The network for 'positive regulation of cytokine secretion involved in immune response' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of cytokine secretion involved in immune response

Any process that activates or increases the frequency, rate, or extent of cytokine secretion contributing to an immune response.

NameDescriptionProbabilityFunc Analog Organism
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.941
Tnftumor necrosis factor0.752
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.520
Ltalymphotoxin A0.263
Tnfsf11tumor necrosis factor (ligand) superfamily, member 110.247
Il1r1interleukin 1 receptor, type I0.220
Kdrkinase insert domain protein receptor0.192
Ror2receptor tyrosine kinase-like orphan receptor 20.188
Ifnginterferon gamma0.180
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.173
Ighimmunoglobulin heavy chain complex0.133
Nos2nitric oxide synthase 2, inducible0.130
Traf2TNF receptor-associated factor 20.115
BtkBruton agammaglobulinemia tyrosine kinase0.107
Il6interleukin 60.103
Map3k14mitogen-activated protein kinase kinase kinase 140.094
Traf6TNF receptor-associated factor 60.093
Ccl2chemokine (C-C motif) ligand 20.086
Ptgs2prostaglandin-endoperoxide synthase 20.080
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.076
Cd79aCD79A antigen (immunoglobulin-associated alpha)0.074
Bcl3B-cell leukemia/lymphoma 30.051
Tekendothelial-specific receptor tyrosine kinase0.050
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.050
S1pr2sphingosine-1-phosphate receptor 20.045
Dact1dapper homolog 1, antagonist of beta-catenin (xenopus)0.044
Shesrc homology 2 domain-containing transforming protein E0.038
Esamendothelial cell-specific adhesion molecule0.038
Pcsk5proprotein convertase subtilisin/kexin type 50.037
Ptprbprotein tyrosine phosphatase, receptor type, B0.036
Grb7growth factor receptor bound protein 70.033
Cdh5cadherin 50.031
Il1rninterleukin 1 receptor antagonist0.031
Myd88myeloid differentiation primary response gene 880.028
Spp1secreted phosphoprotein 10.028
Il10interleukin 100.028
Myct1myc target 10.027
Sox18SRY-box containing gene 180.027
Socs1suppressor of cytokine signaling 10.027
Tnfrsf11atumor necrosis factor receptor superfamily, member 11a0.026
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.026
Prkcdprotein kinase C, delta0.025
Gucy1b3guanylate cyclase 1, soluble, beta 30.024
Adcy4adenylate cyclase 40.023
Bcl6B-cell leukemia/lymphoma 60.023
Rasip1Ras interacting protein 10.022
Tlr4toll-like receptor 40.021
Clec14aC-type lectin domain family 14, member a0.021
Inpp5dinositol polyphosphate-5-phosphatase D0.020
Ccl4chemokine (C-C motif) ligand 40.019
Tnfrsf9tumor necrosis factor receptor superfamily, member 90.019
Ephb4Eph receptor B40.019
Batf3basic leucine zipper transcription factor, ATF-like 30.018
Flt4FMS-like tyrosine kinase 40.018
Icam2intercellular adhesion molecule 20.018
Slc9a3r2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.018
Cd19CD19 antigen0.017
Grb2growth factor receptor bound protein 20.017
Cxcl13chemokine (C-X-C motif) ligand 130.017
Eltd1EGF, latrophilin seven transmembrane domain containing 10.017
Cd40lgCD40 ligand0.016
Cldn5claudin 50.016
Cd40CD40 antigen0.016
Gab1growth factor receptor bound protein 2-associated protein 10.016
Sdprserum deprivation response0.016
Sprr1asmall proline-rich protein 1A0.015
Zfp36zinc finger protein 360.015
Ltblymphotoxin B0.014
Aplnrapelin receptor0.014
FasFas (TNF receptor superfamily member 6)0.013
Ciitaclass II transactivator0.013
Plauplasminogen activator, urokinase0.013
Tie1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.013
Ubdubiquitin D0.013
Gimap1GTPase, IMAP family member 10.013
Siglecesialic acid binding Ig-like lectin E0.013
Pecam1platelet/endothelial cell adhesion molecule 10.013
Birc3baculoviral IAP repeat-containing 30.012
Irg1immunoresponsive gene 10.012
Ramp2receptor (calcitonin) activity modifying protein 20.012
Mmrn2multimerin 20.012
Egfl7EGF-like domain 70.012
Sfrp1secreted frizzled-related protein 10.012
Mx2myxovirus (influenza virus) resistance 20.011
Grb14growth factor receptor bound protein 140.011
Il12binterleukin 12b0.011
Vegfavascular endothelial growth factor A0.011
Ushbp1Usher syndrome 1C binding protein 10.011
Prss30protease, serine, 300.011
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.011
Bcl6bB-cell CLL/lymphoma 6, member B0.010
Tmem204transmembrane protein 2040.010
Csf1colony stimulating factor 1 (macrophage)0.010
Naalad2N-acetylated alpha-linked acidic dipeptidase 20.010
Tnfrsf4tumor necrosis factor receptor superfamily, member 40.010
Icosinducible T-cell co-stimulator0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ANGPT2angiopoietin 20.916
ANGPT1angiopoietin 10.422
CAV1caveolin 1, caveolae protein, 22kDa0.384
TRAF5TNF receptor-associated factor 50.362
TRAF2TNF receptor-associated factor 20.276
TNFSF14tumor necrosis factor (ligand) superfamily, member 140.228
TRAF1TNF receptor-associated factor 10.172
LRP6low density lipoprotein receptor-related protein 60.070
FZD1frizzled homolog 1 (Drosophila)0.056
ZBTB48zinc finger and BTB domain containing 480.047
CAV2caveolin 20.042
TIE1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.033
TRADDTNFRSF1A-associated via death domain0.028
CD40CD40 molecule, TNF receptor superfamily member 50.026
INADLInaD-like (Drosophila)0.023
PTPRBprotein tyrosine phosphatase, receptor type, B0.023
ANGPT4angiopoietin 40.018
PTPRFprotein tyrosine phosphatase, receptor type, F0.017
PROCRprotein C receptor, endothelial0.017
TNFRSF1Btumor necrosis factor receptor superfamily, member 1B0.017
CD27CD27 molecule0.016
ID1inhibitor of DNA binding 1, dominant negative helix-loop-helix protein0.015
TXNRD1thioredoxin reductase 10.014
FZD8frizzled homolog 8 (Drosophila)0.014
SDPRserum deprivation response0.014
BTLAB and T lymphocyte associated0.013
GJA1gap junction protein, alpha 1, 43kDa0.013
TNFRSF9tumor necrosis factor receptor superfamily, member 90.012
FLT3LGfms-related tyrosine kinase 3 ligand0.012
TIFATRAF-interacting protein with forkhead-associated domain0.012
BIRC3baculoviral IAP repeat containing 30.011
SLAMF1signaling lymphocytic activation molecule family member 10.010
TFPItissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)0.010
TNFRSF11Atumor necrosis factor receptor superfamily, member 11a, NFKB activator0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism