Process View
The network for 'regulation of dopamine uptake involved in synaptic transmission' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Any process that modulates the frequency, rate or extent of the directed movement of the catecholamine neurotransmitter dopamine into a cell.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Slc6a3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 0.922 | |
Lepr | leptin receptor | 0.728 | |
Nos1 | nitric oxide synthase 1, neuronal | 0.397 | |
Drd2 | dopamine receptor D2 | 0.342 | |
Lhx3 | LIM homeobox protein 3 | 0.257 | |
Esr1 | estrogen receptor 1 (alpha) | 0.228 | |
Fshr | follicle stimulating hormone receptor | 0.211 | |
Grin1 | glutamate receptor, ionotropic, NMDA1 (zeta 1) | 0.197 | |
Slc18a2 | solute carrier family 18 (vesicular monoamine), member 2 | 0.151 | |
Drd1a | dopamine receptor D1A | 0.127 | |
Cnr1 | cannabinoid receptor 1 (brain) | 0.105 | |
Oprm1 | opioid receptor, mu 1 | 0.100 | |
Pgr | progesterone receptor | 0.093 | |
Ntrk2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.092 | |
Wt1 | Wilms tumor 1 homolog | 0.091 | |
Keg1 | kidney expressed gene 1 | 0.080 | |
Ar | androgen receptor | 0.080 | |
Prlr | prolactin receptor | 0.073 | |
Cd151 | CD151 antigen | 0.067 | |
Cacna1b | calcium channel, voltage-dependent, N type, alpha 1B subunit | 0.066 | |
Ret | ret proto-oncogene | 0.053 | |
Kl | klotho | 0.050 | |
Emx1 | empty spiracles homolog 1 (Drosophila) | 0.045 | |
Lep | leptin | 0.045 | |
Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.043 | |
Nos3 | nitric oxide synthase 3, endothelial cell | 0.043 | |
Smpd3 | sphingomyelin phosphodiesterase 3, neutral | 0.040 | |
Gfra1 | glial cell line derived neurotrophic factor family receptor alpha 1 | 0.039 | |
Vdr | vitamin D receptor | 0.036 | |
Irs2 | insulin receptor substrate 2 | 0.035 | |
Ache | acetylcholinesterase | 0.033 | |
Ghr | growth hormone receptor | 0.032 | |
Esr2 | estrogen receptor 2 (beta) | 0.032 | |
Vegfa | vascular endothelial growth factor A | 0.031 | |
Thrb | thyroid hormone receptor beta | 0.031 | |
Dlg4 | discs, large homolog 4 (Drosophila) | 0.031 | |
Adora2a | adenosine A2a receptor | 0.028 | |
Prop1 | paired like homeodomain factor 1 | 0.028 | |
Cyp19a1 | cytochrome P450, family 19, subfamily a, polypeptide 1 | 0.027 | |
Pomc | pro-opiomelanocortin-alpha | 0.027 | |
Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.027 | |
Pitx3 | paired-like homeodomain transcription factor 3 | 0.027 | |
Col4a3 | collagen, type IV, alpha 3 | 0.026 | |
Lama5 | laminin, alpha 5 | 0.024 | |
Gcgr | glucagon receptor | 0.023 | |
Plau | plasminogen activator, urokinase | 0.023 | |
Cga | glycoprotein hormones, alpha subunit | 0.023 | |
Npy2r | neuropeptide Y receptor Y2 | 0.023 | |
Crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) | 0.023 | |
Nphs2 | nephrosis 2 homolog, podocin (human) | 0.023 | |
Gnao1 | guanine nucleotide binding protein, alpha O | 0.022 | |
Sult4a1 | sulfotransferase family 4A, member 1 | 0.022 | |
Klk6 | kallikrein related-peptidase 6 | 0.021 | |
Wwox | WW domain-containing oxidoreductase | 0.021 | |
Slc30a3 | solute carrier family 30 (zinc transporter), member 3 | 0.021 | |
Gal | galanin | 0.021 | |
Vhl | von Hippel-Lindau tumor suppressor | 0.021 | |
Akr1c21 | aldo-keto reductase family 1, member C21 | 0.020 | |
Kit | kit oncogene | 0.020 | |
Tshr | thyroid stimulating hormone receptor | 0.020 | |
Ubxn10 | UBX domain protein 10 | 0.019 | |
Hba-a2 | hemoglobin alpha, adult chain 2 | 0.019 | |
Cplx2 | complexin 2 | 0.019 | |
Alas2 | aminolevulinic acid synthase 2, erythroid | 0.018 | |
Prl | prolactin | 0.018 | |
Agtr2 | angiotensin II receptor, type 2 | 0.018 | |
Col4a4 | collagen, type IV, alpha 4 | 0.018 | |
Npy1r | neuropeptide Y receptor Y1 | 0.018 | |
Fam164c | family with sequence similarity 164, member C | 0.017 | |
Chrnb2 | cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) | 0.017 | |
Sstr4 | somatostatin receptor 4 | 0.016 | |
Doc2b | double C2, beta | 0.016 | |
Bcl2 | B-cell leukemia/lymphoma 2 | 0.016 | |
Plp1 | proteolipid protein (myelin) 1 | 0.016 | |
Nt5e | 5' nucleotidase, ecto | 0.016 | |
Hbb-b2 | hemoglobin, beta adult minor chain | 0.016 | |
BC089491 | cDNA sequence BC089491 | 0.016 | |
Snap25 | synaptosomal-associated protein 25 | 0.015 | |
Cckbr | cholecystokinin B receptor | 0.015 | |
Ptprn | protein tyrosine phosphatase, receptor type, N | 0.015 | |
Gng3 | guanine nucleotide binding protein (G protein), gamma 3 | 0.015 | |
Sstr2 | somatostatin receptor 2 | 0.015 | |
Olfr16 | olfactory receptor 16 | 0.014 | |
Ihh | Indian hedgehog | 0.014 | |
Pcsk1n | proprotein convertase subtilisin/kexin type 1 inhibitor | 0.014 | |
Acsm2 | acyl-CoA synthetase medium-chain family member 2 | 0.014 | |
Sh3kbp1 | SH3-domain kinase binding protein 1 | 0.014 | |
Bai1 | brain-specific angiogenesis inhibitor 1 | 0.014 | |
Drd3 | dopamine receptor D3 | 0.014 | |
Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.014 | |
Itga3 | integrin alpha 3 | 0.014 | |
Snca | synuclein, alpha | 0.014 | |
Gpr27 | G protein-coupled receptor 27 | 0.014 | |
C1ql1 | complement component 1, q subcomponent-like 1 | 0.013 | |
Cdkn2c | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.013 | |
Ank1 | ankyrin 1, erythroid | 0.013 | |
Plcb1 | phospholipase C, beta 1 | 0.013 | |
Ugt2a3 | UDP glucuronosyltransferase 2 family, polypeptide A3 | 0.013 | |
Fosb | FBJ osteosarcoma oncogene B | 0.013 | |
Nat8 | N-acetyltransferase 8 (GCN5-related, putative) | 0.013 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
TOR1AIP2 | torsin A interacting protein 2 | 0.966 | |
SLC6A3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 0.830 | |
ADORA2A | adenosine A2a receptor | 0.806 | |
PPP1R9B | protein phosphatase 1, regulatory (inhibitor) subunit 9B | 0.766 | |
COPS4 | COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) | 0.722 | |
TOR1A | torsin family 1, member A (torsin A) | 0.581 | |
TOR1B | torsin family 1, member B (torsin B) | 0.342 | |
APLP1 | amyloid beta (A4) precursor-like protein 1 | 0.217 | |
TPPP | tubulin polymerization promoting protein | 0.160 | |
MAPT | microtubule-associated protein tau | 0.145 | |
SNCAIP | synuclein, alpha interacting protein | 0.101 | |
CNIH4 | cornichon homolog 4 (Drosophila) | 0.063 | |
MAST1 | microtubule associated serine/threonine kinase 1 | 0.042 | |
APP | amyloid beta (A4) precursor protein | 0.026 | |
SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.025 | |
TOR1AIP1 | torsin A interacting protein 1 | 0.025 | |
DOCK7 | dedicator of cytokinesis 7 | 0.024 | |
SYN1 | synapsin I | 0.020 | |
LRRK2 | leucine-rich repeat kinase 2 | 0.019 | |
HNF4A | hepatocyte nuclear factor 4, alpha | 0.019 | |
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.018 | |
RIMS1 | regulating synaptic membrane exocytosis 1 | 0.018 | |
RIMS2 | regulating synaptic membrane exocytosis 2 | 0.016 | |
HSPA1B | heat shock 70kDa protein 1B | 0.016 | |
ADRA1B | adrenergic, alpha-1B-, receptor | 0.015 | |
PCDHA4 | protocadherin alpha 4 | 0.015 | |
NAMPT | nicotinamide phosphoribosyltransferase | 0.013 | |
NCS1 | neuronal calcium sensor 1 | 0.013 | |
TOR3A | torsin family 3, member A | 0.013 | |
RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 | 0.012 | |
MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.012 | |
DHCR7 | 7-dehydrocholesterol reductase | 0.012 | |
TM9SF1 | transmembrane 9 superfamily member 1 | 0.011 | |
PRDM12 | PR domain containing 12 | 0.011 | |
GSK3B | glycogen synthase kinase 3 beta | 0.011 | |
SLC30A3 | solute carrier family 30 (zinc transporter), member 3 | 0.011 | |
SDF2 | stromal cell-derived factor 2 | 0.011 | |
NECAB2 | N-terminal EF-hand calcium binding protein 2 | 0.010 | |
TMEM59L | transmembrane protein 59-like | 0.010 |