The network for 'negative regulation of mrna processing' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of mrna processing

Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA processing.

NameDescriptionProbabilityFunc Analog Organism
Hnrpdlheterogeneous nuclear ribonucleoprotein D-like0.807
Trim28tripartite motif-containing 280.773
Hnrnpa3heterogeneous nuclear ribonucleoprotein A30.523
Pabpn1poly(A) binding protein, nuclear 10.444
Sfpqsplicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)0.437
Ddx39bDEAD (Asp-Glu-Ala-Asp) box polypeptide 39B0.421
Srrtserrate RNA effector molecule homolog (Arabidopsis)0.379
Fusfusion, derived from t(12;16) malignant liposarcoma (human)0.358
Srsf2serine/arginine-rich splicing factor 20.280
Srsf3serine/arginine-rich splicing factor 30.277
Hnrnph1heterogeneous nuclear ribonucleoprotein H10.276
Hnrnpa1heterogeneous nuclear ribonucleoprotein A10.241
Srsf6serine/arginine-rich splicing factor 60.223
Hnrnpdheterogeneous nuclear ribonucleoprotein D0.222
Hmgn1high mobility group nucleosomal binding domain 10.207
Ewsr1Ewing sarcoma breakpoint region 10.172
TardbpTAR DNA binding protein0.151
Srsf7serine/arginine-rich splicing factor 70.146
Srsf1serine/arginine-rich splicing factor 10.141
Ddx5DEAD (Asp-Glu-Ala-Asp) box polypeptide 50.121
Hnrnpkheterogeneous nuclear ribonucleoprotein K0.106
Tra2btransformer 2 beta homolog (Drosophila)0.098
Ptmaprothymosin alpha0.097
Ctbp1C-terminal binding protein 10.082
Ppm1gprotein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform0.073
Raver2ribonucleoprotein, PTB-binding 20.072
Tra2atransformer 2 alpha homolog (Drosophila)0.067
Hnrnpa2b1heterogeneous nuclear ribonucleoprotein A2/B10.066
Safbscaffold attachment factor B0.064
Akr1c13aldo-keto reductase family 1, member C130.061
Hmgb1high mobility group box 10.060
Akr1c12aldo-keto reductase family 1, member C120.056
Hnrnpmheterogeneous nuclear ribonucleoprotein M0.051
Pcbp1poly(rC) binding protein 10.051
Rnps1ribonucleic acid binding protein S10.049
Srsf11serine/arginine-rich splicing factor 110.049
Khdrbs1KH domain containing, RNA binding, signal transduction associated 10.049
SetSET nuclear oncogene0.045
Ptges3prostaglandin E synthase 3 (cytosolic)0.044
Srsf9serine/arginine-rich splicing factor 90.044
Rbm14RNA binding motif protein 140.038
Sf3a2splicing factor 3a, subunit 20.037
Akap8A kinase (PRKA) anchor protein 80.036
Fubp1far upstream element (FUSE) binding protein 10.036
Mat2amethionine adenosyltransferase II, alpha0.032
Hnrnpa0heterogeneous nuclear ribonucleoprotein A00.030
Sumo2SMT3 suppressor of mif two 3 homolog 2 (yeast)0.030
Luc7l3LUC7-like 3 (S. cerevisiae)0.029
Usp10ubiquitin specific peptidase 100.028
Safb2scaffold attachment factor B20.027
Hdgfhepatoma-derived growth factor0.025
Raver1ribonucleoprotein, PTB-binding 10.025
Taf1dTATA box binding protein (Tbp)-associated factor, RNA polymerase I, D0.024
2310036O22RikRIKEN cDNA 2310036O22 gene0.023
Srek1splicing regulatory glutamine/lysine-rich protein 10.022
Pom121nuclear pore membrane protein 1210.021
Srsf4serine/arginine-rich splicing factor 40.021
Cdk2ap1CDK2 (cyclin-dependent kinase 2)-associated protein 10.019
Hcfc1host cell factor C10.019
Snrpasmall nuclear ribonucleoprotein polypeptide A0.019
Senp3SUMO/sentrin specific peptidase 30.019
H3f3bH3 histone, family 3B0.018
Usp7ubiquitin specific peptidase 70.018
Brd4bromodomain containing 40.018
Lbrlamin B receptor0.018
Matr3matrin 30.018
Rbm10RNA binding motif protein 100.017
Tfdp1transcription factor Dp 10.017
Cbx3chromobox homolog 3 (Drosophila HP1 gamma)0.017
Upf1UPF1 regulator of nonsense transcripts homolog (yeast)0.017
Pprc1peroxisome proliferative activated receptor, gamma, coactivator-related 10.017
CtcfCCCTC-binding factor0.016
Nononon-POU-domain-containing, octamer binding protein0.016
Enoph1enolase-phosphatase 10.016
Pa2g4proliferation-associated 2G40.016
Puf60poly-U binding splicing factor 600.016
Larp1La ribonucleoprotein domain family, member 10.016
Prpf38bPRP38 pre-mRNA processing factor 38 (yeast) domain containing B0.016
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.015
H2afyH2A histone family, member Y0.015
G3bp1Ras-GTPase-activating protein SH3-domain binding protein 10.015
Ubtfupstream binding transcription factor, RNA polymerase I0.015
Kdm2blysine (K)-specific demethylase 2B0.015
Cpsf6cleavage and polyadenylation specific factor 60.014
Rbbp7retinoblastoma binding protein 70.014
Lamp3lysosomal-associated membrane protein 30.014
Syncripsynaptotagmin binding, cytoplasmic RNA interacting protein0.014
U2af2U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 20.014
Carm1coactivator-associated arginine methyltransferase 10.013
Tdgthymine DNA glycosylase0.013
Hnrnph2heterogeneous nuclear ribonucleoprotein H20.013
Rbm8aRNA binding motif protein 8a0.013
Qrich1glutamine-rich 10.013
RbmxrtRNA binding motif protein, X chromosome retrogene0.013
Thrap3thyroid hormone receptor associated protein 30.012
Parp2poly (ADP-ribose) polymerase family, member 20.012
Srsf10serine/arginine-rich splicing factor 100.012
2500003M10RikRIKEN cDNA 2500003M10 gene0.012
Ncoa5nuclear receptor coactivator 50.012
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
cx43.4connexin 43.40.232
tgif1TGFB-induced factor homeobox 10.112
ssbSjogren syndrome antigen B (autoantigen La)0.107
khdrbs1aKH domain containing, RNA binding, signal transduction associated 1a0.104
h2afvlH2A histone family, member V, like0.096
sf1splicing factor 10.083
yap1Yes-associated protein 10.074
nhp2NHP2 ribonucleoprotein homolog (yeast)0.071
sf3b4splicing factor 3b, subunit 40.067
hnrnpa0heterogeneous nuclear ribonucleoprotein A00.067
mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.066
jupjunction plakoglobin0.062
psma8proteasome (prosome, macropain) subunit, alpha type, 80.054
snrnp70small nuclear ribonucleoprotein 70 (U1)0.048
snrpd3lsmall nuclear ribonucleoprotein D3 polypeptide, like0.047
sumo3aSMT3 suppressor of mif two 3 homolog 3a0.045
cherpcalcium homeostasis endoplasmic reticulum protein0.039
sf3a2splicing factor 3a, subunit 20.036
hmga1ahigh mobility group AT-hook 1a0.036
anp32bacidic (leucine-rich) nuclear phosphoprotein 32 family, member B0.035
krt8keratin 80.033
tia1lcytotoxic granule-associated RNA binding protein 1, like0.032
LOC560606novel protein similar to human and mouse leishmanolysin-like (metallopeptidase M8 family) (LMLN)0.032
khsrpKH-type splicing regulatory protein0.031
matr3lmatrin 3-like0.031
cpsf6cleavage and polyadenylation specific factor 60.029
ddx39bDEAD (Asp-Glu-Ala-Asp) box polypeptide 39b0.029
pcdh2acprotocadherin 2 alpha c0.027
ctnnacatenin (cadherin-associated protein), alpha0.026
rqcd1RCD1 required for cell differentiation1 homolog (S. pombe)0.025
slc30a6solute carrier family 30 (zinc transporter), member 60.023
srsf11serine/arginine-rich splicing factor 110.023
lrmplymphoid-restricted membrane protein0.022
setbSET translocation (myeloid leukemia-associated) B0.022
marcksamyristoylated alanine rich protein kinase C substrate a0.021
LOC100331639hypothetical protein LOC1003316390.021
gng5guanine nucleotide binding protein (G protein), gamma 50.021
nucks1anuclear casein kinase and cyclin-dependent kinase substrate 1a0.021
celsr1acadherin EGF LAG seven-pass G-type receptor 1a0.021
snrpcsmall nuclear ribonucleoprotein polypeptide C0.020
actn4actinin, alpha 40.020
caprin1acell cycle associated protein 1a0.020
prpf39PRP39 pre-mRNA processing factor 39 homolog (yeast)0.020
ftsjFtsJ homolog 3 (E. coli)0.019
hnrnpabheterogeneous nuclear ribonucleoprotein A/B0.019
hn1lhematological and neurological expressed 1-like0.019
ctnnb1catenin (cadherin-associated protein), beta 10.019
ctsccathepsin C0.019
ddx39aaDEAD (Asp-Glu-Ala-Asp) box polypeptide 39Aa0.018
srrm1serine/arginine repetitive matrix 10.018
nr2f6anuclear receptor subfamily 2, group F, member 6a0.018
hnrplheterogeneous nuclear ribonucleoprotein L0.018
kdm1alysine (K)-specific demethylase 1a0.018
rfc2replication factor C (activator 1) 20.017
tram1translocating chain-associating membrane protein 10.017
LOC100004809protein FAM78B-like0.017
syncriplsynaptotagmin binding, cytoplasmic RNA interacting protein, like0.017
nrxn1aneurexin 1a0.017
dbtdihydrolipoamide branched chain transacylase E20.017
ranras-related nuclear protein0.017
adkaadenosine kinase a0.017
fb06f03high-mobility group nucleosome binding domain 1-like0.017
nup50nucleoporin 500.017
smu1smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)0.017
ube2l3aubiquitin-conjugating enzyme E2L 3a0.016
npm4nucleophosmin/nucleoplasmin, 40.016
slc30a4solute carrier family 30 (zinc transporter), member 40.016
epha2eph receptor A20.016
pa2g4aproliferation-associated 2G4, a0.016
u2af1U2(RNU2) small nuclear RNA auxiliary factor 10.016
lsm14abLSM14 homolog Ab (SCD6, S. cerevisiae)0.016
srsf2serine/arginine-rich splicing factor 20.015
gatad2aGATA zinc finger domain containing 2A0.015
ef1ETS-related factor10.015
eftud2elongation factor Tu GTP binding domain containing 20.015
sav1salvador homolog 1 (Drosophila)0.015
zff9zinc finger protein 90.015
srsf1aserine/arginine-rich splicing factor 1a0.015
thoc4THO complex 40.015
grwd1glutamate-rich WD repeat containing 10.014
rbm39aRNA binding motif protein 39a0.014
nrxn3aneurexin 3a0.014
usp10ubiquitin specific peptidase 100.014
slc43a1asolute carrier family 43, member 1a0.014
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Ras85DRas oncogene at 85D0.053
phlpole hole0.033
RecQ4CG7487 gene product from transcript CG7487-RA0.031
Pi3K92ECG4141 gene product from transcript CG4141-RB0.025
EgfrEpidermal growth factor receptor0.021
EcREcdysone receptor0.015
ftz-f1ftz transcription factor 10.013
tefutelomere fusion0.013
RpL19Ribosomal protein L190.012
CG10219CG10219 gene product from transcript CG10219-RA0.012
RpS23Ribosomal protein S230.012
RpS17Ribosomal protein S170.012
RpLP0Ribosomal protein LP00.010
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
TRA2Btransformer 2 beta homolog (Drosophila)0.829
RNPS1RNA binding protein S1, serine-rich domain0.777
SRSF1serine/arginine-rich splicing factor 10.723
SRSF6serine/arginine-rich splicing factor 60.673
SRSF2serine/arginine-rich splicing factor 20.654
SRRM1serine/arginine repetitive matrix 10.619
SRSF3serine/arginine-rich splicing factor 30.580
SRPK2SRSF protein kinase 20.531
HNRNPUheterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)0.525
U2AF1U2 small nuclear RNA auxiliary factor 10.500
U2AF2U2 small nuclear RNA auxiliary factor 20.496
HNRNPRheterogeneous nuclear ribonucleoprotein R0.473
HNRNPH1heterogeneous nuclear ribonucleoprotein H1 (H)0.422
PCBP1poly(rC) binding protein 10.413
HNRNPA1heterogeneous nuclear ribonucleoprotein A10.380
SF3A2splicing factor 3a, subunit 2, 66kDa0.222
PNNpinin, desmosome associated protein0.180
SRSF7serine/arginine-rich splicing factor 70.164
DDX3XDEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked0.149
HNRNPH3heterogeneous nuclear ribonucleoprotein H3 (2H9)0.126
SRPK1SRSF protein kinase 10.123
HNRNPCheterogeneous nuclear ribonucleoprotein C (C1/C2)0.119
HNRPDLheterogeneous nuclear ribonucleoprotein D-like0.114
CAND1cullin-associated and neddylation-dissociated 10.108
RBM39RNA binding motif protein 390.106
PTBP1polypyrimidine tract binding protein 10.092
QKIquaking homolog, KH domain RNA binding (mouse)0.083
ELAVL1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.066
CPEB4cytoplasmic polyadenylation element binding protein 40.061
C19orf43chromosome 19 open reading frame 430.058
PTBP2polypyrimidine tract binding protein 20.058
RBMXRNA binding motif protein, X-linked0.056
HNRNPA2B1heterogeneous nuclear ribonucleoprotein A2/B10.041
PRPF38APRP38 pre-mRNA processing factor 38 (yeast) domain containing A0.040
HNRNPKheterogeneous nuclear ribonucleoprotein K0.040
HNRNPFheterogeneous nuclear ribonucleoprotein F0.038
RBM10RNA binding motif protein 100.038
SRSF4serine/arginine-rich splicing factor 40.036
HNRNPA3heterogeneous nuclear ribonucleoprotein A30.035
SREK1splicing regulatory glutamine/lysine-rich protein 10.034
SRRTserrate RNA effector molecule homolog (Arabidopsis)0.030
CPEB3cytoplasmic polyadenylation element binding protein 30.028
RBFOX2RNA binding protein, fox-1 homolog (C. elegans) 20.027
SRSF10serine/arginine-rich splicing factor 100.026
ILF3interleukin enhancer binding factor 3, 90kDa0.024
HNRNPUL1heterogeneous nuclear ribonucleoprotein U-like 10.024
HNRNPDheterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)0.024
EEDembryonic ectoderm development0.023
H3F3BH3 histone, family 3B (H3.3B)0.022
HNRNPH2heterogeneous nuclear ribonucleoprotein H2 (H')0.021
SRSF9serine/arginine-rich splicing factor 90.018
USP22ubiquitin specific peptidase 220.017
CELF1CUGBP, Elav-like family member 10.015
MATR3matrin 30.015
ARGLU1arginine and glutamate rich 10.015
MAT2Amethionine adenosyltransferase II, alpha0.014
SONSON DNA binding protein0.013
CPSF6cleavage and polyadenylation specific factor 6, 68kDa0.013
LUC7LLUC7-like (S. cerevisiae)0.012
RAB8BRAB8B, member RAS oncogene family0.012
TARDBPTAR DNA binding protein0.012
MAGOHmago-nashi homolog, proliferation-associated (Drosophila)0.011
LUC7L2LUC7-like 2 (S. cerevisiae)0.011
ABCF3ATP-binding cassette, sub-family F (GCN20), member 30.011
SF3B4splicing factor 3b, subunit 4, 49kDa0.010
HNRNPA0heterogeneous nuclear ribonucleoprotein A00.010
PABPN1poly(A) binding protein, nuclear 10.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
YNL305Chypothetical protein0.031
YLR149Chypothetical protein0.030
YBR241Chypothetical protein0.023
YMR196Whypothetical protein0.023
YIL077Chypothetical protein0.011