The network for 'positive regulation of cytokine production involved in immune response' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of cytokine production involved in immune response

Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response.

NameDescriptionProbabilityFunc Analog Organism
Tnftumor necrosis factor0.962
Ccl2chemokine (C-C motif) ligand 20.955
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.900
Il10interleukin 100.725
Cd40CD40 antigen0.713
Ccr2chemokine (C-C motif) receptor 20.682
Tnfaip3tumor necrosis factor, alpha-induced protein 30.472
Cd14CD14 antigen0.403
Traf6TNF receptor-associated factor 60.334
Ltalymphotoxin A0.333
Lyz2lysozyme 20.321
Ikbkginhibitor of kappaB kinase gamma0.297
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.272
H2-Aahistocompatibility 2, class II antigen A, alpha0.224
Cxcl2chemokine (C-X-C motif) ligand 20.206
Map3k7mitogen-activated protein kinase kinase kinase 70.197
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.196
Birc3baculoviral IAP repeat-containing 30.191
Fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.183
Map3k14mitogen-activated protein kinase kinase kinase 140.178
Spp1secreted phosphoprotein 10.171
Ccr1chemokine (C-C motif) receptor 10.168
Tnfrsf11atumor necrosis factor receptor superfamily, member 11a0.167
Myd88myeloid differentiation primary response gene 880.157
Il1r1interleukin 1 receptor, type I0.156
Cd44CD44 antigen0.154
Tlr2toll-like receptor 20.154
Apoeapolipoprotein E0.145
Ifnginterferon gamma0.145
Irg1immunoresponsive gene 10.129
Ptgs2prostaglandin-endoperoxide synthase 20.125
Ccl7chemokine (C-C motif) ligand 70.125
Ubdubiquitin D0.121
Ccl4chemokine (C-C motif) ligand 40.120
Ptprcprotein tyrosine phosphatase, receptor type, C0.118
Ccr5chemokine (C-C motif) receptor 50.112
Tnfsf11tumor necrosis factor (ligand) superfamily, member 110.112
Cxcl13chemokine (C-X-C motif) ligand 130.107
C3complement component 30.106
Mmp12matrix metallopeptidase 120.101
BtkBruton agammaglobulinemia tyrosine kinase0.100
Fcgr1Fc receptor, IgG, high affinity I0.100
Ccl12chemokine (C-C motif) ligand 120.099
Ccl3chemokine (C-C motif) ligand 30.098
Tnfrsf13btumor necrosis factor receptor superfamily, member 13b0.096
H2-Eb1histocompatibility 2, class II antigen E beta0.095
Ccl22chemokine (C-C motif) ligand 220.093
Ccl8chemokine (C-C motif) ligand 80.091
Ikbkbinhibitor of kappaB kinase beta0.091
C3ar1complement component 3a receptor 10.086
Il1rninterleukin 1 receptor antagonist0.085
Casp4caspase 4, apoptosis-related cysteine peptidase0.082
Il1binterleukin 1 beta0.081
Il2rginterleukin 2 receptor, gamma chain0.078
H2-Ab1histocompatibility 2, class II antigen A, beta 10.076
Dact1dapper homolog 1, antagonist of beta-catenin (xenopus)0.066
Vdrvitamin D receptor0.064
Pard3par-3 (partitioning defective 3) homolog (C. elegans)0.063
Siglecesialic acid binding Ig-like lectin E0.063
Clec4nC-type lectin domain family 4, member n0.062
Pdcd1lg2programmed cell death 1 ligand 20.060
Hcsthematopoietic cell signal transducer0.058
Msr1macrophage scavenger receptor 10.058
Cxcl9chemokine (C-X-C motif) ligand 90.055
Folr2folate receptor 2 (fetal)0.054
TcraT-cell receptor alpha chain0.053
Lag3lymphocyte-activation gene 30.051
Irf7interferon regulatory factor 70.051
Mmp13matrix metallopeptidase 130.051
Tnfsf14tumor necrosis factor (ligand) superfamily, member 140.051
Cxcl10chemokine (C-X-C motif) ligand 100.050
Ccr7chemokine (C-C motif) receptor 70.049
Itgaxintegrin alpha X0.049
Cd28CD28 antigen0.048
S1pr2sphingosine-1-phosphate receptor 20.047
Gzmagranzyme A0.046
Ltblymphotoxin B0.046
Ctswcathepsin W0.045
Il7rinterleukin 7 receptor0.044
Akt1thymoma viral proto-oncogene 10.043
Fcgr3Fc receptor, IgG, low affinity III0.041
Csf1colony stimulating factor 1 (macrophage)0.040
Nos2nitric oxide synthase 2, inducible0.040
Ch25hcholesterol 25-hydroxylase0.039
Slamf8SLAM family member 80.036
AF251705cDNA sequence AF2517050.035
Ppargperoxisome proliferator activated receptor gamma0.035
Il2rbinterleukin 2 receptor, beta chain0.034
Slc12a6solute carrier family 12, member 60.034
Socs1suppressor of cytokine signaling 10.034
Zbp1Z-DNA binding protein 10.034
Casp1caspase 10.034
Emr1EGF-like module containing, mucin-like, hormone receptor-like sequence 10.033
Cd33CD33 antigen0.033
Clec7aC-type lectin domain family 7, member a0.033
Ilkintegrin linked kinase0.032
Irak1interleukin-1 receptor-associated kinase 10.030
Slamf9SLAM family member 90.030
Cx3cr1chemokine (C-X3-C) receptor 10.029
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.028
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
TAB2TGF-beta activated kinase 1/MAP3K7 binding protein 20.704
RIPK2receptor-interacting serine-threonine kinase 20.373
TRAF3TNF receptor-associated factor 30.057
TRAF2TNF receptor-associated factor 20.053
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.053
TRAF5TNF receptor-associated factor 50.053
TRAF1TNF receptor-associated factor 10.049
CD40CD40 molecule, TNF receptor superfamily member 50.043
HLA-DRAmajor histocompatibility complex, class II, DR alpha0.028
SQSTM1sequestosome 10.022
ANGPT2angiopoietin 20.018
ANGPT1angiopoietin 10.015
TNFRSF14tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)0.015
TRADDTNFRSF1A-associated via death domain0.014
BIRC3baculoviral IAP repeat containing 30.014
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.012
ZMYND11zinc finger, MYND-type containing 110.011
TICAM2toll-like receptor adaptor molecule 20.011
TRAF6TNF receptor-associated factor 60.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Arid4aAT rich interactive domain 4A (Rbp1 like)0.016
C1qacomplement component 1, q subcomponent, A chain0.013
LOC100361917hypothetical protein LOC1003619170.012
Zp1zona pellucida glycoprotein 1 (sperm receptor)0.011
Mipmajor intrinsic protein of lens fiber0.011
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.011
Eif6eukaryotic translation initiation factor 60.010
P2rx3purinergic receptor P2X, ligand-gated ion channel, 30.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism