The network for 'positive regulation of chemokine secretion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of chemokine secretion

Any process that increases the rate, frequency or extent of chemokine secretion, the regulated release of chemokines from a cell.

NameDescriptionProbabilityFunc Analog Organism
Csf2rb2colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)0.975
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.925
Csf1colony stimulating factor 1 (macrophage)0.915
Casp4caspase 4, apoptosis-related cysteine peptidase0.771
Il1rl1interleukin 1 receptor-like 10.763
Stat6signal transducer and activator of transcription 60.736
Aim2absent in melanoma 20.451
Il1binterleukin 1 beta0.419
Chi3l3chitinase 3-like 30.401
Nlrp3NLR family, pyrin domain containing 30.382
Mmp8matrix metallopeptidase 80.372
S100a9S100 calcium binding protein A9 (calgranulin B)0.289
Gbp5guanylate binding protein 50.263
Il1rapinterleukin 1 receptor accessory protein0.246
Il1r2interleukin 1 receptor, type II0.240
Casp1caspase 10.239
Stat3signal transducer and activator of transcription 30.152
Cxcr2chemokine (C-X-C motif) receptor 20.138
C5ar1complement component 5a receptor 10.128
Il18rapinterleukin 18 receptor accessory protein0.117
Slpisecretory leukocyte peptidase inhibitor0.112
Il6interleukin 60.102
Ccr1chemokine (C-C motif) receptor 10.089
Slfn4schlafen 40.085
Olr1oxidized low density lipoprotein (lectin-like) receptor 10.083
Clec4eC-type lectin domain family 4, member e0.080
Clec4dC-type lectin domain family 4, member d0.077
Cxcl2chemokine (C-X-C motif) ligand 20.074
Chi3l4chitinase 3-like 40.072
Selpselectin, platelet0.069
Ccr2chemokine (C-C motif) receptor 20.069
Adam8a disintegrin and metallopeptidase domain 80.066
Tnfrsf9tumor necrosis factor receptor superfamily, member 90.063
Il1r1interleukin 1 receptor, type I0.063
Il1rninterleukin 1 receptor antagonist0.060
Fpr2formyl peptide receptor 20.057
Il33interleukin 330.057
Tlr4toll-like receptor 40.049
Cd80CD80 antigen0.046
Fgf7fibroblast growth factor 70.042
Slasrc-like adaptor0.040
Ccl6chemokine (C-C motif) ligand 60.039
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.038
Emr1EGF-like module containing, mucin-like, hormone receptor-like sequence 10.037
Il18r1interleukin 18 receptor 10.035
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.035
Ngpneutrophilic granule protein0.033
Ptger2prostaglandin E receptor 2 (subtype EP2)0.032
Lyz2lysozyme 20.031
Msr1macrophage scavenger receptor 10.031
Cd86CD86 antigen0.030
S100a8S100 calcium binding protein A8 (calgranulin A)0.027
Tolliptoll interacting protein0.026
Unc93b1unc-93 homolog B1 (C. elegans)0.024
Cd33CD33 antigen0.023
Klrb1bkiller cell lectin-like receptor subfamily B member 1B0.022
Lair1leukocyte-associated Ig-like receptor 10.022
Csf3rcolony stimulating factor 3 receptor (granulocyte)0.022
Plaurplasminogen activator, urokinase receptor0.022
Mpeg1macrophage expressed gene 10.021
FgrGardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog0.020
Niacr1niacin receptor 10.020
Ear2eosinophil-associated, ribonuclease A family, member 20.020
F10coagulation factor X0.019
Ncf1neutrophil cytosolic factor 10.019
Klra2killer cell lectin-like receptor, subfamily A, member 20.019
Tbxas1thromboxane A synthase 1, platelet0.019
Ppargperoxisome proliferator activated receptor gamma0.018
Spp1secreted phosphoprotein 10.018
Ebi3Epstein-Barr virus induced gene 30.018
1100001G20RikRIKEN cDNA 1100001G20 gene0.018
Cpa3carboxypeptidase A3, mast cell0.018
Cd300lfCD300 antigen like family member F0.018
Lilrb4leukocyte immunoglobulin-like receptor, subfamily B, member 40.017
Cxcl1chemokine (C-X-C motif) ligand 10.017
Traf1TNF receptor-associated factor 10.017
Gdaguanine deaminase0.017
Bst1bone marrow stromal cell antigen 10.016
Pla2g7phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)0.016
Ifitm6interferon induced transmembrane protein 60.015
Cysltr1cysteinyl leukotriene receptor 10.015
Osmroncostatin M receptor0.015
Pilrapaired immunoglobin-like type 2 receptor alpha0.015
Icam5intercellular adhesion molecule 5, telencephalin0.015
Gpr97G protein-coupled receptor 970.015
1600029D21RikRIKEN cDNA 1600029D21 gene0.015
Slc10a6solute carrier family 10 (sodium/bile acid cotransporter family), member 60.015
Mmp12matrix metallopeptidase 120.015
Irg1immunoresponsive gene 10.014
Emr4EGF-like module containing, mucin-like, hormone receptor-like sequence 40.014
Pld4phospholipase D family, member 40.014
Ptgs1prostaglandin-endoperoxide synthase 10.014
Il10rainterleukin 10 receptor, alpha0.014
Il18interleukin 180.014
Tnfrsf18tumor necrosis factor receptor superfamily, member 180.014
Fcgr3Fc receptor, IgG, low affinity III0.014
Hdchistidine decarboxylase0.014
Serpina3nserine (or cysteine) peptidase inhibitor, clade A, member 3N0.014
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.257
CDH5cadherin 5, type 2 (vascular endothelium)0.097
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.088
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.085
APOEapolipoprotein E0.052
PDGFAplatelet-derived growth factor alpha polypeptide0.045
COTL1coactosin-like 1 (Dictyostelium)0.031
VEGFAvascular endothelial growth factor A0.029
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.023
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.021
PDGFCplatelet derived growth factor C0.017
IL4interleukin 40.015
STAT6signal transducer and activator of transcription 6, interleukin-4 induced0.014
LATlinker for activation of T cells0.014
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.013
PTPRBprotein tyrosine phosphatase, receptor type, B0.012
SHC2SHC (Src homology 2 domain containing) transforming protein 20.011
NLRC4NLR family, CARD domain containing 40.011
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism