The network for 'melanosome organization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

melanosome organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.

NameDescriptionProbabilityFunc Analog Organism
Tyrp1tyrosinase-related protein 10.994
Hps1Hermansky-Pudlak syndrome 1 homolog (human)0.994
Mitfmicrophthalmia-associated transcription factor0.979
Lystlysosomal trafficking regulator0.951
Oca2oculocutaneous albinism II0.949
Rab27aRAB27A, member RAS oncogene family0.928
Hps5Hermansky-Pudlak syndrome 5 homolog (human)0.853
Hps6Hermansky-Pudlak syndrome 60.845
Pmelpremelanosome protein0.683
Kitkit oncogene0.641
Atp6v0bATPase, H+ transporting, lysosomal V0 subunit B0.512
Ap3d1adaptor-related protein complex 3, delta 1 subunit0.326
Hps4Hermansky-Pudlak syndrome 4 homolog (human)0.272
Rab38RAB38, member of RAS oncogene family0.246
Ap3b1adaptor-related protein complex 3, beta 1 subunit0.213
Slc24a5solute carrier family 24, member 50.113
Slc45a2solute carrier family 45, member 20.097
Myo5amyosin VA0.094
Hps3Hermansky-Pudlak syndrome 3 homolog (human)0.056
Dtnbp1dystrobrevin binding protein 10.055
Mc1rmelanocortin 1 receptor0.052
Atp6v0cATPase, H+ transporting, lysosomal V0 subunit C0.037
Kitlkit ligand0.035
Ednrbendothelin receptor type B0.028
2810422J05RikRIKEN cDNA 2810422J05 gene0.028
Ap1g1adaptor protein complex AP-1, gamma 1 subunit0.024
Rp1retinitis pigmentosa 1 (human)0.023
Slc26a4solute carrier family 26, member 40.022
Foxc1forkhead box C10.021
Vps4avacuolar protein sorting 4a (yeast)0.021
Pax3paired box gene 30.017
Trpm1transient receptor potential cation channel, subfamily M, member 10.015
Myo6myosin VI0.014
Ap2m1adaptor protein complex AP-2, mu10.012
Ctbp1C-terminal binding protein 10.011
Prrx1paired related homeobox 10.011
Snx3sorting nexin 30.010
Ap2s1adaptor-related protein complex 2, sigma 1 subunit0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
atp6ap1ATPase, H+ transporting, lysosomal accessory protein 10.882
dctdopachrome tautomerase0.756
mitfamicrophthalmia-associated transcription factor a0.733
pmelapremelanosome protein a0.620
atp6v1hATPase, H+ transporting, lysosomal, V1 subunit H0.617
tyrp1btyrosinase-related protein 1b0.528
atp6v0caATPase, H+ transporting, lysosomal, V0 subunit c, a0.398
atp6v0d1ATPase, H+ transporting, V0 subunit D isoform 10.290
slc24a5solute carrier family 24, member 50.136
slc45a2solute carrier family 45, member 20.101
atp6ap2ATPase, H+ transporting, lysosomal accessory protein 20.093
grem2gremlin 2, cysteine knot superfamily0.069
atp6v1e1bATPase, H+ transporting, lysosomal, V1 subunit E isoform 1b0.063
ltkleukocyte tyrosine kinase0.045
sox10SRY-box containing gene 100.044
vps39vacuolar protein sorting 39 homolog (S. cerevisiae)0.038
hoxb3ahomeo box B3a0.038
csf1racolony stimulating factor 1 receptor, a0.032
tfectranscription factor EC0.030
cox4nbcox4 neighbor0.030
gch2GTP cyclohydrolase 20.030
pnp4apurine nucleoside phosphorylase 4a0.027
tyrp1tyrosinase-related protein 10.026
stxbp2syntaxin binding protein 20.020
sdf4stromal cell derived factor 40.017
zmiz1zinc finger, MIZ-type containing 10.016
creb3l3lcAMP responsive element binding protein 3-like 3 like0.016
dtnbp1adystrobrevin binding protein 1a0.014
flncbfilamin C, gamma b (actin binding protein 280)0.013
aox3aldehyde oxidase 30.013
fabp11bfatty acid binding protein 11b0.013
kitakit receptor a0.012
ctsdcathepsin D0.012
atp1a1a.2ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide0.011
kcnj13potassium inwardly-rectifying channel, subfamily J, member 130.011
gmppbGDP-mannose pyrophosphorylase B0.011
ctsccathepsin C0.011
foxn4forkhead box N40.010
dpysl3dihydropyrimidinase-like 30.010
hmx4H6 family homeobox 40.010
atp6v1fATPase, H+ transporting, V1 subunit F0.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ATP6V0CATPase, H+ transporting, lysosomal 16kDa, V0 subunit c0.207
CLASP1cytoplasmic linker associated protein 10.125
AP2B1adaptor-related protein complex 2, beta 1 subunit0.115
NEU1sialidase 1 (lysosomal sialidase)0.030
EPS15L1epidermal growth factor receptor pathway substrate 15-like 10.021
ATP6V0BATPase, H+ transporting, lysosomal 21kDa, V0 subunit b0.014
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism