The network for 'negative regulation of macrophage chemotaxis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of macrophage chemotaxis

Any process that decreases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.

NameDescriptionProbabilityFunc Analog Organism
Col6a2collagen, type VI, alpha 20.432
Ccl2chemokine (C-C motif) ligand 20.226
Tlr4toll-like receptor 40.214
Fbn1fibrillin 10.195
Il1rninterleukin 1 receptor antagonist0.168
Loxl1lysyl oxidase-like 10.140
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.127
Clec4dC-type lectin domain family 4, member d0.118
Loxlysyl oxidase0.114
Il6interleukin 60.092
Ccl7chemokine (C-C motif) ligand 70.075
Col1a2collagen, type I, alpha 20.074
Ccr2chemokine (C-C motif) receptor 20.073
C5ar1complement component 5a receptor 10.072
Cxcl2chemokine (C-X-C motif) ligand 20.061
Msr1macrophage scavenger receptor 10.058
Ltbp2latent transforming growth factor beta binding protein 20.053
C3ar1complement component 3a receptor 10.051
Selpselectin, platelet0.051
S100a8S100 calcium binding protein A8 (calgranulin A)0.049
Slpisecretory leukocyte peptidase inhibitor0.045
Il1binterleukin 1 beta0.041
Thbs2thrombospondin 20.040
S100a9S100 calcium binding protein A9 (calgranulin B)0.039
Mfap5microfibrillar associated protein 50.034
Cd248CD248 antigen, endosialin0.034
Saa3serum amyloid A 30.032
Leprel2leprecan-like 20.032
Bgnbiglycan0.032
Col1a1collagen, type I, alpha 10.032
Ccr1chemokine (C-C motif) receptor 10.032
Irg1immunoresponsive gene 10.031
Gpx7glutathione peroxidase 70.031
Olr1oxidized low density lipoprotein (lectin-like) receptor 10.030
Ltbp3latent transforming growth factor beta binding protein 30.030
Fpr2formyl peptide receptor 20.030
Dptdermatopontin0.029
Timp1tissue inhibitor of metalloproteinase 10.028
Col6a1collagen, type VI, alpha 10.028
Mmp3matrix metallopeptidase 30.027
Ccl3chemokine (C-C motif) ligand 30.027
Srpxsushi-repeat-containing protein0.027
Cdh11cadherin 110.027
Chi3l3chitinase 3-like 30.027
Slfn4schlafen 40.026
Il10interleukin 100.026
Plauplasminogen activator, urokinase0.026
Cxcl1chemokine (C-X-C motif) ligand 10.025
Ch25hcholesterol 25-hydroxylase0.024
Aebp1AE binding protein 10.024
Clec4eC-type lectin domain family 4, member e0.024
Mfap4microfibrillar-associated protein 40.023
Cul7cullin 70.022
Il1r2interleukin 1 receptor, type II0.022
Cd44CD44 antigen0.022
Col3a1collagen, type III, alpha 10.021
Mmp2matrix metallopeptidase 20.021
Ptgirprostaglandin I receptor (IP)0.021
Platplasminogen activator, tissue0.020
Adam8a disintegrin and metallopeptidase domain 80.019
Emilin1elastin microfibril interfacer 10.019
C1qtnf1C1q and tumor necrosis factor related protein 10.019
Twist1twist homolog 1 (Drosophila)0.019
Fkbp10FK506 binding protein 100.018
Cxcl5chemokine (C-X-C motif) ligand 50.018
Wisp1WNT1 inducible signaling pathway protein 10.018
Ctskcathepsin K0.018
Cd14CD14 antigen0.018
B3gnt9-psUDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9, pseudogene0.018
Lcn2lipocalin 20.018
Ccl17chemokine (C-C motif) ligand 170.017
Snai1snail homolog 1 (Drosophila)0.017
Il18rapinterleukin 18 receptor accessory protein0.017
Col5a1collagen, type V, alpha 10.017
Col6a3collagen, type VI, alpha 30.017
Adamts2a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20.017
Rcn3reticulocalbin 3, EF-hand calcium binding domain0.017
Tnfrsf11btumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)0.016
Svep1sushi, von Willebrand factor type A, EGF and pentraxin domain containing 10.016
Il3rainterleukin 3 receptor, alpha chain0.016
Slc10a6solute carrier family 10 (sodium/bile acid cotransporter family), member 60.016
Ngpneutrophilic granule protein0.016
Inhbainhibin beta-A0.016
Plaurplasminogen activator, urokinase receptor0.015
Myo1fmyosin IF0.015
Seleselectin, endothelial cell0.015
Mmp12matrix metallopeptidase 120.015
Pcolceprocollagen C-endopeptidase enhancer protein0.014
Gpnmbglycoprotein (transmembrane) nmb0.014
Mxra8matrix-remodelling associated 80.014
Htra3HtrA serine peptidase 30.014
MrgprfMAS-related GPR, member F0.014
Eregepiregulin0.014
Ccl12chemokine (C-C motif) ligand 120.014
Ccl4chemokine (C-C motif) ligand 40.013
Col16a1collagen, type XVI, alpha 10.013
Fpr1formyl peptide receptor 10.013
Col5a2collagen, type V, alpha 20.013
Ccl8chemokine (C-C motif) ligand 80.013
Serpinb2serine (or cysteine) peptidase inhibitor, clade B, member 20.013
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
APOEapolipoprotein E0.269
TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)0.019
CFHcomplement factor H0.015
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism