The network for 'production of small rna involved in gene silencing by rna' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

production of small rna involved in gene silencing by rna

The process in which a double-stranded RNA precursor is processed into short (20-30 nt) fragments. RNA cleavage is catalyzed by a Dicer endonuclease.

NameDescriptionProbabilityFunc Analog Organism
Ddx60DEAD (Asp-Glu-Ala-Asp) box polypeptide 600.901
Isg15ISG15 ubiquitin-like modifier0.510
Stat1signal transducer and activator of transcription 10.502
Gbp7guanylate binding protein 70.405
Rtp4receptor transporter protein 40.260
Safbscaffold attachment factor B0.226
Ifit1interferon-induced protein with tetratricopeptide repeats 10.185
Irf9interferon regulatory factor 90.151
Dicer1Dicer1, Dcr-1 homolog (Drosophila)0.140
Oasl22'-5' oligoadenylate synthetase-like 20.140
Usp18ubiquitin specific peptidase 180.117
Samd9lsterile alpha motif domain containing 9-like0.109
Trim25tripartite motif-containing 250.103
Irgm1immunity-related GTPase family M member 10.099
Irf7interferon regulatory factor 70.096
Atrataxia telangiectasia and Rad3 related0.093
Hsf2heat shock factor 20.080
Smad4MAD homolog 4 (Drosophila)0.076
Apcadenomatosis polyposis coli0.075
Parp12poly (ADP-ribose) polymerase family, member 120.062
Ifit3interferon-induced protein with tetratricopeptide repeats 30.060
Irgm2immunity-related GTPase family M member 20.051
Parp14poly (ADP-ribose) polymerase family, member 140.051
Ddx6DEAD (Asp-Glu-Ala-Asp) box polypeptide 60.046
Trim21tripartite motif-containing 210.046
Trim32tripartite motif-containing 320.044
Ddx58DEAD (Asp-Glu-Ala-Asp) box polypeptide 580.040
Lin28alin-28 homolog A (C. elegans)0.039
Stat2signal transducer and activator of transcription 20.039
Ifi44interferon-induced protein 440.033
Ctnnb1catenin (cadherin associated protein), beta 10.031
Droshadrosha, ribonuclease type III0.029
Kitkit oncogene0.029
Lin28blin-28 homolog B (C. elegans)0.028
Parp9poly (ADP-ribose) polymerase family, member 90.027
Cmpk2cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial0.025
Trim30atripartite motif-containing 30A0.025
Bmpr1abone morphogenetic protein receptor, type 1A0.024
Eif2ak2eukaryotic translation initiation factor 2-alpha kinase 20.024
Ptpn11protein tyrosine phosphatase, non-receptor type 110.023
Ifi35interferon-induced protein 350.022
Rsad2radical S-adenosyl methionine domain containing 20.021
Tnrc6ctrinucleotide repeat containing 6C0.020
BC006779cDNA sequence BC0067790.020
Zbp1Z-DNA binding protein 10.018
Sox9SRY-box containing gene 90.017
Ddx39bDEAD (Asp-Glu-Ala-Asp) box polypeptide 39B0.017
Prkdcprotein kinase, DNA activated, catalytic polypeptide0.016
Igtpinterferon gamma induced GTPase0.016
Oas1a2'-5' oligoadenylate synthetase 1A0.016
Parp10poly (ADP-ribose) polymerase family, member 100.014
Amhr2anti-Mullerian hormone type 2 receptor0.014
Dtx3ldeltex 3-like (Drosophila)0.013
Ifit2interferon-induced protein with tetratricopeptide repeats 20.013
Gbp3guanylate binding protein 30.012
Herc6hect domain and RLD 60.012
Esr1estrogen receptor 1 (alpha)0.011
BrafBraf transforming gene0.011
Acin1apoptotic chromatin condensation inducer 10.011
Npc1Niemann Pick type C10.011
Lgals3bplectin, galactoside-binding, soluble, 3 binding protein0.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
rfp-1Protein RFP-10.019
drh-1Protein DRH-10.019
klp-10Protein KLP-100.013
ulp-1Protein ULP-10.012
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
fanclFanconi anemia, complementation group L0.183
vasavasa homolog0.097
nanos3nanos homolog 30.075
hnrnpabheterogeneous nuclear ribonucleoprotein A/B0.032
khdrbs1aKH domain containing, RNA binding, signal transduction associated 1a0.029
hnrnpa0heterogeneous nuclear ribonucleoprotein A00.026
lppr3blipid phosphate phosphatase-related protein type 3b0.025
prmt1protein arginine methyltransferase 10.021
ewsr1bEwing sarcoma breakpoint region 1b0.020
srsf2serine/arginine-rich splicing factor 20.016
brca2breast cancer 2, early onset0.014
ef1aelongation factor 1-alpha0.014
sf1splicing factor 10.014
hnrnpa0lheterogeneous nuclear ribonucleoprotein A0, like0.013
tardbpTAR DNA binding protein0.012
eif2c4eukaryotic translation initiation factor 2C, 40.012
tardbplTAR DNA binding protein, like0.012
senp3aSUMO1/sentrin/SMT3 specific peptidase 3a0.012
rtf1Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.011
prpf8pre-mRNA processing factor 80.011
dnddead end0.011
hnrnpl2heterogeneous nuclear ribonucleoprotein L20.011
sfrs3bsplicing factor, arginine/serine-rich 3b0.010
sfpqsplicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)0.010
khdrbs1bKH domain containing, RNA binding, signal transduction associated 1b0.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
pashapartner of drosha0.975
droshaCG8730 gene product from transcript CG8730-RA0.781
piwiCG6122 gene product from transcript CG6122-RA0.322
zpgzero population growth0.147
spn-Espindle E0.134
CG8443CG8443 gene product from transcript CG8443-RA0.113
Tsc1CG6147 gene product from transcript CG6147-RA0.106
CG10107CG10107 gene product from transcript CG10107-RA0.092
hydhyperplastic discs0.076
bambag of marbles0.059
CTCFCG8591 gene product from transcript CG8591-RA0.059
Su(var)2-10Suppressor of variegation 2-100.044
CHORDCG6198 gene product from transcript CG6198-RA0.041
Patr-1Protein associated with topo II related - 10.039
Su(var)2-HP2CG12864 gene product from transcript CG12864-RB0.038
magomago nashi0.036
BicDBicaudal D0.035
Ge-1CG6181 gene product from transcript CG6181-RA0.035
Ulp1CG12359 gene product from transcript CG12359-RA0.033
ird5immune response deficient 50.033
TER94CG2331 gene product from transcript CG2331-RA0.032
Top2Topoisomerase 20.031
PGRP-LCPeptidoglycan recognition protein LC0.030
Top1Topoisomerase 10.029
MAN1CG3167 gene product from transcript CG3167-RA0.029
Aats-glyGlycyl-tRNA synthetase0.027
Rpd3CG7471 gene product from transcript CG7471-RA0.025
htshu li tai shao0.025
SuURSuppressor of Under-Replication0.024
stilstand still0.021
stetstem cell tumor0.020
Tango6Transport and Golgi organization 60.019
CG5899CG5899 gene product from transcript CG5899-RA0.019
dltdiscs lost0.019
bratbrain tumor0.018
PargPoly(ADP-ribose) glycohydrolase0.018
Sra-1specifically Rac1-associated protein 10.018
Vps16AVacuolar protein sorting 16A0.018
piepineapple eye0.016
RbfRetinoblastoma-family protein0.016
CG5720CG5720 gene product from transcript CG5720-RA0.015
Nup160Nucleoporin 1600.015
JhI-1Juvenile hormone-inducible protein 10.015
orboo18 RNA-binding protein0.013
nudECG8104 gene product from transcript CG8104-RB0.013
Mekk1CG7717 gene product from transcript CG7717-RB0.013
Vps35Vacuolar protein sorting 350.013
CG5871CG5871 gene product from transcript CG5871-RA0.013
msl-3male-specific lethal 30.013
PsaPuromycin sensitive aminopeptidase0.013
LrrkLeucine-rich repeat kinase0.013
Vps25Vacuolar protein sorting 250.012
pgant3polypeptide GalNAc transferase 30.012
SceSex combs extra0.012
Cap-GCG34438 gene product from transcript CG34438-RF0.012
Drp1Dynamin related protein 10.012
CG6686CG6686 gene product from transcript CG6686-RB0.011
DreddDeath related ced-3/Nedd2-like protein0.011
CG2875CG2875 gene product from transcript CG2875-RB0.011
nbsCG6754 gene product from transcript CG6754-RC0.011
l(2)35Bglethal (2) 35Bg0.011
Gcn2CG1609 gene product from transcript CG1609-RA0.011
blotbloated tubules0.011
Gef26CG9491 gene product from transcript CG9491-RB0.010
CG5933CG5933 gene product from transcript CG5933-RA0.010
imdimmune deficiency0.010
fs(1)Ybfemale sterile (1) Yb0.010
CG32185CG32185 gene product from transcript CG32185-RA0.010
Sac1CG9128 gene product from transcript CG9128-RB0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
EIF2C2eukaryotic translation initiation factor 2C, 21.000
EIF2C1eukaryotic translation initiation factor 2C, 11.000
TNRC6Atrinucleotide repeat containing 6A0.994
EIF2AK2eukaryotic translation initiation factor 2-alpha kinase 20.992
DICER1dicer 1, ribonuclease type III0.990
PRKRAprotein kinase, interferon-inducible double stranded RNA dependent activator0.957
EIF2C3eukaryotic translation initiation factor 2C, 30.873
TNRC6Btrinucleotide repeat containing 6B0.846
EIF2C4eukaryotic translation initiation factor 2C, 40.770
TNRC6Ctrinucleotide repeat containing 6C0.713
IPO8importin 80.399
PABPC1poly(A) binding protein, cytoplasmic 10.380
C17orf85chromosome 17 open reading frame 850.242
NCBP1nuclear cap binding protein subunit 1, 80kDa0.143
CYLDcylindromatosis (turban tumor syndrome)0.131
DGCR8DiGeorge syndrome critical region gene 80.109
TRIM25tripartite motif containing 250.101
PAN3PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)0.084
TARBP2TAR (HIV-1) RNA binding protein 20.068
ZC3HAV1zinc finger CCCH-type, antiviral 10.061
DROSHAdrosha, ribonuclease type III0.059
GEMIN4gem (nuclear organelle) associated protein 40.058
FRA10AC1fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 10.045
TRIM71tripartite motif containing 710.035
EIF3Beukaryotic translation initiation factor 3, subunit B0.027
WWP2WW domain containing E3 ubiquitin protein ligase 20.027
MOV10Mov10, Moloney leukemia virus 10, homolog (mouse)0.026
LAP3leucine aminopeptidase 30.025
PARNpoly(A)-specific ribonuclease (deadenylation nuclease)0.021
DTX3Ldeltex 3-like (Drosophila)0.021
PARP12poly (ADP-ribose) polymerase family, member 120.020
RBM8ARNA binding motif protein 8A0.019
TDRD7tudor domain containing 70.018
PARP9poly (ADP-ribose) polymerase family, member 90.015
UPF3BUPF3 regulator of nonsense transcripts homolog B (yeast)0.015
ZFP28zinc finger protein 28 homolog (mouse)0.014
SAMD9sterile alpha motif domain containing 90.013
HERC5hect domain and RLD 50.012
STAT2signal transducer and activator of transcription 2, 113kDa0.011
DDX58DEAD (Asp-Glu-Ala-Asp) box polypeptide 580.011
CHD3chromodomain helicase DNA binding protein 30.010
DHX9DEAH (Asp-Glu-Ala-His) box polypeptide 90.010
DDX23DEAD (Asp-Glu-Ala-Asp) box polypeptide 230.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Glod4glyoxalase domain containing 40.035
Gng10guanine nucleotide binding protein (G protein), gamma 100.021
Brcc3BRCA1/BRCA2-containing complex, subunit 30.019
Pnrc2proline-rich nuclear receptor coactivator 20.014
Sbf1SET binding factor 10.012
Rcn2reticulocalbin 2, EF-hand calcium binding domain0.011
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism