The network for 'regulation of chemokine secretion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of chemokine secretion

Any process that modulates the rate, frequency or extent of chemokine secretion, the regulated release of chemokines from a cell.

NameDescriptionProbabilityFunc Analog Organism
Csf2rb2colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)0.999
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.999
Csf1colony stimulating factor 1 (macrophage)0.980
Stat3signal transducer and activator of transcription 30.978
Stat6signal transducer and activator of transcription 60.959
Il1rl1interleukin 1 receptor-like 10.951
Nlrp3NLR family, pyrin domain containing 30.859
Il1r1interleukin 1 receptor, type I0.811
Tlr4toll-like receptor 40.589
Il6interleukin 60.586
Il1rapinterleukin 1 receptor accessory protein0.553
Il1r2interleukin 1 receptor, type II0.541
Casp4caspase 4, apoptosis-related cysteine peptidase0.524
Aim2absent in melanoma 20.395
Selpselectin, platelet0.347
Ccr2chemokine (C-C motif) receptor 20.329
Il1binterleukin 1 beta0.309
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.271
Slpisecretory leukocyte peptidase inhibitor0.267
S100a8S100 calcium binding protein A8 (calgranulin A)0.257
Ccl2chemokine (C-C motif) ligand 20.246
Cd44CD44 antigen0.244
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.205
Olr1oxidized low density lipoprotein (lectin-like) receptor 10.200
Il33interleukin 330.200
Slasrc-like adaptor0.188
Tcirg1T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A30.172
Gbp5guanylate binding protein 50.172
Slfn4schlafen 40.171
Il18r1interleukin 18 receptor 10.168
Il1rninterleukin 1 receptor antagonist0.155
Il4rainterleukin 4 receptor, alpha0.146
Myd88myeloid differentiation primary response gene 880.143
Msr1macrophage scavenger receptor 10.133
Cxcl2chemokine (C-X-C motif) ligand 20.131
Clec4eC-type lectin domain family 4, member e0.130
C5ar1complement component 5a receptor 10.124
Ccr1chemokine (C-C motif) receptor 10.116
Osmroncostatin M receptor0.114
Clec4dC-type lectin domain family 4, member d0.104
Tnfrsf9tumor necrosis factor receptor superfamily, member 90.098
Lrg1leucine-rich alpha-2-glycoprotein 10.093
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.092
Adam8a disintegrin and metallopeptidase domain 80.083
Il18rapinterleukin 18 receptor accessory protein0.082
Cd80CD80 antigen0.082
FasFas (TNF receptor superfamily member 6)0.081
Chi3l3chitinase 3-like 30.081
Cxcr2chemokine (C-X-C motif) receptor 20.079
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.078
Serpina3nserine (or cysteine) peptidase inhibitor, clade A, member 3N0.072
Csf3rcolony stimulating factor 3 receptor (granulocyte)0.070
Leprleptin receptor0.068
Mmp8matrix metallopeptidase 80.062
Plaurplasminogen activator, urokinase receptor0.061
Spp1secreted phosphoprotein 10.061
Fpr2formyl peptide receptor 20.058
Cd86CD86 antigen0.055
Bst1bone marrow stromal cell antigen 10.053
Cxcl1chemokine (C-X-C motif) ligand 10.052
Ccl6chemokine (C-C motif) ligand 60.048
Saa3serum amyloid A 30.045
Ptger2prostaglandin E receptor 2 (subtype EP2)0.040
Ptgs1prostaglandin-endoperoxide synthase 10.038
Cpa3carboxypeptidase A3, mast cell0.036
Ldlrlow density lipoprotein receptor0.036
Cd14CD14 antigen0.035
Il4interleukin 40.034
Fpr1formyl peptide receptor 10.033
Tgfb1transforming growth factor, beta 10.033
Il10rainterleukin 10 receptor, alpha0.032
Traf1TNF receptor-associated factor 10.031
Hdchistidine decarboxylase0.030
Ncf1neutrophil cytosolic factor 10.030
Chi3l1chitinase 3-like 10.030
Slc10a6solute carrier family 10 (sodium/bile acid cotransporter family), member 60.029
Ptgs2prostaglandin-endoperoxide synthase 20.029
Lifleukemia inhibitory factor0.029
Klra17killer cell lectin-like receptor, subfamily A, member 170.029
Ghrgrowth hormone receptor0.028
Irf5interferon regulatory factor 50.028
Elk4ELK4, member of ETS oncogene family0.028
Tolliptoll interacting protein0.028
Tbxas1thromboxane A synthase 1, platelet0.028
LOC677008natural killer cell receptor 2B4-like0.027
Ear2eosinophil-associated, ribonuclease A family, member 20.027
Klrb1bkiller cell lectin-like receptor subfamily B member 1B0.026
Il2rainterleukin 2 receptor, alpha chain0.026
Emr1EGF-like module containing, mucin-like, hormone receptor-like sequence 10.026
Il6stinterleukin 6 signal transducer0.025
Dab2disabled homolog 2 (Drosophila)0.025
Ch25hcholesterol 25-hydroxylase0.024
LitafLPS-induced TN factor0.024
Klra9killer cell lectin-like receptor subfamily A, member 90.024
Mmp12matrix metallopeptidase 120.024
Ccl7chemokine (C-C motif) ligand 70.023
Cd300lfCD300 antigen like family member F0.023
Jak2Janus kinase 20.023
1600029D21RikRIKEN cDNA 1600029D21 gene0.023
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.174
NRP1neuropilin 10.125
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.105
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.096
COTL1coactosin-like 1 (Dictyostelium)0.042
PDGFAplatelet-derived growth factor alpha polypeptide0.040
LATlinker for activation of T cells0.034
CAV1caveolin 1, caveolae protein, 22kDa0.034
GAB1GRB2-associated binding protein 10.032
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.030
NLRC4NLR family, CARD domain containing 40.028
SOS1son of sevenless homolog 1 (Drosophila)0.027
PTPRBprotein tyrosine phosphatase, receptor type, B0.026
VEGFAvascular endothelial growth factor A0.022
BCAR1breast cancer anti-estrogen resistance 10.021
APOEapolipoprotein E0.020
PLCG1phospholipase C, gamma 10.020
STAT6signal transducer and activator of transcription 6, interleukin-4 induced0.020
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.018
CDH5cadherin 5, type 2 (vascular endothelium)0.017
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.014
IL4interleukin 40.014
CFHcomplement factor H0.013
SHC2SHC (Src homology 2 domain containing) transforming protein 20.013
TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)0.012
FGFR1fibroblast growth factor receptor 10.012
EGFRepidermal growth factor receptor0.011
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.011
MEFVMediterranean fever0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism