The network for 'proteasome assembly' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

proteasome assembly

The aggregation, arrangement and bonding together of a mature, active proteasome complex.

NameDescriptionProbabilityFunc Analog Organism
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.997
Psma7proteasome (prosome, macropain) subunit, alpha type 70.982
Psma4proteasome (prosome, macropain) subunit, alpha type 40.972
Psma2proteasome (prosome, macropain) subunit, alpha type 20.945
Psmb7proteasome (prosome, macropain) subunit, beta type 70.833
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.825
Psmb6proteasome (prosome, macropain) subunit, beta type 60.800
Psmc3proteasome (prosome, macropain) 26S subunit, ATPase 30.790
Psmd6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.663
Psma5proteasome (prosome, macropain) subunit, alpha type 50.662
Iqcb1IQ calmodulin-binding motif containing 10.626
Psma1proteasome (prosome, macropain) subunit, alpha type 10.508
Rpgrip1lRpgrip1-like0.425
Pompproteasome maturation protein0.403
Hspa8heat shock protein 80.354
Psmb4proteasome (prosome, macropain) subunit, beta type 40.317
Cct7chaperonin containing Tcp1, subunit 7 (eta)0.304
Psmd14proteasome (prosome, macropain) 26S subunit, non-ATPase, 140.297
Vcpvalosin containing protein0.271
Psmc5protease (prosome, macropain) 26S subunit, ATPase 50.268
Nedd8neural precursor cell expressed, developmentally down-regulated gene 80.244
Psmb5proteasome (prosome, macropain) subunit, beta type 50.242
Nphp4nephronophthisis 4 (juvenile) homolog (human)0.209
Psma6proteasome (prosome, macropain) subunit, alpha type 60.208
Polr2gpolymerase (RNA) II (DNA directed) polypeptide G0.203
Psma3proteasome (prosome, macropain) subunit, alpha type 30.170
Psmb3proteasome (prosome, macropain) subunit, beta type 30.165
Psmd12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.155
Cct3chaperonin containing Tcp1, subunit 3 (gamma)0.134
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.130
Psmb2proteasome (prosome, macropain) subunit, beta type 20.095
Cct8chaperonin containing Tcp1, subunit 8 (theta)0.086
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.082
Cct5chaperonin containing Tcp1, subunit 5 (epsilon)0.082
Tbcbtubulin folding cofactor B0.077
Cdc123cell division cycle 123 homolog (S. cerevisiae)0.071
Bzw1basic leucine zipper and W2 domains 10.069
Gtf2e2general transcription factor II E, polypeptide 2 (beta subunit)0.067
H2-Ke2H2-K region expressed gene 20.066
Parlpresenilin associated, rhomboid-like0.064
Emg1EMG1 nucleolar protein homolog (S. cerevisiae)0.062
Psmd13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.062
Cops5COP9 (constitutive photomorphogenic) homolog, subunit 5 (Arabidopsis thaliana)0.061
Sec13SEC13 homolog (S. cerevisiae)0.059
Smu1smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)0.058
Chmp2achromatin modifying protein 2A0.056
Aimp1aminoacyl tRNA synthetase complex-interacting multifunctional protein 10.054
Cops4COP9 (constitutive photomorphogenic) homolog, subunit 4 (Arabidopsis thaliana)0.054
2900010J23RikRIKEN cDNA 2900010J23 gene0.054
Nphp1nephronophthisis 1 (juvenile) homolog (human)0.048
Banf1barrier to autointegration factor 10.044
Hsph1heat shock 105kDa/110kDa protein 10.043
Hax1HCLS1 associated X-10.042
Mrps18bmitochondrial ribosomal protein S18B0.042
Hspa5heat shock protein 50.042
Psmd10proteasome (prosome, macropain) 26S subunit, non-ATPase, 100.040
Psmc4proteasome (prosome, macropain) 26S subunit, ATPase, 40.040
Pno1partner of NOB1 homolog (S. cerevisiae)0.039
Chordc1cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 10.037
Uba3ubiquitin-like modifier activating enzyme 30.035
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.035
Hspe1heat shock protein 1 (chaperonin 10)0.035
Psmd3proteasome (prosome, macropain) 26S subunit, non-ATPase, 30.031
Cacybpcalcyclin binding protein0.028
Ppa1pyrophosphatase (inorganic) 10.027
Stip1stress-induced phosphoprotein 10.027
Prdx1peroxiredoxin 10.025
Erhenhancer of rudimentary homolog (Drosophila)0.025
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.023
0610009D07RikRIKEN cDNA 0610009D07 gene0.023
Pfdn2prefoldin 20.022
Glod4glyoxalase domain containing 40.021
Exosc7exosome component 70.021
Mrpl18mitochondrial ribosomal protein L180.020
Csnk2bcasein kinase 2, beta polypeptide0.019
NmiN-myc (and STAT) interactor0.019
Mrps22mitochondrial ribosomal protein S220.019
Pin1protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 10.017
Ormdl1ORM1-like 1 (S. cerevisiae)0.017
Fkbp4FK506 binding protein 40.016
1810009A15RikRIKEN cDNA 1810009A15 gene0.016
Pak1ip1PAK1 interacting protein 10.015
Prpf40aPRP40 pre-mRNA processing factor 40 homolog A (yeast)0.015
Hnrnpfheterogeneous nuclear ribonucleoprotein F0.015
Hspd1heat shock protein 1 (chaperonin)0.015
Manfmesencephalic astrocyte-derived neurotrophic factor0.015
Gm10094predicted gene 100940.014
Psmd1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.014
Grpel1GrpE-like 1, mitochondrial0.014
Bud31BUD31 homolog (yeast)0.014
Psmd8proteasome (prosome, macropain) 26S subunit, non-ATPase, 80.014
Eif2s1eukaryotic translation initiation factor 2, subunit 1 alpha0.014
Orc4origin recognition complex, subunit 40.013
Hspa4heat shock protein 40.013
Dnaja1DnaJ (Hsp40) homolog, subfamily A, member 10.013
l7Rn6lethal, Chr 7, Rinchik 60.013
Snf8SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)0.013
Magohmago-nashi homolog, proliferation-associated (Drosophila)0.013
Dscaml1Down syndrome cell adhesion molecule-like 10.012
Ubxn1UBX domain protein 10.012
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
pbs-2Protein PBS-20.643
rpn-7Protein RPN-70.637
rpn-10Protein RPN-100.493
rpn-5Protein RPN-50.267
pas-6Protein PAS-60.249
tba-2Protein TBA-20.199
rpn-3Protein RPN-30.151
csr-1Protein CSR-10.147
pas-1Protein PAS-10.138
rpt-3Protein RPT-30.134
pbs-1Protein PBS-10.121
pbs-6Protein PBS-60.112
rpt-5Protein RPT-50.104
tbb-1Protein TBB-10.091
par-5Protein PAR-50.089
pbs-5Protein PBS-50.071
pas-7Protein PAS-70.068
rpn-1Protein RPN-10.065
rpn-2Protein RPN-20.058
cdc-48.1Protein CDC-48.10.055
usp-14Protein USP-140.052
pas-2Protein PAS-20.048
pas-4Protein PAS-40.046
cdc-48.2Protein CDC-48.20.046
cgh-1Protein CGH-10.046
rpt-4Protein RPT-40.041
rpt-2Protein RPT-20.028
F42A10.5Protein F42A10.50.027
npl-4.1Protein NPL-4.10.024
ZC395.10Protein ZC395.100.022
cct-6Protein CCT-60.022
cee-1Protein CEE-10.018
npp-15Protein NPP-150.017
F32D1.5Protein F32D1.50.017
rpl-11.1Protein RPL-11.10.016
cct-4Protein CCT-40.016
uba-1Protein UBA-10.016
rpn-12Protein RPN-120.014
wdfy-2Protein WDFY-20.014
CELE_C01G10.8Protein C01G10.80.014
pbs-4Protein PBS-40.014
rpt-6Protein RPT-60.014
nduf-2.2Protein NDUF-2.20.013
C56G2.7Protein C56G2.70.013
rpn-9Protein RPN-90.012
tba-1Protein TBA-10.012
pgl-1Protein PGL-10.012
W03G9.3Protein W03G9.30.011
rpl-25.2Protein RPL-25.20.010
pfn-1Protein PFN-10.010
map-2Protein MAP-20.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Tbp-1Tat-binding protein-10.848
Rpt4CG3455 gene product from transcript CG3455-RA0.824
Rpn9CG10230 gene product from transcript CG10230-RB0.775
Pros26.4Proteasome 26S subunit subunit 4 ATPase0.743
Pros45CG1489 gene product from transcript CG1489-RA0.659
Rpn11CG18174 gene product from transcript CG18174-RA0.587
Rpn1CG7762 gene product from transcript CG7762-RA0.494
Rpn6Proteasome p44.5 subunit0.455
CG5384CG5384 gene product from transcript CG5384-RA0.452
Rpt3CG16916 gene product from transcript CG16916-RA0.393
Rpt1CG1341 gene product from transcript CG1341-RA0.327
Mov34CG3416 gene product from transcript CG3416-RA0.308
CG13349CG13349 gene product from transcript CG13349-RA0.289
CG12321CG12321 gene product from transcript CG12321-RA0.243
Pros28.1Proteasome 28kD subunit 10.139
Prosbeta3Proteasome beta3 subunit0.124
Pros35Proteasome 35kD subunit0.113
Rpn7CG5378 gene product from transcript CG5378-RA0.113
Prosbeta1Proteasome beta1 subunit0.069
Pros25Proteasome 25kD subunit0.061
Rpn5CG1100 gene product from transcript CG1100-RA0.056
Rpn3Regulatory particle non-ATPase 30.046
Prosbeta7Proteasome beta7 subunit0.037
Rpn12CG4157 gene product from transcript CG4157-RA0.033
Uba1Ubiquitin activating enzyme 10.026
Rpn2CG11888 gene product from transcript CG11888-RA0.025
p47CG11139 gene product from transcript CG11139-RA0.024
Atg6Autophagy-specific gene 60.020
mrimrityu0.019
Prosbeta2Proteasome beta2 subunit0.016
CG2046CG2046 gene product from transcript CG2046-RA0.016
CG3223CG3223 gene product from transcript CG3223-RA0.015
CG10435CG10435 gene product from transcript CG10435-RA0.014
matsmob as tumor suppressor0.012
CG6410CG6410 gene product from transcript CG6410-RA0.012
CG1599CG1599 gene product from transcript CG1599-RA0.012
CG7668CG7668 gene product from transcript CG7668-RA0.011
CG5902CG5902 gene product from transcript CG5902-RB0.011
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.995
PSMC1proteasome (prosome, macropain) 26S subunit, ATPase, 10.983
PSMA6proteasome (prosome, macropain) subunit, alpha type, 60.978
PSMC5proteasome (prosome, macropain) 26S subunit, ATPase, 50.969
PSMA2proteasome (prosome, macropain) subunit, alpha type, 20.951
PSMC3proteasome (prosome, macropain) 26S subunit, ATPase, 30.948
PSMB7proteasome (prosome, macropain) subunit, beta type, 70.944
PSMD6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.939
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 140.937
PSMB2proteasome (prosome, macropain) subunit, beta type, 20.931
PSMB4proteasome (prosome, macropain) subunit, beta type, 40.912
PSMA1proteasome (prosome, macropain) subunit, alpha type, 10.895
PSMC2proteasome (prosome, macropain) 26S subunit, ATPase, 20.888
PSMA3proteasome (prosome, macropain) subunit, alpha type, 30.863
PSMC4proteasome (prosome, macropain) 26S subunit, ATPase, 40.846
PSMD2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.816
PSMD7proteasome (prosome, macropain) 26S subunit, non-ATPase, 70.807
PSMD1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.802
PSMC6proteasome (prosome, macropain) 26S subunit, ATPase, 60.773
PSMA7proteasome (prosome, macropain) subunit, alpha type, 70.742
PSMD11proteasome (prosome, macropain) 26S subunit, non-ATPase, 110.740
PSMB1proteasome (prosome, macropain) subunit, beta type, 10.729
PSMA5proteasome (prosome, macropain) subunit, alpha type, 50.717
PSMB5proteasome (prosome, macropain) subunit, beta type, 50.657
PSMD13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.597
HSP90AB1heat shock protein 90kDa alpha (cytosolic), class B member 10.591
PSMA4proteasome (prosome, macropain) subunit, alpha type, 40.549
PSMB6proteasome (prosome, macropain) subunit, beta type, 60.299
PSMB3proteasome (prosome, macropain) subunit, beta type, 30.268
PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 80.225
RAD23BRAD23 homolog B (S. cerevisiae)0.198
UCHL5ubiquitin carboxyl-terminal hydrolase L50.140
PSME2proteasome (prosome, macropain) activator subunit 2 (PA28 beta)0.110
PSMD10proteasome (prosome, macropain) 26S subunit, non-ATPase, 100.105
PSMD12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.091
PSMD3proteasome (prosome, macropain) 26S subunit, non-ATPase, 30.072
POMPproteasome maturation protein0.062
USP14ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)0.051
TERF1telomeric repeat binding factor (NIMA-interacting) 10.016
PSME1proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)0.016
PSMB10proteasome (prosome, macropain) subunit, beta type, 100.015
PSMG2proteasome (prosome, macropain) assembly chaperone 20.015
SHFM1split hand/foot malformation (ectrodactyly) type 10.014
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
RPN2Rpn2p0.933
RPT6Rpt6p0.716
RPT3Rpt3p0.647
RPN10Rpn10p0.641
RPN1Rpn1p0.567
RPT4Rpt4p0.419
RPN9Rpn9p0.301
RPN6Rpn6p0.278
RPT5Rpt5p0.272
RPN14Rpn14p0.269
RPN3Rpn3p0.247
UMP1Ump1p0.241
RPN12Rpn12p0.220
RPT1Rpt1p0.160
HSM3Hsm3p0.156
PRE8Pre8p0.115
RPN13Rpn13p0.114
NAS2Nas2p0.107
PRE6Pre6p0.095
ECM29Ecm29p0.094
PRE10Pre10p0.090
PRE2Pre2p0.076
RPT2Rpt2p0.066
PRE1Pre1p0.062
RPN5Rpn5p0.060
RPN7Rpn7p0.057
STI1Sti1p0.056
SEM1Sem1p0.056
PDC6Pdc6p0.051
PRE5Pre5p0.049
SUI1Sui1p0.046
CYC7Cyc7p0.044
VMA1Vma1p0.037
PRE7Pre7p0.037
PBA1Pba1p0.036
PFS1Pfs1p0.034
ARO10Aro10p0.034
PIB1Pib1p0.033
RPN8Rpn8p0.032
PUP2Pup2p0.031
TSC3Tsc3p0.030
LCB2Lcb2p0.030
ADY2Ady2p0.029
SRD1Srd1p0.028
YLR264C-Ahypothetical protein0.028
YNL217Whypothetical protein0.027
VMA13Vma13p0.027
ENA5Ena5p0.026
NAS6Nas6p0.026
IRA1Ira1p0.026
YLR162Whypothetical protein0.025
LEU2Leu2p0.025
YOL038C-Ahypothetical protein0.025
FMP52Fmp52p0.025
YAR068Whypothetical protein0.025
BTN2Btn2p0.024
ALG13Alg13p0.024
HXT3Hxt3p0.023
ARP10Arp10p0.023
SCL1Scl1p0.023
HSC82Hsc82p0.023
ADH2Adh2p0.022
MF(ALPHA)2Mf(alpha)2p0.022
ENA1Ena1p0.022
MER1Mer1p0.022
CHA1Cha1p0.022
YLR042Chypothetical protein0.022
YAR066Whypothetical protein0.022
PTR2Ptr2p0.021
PUP3Pup3p0.021
URA3Ura3p0.021
JLP2Jlp2p0.021
UBC13Ubc13p0.021
PUP1Pup1p0.021
ZPS1Zps1p0.020
URA2Ura2p0.020
FAA2Faa2p0.020
UBP11Ubp11p0.020
YPR157Whypothetical protein0.020
YIR035Chypothetical protein0.020
TIP1Tip1p0.020
YLR290Chypothetical protein0.020
AUA1Aua1p0.020
YLR040Chypothetical protein0.020
ARO9Aro9p0.020
UFD4Ufd4p0.020
PDC5Pdc5p0.020
SGT2Sgt2p0.020
CUP1-1Cup1-1p0.020
PBP4Pbp4p0.020
HPF1Hpf1p0.019
ATP6Atp6p0.019
HUL5Hul5p0.019
SPL2Spl2p0.019
LTV1Ltv1p0.019
YBR013Chypothetical protein0.019
REE1Ree1p0.019
MF(ALPHA)1Mf(alpha)1p0.019
MRH1Mrh1p0.019
YKR075Chypothetical protein0.019