The network for 'astrocyte fate commitment' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

astrocyte fate commitment

The commitment of a cells to a specific astrocyte fate and its restriction to develop only into an astrocyte.

NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog1.000
Hand1heart and neural crest derivatives expressed transcript 11.000
Pax3paired box gene 31.000
Otx2orthodenticle homolog 2 (Drosophila)1.000
Fgf8fibroblast growth factor 81.000
Gli3GLI-Kruppel family member GLI31.000
Tcfap2atranscription factor AP-2, alpha0.999
Foxc2forkhead box C20.999
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.999
Ascl1achaete-scute complex homolog 1 (Drosophila)0.999
Hand2heart and neural crest derivatives expressed transcript 20.999
Isl1ISL1 transcription factor, LIM/homeodomain0.999
Msx1homeobox, msh-like 10.998
Pax6paired box gene 60.998
Bmp4bone morphogenetic protein 40.997
Prrx1paired related homeobox 10.997
Eya1eyes absent 1 homolog (Drosophila)0.995
Sox11SRY-box containing gene 110.991
Hoxa1homeobox A10.989
Neurod1neurogenic differentiation 10.983
Gli2GLI-Kruppel family member GLI20.976
Pitx2paired-like homeodomain transcription factor 20.976
Prrx2paired related homeobox 20.973
Alx3aristaless-like homeobox 30.971
Igdcc3immunoglobulin superfamily, DCC subclass, member 30.969
Ror2receptor tyrosine kinase-like orphan receptor 20.968
Pax2paired box gene 20.968
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.960
Gbx2gastrulation brain homeobox 20.960
Alx4aristaless-like homeobox 40.957
Tgfb2transforming growth factor, beta 20.951
Onecut1one cut domain, family member 10.951
Foxc1forkhead box C10.950
Sox9SRY-box containing gene 90.943
Dlx5distal-less homeobox 50.940
Meox2mesenchyme homeobox 20.933
Gata4GATA binding protein 40.923
Fgfr2fibroblast growth factor receptor 20.921
Foxd2forkhead box D20.920
Ednraendothelin receptor type A0.916
Foxg1forkhead box G10.904
Ntf3neurotrophin 30.903
Tbx1T-box 10.893
Hoxd13homeobox D130.888
Hoxd3homeobox D30.887
Smosmoothened homolog (Drosophila)0.876
Lhx5LIM homeobox protein 50.869
Sall3sal-like 3 (Drosophila)0.866
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.862
Gpr50G-protein-coupled receptor 500.861
Six3sine oculis-related homeobox 3 homolog (Drosophila)0.860
Nhlh1nescient helix loop helix 10.855
Col2a1collagen, type II, alpha 10.854
Ptf1apancreas specific transcription factor, 1a0.839
Gdnfglial cell line derived neurotrophic factor0.836
Nkx3-2NK3 homeobox 20.835
Hspg2perlecan (heparan sulfate proteoglycan 2)0.825
Nr5a1nuclear receptor subfamily 5, group A, member 10.821
Emx1empty spiracles homolog 1 (Drosophila)0.820
Lhx3LIM homeobox protein 30.816
Sox2SRY-box containing gene 20.797
Col22a1collagen, type XXII, alpha 10.793
Neurog1neurogenin 10.780
Gscgoosecoid homeobox0.774
Efna2ephrin A20.769
Six6sine oculis-related homeobox 6 homolog (Drosophila)0.765
Snai1snail homolog 1 (Drosophila)0.757
Hoxb1homeobox B10.746
Rargretinoic acid receptor, gamma0.741
Neurog2neurogenin 20.740
Fgf3fibroblast growth factor 30.738
Phox2bpaired-like homeobox 2b0.737
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.732
Shesrc homology 2 domain-containing transforming protein E0.732
Lmx1aLIM homeobox transcription factor 1 alpha0.730
Hoxa3homeobox A30.730
Meox1mesenchyme homeobox 10.728
Hoxc5homeobox C50.721
Ebf3early B-cell factor 30.717
Aplnrapelin receptor0.709
Zeb1zinc finger E-box binding homeobox 10.709
Pdx1pancreatic and duodenal homeobox 10.694
Fgfr1fibroblast growth factor receptor 10.690
Hoxd11homeobox D110.684
Gata1GATA binding protein 10.682
Bmp7bone morphogenetic protein 70.682
Pax9paired box gene 90.668
Wnt6wingless-related MMTV integration site 60.660
MecomMDS1 and EVI1 complex locus0.642
Rspo2R-spondin 2 homolog (Xenopus laevis)0.641
UncxUNC homeobox0.628
Neurog3neurogenin 30.621
Atoh7atonal homolog 7 (Drosophila)0.618
Nkx1-2NK1 transcription factor related, locus 2 (Drosophila)0.617
Fgf4fibroblast growth factor 40.610
Pax1paired box gene 10.605
Tcf15transcription factor 150.602
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism