The network for 'urogenital system development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

urogenital system development

The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure.

NameDescriptionProbabilityFunc Analog Organism
Fgfr2fibroblast growth factor receptor 21.000
Wt1Wilms tumor 1 homolog1.000
Bcl2B-cell leukemia/lymphoma 21.000
Ptenphosphatase and tensin homolog1.000
Pax8paired box gene 81.000
Nos3nitric oxide synthase 3, endothelial cell1.000
Pax2paired box gene 21.000
Vegfavascular endothelial growth factor A1.000
Gli3GLI-Kruppel family member GLI31.000
Arandrogen receptor1.000
Pbx1pre B-cell leukemia transcription factor 11.000
Bmp4bone morphogenetic protein 41.000
Tbx3T-box 31.000
Emx2empty spiracles homolog 2 (Drosophila)1.000
Hoxd11homeobox D111.000
Sox2SRY-box containing gene 21.000
Hoxa11homeobox A111.000
Fgfr1fibroblast growth factor receptor 11.000
Lhx1LIM homeobox protein 10.999
Rargretinoic acid receptor, gamma0.999
Pitx2paired-like homeodomain transcription factor 20.999
Shhsonic hedgehog0.999
Itgb1integrin beta 1 (fibronectin receptor beta)0.998
Rarbretinoic acid receptor, beta0.998
Leprleptin receptor0.997
Gdnfglial cell line derived neurotrophic factor0.996
Foxc1forkhead box C10.995
Smad6MAD homolog 6 (Drosophila)0.995
Slc12a1solute carrier family 12, member 10.994
Tcf21transcription factor 210.992
Ren1renin 1 structural0.992
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.992
Foxc2forkhead box C20.991
Hand1heart and neural crest derivatives expressed transcript 10.989
Lama5laminin, alpha 50.989
Pou3f3POU domain, class 3, transcription factor 30.988
Efnb2ephrin B20.987
Retret proto-oncogene0.987
Pkd1polycystic kidney disease 1 homolog0.986
Tbx2T-box 20.985
Col4a3collagen, type IV, alpha 30.985
Hoxa13homeobox A130.983
Pax6paired box gene 60.982
Chd7chromodomain helicase DNA binding protein 70.982
Sox7SRY-box containing gene 70.981
Fgf10fibroblast growth factor 100.977
Hoxa10homeobox A100.976
Jag1jagged 10.976
Gas1growth arrest specific 10.975
Vangl2vang-like 2 (van gogh, Drosophila)0.975
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.974
Kitkit oncogene0.973
Hand2heart and neural crest derivatives expressed transcript 20.973
Smad3MAD homolog 3 (Drosophila)0.973
Dll4delta-like 4 (Drosophila)0.972
Aceangiotensin I converting enzyme (peptidyl-dipeptidase A) 10.971
Vhlvon Hippel-Lindau tumor suppressor0.970
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.969
Lef1lymphoid enhancer binding factor 10.968
Ptpn11protein tyrosine phosphatase, non-receptor type 110.966
Gpc3glypican 30.966
Ptgs2prostaglandin-endoperoxide synthase 20.964
Bicc1bicaudal C homolog 1 (Drosophila)0.964
Gata6GATA binding protein 60.963
Trp63transformation related protein 630.962
Foxg1forkhead box G10.962
Fgf8fibroblast growth factor 80.961
Gdf3growth differentiation factor 30.959
Wnt5awingless-related MMTV integration site 5A0.954
Ror2receptor tyrosine kinase-like orphan receptor 20.953
Twist2twist homolog 2 (Drosophila)0.953
Ghrgrowth hormone receptor0.953
Hoxb6homeobox B60.951
Tlx3T-cell leukemia, homeobox 30.949
Dlx5distal-less homeobox 50.947
Csf1colony stimulating factor 1 (macrophage)0.944
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.944
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.944
Hif1ahypoxia inducible factor 1, alpha subunit0.944
Tgfb1transforming growth factor, beta 10.944
Notch1Notch gene homolog 1 (Drosophila)0.943
Nr5a1nuclear receptor subfamily 5, group A, member 10.937
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.937
Fras1Fraser syndrome 1 homolog (human)0.936
Grem1gremlin 10.932
Foxh1forkhead box H10.931
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.923
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.922
Tgfb2transforming growth factor, beta 20.919
Msx1homeobox, msh-like 10.919
Zic3zinc finger protein of the cerebellum 30.914
Egfrepidermal growth factor receptor0.913
Otx2orthodenticle homolog 2 (Drosophila)0.911
Shesrc homology 2 domain-containing transforming protein E0.910
Gata5GATA binding protein 50.910
Hoxa5homeobox A50.910
Nkx2-1NK2 homeobox 10.909
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
tbx1T-box 10.995
pax2apaired box gene 2a0.982
shhasonic hedgehog a0.965
osr2odd-skipped related 2 (Drosophila)0.920
wt1bwilms tumor 1b0.919
ift88intraflagellar transport 88 homolog0.853
kdrlkinase insert domain receptor like0.832
flhfloating head0.789
kif17kinesin family member 170.747
eya1eyes absent homolog 10.745
ntlano tail a0.728
gdf6agrowth differentiation factor 6a0.726
notch1anotch homolog 1a0.710
rasl11bRAS-like, family 11, member B0.683
emx1empty spiracles homeobox 10.676
emx3empty spiracles homeobox 30.666
rfx2regulatory factor X, 2 (influences HLA class II expression)0.637
nf1aneurofibromin 1a0.577
lhx2bLIM homeobox 2b0.566
lmx1b.1LIM homeobox transcription factor 1, beta 10.566
mibmind bomb0.559
notch3notch homolog 30.541
tbx2bT-box 2b0.530
bmp2abone morphogenetic protein 2a0.526
wt1awilms tumor 1a0.522
lrrc50leucine rich repeat containing 500.506
irx1airoquois homeobox protein 1, a0.501
alcamaactivated leukocyte cell adhesion molecule a0.480
gata3GATA-binding protein 30.465
hoxb5ahomeo box B5a0.464
vegfabvascular endothelial growth factor Ab0.442
wnt8bwingless-type MMTV integration site family, member 8b0.429
lrrc6leucine rich repeat containing 60.426
hnf1baHNF1 homeobox Ba0.425
fn1fibronectin 10.422
dlx3bdistal-less homeobox gene 3b0.413
myod1myogenic differentiation 10.412
bocbrother of CDO0.406
gbx2gastrulation brain homeo box 20.406
lrp2low density lipoprotein-related protein 20.394
lama2laminin, alpha 20.392
tgfb3transforming growth factor, beta 30.377
nkx2.3NK2 transcription factor related 30.373
hnf1bbHNF1 homeobox Bb0.370
hey1hairy/enhancer-of-split related with YRPW motif 10.366
lhx1aLIM homeobox 1a0.364
ism1isthmin 10.356
fgfr4fibroblast growth factor receptor 40.343
oepone-eyed pinhead0.342
wnt5bwingless-type MMTV integration site family, member 5b0.342
klf2aKruppel-like factor 2a0.341
bmp2bbone morphogenetic protein 2b0.339
dusp6dual specificity phosphatase 60.336
nphs1lnephrosis 1, congenital, Finnish type (nephrin)-like0.320
wlswntless homolog (Drosophila)0.317
edn1endothelin 10.314
crb2acrumbs homolog 2a0.306
notch2notch homolog 20.303
jag2jagged 20.302
slc4a4asolute carrier family 4, member 4a0.297
arandrogen receptor0.293
dlx2adistal-less homeobox gene 2a0.291
cxcl12achemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)0.289
ndr2nodal-related 20.288
mecomMDS1 and EVI1 complex locus0.287
wnt11wingless-type MMTV integration site family, member 110.282
igf1rbinsulin-like growth factor 1b receptor0.274
ahi1Abelson helper integration site 10.272
lef1lymphocyte enhancer binding factor 10.270
pcsk5bproprotein convertase subtilisin/kexin type 5b0.266
tp73tumor protein p730.260
wtipWilms tumor 1 interacting protein0.252
atp2a1ATPase, Ca++ transporting, cardiac muscle, fast twitch 10.243
her12hairy-related 120.240
igfbp3insulin-like growth factor binding protein 30.233
tbx2aT-box gene 2a0.232
tbx16T-box gene 160.231
runx2arunt-related transcription factor 2a0.230
hand2heart and neural crest derivatives expressed transcript 20.226
sim1asingle-minded homolog 1a (Drosophila)0.223
metmet proto-oncogene (hepatocyte growth factor receptor)0.222
hoxa13bhomeo box A13b0.220
nkx2.5NK2 transcription factor related 50.218
hey2hairy/enhancer-of-split related with YRPW motif 20.217
foxa2forkhead box A20.215
grhl2agrainyhead-like 2a (Drosophila)0.215
axin2axin 2 (conductin, axil)0.211
six2asine oculis-related homeobox 2a0.210
dnmt8DNA (cytosine-5-)-methyltransferase 80.210
epha4aeph receptor A4a0.206
ift81intraflagellar transport 81 homolog0.202
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.198
bmp4bone morphogenetic protein 40.197
nrp1aneuropilin 1a0.195
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
EgfrEpidermal growth factor receptor0.998
cicubitus interruptus0.987
emcextra macrochaetae0.971
DadDaughters against dpp0.959
l(2)gllethal (2) giant larvae0.948
aopanterior open0.914
slp1sloppy paired 10.900
stumpsCG31317 gene product from transcript CG31317-RC0.846
LanB2Laminin B20.792
rolsrolling pebbles0.761
EcREcdysone receptor0.733
abd-Aabdominal A0.731
mbcmyoblast city0.727
E(spl)Enhancer of split0.709
alpha-Catalpha Catenin0.697
HLHm7E(spl) region transcript m70.676
Pi3K92ECG4141 gene product from transcript CG4141-RB0.596
HLHmgammaE(spl) region transcript mgamma0.547
HLHmbetaE(spl) region transcript mbeta0.526
Cdc42CG12530 gene product from transcript CG12530-RA0.521
LanB1CG7123 gene product from transcript CG7123-RA0.479
Mkp3Mitogen-activated protein kinase phosphatase 30.479
HLHm5E(spl) region transcript m50.449
Stat92ESignal-transducer and activator of transcription protein at 92E0.440
HLHmdeltaE(spl) region transcript mdelta0.418
gcmglial cells missing0.407
Ras85DRas oncogene at 85D0.406
jebjelly belly0.387
AlkCG8250 gene product from transcript CG8250-RA0.345
par-1CG8201 gene product from transcript CG8201-RA0.318
rawCG12437 gene product from transcript CG12437-RB0.272
numbCG3779 gene product from transcript CG3779-RB0.257
PknProtein kinase related to protein kinase N0.254
fz2frizzled 20.245
gbbglass bottom boat0.239
bab2CG9102 gene product from transcript CG9102-RA0.219
eyaeyes absent0.218
argosCG4531 gene product from transcript CG4531-RA0.212
RASSF8CG5053 gene product from transcript CG5053-RA0.205
TomTwin of m40.204
eveeven skipped0.204
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)1.000
RB1retinoblastoma 10.999
SMAD3SMAD family member 30.999
NOTCH1notch 10.999
FHL2four and a half LIM domains 20.995
FGFR2fibroblast growth factor receptor 20.992
VEGFAvascular endothelial growth factor A0.991
JAG1jagged 10.990
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.988
HSP90AB1heat shock protein 90kDa alpha (cytosolic), class B member 10.965
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.955
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.954
MDM2Mdm2 p53 binding protein homolog (mouse)0.947
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.930
NR4A1nuclear receptor subfamily 4, group A, member 10.922
PTPN1protein tyrosine phosphatase, non-receptor type 10.910
NOTCH3notch 30.908
CREBBPCREB binding protein0.903
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.898
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.870
FGF1fibroblast growth factor 1 (acidic)0.864
DYRK1Bdual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B0.861
SMAD2SMAD family member 20.844
RXRAretinoid X receptor, alpha0.842
TIMP3TIMP metallopeptidase inhibitor 30.841
THBS1thrombospondin 10.830
ESR1estrogen receptor 10.821
CUL3cullin 30.819
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.795
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.785
SMAD7SMAD family member 70.779
SMURF2SMAD specific E3 ubiquitin protein ligase 20.752
COL4A3collagen, type IV, alpha 3 (Goodpasture antigen)0.731
CASP3caspase 3, apoptosis-related cysteine peptidase0.730
POU3F2POU class 3 homeobox 20.730
FN1fibronectin 10.686
XIAPX-linked inhibitor of apoptosis0.681
FBLN1fibulin 10.644
SKILSKI-like oncogene0.642
BCL2B-cell CLL/lymphoma 20.633
E2F3E2F transcription factor 30.627
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.621
NCOR2nuclear receptor corepressor 20.597
CCNE1cyclin E10.596
ARandrogen receptor0.594
TSC2tuberous sclerosis 20.586
BMP7bone morphogenetic protein 70.586
PAX3paired box 30.560
FOXF1forkhead box F10.557
IGFBP5insulin-like growth factor binding protein 50.554
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.532
METmet proto-oncogene (hepatocyte growth factor receptor)0.515
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.508
EGR3early growth response 30.497
UHRF2ubiquitin-like with PHD and ring finger domains 20.492
COL2A1collagen, type II, alpha 10.477
SMOsmoothened homolog (Drosophila)0.476
MEIS1Meis homeobox 10.470
TGFB2transforming growth factor, beta 20.459
FGF10fibroblast growth factor 100.452
CTSAcathepsin A0.451
FLNAfilamin A, alpha0.437
TCF4transcription factor 40.434
STC1stanniocalcin 10.433
ITGA3integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)0.423
COL6A1collagen, type VI, alpha 10.412
PTCH1patched 10.403
TAL1T-cell acute lymphocytic leukemia 10.403
CFL1cofilin 1 (non-muscle)0.400
COL4A4collagen, type IV, alpha 40.397
ADRB1adrenergic, beta-1-, receptor0.396
SOX9SRY (sex determining region Y)-box 90.392
GSK3Bglycogen synthase kinase 3 beta0.390
WNK4WNK lysine deficient protein kinase 40.389
KLHL3kelch-like 3 (Drosophila)0.383
NKX2-1NK2 homeobox 10.380
EGR2early growth response 20.376
BADBCL2-associated agonist of cell death0.375
APAF1apoptotic peptidase activating factor 10.373
GATA2GATA binding protein 20.372
PTGISprostaglandin I2 (prostacyclin) synthase0.372
LAPTM5lysosomal protein transmembrane 50.371
HOXA10homeobox A100.370
DVL3dishevelled, dsh homolog 3 (Drosophila)0.370
APBB1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)0.359
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.342
TLE1transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)0.337
HDAC4histone deacetylase 40.325
PLATplasminogen activator, tissue0.321
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.320
COL4A6collagen, type IV, alpha 60.320
MYOD1myogenic differentiation 10.317
JAK1Janus kinase 10.308
BMPR1Abone morphogenetic protein receptor, type IA0.302
TBX2T-box 20.301
TGFB1transforming growth factor, beta 10.296
COL1A1collagen, type I, alpha 10.291
NID1nidogen 10.291
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Bcl2B-cell CLL/lymphoma 20.527
Col1a1collagen, type I, alpha 10.446
Slc5a1solute carrier family 5 (sodium/glucose cotransporter), member 10.400
Pou2f3POU class 2 homeobox 30.384
Nfibnuclear factor I/B0.358
Grin2aglutamate receptor, ionotropic, N-methyl D-aspartate 2A0.352
Psbpc1prostatic steroid binding protein C10.348
Efnb1ephrin B10.341
Flt1FMS-related tyrosine kinase 10.292
Gna15guanine nucleotide binding protein, alpha 150.289
Aebp1AE binding protein 10.284
Itpr2inositol 1,4,5-triphosphate receptor, type 20.275
Cbscystathionine beta synthase0.274
Anxa5annexin A50.267
Ephx1epoxide hydrolase 1, microsomal0.266
Cntfrciliary neurotrophic factor receptor0.262
Lgals7lectin, galactoside-binding, soluble, 70.253
Fgfr2fibroblast growth factor receptor 20.253
Plauplasminogen activator, urokinase0.247
Slit3slit homolog 3 (Drosophila)0.237
Stip1stress-induced phosphoprotein 10.232
Smad7SMAD family member 70.228
Acmsdaminocarboxymuconate semialdehyde decarboxylase0.206
Rararetinoic acid receptor, alpha0.198
Svs1seminal vesicle secretory protein 10.194
Cyp51cytochrome P450, family 510.194
Kcng2potassium voltage-gated channel, subfamily G, member 20.186
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.186
Irs1insulin receptor substrate 10.174
Adrb1adrenergic, beta-1-, receptor0.174
Wnt5awingless-type MMTV integration site family, member 5A0.172
Prrx1paired related homeobox 10.170
GperG protein-coupled estrogen receptor 10.170
Bmp7bone morphogenetic protein 70.168
Timp2TIMP metallopeptidase inhibitor 20.166
Krt5keratin 50.163
Nek9NIMA (never in mitosis gene a)- related kinase 90.161
Lamc1laminin, gamma 10.158
Slc15a1solute carrier family 15 (oligopeptide transporter), member 10.149
Anxa4annexin A40.147
Lamb2laminin, beta 20.145
Fat2FAT tumor suppressor homolog 2 (Drosophila)0.143
Fdft1farnesyl diphosphate farnesyl transferase 10.142
Stat6signal transducer and activator of transcription 60.142
Col3a1collagen, type III, alpha 10.141
Igfbp5insulin-like growth factor binding protein 50.140
MosMoloney sarcoma oncogene0.137
Ccdc80coiled-coil domain containing 800.137
Krt15keratin 150.137
Il13ra1interleukin 13 receptor, alpha 10.136
Hspb2heat shock protein beta 20.133
Cyth3cytohesin 30.133
Ifitm3interferon induced transmembrane protein 30.132
Cd44Cd44 molecule0.131
Htr2b5-hydroxytryptamine (serotonin) receptor 2B0.130
Agtr1aangiotensin II receptor, type 1a0.127
Mrc1mannose receptor, C type 10.125
Sox13SRY (sex determining region Y)-box 130.122
S100a6S100 calcium binding protein A60.121
Ghrgrowth hormone receptor0.119
Atp2a3ATPase, Ca++ transporting, ubiquitous0.118
Fn1fibronectin 10.118
Gpx3glutathione peroxidase 30.116
Itgb1integrin, beta 10.115
Sardhsarcosine dehydrogenase0.115
Pacs1phosphofurin acidic cluster sorting protein 10.114
Fgf16fibroblast growth factor 160.114
Sc4molsterol-C4-methyl oxidase-like0.114
Aif1lallograft inflammatory factor 1-like0.113
Notch2Notch homolog 2 (Drosophila)0.112
Lgals3lectin, galactoside-binding, soluble, 30.111
Sqlesqualene epoxidase0.111
Mpeg1macrophage expressed 10.110
Id1inhibitor of DNA binding 10.110
Pgcprogastricsin (pepsinogen C)0.109
Lhx1LIM homeobox 10.107
Has2hyaluronan synthase 20.106
Ctskcathepsin K0.103
Chrm1cholinergic receptor, muscarinic 10.102
Jak2Janus kinase 20.102
C1rcomplement component 1, r subcomponent0.100
Ube2d4ubiquitin-conjugating enzyme E2D 40.099
Mgpmatrix Gla protein0.099
Sox10SRY (sex determining region Y)-box 100.097
Arandrogen receptor0.096
Gstp1glutathione S-transferase pi 10.096
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.096
Col8a1collagen, type VIII, alpha 10.096
Trhr2thyrotropin releasing hormone receptor 20.096
Aqp2aquaporin 2 (collecting duct)0.095
Gpr182G protein-coupled receptor 1820.095
Ccr1chemokine (C-C motif) receptor 10.091
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism