The network for 'chemokine secretion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

chemokine secretion

The regulated release of chemokines from a cell.

NameDescriptionProbabilityFunc Analog Organism
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.971
Csf2rb2colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)0.951
Casp4caspase 4, apoptosis-related cysteine peptidase0.365
Il6interleukin 60.333
Il1rl1interleukin 1 receptor-like 10.326
Stat6signal transducer and activator of transcription 60.301
S100a8S100 calcium binding protein A8 (calgranulin A)0.229
Nlrp3NLR family, pyrin domain containing 30.226
Mmp8matrix metallopeptidase 80.175
Il18rapinterleukin 18 receptor accessory protein0.160
Ccl2chemokine (C-C motif) ligand 20.146
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.139
Stat3signal transducer and activator of transcription 30.096
Chi3l3chitinase 3-like 30.081
Cxcr2chemokine (C-X-C motif) receptor 20.077
Il1rninterleukin 1 receptor antagonist0.056
Tlr4toll-like receptor 40.047
S100a9S100 calcium binding protein A9 (calgranulin B)0.042
Il1r2interleukin 1 receptor, type II0.042
Mpeg1macrophage expressed gene 10.041
Slfn4schlafen 40.041
Il18r1interleukin 18 receptor 10.039
Selpselectin, platelet0.035
Chi3l4chitinase 3-like 40.035
Gbp5guanylate binding protein 50.029
Ccr2chemokine (C-C motif) receptor 20.025
Slasrc-like adaptor0.025
Alox5aparachidonate 5-lipoxygenase activating protein0.022
Tgfbitransforming growth factor, beta induced0.021
Aim2absent in melanoma 20.021
Slpisecretory leukocyte peptidase inhibitor0.020
Il33interleukin 330.018
Cd44CD44 antigen0.017
4632428N05RikRIKEN cDNA 4632428N05 gene0.016
Clec4eC-type lectin domain family 4, member e0.016
Ngpneutrophilic granule protein0.015
C1qbcomplement component 1, q subcomponent, beta polypeptide0.015
Tnfrsf9tumor necrosis factor receptor superfamily, member 90.014
Ccr1chemokine (C-C motif) receptor 10.014
RhagRhesus blood group-associated A glycoprotein0.014
Cpa3carboxypeptidase A3, mast cell0.013
Il1binterleukin 1 beta0.013
Laptm5lysosomal-associated protein transmembrane 50.013
Olr1oxidized low density lipoprotein (lectin-like) receptor 10.012
C5ar1complement component 5a receptor 10.012
MefvMediterranean fever0.011
Cxcl2chemokine (C-X-C motif) ligand 20.010
Asprv1aspartic peptidase, retroviral-like 10.010
Myo1gmyosin IG0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.105
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.090
VEGFAvascular endothelial growth factor A0.084
COTL1coactosin-like 1 (Dictyostelium)0.075
EGFRepidermal growth factor receptor0.070
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.064
LATlinker for activation of T cells0.046
CAV1caveolin 1, caveolae protein, 22kDa0.033
SHC2SHC (Src homology 2 domain containing) transforming protein 20.025
SOS1son of sevenless homolog 1 (Drosophila)0.019
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.019
PDGFAplatelet-derived growth factor alpha polypeptide0.016
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.014
APOEapolipoprotein E0.014
IL4interleukin 40.014
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.013
STAT6signal transducer and activator of transcription 6, interleukin-4 induced0.013
PTPRBprotein tyrosine phosphatase, receptor type, B0.013
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.013
CDH5cadherin 5, type 2 (vascular endothelium)0.012
PLCG1phospholipase C, gamma 10.012
TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)0.012
FGFR1fibroblast growth factor receptor 10.011
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.011
PDGFCplatelet derived growth factor C0.011
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.011
NLRC4NLR family, CARD domain containing 40.010
GAB1GRB2-associated binding protein 10.010
NRP1neuropilin 10.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism