The network for 'aerobic respiration' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

aerobic respiration

The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor.

NameDescriptionProbabilityFunc Analog Organism
Cyc1cytochrome c-10.626
Atp5a1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 10.582
Aco2aconitase 2, mitochondrial0.389
Uqcrfs1ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 10.273
Atp5bATP synthase, H+ transporting mitochondrial F1 complex, beta subunit0.144
Cscitrate synthase0.111
Ndufa9NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 90.100
Ndufs1NADH dehydrogenase (ubiquinone) Fe-S protein 10.096
Ndufs2NADH dehydrogenase (ubiquinone) Fe-S protein 20.086
Ndufv1NADH dehydrogenase (ubiquinone) flavoprotein 10.063
Mdh2malate dehydrogenase 2, NAD (mitochondrial)0.054
Idh3gisocitrate dehydrogenase 3 (NAD+), gamma0.053
Uqcrc2ubiquinol cytochrome c reductase core protein 20.039
Uqcrc1ubiquinol-cytochrome c reductase core protein 10.033
Mup10major urinary protein 100.030
LOC100048884novel member of the major urinary protein (Mup) gene family0.030
Suclg1succinate-CoA ligase, GDP-forming, alpha subunit0.029
Mup19major urinary protein 190.021
Ndufb5NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 50.020
Mup9major urinary protein 90.020
Fh1fumarate hydratase 10.018
Idh3aisocitrate dehydrogenase 3 (NAD+) alpha0.016
Mup1major urinary protein 10.015
Dlatdihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)0.012
Mup7major urinary protein 70.012
Sdhdsuccinate dehydrogenase complex, subunit D, integral membrane protein0.012
Ndufs3NADH dehydrogenase (ubiquinone) Fe-S protein 30.011
Mup12major urinary protein 120.011
Sdhasuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.011
Mup2major urinary protein 20.011
Atp5f1ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B10.010
Mup13major urinary protein 130.010
Mup11major urinary protein 110.010
Mup17major urinary protein 170.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
AconAconitase0.032
l(1)G0156lethal (1) G01560.022
blwbellwether0.021
EnoEnolase0.016
ND75NADH:ubiquinone reductase 75kD subunit precursor0.015
CG3731CG3731 gene product from transcript CG3731-RA0.011
CG6439CG6439 gene product from transcript CG6439-RA0.011
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
HDAC1histone deacetylase 10.995
ATP5BATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide0.937
UQCRC2ubiquinol-cytochrome c reductase core protein II0.672
HDAC2histone deacetylase 20.557
IDH3Gisocitrate dehydrogenase 3 (NAD+) gamma0.454
AIFM1apoptosis-inducing factor, mitochondrion-associated, 10.377
SDHAsuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.351
UQCRC1ubiquinol-cytochrome c reductase core protein I0.328
OXA1Loxidase (cytochrome c) assembly 1-like0.263
HADHAhydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit0.228
SLC25A3solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 30.217
PDHXpyruvate dehydrogenase complex, component X0.120
PDHBpyruvate dehydrogenase (lipoamide) beta0.116
SDHBsuccinate dehydrogenase complex, subunit B, iron sulfur (Ip)0.109
HIGD2AHIG1 hypoxia inducible domain family, member 2A0.095
PDHA1pyruvate dehydrogenase (lipoamide) alpha 10.087
NCAPD2non-SMC condensin I complex, subunit D20.068
GOT1glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)0.059
ECH1enoyl CoA hydratase 1, peroxisomal0.058
SUCLG1succinate-CoA ligase, alpha subunit0.053
SIN3ASIN3 homolog A, transcription regulator (yeast)0.050
PRKAR2Aprotein kinase, cAMP-dependent, regulatory, type II, alpha0.046
ACO2aconitase 2, mitochondrial0.044
SNAPINSNAP-associated protein0.041
DLATdihydrolipoamide S-acetyltransferase0.037
HADHBhydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit0.037
MDH2malate dehydrogenase 2, NAD (mitochondrial)0.029
ATP5A1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle0.028
PLDNpallidin homolog (mouse)0.028
NDUFV2NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa0.027
COX5Acytochrome c oxidase subunit Va0.024
USPL1ubiquitin specific peptidase like 10.021
NDUFS2NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)0.018
C3orf15chromosome 3 open reading frame 150.018
HADHhydroxyacyl-CoA dehydrogenase0.018
GPIglucose-6-phosphate isomerase0.018
IDH2isocitrate dehydrogenase 2 (NADP+), mitochondrial0.017
DECR12,4-dienoyl CoA reductase 1, mitochondrial0.017
BLOC1S3biogenesis of lysosomal organelles complex-1, subunit 30.016
FHfumarate hydratase0.016
C21orf33chromosome 21 open reading frame 330.014
GRHPRglyoxylate reductase/hydroxypyruvate reductase0.012
PFDN1prefoldin subunit 10.012
ADRBK1adrenergic, beta, receptor kinase 10.012
ECHS1enoyl CoA hydratase, short chain, 1, mitochondrial0.012
SLC25A11solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 110.012
NDUFB8NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa0.011
PHB2prohibitin 20.010
ACAT1acetyl-CoA acetyltransferase 10.010
VDAC2voltage-dependent anion channel 20.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Atp5a1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle0.997
Mdh1malate dehydrogenase 1, NAD (soluble)0.689
Uqcrfs1ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 10.545
Atp5c1ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 10.538
Slc25a3solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 30.441
Fh1fumarate hydratase 10.437
Mdh2malate dehydrogenase 2, NAD (mitochondrial)0.428
Sdhasuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.293
Sdhdsuccinate dehydrogenase complex, subunit D, integral membrane protein0.240
Idh3Bisocitrate dehydrogenase 3 (NAD+) beta0.226
Cyc1cytochrome c-10.197
Ndufv1NADH dehydrogenase (ubiquinone) flavoprotein 10.134
Ndufs1NADH dehydrogenase (ubiquinone) Fe-S protein 10.119
Atp5g3ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)0.102
Ghitmgrowth hormone inducible transmembrane protein0.100
Vdac2voltage-dependent anion channel 20.063
Atp5f1ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B10.055
Ndufs2NADH dehydrogenase (ubiquinone) Fe-S protein 20.046
Pdhbpyruvate dehydrogenase (lipoamide) beta0.044
Sdhcsuccinate dehydrogenase complex, subunit C, integral membrane protein0.042
Acat1acetyl-coenzyme A acetyltransferase 10.039
Uqcrc2ubiquinol cytochrome c reductase core protein 20.039
Hspd1heat shock protein 1 (chaperonin)0.031
Cycscytochrome c, somatic0.029
Hadhbhydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit0.029
Atp5bATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide0.029
Aco2aconitase 2, mitochondrial0.027
Got1glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)0.027
AuhAU RNA binding protein/enoyl-coenzyme A hydratase0.025
Etfdhelectron-transferring-flavoprotein dehydrogenase0.022
Pdha1pyruvate dehydrogenase (lipoamide) alpha 10.022
Atp6v1e1ATPase, H+ transporting, lysosomal V1 subunit E10.020
Trap1TNF receptor-associated protein 10.018
Slc25a12solute carrier family 25 (mitochondrial carrier, Aralar), member 120.017
Prdx3peroxiredoxin 30.017
Idh3gisocitrate dehydrogenase 3 (NAD), gamma0.016
Slc25a4solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 40.016
Vdac1voltage-dependent anion channel 10.016
Dlatdihydrolipoamide S-acetyltransferase0.014
LOC259246alpha-2u globulin PGCL10.014
Mccc2methylcrotonoyl-Coenzyme A carboxylase 2 (beta)0.012
Ldhblactate dehydrogenase B0.012
Mup5major urinary protein 50.012
Chchd10coiled-coil-helix-coiled-coil-helix domain containing 100.011
Ndufa10l1NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10-like 10.011
Pgk1phosphoglycerate kinase 10.010
Cox7bcytochrome c oxidase subunit VIIb0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
COR1Cor1p0.782
ACB1Acb1p0.735
COX13Cox13p0.723
IDH2Idh2p0.603
COX2Cox2p0.536
CYT1Cyt1p0.534
QCR7Qcr7p0.439
MDH1Mdh1p0.421
PET9Pet9p0.389
COX6Cox6p0.385
PET309Pet309p0.368
SDH2Sdh2p0.342
YFH1Yfh1p0.299
RPM2Rpm2p0.276
QCR6Qcr6p0.267
COBCobp0.244
EMI5Emi5p0.239
SDH1Sdh1p0.236
SDH3Sdh3p0.234
RIP1Rip1p0.224
COX14Cox14p0.202
CYC1Cyc1p0.198
MSS116Mss116p0.191
SCO1Sco1p0.188
QCR10Qcr10p0.187
COX1Cox1p0.176
TIM9Tim9p0.172
PDH1Pdh1p0.169
IFM1Ifm1p0.165
PET100Pet100p0.154
MTO1Mto1p0.149
IDH1Idh1p0.149
LEU2Leu2p0.143
TCM62Tcm62p0.136
COX5ACox5ap0.136
CYB2Cyb2p0.136
PET111Pet111p0.134
COA1Coa1p0.129
NAM2Nam2p0.129
CIR2Cir2p0.129
AAC1Aac1p0.126
HAP4Hap4p0.123
SDH4Sdh4p0.116
MDL2Mdl2p0.114
HUG1Hug1p0.113
ATP6Atp6p0.113
DED1Ded1p0.112
CUP9Cup9p0.111
YMR31Ymr31p0.109
FMP10Fmp10p0.106
OXA1Oxa1p0.106
ACH1Ach1p0.103
ERG10Erg10p0.101
HEM3Hem3p0.099
COX4Cox4p0.099
PET494Pet494p0.096
DIE2Die2p0.094
COX18Cox18p0.093
REG2Reg2p0.093
YLR125Whypothetical protein0.092
COA4Coa4p0.091
YTP1Ytp1p0.090
POR1Por1p0.087
HEM15Hem15p0.086
FAA1Faa1p0.084
ADH5Adh5p0.084
EAP1Eap1p0.083
COX10Cox10p0.083
QCR8Qcr8p0.082
MIC17Mic17p0.081
RPO41Rpo41p0.081
PPM2Ppm2p0.080
HOM2Hom2p0.078
YPR098Chypothetical protein0.075
COX12Cox12p0.075
UBA3Uba3p0.074
FUM1Fum1p0.073
INO1Ino1p0.072
CAF40Caf40p0.070
CLU1Clu1p0.070
AIM31Aim31p0.068
ISU1Isu1p0.067
FMP52Fmp52p0.067
MIC14Mic14p0.067
ODC1Odc1p0.066
RSM28Rsm28p0.066
RGT1Rgt1p0.066
BI4Bi4p0.066
ECL1Ecl1p0.065
PTM1Ptm1p0.063
HTD2Htd2p0.063
OLI1F0-ATP synthase subunit c (ATPase-associated proteolipid), encoded on the mitochondrial genome; mutation confers oligomycin resistance; expression is specifically dependent on the nuclear genes AEP1 and AEP20.062
QCR9Qcr9p0.061
MRS3Mrs3p0.060
COQ9Coq9p0.060
ILV6Ilv6p0.059
CAR1Car1p0.059
YEL073Chypothetical protein0.058
NDE1Nde1p0.058
ICY1Icy1p0.058