The network for 'positive regulation of mitochondrial fission' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of mitochondrial fission

Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.

NameDescriptionProbabilityFunc Analog Organism
Lrrk2leucine-rich repeat kinase 20.165
Mfn2mitofusin 20.129
Ptp4a1protein tyrosine phosphatase 4a10.065
Kpna3karyopherin (importin) alpha 30.026
Ube2d3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.026
Mlycdmalonyl-CoA decarboxylase0.023
Cycscytochrome c, somatic0.023
Gm9880predicted gene 98800.019
TctaT-cell leukemia translocation altered gene0.019
Ube2g1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans)0.017
Hccsholocytochrome c synthetase0.017
Uba3ubiquitin-like modifier activating enzyme 30.014
Slc30a9solute carrier family 30 (zinc transporter), member 90.014
Pparaperoxisome proliferator activated receptor alpha0.014
Ugp2UDP-glucose pyrophosphorylase 20.012
Pgk1phosphoglycerate kinase 10.012
Timm8a1translocase of inner mitochondrial membrane 8 homolog a1 (yeast)0.012
Wdr45WD repeat domain 450.010
Ndrg2N-myc downstream regulated gene 20.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
NNotch0.136
phlpole hole0.027
DlDelta0.023
wgwingless0.022
Ras85DRas oncogene at 85D0.014
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
BNIP3BCL2/adenovirus E1B 19kDa interacting protein 30.986
BNIP3LBCL2/adenovirus E1B 19kDa interacting protein 3-like0.971
DNM1Ldynamin 1-like0.934
MAP1LC3Bmicrotubule-associated protein 1 light chain 3 beta0.869
ZNF746zinc finger protein 7460.279
MFN2mitofusin 20.167
FIS1fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)0.141
BCAP31B-cell receptor-associated protein 310.118
UBASH3Bubiquitin associated and SH3 domain containing B0.114
SQSTM1sequestosome 10.081
TMEM11transmembrane protein 110.078
NBR1neighbor of BRCA1 gene 10.067
MKRN1makorin ring finger protein 10.061
BCL2B-cell CLL/lymphoma 20.059
SMCR7LSmith-Magenis syndrome chromosome region, candidate 7-like0.054
ZNHIT1zinc finger, HIT-type containing 10.054
GNB5guanine nucleotide binding protein (G protein), beta 50.047
OPA1optic atrophy 1 (autosomal dominant)0.040
DCTN3dynactin 3 (p22)0.033
VPS28vacuolar protein sorting 28 homolog (S. cerevisiae)0.030
MAP1LC3Amicrotubule-associated protein 1 light chain 3 alpha0.029
YPEL5yippee-like 5 (Drosophila)0.022
C19orf56chromosome 19 open reading frame 560.021
ZFAND5zinc finger, AN1-type domain 50.018
ROBO2roundabout, axon guidance receptor, homolog 2 (Drosophila)0.017
GBASglioblastoma amplified sequence0.016
RABAC1Rab acceptor 1 (prenylated)0.015
ZRANB1zinc finger, RAN-binding domain containing 10.014
PDCD2programmed cell death 20.014
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.013
HAGHhydroxyacylglutathione hydrolase0.011
MXI1MAX interactor 10.011
POLR2Jpolymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa0.011
KLF5Kruppel-like factor 5 (intestinal)0.011
MARCH5membrane-associated ring finger (C3HC4) 50.010
GABARAPGABA(A) receptor-associated protein0.010
SPAG9sperm associated antigen 90.010
EDF1endothelial differentiation-related factor 10.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism