The network for 'positive regulation of tolerance induction' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of tolerance induction

Any process that activates or increases the frequency, rate, or extent of tolerance induction.

NameDescriptionProbabilityFunc Analog Organism
Traf6TNF receptor-associated factor 60.929
Tgfbr1transforming growth factor, beta receptor I0.733
Tgfbr2transforming growth factor, beta receptor II0.650
Smad4MAD homolog 4 (Drosophila)0.441
H2-D1histocompatibility 2, D region locus 10.330
Myd88myeloid differentiation primary response gene 880.277
H2-Q7histocompatibility 2, Q region locus 70.251
Shc1src homology 2 domain-containing transforming protein C10.197
Smad6MAD homolog 6 (Drosophila)0.180
Map3k7mitogen-activated protein kinase kinase kinase 70.132
TapbpTAP binding protein0.103
B2mbeta-2 microglobulin0.070
Bmpr1abone morphogenetic protein receptor, type 1A0.055
H2-Q6histocompatibility 2, Q region locus 60.048
Smad7MAD homolog 7 (Drosophila)0.048
H2-K1histocompatibility 2, K1, K region0.045
Engendoglin0.043
Dicer1Dicer1, Dcr-1 homolog (Drosophila)0.041
Cd3dCD3 antigen, delta polypeptide0.038
Ece1endothelin converting enzyme 10.035
Efemp2epidermal growth factor-containing fibulin-like extracellular matrix protein 20.035
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.034
Rnf11ring finger protein 110.031
Smad1MAD homolog 1 (Drosophila)0.031
Irak4interleukin-1 receptor-associated kinase 40.031
Cyldcylindromatosis (turban tumor syndrome)0.030
Dvl1dishevelled, dsh homolog 1 (Drosophila)0.030
Prkg1protein kinase, cGMP-dependent, type I0.028
Atp7aATPase, Cu++ transporting, alpha polypeptide0.027
Kiss1KiSS-1 metastasis-suppressor0.025
Ptpn11protein tyrosine phosphatase, non-receptor type 110.025
Grb2growth factor receptor bound protein 20.022
H2-Q8histocompatibility 2, Q region locus 80.021
Foxp1forkhead box P10.020
Acvr1activin A receptor, type 10.020
Cdh5cadherin 50.020
Vegfavascular endothelial growth factor A0.019
Pthlhparathyroid hormone-like peptide0.019
Gnaqguanine nucleotide binding protein, alpha q polypeptide0.018
Stat3signal transducer and activator of transcription 30.018
Cd3gCD3 antigen, gamma polypeptide0.017
Kif19akinesin family member 19A0.016
Tax1bp1Tax1 (human T-cell leukemia virus type I) binding protein 10.015
Grb10growth factor receptor bound protein 100.015
Bptfbromodomain PHD finger transcription factor0.014
Sh2d2aSH2 domain protein 2A0.014
Smurf1SMAD specific E3 ubiquitin protein ligase 10.013
Hipk3homeodomain interacting protein kinase 30.013
Tmem64transmembrane protein 640.013
Mkl2MKL/myocardin-like 20.012
Sox9SRY-box containing gene 90.012
Agtr1aangiotensin II receptor, type 1a0.012
Tlr4toll-like receptor 40.011
Ticam1toll-like receptor adaptor molecule 10.011
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.011
Cpdcarboxypeptidase D0.011
Cd8b1CD8 antigen, beta chain 10.011
Cited2Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 20.011
Ednraendothelin receptor type A0.010
Cd6CD6 antigen0.010
Erbb2ipErbb2 interacting protein0.010
CblCasitas B-lineage lymphoma0.010
Kif3akinesin family member 3A0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
B2Mbeta-2-microglobulin0.995
HLA-Cmajor histocompatibility complex, class I, C0.994
HLA-Gmajor histocompatibility complex, class I, G0.974
HLA-Fmajor histocompatibility complex, class I, F0.910
HLA-Amajor histocompatibility complex, class I, A0.893
HLA-Bmajor histocompatibility complex, class I, B0.736
HLA-Emajor histocompatibility complex, class I, E0.694
LILRA6leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 60.203
LILRB1leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 10.114
ZAP70zeta-chain (TCR) associated protein kinase 70kDa0.060
LCKlymphocyte-specific protein tyrosine kinase0.053
PILRApaired immunoglobin-like type 2 receptor alpha0.045
CD247CD247 molecule0.043
LILRB2leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 20.042
PTPN22protein tyrosine phosphatase, non-receptor type 22 (lymphoid)0.034
IFITM2interferon induced transmembrane protein 2 (1-8D)0.027
TAPBPTAP binding protein (tapasin)0.025
PTPN6protein tyrosine phosphatase, non-receptor type 60.023
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.023
CD14CD14 molecule0.022
LILRA2leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 20.019
IRAK2interleukin-1 receptor-associated kinase 20.018
TPP1tripeptidyl peptidase I0.018
SGK3serum/glucocorticoid regulated kinase family, member 30.017
HK3hexokinase 3 (white cell)0.017
PTAFRplatelet-activating factor receptor0.016
TAP1transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)0.015
GRNgranulin0.015
IFITM3interferon induced transmembrane protein 3 (1-8U)0.014
PSAPprosaposin0.014
TGFB3transforming growth factor, beta 30.014
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.013
BTN3A2butyrophilin, subfamily 3, member A20.013
IRAK1interleukin-1 receptor-associated kinase 10.012
IKZF3IKAROS family zinc finger 3 (Aiolos)0.012
LILRA1leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 10.012
LILRA3leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 30.012
SIGLEC7sialic acid binding Ig-like lectin 70.011
TREM1triggering receptor expressed on myeloid cells 10.011
NEDD9neural precursor cell expressed, developmentally down-regulated 90.011
FSTL1follistatin-like 10.010
TAPBPLTAP binding protein-like0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
RT1-EC2RT1 class Ib, locus EC21.000
RT1-CE12RT1 class I, locus CE120.918
RT1-S3RT1 class Ib, locus S30.676
Psmb9proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)0.575
Irf7interferon regulatory factor 70.502
LOC100364500RT1 class I, locus CE11-like0.485
B2mbeta-2 microglobulin0.480
Lgals9lectin, galactoside-binding, soluble, 90.445
Psmb8proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)0.384
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.186
Oas1a2'-5' oligoadenylate synthetase 1A0.167
Metmet proto-oncogene0.139
RT1-M3-1RT1 class Ib, locus M3, gene 10.138
Kmokynurenine 3-monooxygenase (kynurenine 3-hydroxylase)0.121
Ifi35interferon-induced protein 350.117
Olr837olfactory receptor 8370.117
RT1-N3RT1 class Ib, locus N30.110
Sorbs1sorbin and SH3 domain containing 10.104
Olr37olfactory receptor 370.094
Dock8dedicator of cytokinesis 80.090
Cxcl10chemokine (C-X-C motif) ligand 100.087
Calcrlcalcitonin receptor-like0.086
RT1-CE5RT1 class I, locus CE50.082
Cxcl9chemokine (C-X-C motif) ligand 90.082
Irf1interferon regulatory factor 10.075
RT1-ClRT1 class Ib, locus Cl0.075
Slco2a1solute carrier organic anion transporter family, member 2a10.074
Capn5calpain 50.071
F9coagulation factor IX0.068
LOC100365106rCG32755-like0.067
Foxc2forkhead box C20.056
Rsad2radical S-adenosyl methionine domain containing 20.055
Shc3SHC (Src homology 2 domain containing) transforming protein 30.055
Lgals5lectin, galactose binding, soluble 50.052
Cd37CD37 molecule0.049
Arntaryl hydrocarbon receptor nuclear translocator0.049
Mx1myxovirus (influenza virus) resistance 10.049
Parp14poly (ADP-ribose) polymerase family, member 140.048
Lgals3bplectin, galactoside-binding, soluble, 3 binding protein0.046
Cyp2c23cytochrome P450, family 2, subfamily c, polypeptide 230.046
Anpepalanyl (membrane) aminopeptidase0.043
Hfehemochromatosis0.042
RT1-CE16RT1 class I, locus CE160.041
Stat1signal transducer and activator of transcription 10.039
Gbp2guanylate binding protein 20.039
Hnf4ahepatocyte nuclear factor 4, alpha0.038
Clic4chloride intracellular channel 40.037
Trim47tripartite motif-containing 470.036
Sardhsarcosine dehydrogenase0.036
Fcgr3aFc fragment of IgG, low affinity IIIa, receptor0.036
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.036
Cybacytochrome b-245, alpha polypeptide0.035
Igtpinterferon gamma induced GTPase0.034
Tap1transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)0.034
Ccl5chemokine (C-C motif) ligand 50.033
Itga6integrin, alpha 60.033
Adam10ADAM metallopeptidase domain 100.032
LOC100360587hypothetical protein LOC1003605870.032
Sod3superoxide dismutase 3, extracellular0.032
Pparaperoxisome proliferator activated receptor alpha0.031
Otcornithine carbamoyltransferase0.031
Rbm5RNA binding motif protein 50.030
Bmp6bone morphogenetic protein 60.030
Bst2bone marrow stromal cell antigen 20.029
Man2b1mannosidase, alpha, class 2B, member 10.029
Galr3galanin receptor 30.029
Plbd2phospholipase B domain containing 20.028
Tap2transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)0.027
Ugt1a7cUDP glucuronosyltransferase 1 family, polypeptide A7C0.027
Parp9poly (ADP-ribose) polymerase family, member 90.027
TapbpTAP binding protein0.025
RT1-CE2RT1 class I, locus CE20.024
Elf1E74-like factor 10.024
Cyp2b3cytochrome P450, family 2, subfamily b, polypeptide 30.023
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.023
C8bcomplement component 8, beta polypeptide0.023
Rtp4receptor (chemosensory) transporter protein 40.022
Tgfbr2transforming growth factor, beta receptor II0.022
Cyp2f4cytochrome P450, family 2, subfamily f, polypeptide 40.022
Slc22a18solute carrier family 22, member 180.022
Gbp5guanylate binding protein 50.022
Plgplasminogen0.021
Il8rainterleukin 8 receptor, alpha0.021
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.020
Tnfaip2tumor necrosis factor, alpha-induced protein 20.020
Mgat1mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase0.020
Akr1c14aldo-keto reductase family 1, member C140.020
RT1-M6-2RT1 class I, locus M6, gene 20.020
Oclnoccludin0.020
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.020
Cd4Cd4 molecule0.020
RT1-CE4RT1 class I, locus CE40.020
Itgb5integrin, beta 50.019
Nek9NIMA (never in mitosis gene a)- related kinase 90.019
RT1-BaRT1 class II, locus Ba0.019
RT1-CE15RT1 class I, locus CE150.018
Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 10.018
Oasl22'-5' oligoadenylate synthetase-like 20.018
Ctshcathepsin H0.018
Slco2b1solute carrier organic anion transporter family, member 2b10.018
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism