The network for 'blastocyst development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

blastocyst development

The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm.

NameDescriptionProbabilityFunc Analog Organism
Pou5f1POU domain, class 5, transcription factor 10.994
Ctnnb1catenin (cadherin associated protein), beta 10.990
Fgfr2fibroblast growth factor receptor 20.989
Arid1aAT rich interactive domain 1A (SWI-like)0.988
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.987
Bmp4bone morphogenetic protein 40.986
Sox2SRY-box containing gene 20.981
NanogNanog homeobox0.979
Gli3GLI-Kruppel family member GLI30.978
Tcfap2atranscription factor AP-2, alpha0.971
Hand1heart and neural crest derivatives expressed transcript 10.961
Foxc1forkhead box C10.949
Pax3paired box gene 30.948
Shhsonic hedgehog0.946
Eya1eyes absent 1 homolog (Drosophila)0.939
Apcadenomatosis polyposis coli0.931
Smarcc1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.930
Rb1retinoblastoma 10.919
Trp53transformation related protein 530.907
Otx2orthodenticle homolog 2 (Drosophila)0.890
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.889
Sin3atranscriptional regulator, SIN3A (yeast)0.878
Sall4sal-like 4 (Drosophila)0.875
Alx4aristaless-like homeobox 40.851
Tgfbr2transforming growth factor, beta receptor II0.850
CrebbpCREB binding protein0.848
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.844
Ptenphosphatase and tensin homolog0.838
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.829
Fgfr1fibroblast growth factor receptor 10.819
Nodalnodal0.810
Chd7chromodomain helicase DNA binding protein 70.778
Pitx2paired-like homeodomain transcription factor 20.756
Hand2heart and neural crest derivatives expressed transcript 20.753
Fgf8fibroblast growth factor 80.742
Foxh1forkhead box H10.736
Msx2homeobox, msh-like 20.712
Msx1homeobox, msh-like 10.696
Pafah1b1platelet-activating factor acetylhydrolase, isoform 1b, subunit 10.673
FosFBJ osteosarcoma oncogene0.672
Cdx2caudal type homeobox 20.672
Nr5a1nuclear receptor subfamily 5, group A, member 10.667
Alx1ALX homeobox 10.666
Pitx1paired-like homeodomain transcription factor 10.657
Tbx3T-box 30.623
Nr0b1nuclear receptor subfamily 0, group B, member 10.614
Meox2mesenchyme homeobox 20.609
Hoxd13homeobox D130.596
Arid1bAT rich interactive domain 1B (SWI-like)0.596
Dlx5distal-less homeobox 50.595
Sall1sal-like 1 (Drosophila)0.593
Sp1trans-acting transcription factor 10.593
Fgf15fibroblast growth factor 150.586
Smad6MAD homolog 6 (Drosophila)0.566
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.563
Smad4MAD homolog 4 (Drosophila)0.546
Jag1jagged 10.542
Nf1neurofibromatosis 10.535
Lhx1LIM homeobox protein 10.522
Tcfcp2l1transcription factor CP2-like 10.514
Prrx1paired related homeobox 10.509
Pax9paired box gene 90.506
Igdcc3immunoglobulin superfamily, DCC subclass, member 30.499
Bptfbromodomain PHD finger transcription factor0.498
JunJun oncogene0.497
Zic3zinc finger protein of the cerebellum 30.477
Foxg1forkhead box G10.473
Smosmoothened homolog (Drosophila)0.470
Brca1breast cancer 10.468
Tbx15T-box 150.456
Sox3SRY-box containing gene 30.455
Lef1lymphoid enhancer binding factor 10.454
Egr1early growth response 10.449
Smad3MAD homolog 3 (Drosophila)0.433
Hes1hairy and enhancer of split 1 (Drosophila)0.418
Tcfap2ctranscription factor AP-2, gamma0.401
Zeb1zinc finger E-box binding homeobox 10.397
Engendoglin0.384
Gata4GATA binding protein 40.374
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.373
Bmp7bone morphogenetic protein 70.369
Hoxb13homeobox B130.358
Atoh1atonal homolog 1 (Drosophila)0.356
Gbx2gastrulation brain homeobox 20.356
Bmpr1abone morphogenetic protein receptor, type 1A0.346
Cldn6claudin 60.345
Gata6GATA binding protein 60.340
Hdac1histone deacetylase 10.339
Tcf15transcription factor 150.336
Hmx3H6 homeobox 30.336
Pou3f3POU domain, class 3, transcription factor 30.333
Fgf4fibroblast growth factor 40.330
Sox9SRY-box containing gene 90.328
Foxc2forkhead box C20.322
Hesx1homeobox gene expressed in ES cells0.322
Smad7MAD homolog 7 (Drosophila)0.320
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.316
Dll4delta-like 4 (Drosophila)0.315
Cdx1caudal type homeobox 10.313
Foxf1aforkhead box F1a0.312
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
BRCA1breast cancer 1, early onset0.986
PSMC1proteasome (prosome, macropain) 26S subunit, ATPase, 10.981
PSMC5proteasome (prosome, macropain) 26S subunit, ATPase, 50.976
PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.976
PSMB5proteasome (prosome, macropain) subunit, beta type, 50.964
PSMB7proteasome (prosome, macropain) subunit, beta type, 70.961
PSMD1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.957
PSMA6proteasome (prosome, macropain) subunit, alpha type, 60.945
PSMD13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.938
PSMD6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.930
PSMA2proteasome (prosome, macropain) subunit, alpha type, 20.918
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.918
PSMC2proteasome (prosome, macropain) 26S subunit, ATPase, 20.902
MRE11AMRE11 meiotic recombination 11 homolog A (S. cerevisiae)0.881
PSMA1proteasome (prosome, macropain) subunit, alpha type, 10.857
PSMB1proteasome (prosome, macropain) subunit, beta type, 10.850
PSMB3proteasome (prosome, macropain) subunit, beta type, 30.841
MDC1mediator of DNA-damage checkpoint 10.825
PSMC4proteasome (prosome, macropain) 26S subunit, ATPase, 40.821
PSMD11proteasome (prosome, macropain) 26S subunit, non-ATPase, 110.810
H2AFXH2A histone family, member X0.807
PSMA3proteasome (prosome, macropain) subunit, alpha type, 30.801
PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 80.780
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 140.780
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.775
SP1Sp1 transcription factor0.773
POU5F1POU class 5 homeobox 10.765
PSMB2proteasome (prosome, macropain) subunit, beta type, 20.764
EP300E1A binding protein p3000.757
PSMD2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.735
PSMB4proteasome (prosome, macropain) subunit, beta type, 40.725
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 10.713
GABPAGA binding protein transcription factor, alpha subunit 60kDa0.699
SMC2structural maintenance of chromosomes 20.691
PSMD10proteasome (prosome, macropain) 26S subunit, non-ATPase, 100.676
PSMC6proteasome (prosome, macropain) 26S subunit, ATPase, 60.674
PSMA7proteasome (prosome, macropain) subunit, alpha type, 70.673
FANCD2Fanconi anemia, complementation group D20.661
PSMA5proteasome (prosome, macropain) subunit, alpha type, 50.656
PSMD7proteasome (prosome, macropain) 26S subunit, non-ATPase, 70.627
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.614
CDC73cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.591
PSMC3proteasome (prosome, macropain) 26S subunit, ATPase, 30.582
SMAD2SMAD family member 20.555
BARD1BRCA1 associated RING domain 10.555
AATFapoptosis antagonizing transcription factor0.552
FOXD3forkhead box D30.551
RTF1Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.548
LEO1Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.538
PSMA4proteasome (prosome, macropain) subunit, alpha type, 40.491
MSH6mutS homolog 6 (E. coli)0.449
SMAD4SMAD family member 40.436
RAD50RAD50 homolog (S. cerevisiae)0.423
PAFAH1B1platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)0.421
POMPproteasome maturation protein0.387
MKL1megakaryoblastic leukemia (translocation) 10.386
USP14ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)0.362
CTNND1catenin (cadherin-associated protein), delta 10.351
EHFets homologous factor0.342
MAFAv-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)0.327
SMC4structural maintenance of chromosomes 40.323
FOSFBJ murine osteosarcoma viral oncogene homolog0.321
SMAD3SMAD family member 30.320
CAPNS1calpain, small subunit 10.319
PSMB6proteasome (prosome, macropain) subunit, beta type, 60.306
TGFB1transforming growth factor, beta 10.294
WWP2WW domain containing E3 ubiquitin protein ligase 20.280
U2AF1U2 small nuclear RNA auxiliary factor 10.273
HNF4Ahepatocyte nuclear factor 4, alpha0.270
PDX1pancreatic and duodenal homeobox 10.257
FBXO5F-box protein 50.255
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.244
SETD8SET domain containing (lysine methyltransferase) 80.234
CDK4cyclin-dependent kinase 40.231
MYOD1myogenic differentiation 10.225
POLD3polymerase (DNA-directed), delta 3, accessory subunit0.219
JMJD6jumonji domain containing 60.219
PSMD12proteasome (prosome, macropain) 26S subunit, non-ATPase, 120.219
CDC5LCDC5 cell division cycle 5-like (S. pombe)0.213
SNRNP40small nuclear ribonucleoprotein 40kDa (U5)0.212
CCNT1cyclin T10.209
CREBBPCREB binding protein0.200
NCAPH2non-SMC condensin II complex, subunit H20.198
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.197
MYOCDmyocardin0.191
GATA2GATA binding protein 20.190
SOX2SRY (sex determining region Y)-box 20.186
RAD51AP1RAD51 associated protein 10.185
TOPBP1topoisomerase (DNA) II binding protein 10.184
MYOGmyogenin (myogenic factor 4)0.182
MESDC2mesoderm development candidate 20.177
MED6mediator complex subunit 60.172
NCAPD3non-SMC condensin II complex, subunit D30.160
CHEK2CHK2 checkpoint homolog (S. pombe)0.156
MED10mediator complex subunit 100.155
POLA1polymerase (DNA directed), alpha 1, catalytic subunit0.153
MRTO4mRNA turnover 4 homolog (S. cerevisiae)0.150
JUNjun proto-oncogene0.149
RRM1ribonucleotide reductase M10.145
CDC27cell division cycle 27 homolog (S. cerevisiae)0.143
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism