The network for 'septum primum development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

septum primum development

The progression of the septum primum over time, from its formation to the mature structure.

NameDescriptionProbabilityFunc Analog Organism
Gata4GATA binding protein 41.000
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)1.000
Jag1jagged 10.999
Fgf8fibroblast growth factor 80.998
Isl1ISL1 transcription factor, LIM/homeodomain0.996
Hand2heart and neural crest derivatives expressed transcript 20.995
Fgfr2fibroblast growth factor receptor 20.995
Tgfb2transforming growth factor, beta 20.994
Pax3paired box gene 30.991
Tcfap2atranscription factor AP-2, alpha0.986
Pitx2paired-like homeodomain transcription factor 20.981
Bmp4bone morphogenetic protein 40.974
Hand1heart and neural crest derivatives expressed transcript 10.968
Shhsonic hedgehog0.958
Smosmoothened homolog (Drosophila)0.946
Ptpn11protein tyrosine phosphatase, non-receptor type 110.943
Scn5asodium channel, voltage-gated, type V, alpha0.912
Vegfavascular endothelial growth factor A0.909
Sox4SRY-box containing gene 40.894
Tbx3T-box 30.893
Gata6GATA binding protein 60.893
Nos3nitric oxide synthase 3, endothelial cell0.886
Zfpm2zinc finger protein, multitype 20.850
Rxraretinoid X receptor alpha0.843
Gli3GLI-Kruppel family member GLI30.842
Mesp1mesoderm posterior 10.830
Shesrc homology 2 domain-containing transforming protein E0.827
Meox2mesenchyme homeobox 20.796
Sox7SRY-box containing gene 70.681
Ntf3neurotrophin 30.654
Klf3Kruppel-like factor 3 (basic)0.626
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.623
Fgf3fibroblast growth factor 30.613
Smad6MAD homolog 6 (Drosophila)0.611
Pax6paired box gene 60.610
Foxc2forkhead box C20.601
Tbx5T-box 50.565
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.548
Nf1neurofibromatosis 10.515
Sox18SRY-box containing gene 180.505
Sox9SRY-box containing gene 90.497
Alx4aristaless-like homeobox 40.493
Pcdh12protocadherin 120.491
Pou5f1POU domain, class 5, transcription factor 10.485
Msx1homeobox, msh-like 10.480
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.472
Gja1gap junction protein, alpha 10.452
Hey2hairy/enhancer-of-split related with YRPW motif 20.452
Tbx1T-box 10.444
Tal1T-cell acute lymphocytic leukemia 10.434
Pitx1paired-like homeodomain transcription factor 10.413
Gjb2gap junction protein, beta 20.408
Aplnrapelin receptor0.404
Cldn5claudin 50.399
Prrx1paired related homeobox 10.391
Atoh7atonal homolog 7 (Drosophila)0.385
Foxf1aforkhead box F1a0.365
Ednraendothelin receptor type A0.364
Tcfap2ctranscription factor AP-2, gamma0.360
Bmp2bone morphogenetic protein 20.355
Sox17SRY-box containing gene 170.352
Apcadenomatosis polyposis coli0.346
Col13a1collagen, type XIII, alpha 10.324
Tbx2T-box 20.314
Ptprbprotein tyrosine phosphatase, receptor type, B0.294
Nkx2-3NK2 transcription factor related, locus 3 (Drosophila)0.272
Foxc1forkhead box C10.270
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.255
Tcf15transcription factor 150.249
Gjb6gap junction protein, beta 60.241
Hoxd13homeobox D130.240
Msx2homeobox, msh-like 20.237
Alx3aristaless-like homeobox 30.234
Podxlpodocalyxin-like0.232
Hspg2perlecan (heparan sulfate proteoglycan 2)0.232
Sall4sal-like 4 (Drosophila)0.231
Gpc3glypican 30.227
Ryr2ryanodine receptor 2, cardiac0.226
KelKell blood group0.218
Bmpr1abone morphogenetic protein receptor, type 1A0.215
Ror2receptor tyrosine kinase-like orphan receptor 20.210
Rararetinoic acid receptor, alpha0.209
Kcnq1potassium voltage-gated channel, subfamily Q, member 10.208
Pparaperoxisome proliferator activated receptor alpha0.195
Btbd17BTB (POZ) domain containing 170.193
Fgf10fibroblast growth factor 100.189
Kdrkinase insert domain protein receptor0.186
Foxd2forkhead box D20.182
Thrbthyroid hormone receptor beta0.180
Lef1lymphoid enhancer binding factor 10.174
Fut2fucosyltransferase 20.168
Lrp2low density lipoprotein receptor-related protein 20.155
Alx1ALX homeobox 10.153
Cdh5cadherin 50.150
Efna1ephrin A10.147
Ptpn14protein tyrosine phosphatase, non-receptor type 140.147
Gdnfglial cell line derived neurotrophic factor0.142
Bcl6bB-cell CLL/lymphoma 6, member B0.141
Rasip1Ras interacting protein 10.141
Hcn4hyperpolarization-activated, cyclic nucleotide-gated K+ 40.137
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
FKBP1AFK506 binding protein 1A, 12kDa0.973
TGFB1transforming growth factor, beta 10.970
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.868
BMP2bone morphogenetic protein 20.777
ENGendoglin0.616
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.369
TGFBR1transforming growth factor, beta receptor 10.352
FSTL1follistatin-like 10.333
TGFB3transforming growth factor, beta 30.333
SMAD7SMAD family member 70.293
ACVR1activin A receptor, type I0.233
BMPR1Abone morphogenetic protein receptor, type IA0.178
NRP1neuropilin 10.131
GDF5growth differentiation factor 50.115
MAPK8mitogen-activated protein kinase 80.094
MDC1mediator of DNA-damage checkpoint 10.079
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.061
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.031
TGFBR3transforming growth factor, beta receptor III0.028
ARandrogen receptor0.024
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.022
SMURF2SMAD specific E3 ubiquitin protein ligase 20.017
SMAD2SMAD family member 20.015
BMP4bone morphogenetic protein 40.015
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.015
MARCKSL1MARCKS-like 10.015
SMAD1SMAD family member 10.014
PRKG1protein kinase, cGMP-dependent, type I0.014
CKAP5cytoskeleton associated protein 50.013
NEDD4Lneural precursor cell expressed, developmentally down-regulated 4-like0.012
PDGFCplatelet derived growth factor C0.012
ZMYND11zinc finger, MYND-type containing 110.012
TBX5T-box 50.011
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism