The network for 'trna wobble uridine modification' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

trna wobble uridine modification

The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified.

NameDescriptionProbabilityFunc Analog Organism
Mrps18bmitochondrial ribosomal protein S18B0.514
Ddx41DEAD (Asp-Glu-Ala-Asp) box polypeptide 410.292
Eftud2elongation factor Tu GTP binding domain containing 20.183
Vps25vacuolar protein sorting 25 (yeast)0.167
Per1period homolog 1 (Drosophila)0.150
Ddx56DEAD (Asp-Glu-Ala-Asp) box polypeptide 560.145
Nononon-POU-domain-containing, octamer binding protein0.137
Noc4lnucleolar complex associated 4 homolog (S. cerevisiae)0.136
Drg1developmentally regulated GTP binding protein 10.127
Anapc2anaphase promoting complex subunit 20.117
Sox4SRY-box containing gene 40.095
Cpsf3cleavage and polyadenylation specificity factor 30.091
Nudt16l1nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 10.090
Prpf6PRP6 pre-mRNA splicing factor 6 homolog (yeast)0.085
Ube2g1ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans)0.082
Parnpoly(A)-specific ribonuclease (deadenylation nuclease)0.076
Zfp740zinc finger protein 7400.070
Asna1arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)0.067
Mrps23mitochondrial ribosomal protein S230.065
Dus1ldihydrouridine synthase 1-like (S. cerevisiae)0.064
Glg1golgi apparatus protein 10.063
Jagn1jagunal homolog 1 (Drosophila)0.057
Anapc4anaphase promoting complex subunit 40.056
Rrp1ribosomal RNA processing 1 homolog (S. cerevisiae)0.052
Ppp1r7protein phosphatase 1, regulatory (inhibitor) subunit 70.050
0610010K14RikRIKEN cDNA 0610010K14 gene0.048
Ppp1caprotein phosphatase 1, catalytic subunit, alpha isoform0.048
Wdr74WD repeat domain 740.047
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.046
Impad1inositol monophosphatase domain containing 10.046
Pnkppolynucleotide kinase 3'- phosphatase0.045
Hnrnprheterogeneous nuclear ribonucleoprotein R0.045
Drg2developmentally regulated GTP binding protein 20.044
Snap47synaptosomal-associated protein, 470.044
Hif1ahypoxia inducible factor 1, alpha subunit0.044
Sec13SEC13 homolog (S. cerevisiae)0.044
Dhx30DEAH (Asp-Glu-Ala-His) box polypeptide 300.043
2610027L16RikRIKEN cDNA 2610027L16 gene0.043
Pafah1b2platelet-activating factor acetylhydrolase, isoform 1b, subunit 20.042
Ppp2caprotein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform0.042
Cdk4cyclin-dependent kinase 40.041
Atpaf2ATP synthase mitochondrial F1 complex assembly factor 20.041
Parlpresenilin associated, rhomboid-like0.039
Vps16vacuolar protein sorting 16 (yeast)0.037
Psmd4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.037
Ssr2signal sequence receptor, beta0.037
Elp2elongation protein 2 homolog (S. cerevisiae)0.037
Commd4COMM domain containing 40.037
Elp3elongation protein 3 homolog (S. cerevisiae)0.036
Mrpl37mitochondrial ribosomal protein L370.036
Psmc4proteasome (prosome, macropain) 26S subunit, ATPase, 40.035
Psmd8proteasome (prosome, macropain) 26S subunit, non-ATPase, 80.035
Varsvalyl-tRNA synthetase0.034
Fbxw11F-box and WD-40 domain protein 110.034
D10Wsu52eDNA segment, Chr 10, Wayne State University 52, expressed0.031
Eif6eukaryotic translation initiation factor 60.030
Lsg1large subunit GTPase 1 homolog (S. cerevisiae)0.030
Ercc3excision repair cross-complementing rodent repair deficiency, complementation group 30.029
Triap1TP53 regulated inhibitor of apoptosis 10.029
Zranb2zinc finger, RAN-binding domain containing 20.029
Imp4IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)0.029
Th1lTH1-like homolog (Drosophila)0.028
Usp22ubiquitin specific peptidase 220.028
Ttc3tetratricopeptide repeat domain 30.028
Pin1protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 10.026
Gartphosphoribosylglycinamide formyltransferase0.026
Gsk3bglycogen synthase kinase 3 beta0.026
Gtf2h4general transcription factor II H, polypeptide 40.026
Fam192afamily with sequence similarity 192, member A0.026
2410001C21RikRIKEN cDNA 2410001C21 gene0.026
Ppp4cprotein phosphatase 4, catalytic subunit0.026
Apex1apurinic/apyrimidinic endonuclease 10.025
Brd4bromodomain containing 40.025
Ctnnbl1catenin, beta like 10.024
Sox11SRY-box containing gene 110.024
Prpf31PRP31 pre-mRNA processing factor 31 homolog (yeast)0.024
Mcm3apminichromosome maintenance deficient 3 (S. cerevisiae) associated protein0.024
Cdc37cell division cycle 37 homolog (S. cerevisiae)0.024
Ddx39bDEAD (Asp-Glu-Ala-Asp) box polypeptide 39B0.024
Mlh1mutL homolog 1 (E. coli)0.023
Arpc4actin related protein 2/3 complex, subunit 40.023
Gins4GINS complex subunit 4 (Sld5 homolog)0.023
Eif3beukaryotic translation initiation factor 3, subunit B0.023
Ptcd2pentatricopeptide repeat domain 20.023
Pqbp1polyglutamine binding protein 10.022
Lrrc59leucine rich repeat containing 590.022
Psmd13proteasome (prosome, macropain) 26S subunit, non-ATPase, 130.022
Sept7septin 70.022
Hnrnpkheterogeneous nuclear ribonucleoprotein K0.021
Ptp4a2protein tyrosine phosphatase 4a20.021
Actr3ARP3 actin-related protein 3 homolog (yeast)0.021
Polr3apolymerase (RNA) III (DNA directed) polypeptide A0.021
Eif2b1eukaryotic translation initiation factor 2B, subunit 1 (alpha)0.021
C80913expressed sequence C809130.021
Thoc3THO complex 30.021
Ngrnneugrin, neurite outgrowth associated0.020
Stx6syntaxin 60.020
2310011J03RikRIKEN cDNA 2310011J03 gene0.020
Spag7sperm associated antigen 70.020
Lsm4LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)0.020
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
IKBKAPinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein1.000
ELP2elongation protein 2 homolog (S. cerevisiae)0.980
ELP3elongation protein 3 homolog (S. cerevisiae)0.943
FAM96Bfamily with sequence similarity 96, member B0.667
ELP4elongation protein 4 homolog (S. cerevisiae)0.609
MDM4Mdm4 p53 binding protein homolog (mouse)0.123
DVL1dishevelled, dsh homolog 1 (Drosophila)0.091
DVL3dishevelled, dsh homolog 3 (Drosophila)0.083
MMS19MMS19 nucleotide excision repair homolog (S. cerevisiae)0.057
CSNK1Ecasein kinase 1, epsilon0.055
ANKRD28ankyrin repeat domain 280.051
MAP3K7mitogen-activated protein kinase kinase kinase 70.048
PPP1R14Aprotein phosphatase 1, regulatory (inhibitor) subunit 14A0.047
PPP6R3protein phosphatase 6, regulatory subunit 30.034
OCLNoccludin0.026
HTThuntingtin0.026
ASCC2activating signal cointegrator 1 complex subunit 20.020
MYST2MYST histone acetyltransferase 20.020
CEBPECCAAT/enhancer binding protein (C/EBP), epsilon0.019
MCCmutated in colorectal cancers0.016
NIPSNAP3Anipsnap homolog 3A (C. elegans)0.015
NTHL1nth endonuclease III-like 1 (E. coli)0.014
SNAPINSNAP-associated protein0.014
MOBKL1AMOB1, Mps One Binder kinase activator-like 1A (yeast)0.013
DVL2dishevelled, dsh homolog 2 (Drosophila)0.012
KPNA1karyopherin alpha 1 (importin alpha 5)0.011
HEATR2HEAT repeat containing 20.011
CSNK1A1casein kinase 1, alpha 10.011
FAM110Afamily with sequence similarity 110, member A0.010
MAPK8mitogen-activated protein kinase 80.010
FAM110Cfamily with sequence similarity 110, member C0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
ELP6Elp6p0.999
ELP4Elp4p0.999
NCS6Ncs6p0.998
ELP3Elp3p0.997
IKI3Iki3p0.996
IKI1Iki1p0.991
KTI11Kti11p0.972
UBA4Uba4p0.856
KTI12Kti12p0.852
NCS2Ncs2p0.803
URM1Urm1p0.747
ELP2Elp2p0.683
YHR122Whypothetical protein0.674
HRR25Hrr25p0.390
NAR1Nar1p0.343
DRE2Dre2p0.270
SLM3Slm3p0.215
SIT4Sit4p0.202
NFS1Nfs1p0.171
MEX67Mex67p0.132
SUA5Sua5p0.113
SAK1Sak1p0.108
PRS2Prs2p0.107
YHR003Chypothetical protein0.093
ISD11Isd11p0.090
THG1Thg1p0.075
PUS1Pus1p0.073
ABP140Abp140p0.072
TRM9Trm9p0.063
NUP82Nup82p0.061
SRD1Srd1p0.056
ATS1Ats1p0.054
NBA1Nba1p0.054
MER1Mer1p0.054
LIP5Lip5p0.052
ARG8Arg8p0.051
GLT1Glt1p0.049
CFD1Cfd1p0.047
SFA1Sfa1p0.046
SKS1Sks1p0.045
TYW1Tyw1p0.042
ADH2Adh2p0.040
ARP10Arp10p0.040
TUM1Tum1p0.040
YFH1Yfh1p0.039
YOL038C-Ahypothetical protein0.039
LEU2Leu2p0.039
SAP190Sap190p0.038
NGL2Ngl2p0.038
YLR264C-Ahypothetical protein0.038
YCK2Yck2p0.038
MF(ALPHA)2Mf(alpha)2p0.034
YLR162Whypothetical protein0.034
SFT1Sft1p0.034
ATR1Atr1p0.034
DOG1Dog1p0.033
YPR157Whypothetical protein0.033
GDS1Gds1p0.032
YBR016Whypothetical protein0.032
YLR042Chypothetical protein0.032
SFB2Sfb2p0.032
SPL2Spl2p0.031
PFS1Pfs1p0.031
KAE1Kae1p0.030
YAR068Whypothetical protein0.030
MF(ALPHA)1Mf(alpha)1p0.030
TYE7Tye7p0.029
ZPS1Zps1p0.029
AVL9Avl9p0.029
ATP6Atp6p0.029
RNH70Rnh70p0.028
STS1Sts1p0.028
YIL151Chypothetical protein0.028
URA3Ura3p0.028
YCK1Yck1p0.027
MTO1Mto1p0.027
TRM12Trm12p0.027
YML119Whypothetical protein0.027
TAH1Tah1p0.026
PCC1Pcc1p0.025
YPL067Chypothetical protein0.025
CHA1Cha1p0.025
NEO1Neo1p0.025
DEG1Deg1p0.025
UPS3Ups3p0.025
HPF1Hpf1p0.024
MRS2Mrs2p0.024
YBT1Ybt1p0.024
DML1Dml1p0.024
NDE1Nde1p0.024
SGE1Sge1p0.024
DIC1Dic1p0.024
BIO2Bio2p0.024
YBR013Chypothetical protein0.023
YER186Chypothetical protein0.023
RAM2Ram2p0.023
PHO8Pho8p0.023
AUA1Aua1p0.023
RIB1Rib1p0.023
YIR035Chypothetical protein0.022