The network for 'positive regulation of chemotaxis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of chemotaxis

Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.

NameDescriptionProbabilityFunc Analog Organism
Ccr2chemokine (C-C motif) receptor 20.938
Csf1colony stimulating factor 1 (macrophage)0.932
Cxcl13chemokine (C-X-C motif) ligand 130.903
Acvr1activin A receptor, type 10.881
Ctnnb1catenin (cadherin associated protein), beta 10.874
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.841
Has1hyaluronan synthase10.829
Ifnginterferon gamma0.823
Selpselectin, platelet0.789
Ltblymphotoxin B0.784
Ccl2chemokine (C-C motif) ligand 20.768
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.768
Tgfbr2transforming growth factor, beta receptor II0.767
Acvrl1activin A receptor, type II-like 10.741
Cd44CD44 antigen0.740
Ccl3chemokine (C-C motif) ligand 30.738
Nrp1neuropilin 10.672
Itgaxintegrin alpha X0.637
Slit3slit homolog 3 (Drosophila)0.624
Ptenphosphatase and tensin homolog0.605
Smad3MAD homolog 3 (Drosophila)0.600
Robo1roundabout homolog 1 (Drosophila)0.599
Ccr1chemokine (C-C motif) receptor 10.550
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.548
Fcgr1Fc receptor, IgG, high affinity I0.537
Mmp9matrix metallopeptidase 90.493
Flt1FMS-like tyrosine kinase 10.491
Cdh5cadherin 50.489
Vegfavascular endothelial growth factor A0.486
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.484
Tnfsf14tumor necrosis factor (ligand) superfamily, member 140.482
Cd40CD40 antigen0.475
Gfra2glial cell line derived neurotrophic factor family receptor alpha 20.463
Map3k14mitogen-activated protein kinase kinase kinase 140.462
Retret proto-oncogene0.457
H2-Aahistocompatibility 2, class II antigen A, alpha0.448
Tnfrsf4tumor necrosis factor receptor superfamily, member 40.444
Kdrkinase insert domain protein receptor0.374
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.370
H2-Eb1histocompatibility 2, class II antigen E beta0.362
Slit2slit homolog 2 (Drosophila)0.350
Gdf1growth differentiation factor 10.348
Kitlkit ligand0.347
C3ar1complement component 3a receptor 10.346
Il6stinterleukin 6 signal transducer0.339
Smad4MAD homolog 4 (Drosophila)0.328
SrcRous sarcoma oncogene0.325
Ccl4chemokine (C-C motif) ligand 40.319
Klrd1killer cell lectin-like receptor, subfamily D, member 10.311
Flt4FMS-like tyrosine kinase 40.309
Bmpr1abone morphogenetic protein receptor, type 1A0.308
Apcadenomatosis polyposis coli0.304
Plxnd1plexin D10.289
Il10interleukin 100.281
Ptgs2prostaglandin-endoperoxide synthase 20.279
Fgf7fibroblast growth factor 70.277
Csf3rcolony stimulating factor 3 receptor (granulocyte)0.273
Ptprbprotein tyrosine phosphatase, receptor type, B0.268
FgrGardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog0.267
Cxcr5chemokine (C-X-C motif) receptor 50.265
Ednrbendothelin receptor type B0.263
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.263
Gab1growth factor receptor bound protein 2-associated protein 10.260
Ctswcathepsin W0.259
P2rx7purinergic receptor P2X, ligand-gated ion channel, 70.257
Ldb3LIM domain binding 30.256
Slfn1schlafen 10.240
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.239
Itgalintegrin alpha L0.237
Fpr1formyl peptide receptor 10.235
Ptk2PTK2 protein tyrosine kinase 20.231
Sirpasignal-regulatory protein alpha0.231
Folr2folate receptor 2 (fetal)0.229
H2-Ab1histocompatibility 2, class II antigen A, beta 10.220
Ccr7chemokine (C-C motif) receptor 70.215
Epas1endothelial PAS domain protein 10.214
Cxcr2chemokine (C-X-C motif) receptor 20.213
Ccl8chemokine (C-C motif) ligand 80.213
Pecam1platelet/endothelial cell adhesion molecule 10.205
Tnftumor necrosis factor0.199
Bdnfbrain derived neurotrophic factor0.197
Tnfsf11tumor necrosis factor (ligand) superfamily, member 110.196
Gzmbgranzyme B0.192
Mmp8matrix metallopeptidase 80.191
Ddr2discoidin domain receptor family, member 20.190
Ifitm6interferon induced transmembrane protein 60.185
Ptgirprostaglandin I receptor (IP)0.182
Klrk1killer cell lectin-like receptor subfamily K, member 10.181
Icam1intercellular adhesion molecule 10.177
Ikzf1IKAROS family zinc finger 10.177
Il6interleukin 60.173
Il1binterleukin 1 beta0.170
Il27rainterleukin 27 receptor, alpha0.169
Lilrb3leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 30.168
Tcf21transcription factor 210.165
Ltalymphotoxin A0.165
Foxp3forkhead box P30.164
Ccr5chemokine (C-C motif) receptor 50.163
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
kdrlkinase insert domain receptor like0.495
nrp1aneuropilin 1a0.375
cdh5cadherin 50.278
cxcl12achemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1)0.164
myod1myogenic differentiation 10.132
slit3slit (Drosophila) homolog 30.093
vegfcvascular endothelial growth factor c0.089
postnperiostin, osteoblast specific factor0.066
sulf1sulfatase 10.063
tie2endothelium-specific receptor tyrosine kinase 20.059
myf5myogenic factor 50.051
tie1endothelium-specific receptor tyrosine kinase 10.049
vegfaavascular endothelial growth factor Aa0.043
mcambmelanoma cell adhesion molecule b0.042
ptgs1prostaglandin-endoperoxide synthase 10.041
spon2aspondin 2a, extracellular matrix protein0.037
nrp2aneuropilin 2a0.036
ltkleukocyte tyrosine kinase0.034
fn1fibronectin 10.033
ergv-ets erythroblastosis virus E26 oncogene like (avian)0.033
sema3dsemaphorin 3d0.031
runx1runt-related transcription factor 10.031
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.029
hlxb9lbhomeo box HB9 like b0.029
prrx1apaired related homeobox 1a0.028
cbfbcore-binding factor, beta subunit0.026
tyrp1btyrosinase-related protein 1b0.026
atoh8atonal homolog 80.025
flt4fms-related tyrosine kinase 40.025
hhiphedgehog interacting protein0.024
efnb2aephrin B2a0.023
slit1aslit homolog 1a (Drosophila)0.023
kdrkinase insert domain receptor (a type III receptor tyrosine kinase)0.022
osr1odd-skipped related 1 (Drosophila)0.022
kcnj1potassium inwardly-rectifying channel, subfamily J, member 10.021
col1a1bcollagen, type I, alpha 1b0.021
spns2spinster homolog 2 (Drosophila)0.021
bnc2basonuclin 20.021
plxnd1plexin D10.020
angptl7angiopoietin-like 70.019
tbx1T-box 10.019
skianuclear oncoprotein skia0.018
slit1bslit homolog 1b (Drosophila)0.018
etv2ets variant gene 20.018
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.017
ccl25bchemokine (C-C motif) ligand 25b0.017
nrp2bneuropilin 2b0.016
grnagranulin a0.015
sdc2syndecan 20.015
hgdhomogentisate 1,2-dioxygenase0.015
ncf1neutrophil cytosolic factor 10.015
metmet proto-oncogene (hepatocyte growth factor receptor)0.014
spon2bspondin 2b, extracellular matrix protein0.014
sfrp2secreted frizzled-related protein 20.014
ptprcprotein tyrosine phosphatase, receptor type, C0.012
rbm22RNA binding motif protein 220.012
rgmbRGM domain family, member B0.012
ptrfbpolymerase I and transcript release factor b0.012
dzip1DAZ interacting protein 10.011
hlxb9lahomeo box HB9 like a0.011
erbb3bv-erb-b2 erythroblastic leukemia viral oncogene homolog 3b0.011
sox7SRY-box containing gene 70.011
ptpn6protein tyrosine phosphatase, non-receptor type 60.011
ext1bexostoses (multiple) 1b0.011
fgf20afibroblast growth factor 20a0.011
dll4delta-like 4 (Drosophila)0.011
cenphcentromere protein H0.010
itga5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
myoglianinCG1838 gene product from transcript CG1838-RD0.037
Trxr-1Thioredoxin reductase-10.026
reporeversed polarity0.018
SmoxSmad on X0.017
l(2)k16918lethal (2) k169180.016
emsempty spiracles0.015
Spn27ASerpin 27A0.014
Fak56DFocal Adhesion Kinase0.014
Hsp23Heat shock protein 230.013
Sra-1specifically Rac1-associated protein 10.013
Pi3K92ECG4141 gene product from transcript CG4141-RB0.012
gogogolden goal0.012
Snap25Synapse protein 250.012
Atf6CG3136 gene product from transcript CG3136-RA0.011
futschCG34387 gene product from transcript CG34387-RC0.011
plexAplexin A0.011
grimCG4345 gene product from transcript CG4345-RA0.011
Cdc42CG12530 gene product from transcript CG12530-RA0.010
CG42256CG42256 gene product from transcript CG42256-RH0.010
CG31999CG31999 gene product from transcript CG31999-RA0.010
TbhTyramine beta hydroxylase0.010
Wnt5Wnt oncogene analog 50.010
CG3563CG3563 gene product from transcript CG3563-RA0.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.998
CCR5chemokine (C-C motif) receptor 50.998
S100BS100 calcium binding protein B0.994
CCL5chemokine (C-C motif) ligand 50.955
VEGFAvascular endothelial growth factor A0.947
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.946
AXLAXL receptor tyrosine kinase0.945
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.932
CXCL9chemokine (C-X-C motif) ligand 90.928
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.924
PTPN1protein tyrosine phosphatase, non-receptor type 10.923
CCL4chemokine (C-C motif) ligand 40.922
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.918
NRP1neuropilin 10.885
PLAUplasminogen activator, urokinase0.882
IL8interleukin 80.850
SNAP23synaptosomal-associated protein, 23kDa0.829
CCR1chemokine (C-C motif) receptor 10.828
DPP4dipeptidyl-peptidase 40.804
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.781
CCR7chemokine (C-C motif) receptor 70.767
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.742
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.720
CCL2chemokine (C-C motif) ligand 20.712
S100A16S100 calcium binding protein A160.701
CCL20chemokine (C-C motif) ligand 200.671
CCL22chemokine (C-C motif) ligand 220.657
CCL8chemokine (C-C motif) ligand 80.642
S100A14S100 calcium binding protein A140.602
CCL19chemokine (C-C motif) ligand 190.589
PDIA3protein disulfide isomerase family A, member 30.586
CTNND1catenin (cadherin-associated protein), delta 10.582
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.578
CXCL5chemokine (C-X-C motif) ligand 50.557
CCL18chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)0.554
CCR2chemokine (C-C motif) receptor 20.536
S100A9S100 calcium binding protein A90.533
IFNGinterferon, gamma0.526
LATlinker for activation of T cells0.519
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)0.516
IL1Binterleukin 1, beta0.508
NAPAN-ethylmaleimide-sensitive factor attachment protein, alpha0.506
MMP9matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)0.499
IL6interleukin 6 (interferon, beta 2)0.459
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.445
CRYABcrystallin, alpha B0.409
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.408
CCL3chemokine (C-C motif) ligand 30.406
NTRK2neurotrophic tyrosine kinase, receptor, type 20.402
CCL13chemokine (C-C motif) ligand 130.387
S100A6S100 calcium binding protein A60.384
CXCL6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.360
IL2RGinterleukin 2 receptor, gamma0.350
S100A1S100 calcium binding protein A10.349
CXCL13chemokine (C-X-C motif) ligand 130.345
CXCL3chemokine (C-X-C motif) ligand 30.332
PRKG1protein kinase, cGMP-dependent, type I0.325
TLR2toll-like receptor 20.323
CDH11cadherin 11, type 2, OB-cadherin (osteoblast)0.318
IL1R2interleukin 1 receptor, type II0.315
ABI2abl-interactor 20.305
CXCL10chemokine (C-X-C motif) ligand 100.289
S100A8S100 calcium binding protein A80.278
EGFRepidermal growth factor receptor0.273
IL2RBinterleukin 2 receptor, beta0.269
PLATplasminogen activator, tissue0.267
IL7Rinterleukin 7 receptor0.252
PLCG1phospholipase C, gamma 10.250
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.248
CCL7chemokine (C-C motif) ligand 70.245
VCAM1vascular cell adhesion molecule 10.245
TLR4toll-like receptor 40.243
GAB1GRB2-associated binding protein 10.241
SNAP25synaptosomal-associated protein, 25kDa0.237
CCR4chemokine (C-C motif) receptor 40.234
COL5A1collagen, type V, alpha 10.234
PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)0.221
CXCL2chemokine (C-X-C motif) ligand 20.211
COL1A2collagen, type I, alpha 20.204
MMP12matrix metallopeptidase 12 (macrophage elastase)0.200
LTAlymphotoxin alpha (TNF superfamily, member 1)0.196
PF4platelet factor 40.196
CD163CD163 molecule0.192
DSG2desmoglein 20.187
CCL11chemokine (C-C motif) ligand 110.180
AQP9aquaporin 90.177
S100PS100 calcium binding protein P0.175
THBS1thrombospondin 10.174
PDGFCplatelet derived growth factor C0.174
TNFtumor necrosis factor0.173
SLAMF8SLAM family member 80.165
GAS6growth arrest-specific 60.162
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.158
EHD1EH-domain containing 10.157
PLAURplasminogen activator, urokinase receptor0.157
PGFplacental growth factor0.151
F3coagulation factor III (thromboplastin, tissue factor)0.151
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Ccl4chemokine (C-C motif) ligand 40.466
Cd14CD14 molecule0.379
Laptm5lysosomal protein transmembrane 50.377
Il8rbinterleukin 8 receptor, beta0.361
Cxcl10chemokine (C-X-C motif) ligand 100.334
Fgfr2fibroblast growth factor receptor 20.331
C5ar1complement component 5a receptor 10.272
Cxcl2chemokine (C-X-C motif) ligand 20.263
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.249
Ccl2chemokine (C-C motif) ligand 20.240
Nek9NIMA (never in mitosis gene a)- related kinase 90.187
Cd83CD83 molecule0.163
Icam1intercellular adhesion molecule 10.150
Il6interleukin 60.148
Pde6hphosphodiesterase 6H, cGMP-specific, cone, gamma0.144
Olr1500olfactory receptor 15000.131
Syngr2synaptogyrin 20.122
Cd53Cd53 molecule0.118
Eef2eukaryotic translation elongation factor 20.117
Cd86CD86 molecule0.113
Pld4phospholipase D family, member 40.110
Ccl7chemokine (C-C motif) ligand 70.105
Ccl3chemokine (C-C motif) ligand 30.105
Bcl2B-cell CLL/lymphoma 20.105
Il1ainterleukin 1 alpha0.100
Jak1Janus kinase 10.098
Slc6a7solute carrier family 6 (neurotransmitter transporter, L-proline), member 70.096
Cd68Cd68 molecule0.093
Adam17ADAM metallopeptidase domain 170.076
Neurl3neuralized homolog 3 (Drosophila)0.076
Dab2disabled homolog 2 (Drosophila)0.074
Mmp10matrix metallopeptidase 100.072
Il1binterleukin 1 beta0.070
Olr1oxidized low density lipoprotein (lectin-like) receptor 10.069
Htr2b5-hydroxytryptamine (serotonin) receptor 2B0.067
Myl7myosin, light chain 7, regulatory0.066
Plauplasminogen activator, urokinase0.065
Dgkgdiacylglycerol kinase, gamma0.062
Smad3SMAD family member 30.060
Hckhemopoietic cell kinase0.059
Mmp12matrix metallopeptidase 120.057
Gnrhrgonadotropin releasing hormone receptor0.056
F2rl2coagulation factor II (thrombin) receptor-like 20.055
Slco2b1solute carrier organic anion transporter family, member 2b10.053
Klrd1killer cell lectin-like receptor, subfamily D, member 10.053
Acap1ArfGAP with coiled-coil, ankyrin repeat and PH domains 10.052
Fcn1ficolin (collagen/fibrinogen domain containing) 10.052
Metmet proto-oncogene0.052
Ptgs2prostaglandin-endoperoxide synthase 20.048
Cd69Cd69 molecule0.048
Serpinh1serine (or cysteine) peptidase inhibitor, clade H, member 10.047
Sycp1synaptonemal complex protein 10.045
Ncr1natural cytotoxicity triggering receptor 10.045
Slc1a1solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 10.045
Seleselectin E0.045
Lypd3Ly6/Plaur domain containing 30.043
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.043
F13a1coagulation factor XIII, A1 polypeptide0.042
Ptk2bPTK2B protein tyrosine kinase 2 beta0.041
Ccdc49coiled-coil domain containing 490.040
LOC690358similar to PR domain containing 110.039
Arandrogen receptor0.039
Ngfnerve growth factor (beta polypeptide)0.039
Pdia4protein disulfide isomerase family A, member 40.038
Cgaglycoprotein hormones, alpha polypeptide0.037
Sirpasignal-regulatory protein alpha0.036
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.036
Map3k8mitogen-activated protein kinase kinase kinase 80.036
Gna12guanine nucleotide binding protein (G protein) alpha 120.036
Fosl1fos-like antigen 10.036
Olfml2bolfactomedin-like 2B0.036
Tgfbr2transforming growth factor, beta receptor II0.035
Il2rginterleukin 2 receptor, gamma0.034
Fibcd1fibrinogen C domain containing 10.034
Col12a1collagen, type XII, alpha 10.033
Hk1hexokinase 10.032
Tgm1transglutaminase 1, K polypeptide0.032
Creb1cAMP responsive element binding protein 10.032
Npr3natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)0.032
Dok2docking protein 20.032
Cxcr4chemokine (C-X-C motif) receptor 40.032
Calcrlcalcitonin receptor-like0.032
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.031
Hist1h1ahistone cluster 1, H1a0.031
Ptafrplatelet-activating factor receptor0.031
Nkg7natural killer cell group 7 sequence0.031
Sec61a1Sec61 alpha 1 subunit (S. cerevisiae)0.031
Ubdubiquitin D0.030
Ccl22chemokine (C-C motif) ligand 220.030
Il2rbinterleukin 2 receptor, beta0.030
Foxi2forkhead box I20.029
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism