The network for 'regulation of response to reactive oxygen species' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of response to reactive oxygen species

Any process that modulates the frequency, rate or extent of response to reactive oxygen species.

NameDescriptionProbabilityFunc Analog Organism
Apoeapolipoprotein E0.637
Grb10growth factor receptor bound protein 100.290
Tgfbr2transforming growth factor, beta receptor II0.266
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.261
Ece1endothelin converting enzyme 10.238
Gab1growth factor receptor bound protein 2-associated protein 10.214
Cav1caveolin 1, caveolae protein0.205
Fbn1fibrillin 10.166
Ldlrlow density lipoprotein receptor0.155
Elnelastin0.148
Eef1a1eukaryotic translation elongation factor 1 alpha 10.139
Prnpprion protein0.136
Fgfr1fibroblast growth factor receptor 10.134
Prrx1paired related homeobox 10.122
Mitfmicrophthalmia-associated transcription factor0.122
Irs2insulin receptor substrate 20.116
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.108
Mmp2matrix metallopeptidase 20.103
Loxlysyl oxidase0.089
Ghrgrowth hormone receptor0.081
Rps2ribosomal protein S20.079
Acvr1activin A receptor, type 10.072
Vegfavascular endothelial growth factor A0.070
Mt1metallothionein 10.069
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.069
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.068
Fbln5fibulin 50.066
Lrp1low density lipoprotein receptor-related protein 10.055
Rps5ribosomal protein S50.053
Eya1eyes absent 1 homolog (Drosophila)0.051
Smosmoothened homolog (Drosophila)0.047
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.044
Ctsdcathepsin D0.040
Agtr1aangiotensin II receptor, type 1a0.038
Igf2rinsulin-like growth factor 2 receptor0.037
Cyldcylindromatosis (turban tumor syndrome)0.036
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.034
Rps3ribosomal protein S30.033
Adamts1a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10.031
Iduaiduronidase, alpha-L-0.029
Atp7aATPase, Cu++ transporting, alpha polypeptide0.028
Igf2insulin-like growth factor 20.028
Kitkit oncogene0.026
Spna1spectrin alpha 10.026
Agtr2angiotensin II receptor, type 20.025
Col4a5collagen, type IV, alpha 50.025
Abca1ATP-binding cassette, sub-family A (ABC1), member 10.025
Tgfb1transforming growth factor, beta 10.025
Rargretinoic acid receptor, gamma0.024
Edn1endothelin 10.024
Hoxa3homeobox A30.023
Pkd1polycystic kidney disease 1 homolog0.023
Prrx2paired related homeobox 20.021
Cul7cullin 70.020
Col6a1collagen, type VI, alpha 10.020
Ifngr1interferon gamma receptor 10.020
Kitlkit ligand0.018
Ddr2discoidin domain receptor family, member 20.018
Tgfb2transforming growth factor, beta 20.018
Hrh1histamine receptor H10.018
Ageradvanced glycosylation end product-specific receptor0.017
Ltbp2latent transforming growth factor beta binding protein 20.017
Bmp2bone morphogenetic protein 20.017
Vcpvalosin containing protein0.017
Mn1meningioma 10.016
Nr2f2nuclear receptor subfamily 2, group F, member 20.016
Aplp2amyloid beta (A4) precursor-like protein 20.016
Col8a1collagen, type VIII, alpha 10.016
Pax3paired box gene 30.016
Mus81MUS81 endonuclease homolog (yeast)0.015
Thbs2thrombospondin 20.015
Ppargperoxisome proliferator activated receptor gamma0.015
Ywhahtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide0.015
Gaaglucosidase, alpha, acid0.015
Slc12a6solute carrier family 12, member 60.015
Timp3tissue inhibitor of metalloproteinase 30.015
Tenc1tensin like C1 domain-containing phosphatase0.014
S1pr2sphingosine-1-phosphate receptor 20.014
Ptrfpolymerase I and transcript release factor0.014
Rspo2R-spondin 2 homolog (Xenopus laevis)0.014
Tgfbr1transforming growth factor, beta receptor I0.014
Gigyf1GRB10 interacting GYF protein 10.014
Nos3nitric oxide synthase 3, endothelial cell0.014
Thbs1thrombospondin 10.013
Fbln1fibulin 10.013
Trim43atripartite motif-containing 43A0.013
Tgfb1i1transforming growth factor beta 1 induced transcript 10.013
Npc1Niemann Pick type C10.013
Pecam1platelet/endothelial cell adhesion molecule 10.012
Fzd2frizzled homolog 2 (Drosophila)0.012
Timp2tissue inhibitor of metalloproteinase 20.012
Thbs3thrombospondin 30.012
Slc10a6solute carrier family 10 (sodium/bile acid cotransporter family), member 60.012
Sik3SIK family kinase 30.012
Gsk3bglycogen synthase kinase 3 beta0.011
Olfr16olfactory receptor 160.011
Col1a2collagen, type I, alpha 20.011
Lass2LAG1 homolog, ceramide synthase 20.011
Mplmyeloproliferative leukemia virus oncogene0.011
Mkl2MKL/myocardin-like 20.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
EGFRepidermal growth factor receptor0.973
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.893
MAFGv-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)0.604
METmet proto-oncogene (hepatocyte growth factor receptor)0.451
PRDX1peroxiredoxin 10.379
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.279
INSRinsulin receptor0.250
LTBP2latent transforming growth factor beta binding protein 20.249
GAS6growth arrest-specific 60.181
IRS1insulin receptor substrate 10.171
GAB1GRB2-associated binding protein 10.157
SOD1superoxide dismutase 1, soluble0.089
MAPTmicrotubule-associated protein tau0.076
GRB10growth factor receptor-bound protein 100.062
IRS2insulin receptor substrate 20.060
GHRgrowth hormone receptor0.059
APOEapolipoprotein E0.057
FBXO7F-box protein 70.052
RANBP9RAN binding protein 90.050
LATlinker for activation of T cells0.049
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.040
LOXL1lysyl oxidase-like 10.039
ZBED1zinc finger, BED-type containing 10.037
JAK2Janus kinase 20.036
PTPRJprotein tyrosine phosphatase, receptor type, J0.035
PLAURplasminogen activator, urokinase receptor0.034
APOA1apolipoprotein A-I0.034
ADRBK1adrenergic, beta, receptor kinase 10.032
GAB2GRB2-associated binding protein 20.032
DYNLL1dynein, light chain, LC8-type 10.031
IGF1Rinsulin-like growth factor 1 receptor0.031
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.030
MAFFv-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)0.029
PLAUplasminogen activator, urokinase0.028
PLXNB1plexin B10.027
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.026
PLATplasminogen activator, tissue0.026
RAB5BRAB5B, member RAS oncogene family0.024
HGFhepatocyte growth factor (hepapoietin A; scatter factor)0.022
GIT1G protein-coupled receptor kinase interacting ArfGAP 10.021
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.021
ABI2abl-interactor 20.020
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)0.020
FGFR1fibroblast growth factor receptor 10.019
MAP2K6mitogen-activated protein kinase kinase 60.018
ARHGEF12Rho guanine nucleotide exchange factor (GEF) 120.018
WASF1WAS protein family, member 10.017
APOHapolipoprotein H (beta-2-glycoprotein I)0.016
WDR83WD repeat domain 830.016
SNCAIPsynuclein, alpha interacting protein0.016
MAP1Bmicrotubule-associated protein 1B0.015
NOGnoggin0.015
VIMvimentin0.014
NCOR2nuclear receptor corepressor 20.014
PRDX4peroxiredoxin 40.013
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.013
GRB2growth factor receptor-bound protein 20.012
NFE2L1nuclear factor (erythroid-derived 2)-like 10.012
TNFRSF12Atumor necrosis factor receptor superfamily, member 12A0.012
APLP1amyloid beta (A4) precursor-like protein 10.011
APLP2amyloid beta (A4) precursor-like protein 20.011
GAPDHglyceraldehyde-3-phosphate dehydrogenase0.011
CAV1caveolin 1, caveolae protein, 22kDa0.011
FABP4fatty acid binding protein 4, adipocyte0.011
HNF4Ahepatocyte nuclear factor 4, alpha0.010
TUBA1Atubulin, alpha 1a0.010
NTRK1neurotrophic tyrosine kinase, receptor, type 10.010
ORM1orosomucoid 10.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Ndufb10NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 100.030
Cox7ccytochrome c oxidase, subunit VIIc0.029
LOC100363539mitochondrial ribosomal protein L33-like0.027
Mrpl27mitochondrial ribosomal protein L270.023
Arl1ADP-ribosylation factor-like 10.021
Ndufs5NADH dehydrogenase (ubiquinone) Fe-S protein 50.020
Ndufs8NADH dehydrogenase (ubiquinone) Fe-S protein 80.019
Ndufs3NADH dehydrogenase (ubiquinone) Fe-S protein 30.019
LOC301124hypothetical LOC3011240.019
Ndufb6NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 60.018
Timm8btranslocase of inner mitochondrial membrane 8 homolog b (yeast)0.017
Ndufa13NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 130.016
Srp9signal recognition particle 90.015
Ndufs7NADH dehydrogenase (ubiquinone) Fe-S protein 70.015
Uqcr11ubiquinol-cytochrome c reductase, complex III subunit XI0.015
Ict1immature colon carcinoma transcript 10.015
Timm13translocase of inner mitochondrial membrane 13 homolog (yeast)0.015
RGD1306917similar to RIKEN cDNA 2900010M230.015
Robld3roadblock domain containing 30.014
Tceb2transcription elongation factor B (SIII), polypeptide 20.014
Ndufb2NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 20.014
Mrps28mitochondrial ribosomal protein S280.014
Park7Parkinson disease (autosomal recessive, early onset) 70.014
Polr2jpolymerase (RNA) II (DNA directed) polypeptide J0.014
Cox5bcytochrome c oxidase subunit Vb0.014
Ndufa11NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 110.013
Mrps21mitochondrial ribosomal protein S210.013
Atp5hATP synthase, H+ transporting, mitochondrial F0 complex, subunit d0.013
RGD1304704similar to Hypothetical protein CGI-990.013
Mrps16mitochondrial ribosomal protein S160.013
Ndufc1NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 10.013
Atp5lATP synthase, H+ transporting, mitochondrial F0 complex, subunit G0.013
Mrpl20mitochondrial ribosomal protein L200.013
Mrpl13mitochondrial ribosomal protein L130.012
Ntan1N-terminal asparagine amidase0.012
Edf1endothelial differentiation-related factor 10.012
Uqcrfs1ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 10.012
Ndufa2NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 20.012
Mrps33mitochondrial ribosomal protein S330.012
Phpt1phosphohistidine phosphatase 10.012
Fcer1gFc fragment of IgE, high affinity I, receptor for; gamma polypeptide0.012
Ndufa8NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 80.011
Psmc5proteasome (prosome, macropain) 26S subunit, ATPase, 50.011
Ndufb7NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 70.011
Ssbp1single-stranded DNA binding protein 10.011
Atp5oATP synthase, H+ transporting, mitochondrial F1 complex, O subunit0.011
Sdhbsuccinate dehydrogenase complex, subunit B, iron sulfur (Ip)0.011
Chchd3coiled-coil-helix-coiled-coil-helix domain containing 30.011
Ndufa6NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6 (B14)0.011
Ndufb5NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 50.011
Psmb6proteasome (prosome, macropain) subunit, beta type 60.011
Mrpl30mitochondrial ribosomal protein L300.011
Chmp2achromatin modifying protein 2A0.011
Fmc1formation of mitochondrial complexes 1 homolog (S. cerevisiae)0.011
Ly86lymphocyte antigen 860.010
Higd2aHIG1 hypoxia inducible domain family, member 2A0.010
Grpel1GrpE-like 1, mitochondrial0.010
ArhgdibRho, GDP dissociation inhibitor (GDI) beta0.010
Tmed2transmembrane emp24 domain trafficking protein 20.010
Hnrnpa3heterogeneous nuclear ribonucleoprotein A30.010
Pfdn5prefoldin subunit 50.010
Mrpl23mitochondrial ribosomal protein L230.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism