0.254
Ras64BRas oncogene at 64B0.251
hipkhomeodomain interacting protein kinase0.247
LnkCG17367 gene product from transcript CG17367-RC0.237
alphalphabet0.233
AGO2Argonaute 20.232
chicoCG5686 gene product from transcript CG5686-RB0.231
chercheerio0.228
p38bCG7393 gene product from transcript CG7393-RA0.226
wtswarts0.216
Atg13Autophagy-specific gene 130.203
ttktramtrack0.175
cindrCIN85 and CD2AP orthologue0.171
edechinoid0.169
MerMerlin0.167
CG8155CG8155 gene product from transcript CG8155-RA0.162
mysmyospheroid0.157
Rab7Rab-protein 70.151
captcapulet0.149
dxdeltex0.145
Hsc70-4Heat shock protein cognate 40.144
brkbrinker0.140
PGRP-LCPeptidoglycan recognition protein LC0.136
Myo31DFMyosin 31DF0.134
Caf1Chromatin assembly factor 1 subunit0.130
CycDCyclin D0.128
nctnicastrin0.126
fs(1)hfemale sterile (1) homeotic0.123
sxcsuper sex combs0.121
mnbminibrain0.120
AttAAttacin-A0.116
nmonemo0.114
CycGCyclin G0.114
apapterous0.113
panpangolin0.110
agoarchipelago0.110
fz2frizzled 20.107
Pk61CProtein kinase 61C0.106
DptBDiptericin B0.099
roboroundabout0.097
Mkp3Mitogen-activated protein kinase phosphatase 30.096
drkdownstream of receptor kinase0.092
ash2absent, small, or homeotic discs 20.091
rawCG12437 gene product from transcript CG12437-RB0.091
saxsaxophone0.091
Atg18Autophagy-specific gene 180.089
CkaConnector of kinase to AP-10.089
linlines0.088
RhebCG1081 gene product from transcript CG1081-RA0.085
POSHPlenty of SH3s0.085
eIF-4aEukaryotic initiation factor 4a0.084
Tab2TAK1-associated binding protein 20.082
Sin3ACG8815 gene product from transcript CG8815-RC0.081
shishibire0.081
Mpk2CG5475 gene product from transcript CG5475-RB0.080
AckCG14992 gene product from transcript CG14992-RA0.079
kiskismet0.079
MoeMoesin0.079
RelRelish0.075
Ten-mTenascin major0.075
CG8090CG8090 gene product from transcript CG8090-RB0.075
PGRP-SDCG7496 gene product from transcript CG7496-RA0.075
Arr2Arrestin 20.074
ApcAPC-like0.073
cnkconnector enhancer of ksr0.072
Spn27ASerpin 27A0.072
scbscab0.071
phlpole hole0.071
aopanterior open0.071
smosmoothened0.070
cazcabeza0.070
CG5794CG5794 gene product from transcript CG5794-RB0.070
EgfrEpidermal growth factor receptor0.070
SmrSmrter0.070
ThorCG8846 gene product from transcript CG8846-RA0.069
trptransient receptor potential0.069
Mekk1CG7717 gene product from transcript CG7717-RB0.069
sogshort gastrulation0.069
MtkMetchnikowin0.069
chbchromosome bows0.069
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PTPN1protein tyrosine phosphatase, non-receptor type 10.998
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.995
UBCubiquitin C0.992
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.991
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.989
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.973
MAP3K7mitogen-activated protein kinase kinase kinase 70.970
FYNFYN oncogene related to SRC, FGR, YES0.966
MAPK14mitogen-activated protein kinase 140.952
ESR1estrogen receptor 10.943
MAPK1mitogen-activated protein kinase 10.938
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.907
GRB2growth factor receptor-bound protein 20.895
CASP8caspase 8, apoptosis-related cysteine peptidase0.891
TP53tumor protein p530.876
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.875
PDCD6IPprogrammed cell death 6 interacting protein0.873
EGFRepidermal growth factor receptor0.857
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.854
HDAC1histone deacetylase 10.846
BCL2B-cell CLL/lymphoma 20.824
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.806
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.771
GHRgrowth hormone receptor0.761
NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.755
YAP1Yes-associated protein 10.737
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.735
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.718
MAPK8mitogen-activated protein kinase 80.707
SH3KBP1SH3-domain kinase binding protein 10.694
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.693
METmet proto-oncogene (hepatocyte growth factor receptor)0.683
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.649
ZNF43zinc finger protein 430.618
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.607
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.599
BTRCbeta-transducin repeat containing0.583
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.557
PRKCZprotein kinase C, zeta0.552
LCP2lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)0.542
GSK3Bglycogen synthase kinase 3 beta0.506
FBXW11F-box and WD repeat domain containing 110.502
BMI1BMI1 polycomb ring finger oncogene0.498
SHC1SHC (Src homology 2 domain containing) transforming protein 10.498
CFLARCASP8 and FADD-like apoptosis regulator0.494
CASP3caspase 3, apoptosis-related cysteine peptidase0.479
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.465
SQSTM1sequestosome 10.463
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.461
MPDZmultiple PDZ domain protein0.442
JUNjun proto-oncogene0.433
PMLpromyelocytic leukemia0.422
FASFas (TNF receptor superfamily, member 6)0.420
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.412
CREBBPCREB binding protein0.412
DUSP1dual specificity phosphatase 10.402
FHL2four and a half LIM domains 20.400
TRAF6TNF receptor-associated factor 60.387
TSC2tuberous sclerosis 20.384
KEAP1kelch-like ECH-associated protein 10.383
BIRC2baculoviral IAP repeat containing 20.380
CHUKconserved helix-loop-helix ubiquitous kinase0.371
PTK2BPTK2B protein tyrosine kinase 2 beta0.364
RNF11ring finger protein 110.352
CASP10caspase 10, apoptosis-related cysteine peptidase0.349
MAFAv-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)0.344
PTK2PTK2 protein tyrosine kinase 20.332
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein0.329
PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha0.329
BCAR1breast cancer anti-estrogen resistance 10.325
RICTORRPTOR independent companion of MTOR, complex 20.322
TNFRSF10Btumor necrosis factor receptor superfamily, member 10b0.318
INSRinsulin receptor0.314
MYD88myeloid differentiation primary response gene (88)0.304
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.302
CDC25Acell division cycle 25 homolog A (S. pombe)0.300
ZNF746zinc finger protein 7460.297
PTENphosphatase and tensin homolog0.294
TNFRSF10Atumor necrosis factor receptor superfamily, member 10a0.290
GUCY2Cguanylate cyclase 2C (heat stable enterotoxin receptor)0.288
SMAD3SMAD family member 30.281
ZNF253zinc finger protein 2530.279
SYKspleen tyrosine kinase0.278
BMPR1Abone morphogenetic protein receptor, type IA0.277
CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)0.277
ZNF273zinc finger protein 2730.271
OPTNoptineurin0.264
LCKlymphocyte-specific protein tyrosine kinase0.263
MAP2K4mitogen-activated protein kinase kinase 40.262
VCPvalosin containing protein0.262
MAPKAPK2mitogen-activated protein kinase-activated protein kinase 20.259
BCL2L1BCL2-like 10.259
NCOR2nuclear receptor corepressor 20.258
CBX5chromobox homolog 50.255
MED28mediator complex subunit 280.254
RELBv-rel reticuloendotheliosis viral oncogene homolog B0.253
MAP2K3mitogen-activated protein kinase kinase 30.253
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.253
UBE2Bubiquitin-conjugating enzyme E2B (RAD6 homolog)0.251
TNFRSF6Btumor necrosis factor receptor superfamily, member 6b, decoy0.250
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Vdac1voltage-dependent anion channel 10.115
Klf2Kruppel-like factor 2 (lung)0.102
Errfi1ERBB receptor feedback inhibitor 10.088
Klf6Kruppel-like factor 60.083
Rab1bRAB1B, member RAS oncogene family0.071
Anxa1annexin A10.059
Dlg3discs, large homolog 3 (Drosophila)0.057
Capgcapping protein (actin filament), gelsolin-like0.051
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.048
Mpp2membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)0.048
LOC100362824caveolin 2-like0.046
Pdk2pyruvate dehydrogenase kinase, isozyme 20.046
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.045
Klf4Kruppel-like factor 4 (gut)0.045
Tsc22d3TSC22 domain family, member 30.044
Jdp2Jun dimerization protein 20.043
Prkcdprotein kinase C, delta0.042
Sirpasignal-regulatory protein alpha0.041
Jak1Janus kinase 10.040
Jak2Janus kinase 20.040
SnrkSNF related kinase0.039
Usf2upstream transcription factor 2, c-fos interacting0.038
Caskcalcium/calmodulin-dependent serine protein kinase (MAGUK family)0.036
Junbjun B proto-oncogene0.035
Nos3nitric oxide synthase 3, endothelial cell0.035
CnbpCCHC-type zinc finger, nucleic acid binding protein0.035
Vegfavascular endothelial growth factor A0.035
Efnb1ephrin B10.035
Cct4chaperonin containing Tcp1, subunit 4 (delta)0.034
Crip2cysteine-rich protein 20.034
Cdc37cell division cycle 37 homolog (S. cerevisiae)0.033
Matkmegakaryocyte-associated tyrosine kinase0.033
Hoxa1homeo box A10.032
Pacs1phosphofurin acidic cluster sorting protein 10.032
Ddndendrin0.032
Fmnl1formin-like 10.032
Pdp1pyruvate dehyrogenase phosphatase catalytic subunit 10.032
TufmTu translation elongation factor, mitochondrial0.032
Mgat3mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase0.032
Adam10ADAM metallopeptidase domain 100.031
Sh2b3SH2B adaptor protein 30.031
Foxe3forkhead box E30.031
Grin2aglutamate receptor, ionotropic, N-methyl D-aspartate 2A0.030
Zfp36zinc finger protein 360.029
Rararetinoic acid receptor, alpha0.029
Cand1cullin-associated and neddylation-dissociated 10.028
Gja1gap junction protein, alpha 10.028
RT1-DMaRT1 class II, locus DMa0.028
RT1-Db1RT1 class II, locus Db10.027
Utrnutrophin0.027
Myd88myeloid differentiation primary response gene 880.027
Grin1glutamate receptor, ionotropic, N-methyl D-aspartate 10.027
Apba3amyloid beta (A4) precursor protein-binding, family A, member 30.027
Ppm1bprotein phosphatase 1B, magnesium dependent, beta isoform0.027
Tgfb1transforming growth factor, beta 10.026
JunJun oncogene0.026
Tgfbr3transforming growth factor, beta receptor III0.026
Actr2ARP2 actin-related protein 2 homolog (yeast)0.025
Map3k3mitogen activated protein kinase kinase kinase 30.025
Map2microtubule-associated protein 20.025
Ralgdsral guanine nucleotide dissociation stimulator0.025
Tcfe2atranscription factor E2a0.025
Cmtm6CKLF-like MARVEL transmembrane domain containing 60.025
Rcsd1RCSD domain containing 10.025
Stat6signal transducer and activator of transcription 60.025
Xpo1exportin 1, CRM1 homolog (yeast)0.024
Tle4transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)0.024
Atp1a1ATPase, Na+/K+ transporting, alpha 1 polypeptide0.024
Smad4SMAD family member 40.024
Creb1cAMP responsive element binding protein 10.024
Rasgrp1RAS guanyl releasing protein 1 (calcium and DAG-regulated)0.024
Mapk3mitogen activated protein kinase 30.024
Smad7SMAD family member 70.024
Epn2epsin 20.024
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.024
Slc14a2solute carrier family 14 (urea transporter), member 20.024
Baiap2BAI1-associated protein 20.024
Scarb1scavenger receptor class B, member 10.024
Homer1homer homolog 1 (Drosophila)0.023
Anxa5annexin A50.023
Tcf12transcription factor 120.023
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.023
Ifitm3interferon induced transmembrane protein 30.023
Myo1bmyosin Ib0.023
Ctnnd2catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)0.023
Syt3synaptotagmin III0.022
Btg2BTG family, member 20.022
Gna12guanine nucleotide binding protein (G protein) alpha 120.022
Cacna1ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.022
Anxa2annexin A20.022
RT1-DMbRT1 class II, locus DMb0.021
Exoc5exocyst complex component 50.021
Rassf5Ras association (RalGDS/AF-6) domain family member 50.021
Qarsglutaminyl-tRNA synthetase0.021
Slfn2schlafen 20.021
Gprc5aG protein-coupled receptor, family C, group 5, member A0.021
Cdc42bpbCDC42 binding protein kinase beta (DMPK-like)0.021
Cishcytokine inducible SH2-containing protein0.020
Cldn2claudin 20.020
Tspotranslocator protein0.020
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
BCK1Bck1p0.926
CDC24Cdc24p0.599
KSS1Kss1p0.572
CLA4Cla4p0.564
GPB2Gpb2p0.532
BOI1Boi1p0.518
CAK1Cak1p0.423
FUS3Fus3p0.418
MSG5Msg5p0.370
IRA1Ira1p0.368
SLT2Slt2p0.345
RHO1Rho1p0.305
FAR1Far1p0.302
CDC25Cdc25p0.280
PBS2Pbs2p0.277
ROM2Rom2p0.270
DED1Ded1p0.258
MDS3Mds3p0.220
MKK1Mkk1p0.215
CDC55Cdc55p0.209
PPH21Pph21p0.174
STE7Ste7p0.171
PSP2Psp2p0.160
PHO85Pho85p0.147
PRR1Prr1p0.142
YDL233Whypothetical protein0.140
RLM1Rlm1p0.140
FAB1Fab1p0.139
VPS5Vps5p0.137
STE20Ste20p0.136
GSC2Gsc2p0.136
STE12Ste12p0.134
KEM1Kem1p0.133
SAP190Sap190p0.120
ACK1Ack1p0.119
KDX1Kdx1p0.105
PIL1Pil1p0.103
CHS1Chs1p0.102
LHS1Lhs1p0.098
ENT1Ent1p0.097
URN1Urn1p0.096
MKK2Mkk2p0.096
MYO5Myo5p0.096
RAS2Ras2p0.094
DIG1Dig1p0.094
GPR1Gpr1p0.079
LSB1Lsb1p0.079
IWR1Iwr1p0.077
TPK2Tpk2p0.076
CYR1Cyr1p0.075
SAC7Sac7p0.073
BEM1Bem1p0.073
HKR1Hkr1p0.072
IRA2Ira2p0.071
YSC84Ysc84p0.071
NAT1Nat1p0.071
LEA1Lea1p0.070
HSM3Hsm3p0.068
PTC2Ptc2p0.065
CDC4Cdc4p0.063
STE11Ste11p0.063
BST1Bst1p0.062
SKT5Skt5p0.061
WWM1Wwm1p0.059
BOI2Boi2p0.057
BEM3Bem3p0.057
MRL1Mrl1p0.056
RTS1Rts1p0.054
CYK3Cyk3p0.053
DST1Dst1p0.052
INP53Inp53p0.051
YME1Yme1p0.051
SWE1Swe1p0.051
BEM2Bem2p0.051
SBE2Sbe2p0.050
PKH2Pkh2p0.048
YHB1Yhb1p0.048
SSN8Ssn8p0.048
MKT1Mkt1p0.048
HSL7Hsl7p0.047
UBP5Ubp5p0.046
FYV8Fyv8p0.046
SAK1Sak1p0.045
OSH3Osh3p0.045
PTP2Ptp2p0.045
CYC8Cyc8p0.044
TIP41Tip41p0.044
TPS1Tps1p0.044
ZRG8Zrg8p0.043
RRD1Rrd1p0.042
YJU2Yju2p0.042
SUR1Sur1p0.042
SLA2Sla2p0.042
ROM1Rom1p0.042
VAC7Vac7p0.041
MSS11Mss11p0.041
SCH9Sch9p0.040
RIM15Rim15p0.040
MUB1Mub1p0.040
BCK2Bck2p0.038