The network for 'negative regulation of execution phase of apoptosis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of execution phase of apoptosis

Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis.

NameDescriptionProbabilityFunc Analog Organism
Gopcgolgi associated PDZ and coiled-coil motif containing0.992
DffbDNA fragmentation factor, beta subunit0.965
Wnt5awingless-related MMTV integration site 5A0.938
Fzd1frizzled homolog 1 (Drosophila)0.817
Plin1perilipin 10.752
Plin4perilipin 40.669
Fzd8frizzled homolog 8 (Drosophila)0.653
Gpc3glypican 30.597
Dlg4discs, large homolog 4 (Drosophila)0.558
Gli3GLI-Kruppel family member GLI30.460
Cfdcomplement factor D (adipsin)0.439
Cideccell death-inducing DFFA-like effector c0.404
Smad6MAD homolog 6 (Drosophila)0.327
Fbln1fibulin 10.303
Fzd7frizzled homolog 7 (Drosophila)0.293
Cideacell death-inducing DNA fragmentation factor, alpha subunit-like effector A0.273
Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 10.222
Grb10growth factor receptor bound protein 100.222
Npr3natriuretic peptide receptor 30.209
Dlg2discs, large homolog 2 (Drosophila)0.195
Ptk7PTK7 protein tyrosine kinase 70.190
Nr2f2nuclear receptor subfamily 2, group F, member 20.186
Efnb1ephrin B10.180
Col4a5collagen, type IV, alpha 50.179
Tead2TEA domain family member 20.171
Efna2ephrin A20.167
Gjc1gap junction protein, gamma 10.166
Hes1hairy and enhancer of split 1 (Drosophila)0.160
Mrc2mannose receptor, C type 20.159
Sfrp1secreted frizzled-related protein 10.156
Ror1receptor tyrosine kinase-like orphan receptor 10.155
Vangl2vang-like 2 (van gogh, Drosophila)0.152
Tgfbr3transforming growth factor, beta receptor III0.150
Gas1growth arrest specific 10.149
Dlg1discs, large homolog 1 (Drosophila)0.149
S1pr3sphingosine-1-phosphate receptor 30.139
Prkab1protein kinase, AMP-activated, beta 1 non-catalytic subunit0.136
Smad3MAD homolog 3 (Drosophila)0.129
Efna4ephrin A40.124
Hoxb3homeobox B30.106
Ror2receptor tyrosine kinase-like orphan receptor 20.105
Adipoqadiponectin, C1Q and collagen domain containing0.105
Hoxb6homeobox B60.104
Thrspthyroid hormone responsive SPOT14 homolog (Rattus)0.093
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.092
Sema5asema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A0.091
Hoxd9homeobox D90.087
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.086
Sfrp2secreted frizzled-related protein 20.085
Pparaperoxisome proliferator activated receptor alpha0.084
Cachd1cache domain containing 10.081
Efsembryonal Fyn-associated substrate0.080
Twist1twist homolog 1 (Drosophila)0.079
Fgfr2fibroblast growth factor receptor 20.079
Mfap2microfibrillar-associated protein 20.077
Ptpn14protein tyrosine phosphatase, non-receptor type 140.077
Acvr1activin A receptor, type 10.075
Gpd1glycerol-3-phosphate dehydrogenase 1 (soluble)0.074
Emp2epithelial membrane protein 20.073
Ptgfrprostaglandin F receptor0.072
Clec3bC-type lectin domain family 3, member b0.072
Adrb3adrenergic receptor, beta 30.070
Hic1hypermethylated in cancer 10.070
Vegfavascular endothelial growth factor A0.069
Ucp1uncoupling protein 1 (mitochondrial, proton carrier)0.065
Zfhx4zinc finger homeodomain 40.063
Sox13SRY-box containing gene 130.063
Irs1insulin receptor substrate 10.062
Zfp185zinc finger protein 1850.062
Fabp4fatty acid binding protein 4, adipocyte0.061
Cdoncell adhesion molecule-related/down-regulated by oncogenes0.060
Fzd2frizzled homolog 2 (Drosophila)0.060
Tspan12tetraspanin 120.060
Prrx1paired related homeobox 10.060
Ptch2patched homolog 20.060
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.059
Mafavian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog0.058
Pck1phosphoenolpyruvate carboxykinase 1, cytosolic0.056
Aqp7aquaporin 70.056
Kcna1potassium voltage-gated channel, shaker-related subfamily, member 10.055
Six5sine oculis-related homeobox 5 homolog (Drosophila)0.053
Sox4SRY-box containing gene 40.051
Aplnrapelin receptor0.051
Car3carbonic anhydrase 30.050
Cox8bcytochrome c oxidase, subunit VIIIb0.049
Tbx2T-box 20.049
Prkag1protein kinase, AMP-activated, gamma 1 non-catalytic subunit0.048
Gli2GLI-Kruppel family member GLI20.048
Smoc2SPARC related modular calcium binding 20.048
Bscl2Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)0.046
Ephb3Eph receptor B30.045
Fzd6frizzled homolog 6 (Drosophila)0.044
Sema3csema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C0.043
Fzd4frizzled homolog 4 (Drosophila)0.041
Hoxd8homeobox D80.041
Gdf10growth differentiation factor 100.040
Ddr2discoidin domain receptor family, member 20.040
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
BCL2L1BCL2-like 11.000
BCL2B-cell CLL/lymphoma 20.999
BCL2L11BCL2-like 11 (apoptosis facilitator)0.772
BAK1BCL2-antagonist/killer 10.733
BAXBCL2-associated X protein0.727
MCL1myeloid cell leukemia sequence 1 (BCL2-related)0.712
DFFBDNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)0.246
BADBCL2-associated agonist of cell death0.182
CCL5chemokine (C-C motif) ligand 50.098
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.088
CCR5chemokine (C-C motif) receptor 50.056
CCR2chemokine (C-C motif) receptor 20.050
BIDBH3 interacting domain death agonist0.044
PMAIP1phorbol-12-myristate-13-acetate-induced protein 10.035
IFNGinterferon, gamma0.034
TP53BP2tumor protein p53 binding protein, 20.029
IL2RBinterleukin 2 receptor, beta0.027
CCR4chemokine (C-C motif) receptor 40.025
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.020
RNF144Bring finger protein 144B0.020
BIKBCL2-interacting killer (apoptosis-inducing)0.014
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.014
AMBRA1autophagy/beclin-1 regulator 10.012
CXCR6chemokine (C-X-C motif) receptor 60.012
CD40LGCD40 ligand0.012
CXCR3chemokine (C-X-C motif) receptor 30.011
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism