The network for 'negative regulation of fat cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of fat cell differentiation

Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation.

NameDescriptionProbabilityFunc Analog Organism
Notch1Notch gene homolog 1 (Drosophila)1.000
Cdkn1bcyclin-dependent kinase inhibitor 1B0.990
Fgfr1fibroblast growth factor receptor 10.989
Dll1delta-like 1 (Drosophila)0.939
Apoeapolipoprotein E0.928
Pax2paired box gene 20.912
Ctnnb1catenin (cadherin associated protein), beta 10.900
Trp53transformation related protein 530.897
Id3inhibitor of DNA binding 30.883
Smad6MAD homolog 6 (Drosophila)0.877
JunJun oncogene0.859
C1qccomplement component 1, q subcomponent, C chain0.782
Gli2GLI-Kruppel family member GLI20.759
Id1inhibitor of DNA binding 10.754
Ptenphosphatase and tensin homolog0.740
Rargretinoic acid receptor, gamma0.738
Gli3GLI-Kruppel family member GLI30.736
Tbx3T-box 30.711
Pax3paired box gene 30.695
Atf4activating transcription factor 40.653
Snai1snail homolog 1 (Drosophila)0.621
Notch2Notch gene homolog 2 (Drosophila)0.615
Wnt3awingless-related MMTV integration site 3A0.606
Rxraretinoid X receptor alpha0.599
Egr1early growth response 10.596
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.582
Ptgs2prostaglandin-endoperoxide synthase 20.580
Ppargperoxisome proliferator activated receptor gamma0.580
Retret proto-oncogene0.576
Hic1hypermethylated in cancer 10.572
Bcl2B-cell leukemia/lymphoma 20.572
FosFBJ osteosarcoma oncogene0.564
Hes1hairy and enhancer of split 1 (Drosophila)0.541
Yap1yes-associated protein 10.526
Twist2twist homolog 2 (Drosophila)0.517
Psen1presenilin 10.510
Dkk1dickkopf homolog 1 (Xenopus laevis)0.488
Smad7MAD homolog 7 (Drosophila)0.484
Nos3nitric oxide synthase 3, endothelial cell0.475
Dlx5distal-less homeobox 50.472
Arandrogen receptor0.471
Wnt1wingless-related MMTV integration site 10.431
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.420
Gdnfglial cell line derived neurotrophic factor0.412
Gpc3glypican 30.411
Sox7SRY-box containing gene 70.409
Jag2jagged 20.404
Chd7chromodomain helicase DNA binding protein 70.403
Ptpn14protein tyrosine phosphatase, non-receptor type 140.393
Axin1axin 10.393
Fbn1fibrillin 10.392
Ahraryl-hydrocarbon receptor0.380
Fgfr2fibroblast growth factor receptor 20.365
Runx1runt related transcription factor 10.362
Tbx2T-box 20.342
Fgf8fibroblast growth factor 80.322
Bmp4bone morphogenetic protein 40.304
Csf2colony stimulating factor 2 (granulocyte-macrophage)0.293
Trp73transformation related protein 730.288
Fzd7frizzled homolog 7 (Drosophila)0.286
Dusp1dual specificity phosphatase 10.285
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.278
Dact1dapper homolog 1, antagonist of beta-catenin (xenopus)0.277
C1qacomplement component 1, q subcomponent, alpha polypeptide0.276
Tead3TEA domain family member 30.272
Foxf1aforkhead box F1a0.271
Arhgef7Rho guanine nucleotide exchange factor (GEF7)0.268
Tcf4transcription factor 40.268
Lrp5low density lipoprotein receptor-related protein 50.262
En1engrailed 10.254
Cyr61cysteine rich protein 610.246
Thrathyroid hormone receptor alpha0.242
Tbrachyury0.235
Rararetinoic acid receptor, alpha0.230
Fosl2fos-like antigen 20.229
Hoxa2homeobox A20.227
Lmx1aLIM homeobox transcription factor 1 alpha0.220
Prrx2paired related homeobox 20.213
Msx1homeobox, msh-like 10.210
Egr2early growth response 20.198
Ror2receptor tyrosine kinase-like orphan receptor 20.198
Ptk2PTK2 protein tyrosine kinase 20.197
Irs2insulin receptor substrate 20.192
Rb1retinoblastoma 10.186
Engendoglin0.186
Tcf7l1transcription factor 7-like 1 (T-cell specific, HMG box)0.184
Hoxa1homeobox A10.184
Gata5GATA binding protein 50.181
Gata6GATA binding protein 60.180
Lef1lymphoid enhancer binding factor 10.177
Tal1T-cell acute lymphocytic leukemia 10.175
Ccl2chemokine (C-C motif) ligand 20.172
Csf1colony stimulating factor 1 (macrophage)0.166
Psen2presenilin 20.165
Efnb1ephrin B10.159
Col1a1collagen, type I, alpha 10.157
Nf1neurofibromatosis 10.157
Wwtr1WW domain containing transcription regulator 10.157
Sim1single-minded homolog 1 (Drosophila)0.156
Nr4a1nuclear receptor subfamily 4, group A, member 10.153
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
TAL1T-cell acute lymphocytic leukemia 10.399
ATF4activating transcription factor 4 (tax-responsive enhancer element B67)0.256
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.199
NOTCH1notch 10.104
CREBBPCREB binding protein0.102
PGRprogesterone receptor0.099
C1QCcomplement component 1, q subcomponent, C chain0.077
NOTCH3notch 30.071
GSK3Bglycogen synthase kinase 3 beta0.066
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.042
C1QAcomplement component 1, q subcomponent, A chain0.040
CEBPGCCAAT/enhancer binding protein (C/EBP), gamma0.036
CLOCKclock homolog (mouse)0.034
ARandrogen receptor0.033
SMAD7SMAD family member 70.030
IRF2BP1interferon regulatory factor 2 binding protein 10.029
FZR1fizzy/cell division cycle 20 related 1 (Drosophila)0.028
SMAD3SMAD family member 30.026
FZD1frizzled homolog 1 (Drosophila)0.026
ATF3activating transcription factor 30.024
FSTL1follistatin-like 10.023
RBPJrecombination signal binding protein for immunoglobulin kappa J region0.020
PPARAperoxisome proliferator-activated receptor alpha0.015
HIC1hypermethylated in cancer 10.014
CDC14BCDC14 cell division cycle 14 homolog B (S. cerevisiae)0.014
PSEN1presenilin 10.014
TBX5T-box 50.013
ZFPM1zinc finger protein, multitype 10.013
FOSFBJ murine osteosarcoma viral oncogene homolog0.013
JUNjun proto-oncogene0.012
EP300E1A binding protein p3000.011
DKK1dickkopf homolog 1 (Xenopus laevis)0.011
THBS1thrombospondin 10.011
WNT3Awingless-type MMTV integration site family, member 3A0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism