The network for 'chromatin remodeling at centromere' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

chromatin remodeling at centromere

Dynamic structural changes in centromeric DNA.

NameDescriptionProbabilityFunc Analog Organism
Smarcc1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.931
Arid1bAT rich interactive domain 1B (SWI-like)0.789
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.659
Arid1aAT rich interactive domain 1A (SWI-like)0.618
Smarca2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 20.601
Mcm4minichromosome maintenance deficient 4 homolog (S. cerevisiae)0.244
Dckdeoxycytidine kinase0.199
Rad21RAD21 homolog (S. pombe)0.133
Smarcc2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 20.133
Trim59tripartite motif-containing 590.131
Ect2ect2 oncogene0.096
DekDEK oncogene (DNA binding)0.089
Smc2structural maintenance of chromosomes 20.086
Smarcb1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 10.085
C330027C09RikRIKEN cDNA C330027C09 gene0.066
Dnmt3bDNA methyltransferase 3B0.058
Smc4structural maintenance of chromosomes 40.057
Plk4polo-like kinase 4 (Drosophila)0.049
Usp9xubiquitin specific peptidase 9, X chromosome0.045
Cdc7cell division cycle 7 (S. cerevisiae)0.041
Plk1polo-like kinase 1 (Drosophila)0.039
Ckap2cytoskeleton associated protein 20.037
Hdac2histone deacetylase 20.035
Smarce1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 10.034
Chek1checkpoint kinase 1 homolog (S. pombe)0.031
Dna2DNA replication helicase 2 homolog (yeast)0.026
Nek2NIMA (never in mitosis gene a)-related expressed kinase 20.026
Smarcd3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 30.026
Rbl2retinoblastoma-like 20.026
Prmt5protein arginine N-methyltransferase 50.025
Ezh2enhancer of zeste homolog 2 (Drosophila)0.025
Slmapsarcolemma associated protein0.024
Mll5myeloid/lymphoid or mixed-lineage leukemia 50.023
Topbp1topoisomerase (DNA) II binding protein 10.019
Ppp3caprotein phosphatase 3, catalytic subunit, alpha isoform0.019
Ube2tubiquitin-conjugating enzyme E2T (putative)0.018
Rad51ap1RAD51 associated protein 10.018
Cdk1cyclin-dependent kinase 10.018
Wdhd1WD repeat and HMG-box DNA binding protein 10.017
Zfxzinc finger protein X-linked0.017
Rfc3replication factor C (activator 1) 30.017
Prc1protein regulator of cytokinesis 10.017
Haus6HAUS augmin-like complex, subunit 60.017
Racgap1Rac GTPase-activating protein 10.016
Rrm2ribonucleotide reductase M20.016
Ccna2cyclin A20.016
Dtldenticleless homolog (Drosophila)0.016
Cenpkcentromere protein K0.016
E2f5E2F transcription factor 50.016
Nononon-POU-domain-containing, octamer binding protein0.015
Stag2stromal antigen 20.015
Ncapg2non-SMC condensin II complex, subunit G20.015
Bub1budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)0.014
Prim2DNA primase, p58 subunit0.014
Sin3atranscriptional regulator, SIN3A (yeast)0.014
Wlswntless homolog (Drosophila)0.014
Etaa1Ewing's tumor-associated antigen 10.013
Cdc6cell division cycle 6 homolog (S. cerevisiae)0.013
Zfp101zinc finger protein 1010.013
Rad51RAD51 homolog (S. cerevisiae)0.013
Trip13thyroid hormone receptor interactor 130.013
Snrpd1small nuclear ribonucleoprotein D10.013
Kif11kinesin family member 110.013
Cenpc1centromere protein C10.012
Birc5baculoviral IAP repeat-containing 50.012
Actl6aactin-like 6A0.012
Pcm1pericentriolar material 10.012
Tcf12transcription factor 120.012
Cdca8cell division cycle associated 80.011
Hnrnprheterogeneous nuclear ribonucleoprotein R0.011
Eri2exoribonuclease 20.011
Ulk2Unc-51 like kinase 2 (C. elegans)0.011
TtkTtk protein kinase0.011
Arid2AT rich interactive domain 2 (ARID, RFX-like)0.011
Dnmt3aDNA methyltransferase 3A0.011
Txndc16thioredoxin domain containing 160.010
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.010
Hnrnpuheterogeneous nuclear ribonucleoprotein U0.010
Zmynd11zinc finger, MYND domain containing 110.010
Prim1DNA primase, p49 subunit0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
wgwingless0.104
sggshaggy0.056
NNotch0.046
MadMothers against dpp0.044
DlDelta0.039
Ras85DRas oncogene at 85D0.033
brmbrahma0.031
EgfrEpidermal growth factor receptor0.022
spispitz0.019
zipzipper0.016
DDichaete0.014
dppdecapentaplegic0.013
KhcKinesin heavy chain0.011
glglass0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.982
ARID1AAT rich interactive domain 1A (SWI-like)0.887
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.879
ARID1BAT rich interactive domain 1B (SWI1-like)0.716
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 10.481
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 20.437
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 20.412
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 10.335
SMARCB1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 10.205
PBRM1polybromo 10.133
HDAC1histone deacetylase 10.107
CHD4chromodomain helicase DNA binding protein 40.089
SIN3ASIN3 homolog A, transcription regulator (yeast)0.081
HDAC2histone deacetylase 20.062
MTA1metastasis associated 10.060
ZMYND11zinc finger, MYND-type containing 110.059
PARP1poly (ADP-ribose) polymerase 10.045
TRRAPtransformation/transcription domain-associated protein0.033
RBBP4retinoblastoma binding protein 40.032
ARID2AT rich interactive domain 2 (ARID, RFX-like)0.027
MECP2methyl CpG binding protein 2 (Rett syndrome)0.023
PRKDCprotein kinase, DNA-activated, catalytic polypeptide0.023
CARM1coactivator-associated arginine methyltransferase 10.022
NCOR1nuclear receptor corepressor 10.022
WRNWerner syndrome, RecQ helicase-like0.018
BAZ1Bbromodomain adjacent to zinc finger domain, 1B0.017
POLE4polymerase (DNA-directed), epsilon 4 (p12 subunit)0.016
ACTL6Aactin-like 6A0.015
E2F3E2F transcription factor 30.014
CHRAC1chromatin accessibility complex 10.014
WHSC1Wolf-Hirschhorn syndrome candidate 10.013
RCOR1REST corepressor 10.011
RFWD3ring finger and WD repeat domain 30.011
NONOnon-POU domain containing, octamer-binding0.011
FANCAFanconi anemia, complementation group A0.011
DNMT1DNA (cytosine-5-)-methyltransferase 10.011
SMARCD2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 20.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism