The network for 'cell migration involved in gastrulation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cell migration involved in gastrulation

The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression).

NameDescriptionProbabilityFunc Analog Organism
Ctnnb1catenin (cadherin associated protein), beta 11.000
Pitx2paired-like homeodomain transcription factor 21.000
Fgfr2fibroblast growth factor receptor 20.999
Shhsonic hedgehog0.999
Gli3GLI-Kruppel family member GLI30.997
Foxc1forkhead box C10.995
Bmp4bone morphogenetic protein 40.983
Tbx3T-box 30.977
Fgf8fibroblast growth factor 80.973
Pax3paired box gene 30.965
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.956
Foxh1forkhead box H10.951
Vangl2vang-like 2 (van gogh, Drosophila)0.937
Meox2mesenchyme homeobox 20.933
Jag1jagged 10.930
Prrx1paired related homeobox 10.926
Sox2SRY-box containing gene 20.924
Efnb2ephrin B20.916
Otx2orthodenticle homolog 2 (Drosophila)0.909
Bmpr1abone morphogenetic protein receptor, type 1A0.896
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.889
Bmp7bone morphogenetic protein 70.864
Hand1heart and neural crest derivatives expressed transcript 10.830
Fgfr1fibroblast growth factor receptor 10.829
Gata4GATA binding protein 40.822
Zic3zinc finger protein of the cerebellum 30.821
Tgfb2transforming growth factor, beta 20.809
Pcsk5proprotein convertase subtilisin/kexin type 50.805
Egfrepidermal growth factor receptor0.755
Pax2paired box gene 20.736
Fgfr3fibroblast growth factor receptor 30.732
Ror2receptor tyrosine kinase-like orphan receptor 20.722
Robo1roundabout homolog 1 (Drosophila)0.709
Sox11SRY-box containing gene 110.697
Foxc2forkhead box C20.692
Nos3nitric oxide synthase 3, endothelial cell0.690
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.682
Fgf10fibroblast growth factor 100.680
Wnt5awingless-related MMTV integration site 5A0.673
Rargretinoic acid receptor, gamma0.673
Tbx1T-box 10.645
Bdnfbrain derived neurotrophic factor0.636
Cfc1cripto, FRL-1, cryptic family 10.630
Smad4MAD homolog 4 (Drosophila)0.625
Isl1ISL1 transcription factor, LIM/homeodomain0.618
Pitx1paired-like homeodomain transcription factor 10.613
Ptpn11protein tyrosine phosphatase, non-receptor type 110.606
Lrp6low density lipoprotein receptor-related protein 60.582
Hes1hairy and enhancer of split 1 (Drosophila)0.577
Apcadenomatosis polyposis coli0.564
Tcfap2atranscription factor AP-2, alpha0.545
Hoxa13homeobox A130.524
Lrp2low density lipoprotein receptor-related protein 20.517
Zeb1zinc finger E-box binding homeobox 10.511
Msx2homeobox, msh-like 20.506
Ntf3neurotrophin 30.503
Slit3slit homolog 3 (Drosophila)0.495
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.481
Gli2GLI-Kruppel family member GLI20.474
Smad6MAD homolog 6 (Drosophila)0.450
Hand2heart and neural crest derivatives expressed transcript 20.445
Sox7SRY-box containing gene 70.440
Hoxa1homeobox A10.439
Smad1MAD homolog 1 (Drosophila)0.430
Lhx1LIM homeobox protein 10.422
Lef1lymphoid enhancer binding factor 10.401
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.389
Acvr1activin A receptor, type 10.387
Hspg2perlecan (heparan sulfate proteoglycan 2)0.383
Rac1RAS-related C3 botulinum substrate 10.380
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.341
Gas1growth arrest specific 10.339
Alx4aristaless-like homeobox 40.336
Slit2slit homolog 2 (Drosophila)0.330
Foxa2forkhead box A20.329
Psen1presenilin 10.327
Wnt3awingless-related MMTV integration site 3A0.320
Sox9SRY-box containing gene 90.310
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.292
Eya1eyes absent 1 homolog (Drosophila)0.291
Chd7chromodomain helicase DNA binding protein 70.279
Ptk7PTK7 protein tyrosine kinase 70.279
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.277
Hoxd13homeobox D130.275
Tbx2T-box 20.273
Dlg1discs, large homolog 1 (Drosophila)0.271
Shesrc homology 2 domain-containing transforming protein E0.269
Twsg1twisted gastrulation homolog 1 (Drosophila)0.264
Twist2twist homolog 2 (Drosophila)0.250
Robo2roundabout homolog 2 (Drosophila)0.246
Fzd1frizzled homolog 1 (Drosophila)0.240
Gbx2gastrulation brain homeobox 20.240
Emx2empty spiracles homolog 2 (Drosophila)0.237
Prrx2paired related homeobox 20.236
Hoxa10homeobox A100.232
Prdm1PR domain containing 1, with ZNF domain0.230
Tcf21transcription factor 210.225
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
tbx1T-box 10.994
wnt11wingless-type MMTV integration site family, member 110.987
ntlano tail a0.963
bmpr1aabone morphogenetic protein receptor, type 1aa0.952
gli2aGLI-Kruppel family member GLI2a0.917
itgb1bintegrin, beta 1b0.905
itgavintegrin, alpha V0.898
spry4sprouty (Drosophila) homolog 40.869
fgfr1afibroblast growth factor receptor 1a0.866
fgf3fibroblast growth factor 30.860
bmp4bone morphogenetic protein 40.839
spns2spinster homolog 2 (Drosophila)0.827
fbln1fibulin 10.826
oepone-eyed pinhead0.816
runx2brunt-related transcription factor 2b0.806
her1hairy-related 10.796
wnt5bwingless-type MMTV integration site family, member 5b0.773
tbx20T-box 200.748
gna12guanine nucleotide binding protein (G protein) alpha 120.748
ndr2nodal-related 20.739
eomesaeomesodermin homolog a0.724
wnt4awingless-type MMTV integration site family, member 4a0.705
cxcr4achemokine (C-X-C motif) receptor 4a0.680
fn1fibronectin 10.656
has2hyaluronan synthase 20.642
mmp2matrix metalloproteinase 20.639
tbx16T-box gene 160.631
flhfloating head0.629
cntn2contactin 20.623
ventventral expressed homeobox0.614
bmp2abone morphogenetic protein 2a0.609
dlx2adistal-less homeobox gene 2a0.593
hnf1baHNF1 homeobox Ba0.592
tll1tolloid-like 10.592
mapk1mitogen-activated protein kinase 10.575
itgb1b.2integrin, beta 1b.20.566
vedventrally expressed dharma/bozozok antagonist0.535
meis2.1myeloid ecotropic viral integration site 2.10.533
bmp2bbone morphogenetic protein 2b0.523
ephb4beph receptor B4b0.522
sox32SRY-box containing gene 320.521
gli1GLI-Kruppel family member 10.514
nkd2naked cuticle homolog 2 and naked 2a0.502
map2k4amitogen-activated protein kinase kinase 4a0.499
smad9MAD homolog 9 (Drosophila)0.485
bonbonnie and clyde0.483
alcambactivated leukocyte cell adhesion molecule b0.468
nkx2.5NK2 transcription factor related 50.462
krml2.2Kreisler (mouse) maf-related leucine zipper homolog 2.20.461
nrg2aneuregulin 2a0.451
emx3empty spiracles homeobox 30.447
igf1rbinsulin-like growth factor 1b receptor0.447
krit1KRIT1, ankyrin repeat containing0.438
lfnglunatic fringe homolog0.432
wnt9bwingless-type MMTV integration site family, member 9B0.426
efnb3bephrin B3b0.424
foxp1bforkhead box P1b0.419
slit3slit (Drosophila) homolog 30.398
mapk3mitogen-activated protein kinase 30.391
chsy1chondroitin sulfate synthase 10.385
nkx1.2laNK1 transcription factor related 2-like,a0.372
wnt9awingless-type MMTV integration site family, member 9A0.372
gro1groucho 10.372
bmpr2bbone morphogenetic protein receptor, type II b (serine/threonine kinase)0.369
rbm22RNA binding motif protein 220.369
sulf1sulfatase 10.367
gna13bguanine nucleotide binding protein (G protein), alpha 13b0.362
vcanaversican a0.361
hey2hairy/enhancer-of-split related with YRPW motif 20.353
crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.350
tbx2bT-box 2b0.345
egr1early growth response 10.335
nkd1naked cuticle homolog 1 (Drosophila)0.332
hoxa13bhomeo box A13b0.329
lppLIM domain containing preferred translocation partner in lipoma0.329
robo3roundabout homolog 30.321
smad5MAD homolog 5 (Drosophila)0.321
wnt2bbwingless-type MMTV integration site family, member 2Bb0.320
shhasonic hedgehog a0.316
ets1av-ets erythroblastosis virus E26 oncogene homolog 1a0.309
ptprcprotein tyrosine phosphatase, receptor type, C0.309
six4bsine oculis homeobox homolog 4b0.309
plxnb2aplexin b2a0.304
etv2ets variant gene 20.297
msxcmuscle segment homeobox C0.294
nr2e3nuclear receptor subfamily 2, group E, member 30.292
efnb2aephrin B2a0.287
sox2SRY-box containing gene 20.274
kdrlkinase insert domain receptor like0.274
ptch1patched 10.269
snai1bsnail homolog 1b (Drosophila)0.269
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
stumpsCG31317 gene product from transcript CG31317-RC0.775
Rac1CG2248 gene product from transcript CG2248-RA0.617
wbwing blister0.287
MadMothers against dpp0.225
Rho1CG8416 gene product from transcript CG8416-RB0.206
par-1CG8201 gene product from transcript CG8201-RA0.175
eyaeyes absent0.171
Wnt5Wnt oncogene analog 50.158
mewmultiple edematous wings0.143
jebjelly belly0.142
frcfringe connection0.142
emcextra macrochaetae0.129
EgfrEpidermal growth factor receptor0.118
nkdnaked cuticle0.112
robo3CG5423 gene product from transcript CG5423-RA0.112
mbcmyoblast city0.084
gbbglass bottom boat0.078
Fak56DFocal Adhesion Kinase0.076
cicubitus interruptus0.075
CkIIalphaCasein kinase II alpha subunit0.072
fz2frizzled 20.064
McrMacroglobulin complement-related0.063
HmgcrHMG Coenzyme A reductase0.063
LanB2Laminin B20.052
stanstarry night0.048
DscamDown syndrome cell adhesion molecule0.045
Pi3K92ECG4141 gene product from transcript CG4141-RB0.043
AlkCG8250 gene product from transcript CG8250-RA0.043
rawCG12437 gene product from transcript CG12437-RB0.043
fkhfork head0.043
gcmglial cells missing0.041
Rac2CG8556 gene product from transcript CG8556-RA0.041
CG30115CG30115 gene product from transcript CG30115-RE0.039
Wnt4Wnt oncogene analog 40.037
CG10627CG10627 gene product from transcript CG10627-RA0.036
bab2CG9102 gene product from transcript CG9102-RA0.036
argosCG4531 gene product from transcript CG4531-RA0.034
CG14869CG14869 gene product from transcript CG14869-RB0.034
Six4CG3871 gene product from transcript CG3871-RA0.034
TrhTryptophan hydroxylase0.031
LanALaminin A0.031
Traf4TNF-receptor-associated factor 40.030
jingCG9397 gene product from transcript CG9397-RI0.030
LanB1CG7123 gene product from transcript CG7123-RA0.029
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa1.000
FGF1fibroblast growth factor 1 (acidic)0.995
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.994
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.990
FN1fibronectin 10.963
PSEN1presenilin 10.935
EGFRepidermal growth factor receptor0.917
APCadenomatous polyposis coli0.913
PTK2PTK2 protein tyrosine kinase 20.871
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.792
BMPR1Abone morphogenetic protein receptor, type IA0.771
CTNND1catenin (cadherin-associated protein), delta 10.770
PTPN1protein tyrosine phosphatase, non-receptor type 10.764
GSK3Bglycogen synthase kinase 3 beta0.693
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.611
IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor)0.604
SOCS3suppressor of cytokine signaling 30.589
JUPjunction plakoglobin0.567
IQGAP1IQ motif containing GTPase activating protein 10.500
PTPN12protein tyrosine phosphatase, non-receptor type 120.492
SMAD1SMAD family member 10.484
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.464
ARandrogen receptor0.460
IFNAR2interferon (alpha, beta and omega) receptor 20.444
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.428
BCAR1breast cancer anti-estrogen resistance 10.421
JAK2Janus kinase 20.416
ROD1ROD1 regulator of differentiation 1 (S. pombe)0.405
ATN1atrophin 10.355
BAIAP2BAI1-associated protein 20.340
TCF7L2transcription factor 7-like 2 (T-cell specific, HMG-box)0.335
BMP1bone morphogenetic protein 10.325
GLIS2GLIS family zinc finger 20.320
TCF4transcription factor 40.318
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.293
QKIquaking homolog, KH domain RNA binding (mouse)0.292
STAT5Asignal transducer and activator of transcription 5A0.275
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.273
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.270
FGF10fibroblast growth factor 100.264
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.226
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein0.204
IFNGR1interferon gamma receptor 10.196
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.190
SMAD3SMAD family member 30.186
LRRK2leucine-rich repeat kinase 20.184
DKK1dickkopf homolog 1 (Xenopus laevis)0.179
LATlinker for activation of T cells0.172
CAPRIN2caprin family member 20.158
CAPN1calpain 1, (mu/I) large subunit0.158
BTRCbeta-transducin repeat containing0.154
FBLN1fibulin 10.154
FERMT2fermitin family member 20.146
CTGFconnective tissue growth factor0.143
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.141
IRS1insulin receptor substrate 10.141
ZNF585Bzinc finger protein 585B0.137
STAT2signal transducer and activator of transcription 2, 113kDa0.137
IFNAR1interferon (alpha, beta and omega) receptor 10.137
TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)0.136
DPP4dipeptidyl-peptidase 40.135
TLN1talin 10.134
RAB8BRAB8B, member RAS oncogene family0.125
CDH2cadherin 2, type 1, N-cadherin (neuronal)0.125
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.121
THBS1thrombospondin 10.119
ERBB2IPerbb2 interacting protein0.118
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.117
MAP3K5mitogen-activated protein kinase kinase kinase 50.116
CD74CD74 molecule, major histocompatibility complex, class II invariant chain0.114
ZMYND11zinc finger, MYND-type containing 110.110
INADLInaD-like (Drosophila)0.109
SOS1son of sevenless homolog 1 (Drosophila)0.108
SCYL2SCY1-like 2 (S. cerevisiae)0.106
RBFOX1RNA binding protein, fox-1 homolog (C. elegans) 10.105
HSPG2heparan sulfate proteoglycan 20.103
IGF1Rinsulin-like growth factor 1 receptor0.102
SMURF1SMAD specific E3 ubiquitin protein ligase 10.100
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.097
TUBB2Atubulin, beta 2A0.096
AXIN1axin 10.093
SMURF2SMAD specific E3 ubiquitin protein ligase 20.092
SNX9sorting nexin 90.091
ACTN4actinin, alpha 40.091
AMMECR1Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 10.089
PTPRJprotein tyrosine phosphatase, receptor type, J0.088
SMAD2SMAD family member 20.088
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.087
GIGYF1GRB10 interacting GYF protein 10.086
NEDD4neural precursor cell expressed, developmentally down-regulated 40.085
LIMK1LIM domain kinase 10.084
FLNBfilamin B, beta0.083
JAG2jagged 20.083
LTBP4latent transforming growth factor beta binding protein 40.082
CTNNBIP1catenin, beta interacting protein 10.082
WNT3Awingless-type MMTV integration site family, member 3A0.082
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism