Process View
The network for 'cellular response to bmp stimulus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Gata4 | GATA binding protein 4 | 0.961 | |
Prrx1 | paired related homeobox 1 | 0.931 | |
Col1a1 | collagen, type I, alpha 1 | 0.920 | |
Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.915 | |
Msx1 | homeobox, msh-like 1 | 0.783 | |
Bglap | bone gamma carboxyglutamate protein | 0.637 | |
Otx2 | orthodenticle homolog 2 (Drosophila) | 0.618 | |
Pax3 | paired box gene 3 | 0.552 | |
Col1a2 | collagen, type I, alpha 2 | 0.441 | |
Tgfb2 | transforming growth factor, beta 2 | 0.424 | |
Col5a1 | collagen, type V, alpha 1 | 0.361 | |
Smad1 | MAD homolog 1 (Drosophila) | 0.357 | |
Sox9 | SRY-box containing gene 9 | 0.356 | |
Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.354 | |
Sfrp2 | secreted frizzled-related protein 2 | 0.338 | |
Prrx2 | paired related homeobox 2 | 0.330 | |
Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.300 | |
Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.249 | |
Ntf3 | neurotrophin 3 | 0.238 | |
Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.231 | |
Neurod1 | neurogenic differentiation 1 | 0.223 | |
Axin1 | axin 1 | 0.213 | |
Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.196 | |
Smad4 | MAD homolog 4 (Drosophila) | 0.191 | |
Shh | sonic hedgehog | 0.189 | |
Col3a1 | collagen, type III, alpha 1 | 0.187 | |
Acvr1 | activin A receptor, type 1 | 0.181 | |
Gata1 | GATA binding protein 1 | 0.181 | |
Snai1 | snail homolog 1 (Drosophila) | 0.180 | |
Mecom | MDS1 and EVI1 complex locus | 0.150 | |
Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.147 | |
Runx2 | runt related transcription factor 2 | 0.145 | |
Bglap2 | bone gamma-carboxyglutamate protein 2 | 0.144 | |
Col6a2 | collagen, type VI, alpha 2 | 0.140 | |
Nhlh1 | nescient helix loop helix 1 | 0.133 | |
Fbn1 | fibrillin 1 | 0.111 | |
Smad3 | MAD homolog 3 (Drosophila) | 0.106 | |
Kiss1 | KiSS-1 metastasis-suppressor | 0.105 | |
Ptf1a | pancreas specific transcription factor, 1a | 0.104 | |
Dlx2 | distal-less homeobox 2 | 0.098 | |
Col5a2 | collagen, type V, alpha 2 | 0.097 | |
Fgf8 | fibroblast growth factor 8 | 0.089 | |
Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.087 | |
Tgfbr2 | transforming growth factor, beta receptor II | 0.087 | |
Eln | elastin | 0.085 | |
Col6a1 | collagen, type VI, alpha 1 | 0.078 | |
Twist2 | twist homolog 2 (Drosophila) | 0.078 | |
Foxc2 | forkhead box C2 | 0.075 | |
Bmp7 | bone morphogenetic protein 7 | 0.074 | |
Gli3 | GLI-Kruppel family member GLI3 | 0.067 | |
Gbx2 | gastrulation brain homeobox 2 | 0.066 | |
Gli2 | GLI-Kruppel family member GLI2 | 0.064 | |
Dlx5 | distal-less homeobox 5 | 0.064 | |
Col22a1 | collagen, type XXII, alpha 1 | 0.058 | |
Tal1 | T-cell acute lymphocytic leukemia 1 | 0.058 | |
Col11a1 | collagen, type XI, alpha 1 | 0.057 | |
Obsl1 | obscurin-like 1 | 0.056 | |
Ctsk | cathepsin K | 0.055 | |
Bgn | biglycan | 0.055 | |
Csf1 | colony stimulating factor 1 (macrophage) | 0.055 | |
Hoxb1 | homeobox B1 | 0.055 | |
Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.054 | |
Eng | endoglin | 0.052 | |
Onecut1 | one cut domain, family member 1 | 0.051 | |
Twist1 | twist homolog 1 (Drosophila) | 0.051 | |
Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.049 | |
Dlx1 | distal-less homeobox 1 | 0.048 | |
Neurog2 | neurogenin 2 | 0.048 | |
Erbb2ip | Erbb2 interacting protein | 0.047 | |
Adamts2 | a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2 | 0.046 | |
Cyp19a1 | cytochrome P450, family 19, subfamily a, polypeptide 1 | 0.045 | |
Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.044 | |
Lhcgr | luteinizing hormone/choriogonadotropin receptor | 0.043 | |
Ebf3 | early B-cell factor 3 | 0.042 | |
Fgfr2 | fibroblast growth factor receptor 2 | 0.042 | |
Lep | leptin | 0.041 | |
Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.041 | |
Fstl1 | follistatin-like 1 | 0.040 | |
Efna2 | ephrin A2 | 0.040 | |
Col6a3 | collagen, type VI, alpha 3 | 0.039 | |
Lox | lysyl oxidase | 0.039 | |
Hey1 | hairy/enhancer-of-split related with YRPW motif 1 | 0.038 | |
Smad2 | MAD homolog 2 (Drosophila) | 0.038 | |
Gsc | goosecoid homeobox | 0.036 | |
Gnrhr | gonadotropin releasing hormone receptor | 0.036 | |
Fshr | follicle stimulating hormone receptor | 0.036 | |
Bmpr2 | bone morphogenic protein receptor, type II (serine/threonine kinase) | 0.036 | |
Msx2 | homeobox, msh-like 2 | 0.035 | |
Heyl | hairy/enhancer-of-split related with YRPW motif-like | 0.035 | |
Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.035 | |
Col13a1 | collagen, type XIII, alpha 1 | 0.034 | |
Loxl1 | lysyl oxidase-like 1 | 0.032 | |
Hes5 | hairy and enhancer of split 5 (Drosophila) | 0.032 | |
Fgfr3 | fibroblast growth factor receptor 3 | 0.031 | |
Neurog3 | neurogenin 3 | 0.031 | |
Amh | anti-Mullerian hormone | 0.030 | |
Igdcc3 | immunoglobulin superfamily, DCC subclass, member 3 | 0.030 | |
Hic1 | hypermethylated in cancer 1 | 0.030 | |
Apc | adenomatosis polyposis coli | 0.030 | |
Eya1 | eyes absent 1 homolog (Drosophila) | 0.030 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
BMPR1A | bone morphogenetic protein receptor, type IA | 0.823 | |
SMAD3 | SMAD family member 3 | 0.818 | |
BMP2 | bone morphogenetic protein 2 | 0.717 | |
SMAD7 | SMAD family member 7 | 0.685 | |
FKBP1A | FK506 binding protein 1A, 12kDa | 0.598 | |
SMAD1 | SMAD family member 1 | 0.518 | |
SMAD2 | SMAD family member 2 | 0.448 | |
BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.316 | |
SMAD5 | SMAD family member 5 | 0.236 | |
SMAD4 | SMAD family member 4 | 0.217 | |
SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.170 | |
GDF5 | growth differentiation factor 5 | 0.150 | |
BMPR1B | bone morphogenetic protein receptor, type IB | 0.118 | |
WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 | 0.112 | |
PCYT2 | phosphate cytidylyltransferase 2, ethanolamine | 0.078 | |
FSTL1 | follistatin-like 1 | 0.069 | |
SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.049 | |
ENG | endoglin | 0.046 | |
ACVR1 | activin A receptor, type I | 0.045 | |
PRKG1 | protein kinase, cGMP-dependent, type I | 0.036 | |
SMAD6 | SMAD family member 6 | 0.035 | |
NOG | noggin | 0.034 | |
BMP7 | bone morphogenetic protein 7 | 0.031 | |
SMAD9 | SMAD family member 9 | 0.028 | |
SKIL | SKI-like oncogene | 0.028 | |
TGFB1 | transforming growth factor, beta 1 | 0.024 | |
TGFB3 | transforming growth factor, beta 3 | 0.020 | |
DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.014 | |
PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.013 | |
CXXC5 | CXXC finger protein 5 | 0.013 | |
DCP1A | DCP1 decapping enzyme homolog A (S. cerevisiae) | 0.013 | |
SKI | v-ski sarcoma viral oncogene homolog (avian) | 0.012 | |
BMP4 | bone morphogenetic protein 4 | 0.010 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Lox | lysyl oxidase | 0.062 | |
Drd1a | dopamine receptor D1A | 0.040 | |
Arpp21 | cAMP-regulated phosphoprotein 21 | 0.029 | |
Opcml | opioid binding protein/cell adhesion molecule-like | 0.022 | |
Tpo | thyroid peroxidase | 0.018 | |
Gabrb1 | gamma-aminobutyric acid (GABA) A receptor, beta 1 | 0.015 | |
Camk2a | calcium/calmodulin-dependent protein kinase II alpha | 0.014 | |
Bgn | biglycan | 0.013 | |
Syt6 | synaptotagmin VI | 0.012 | |
Syt10 | synaptotagmin X | 0.010 |