The network for 'positive regulation of striated muscle contraction' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of striated muscle contraction

Any process that activates or increases the frequency, rate or extent of striated muscle contraction.

NameDescriptionProbabilityFunc Analog Organism
Kcnma1potassium large conductance calcium-activated channel, subfamily M, alpha member 10.416
Chordc1cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 10.393
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.315
Hsph1heat shock 105kDa/110kDa protein 10.238
Hspa8heat shock protein 80.216
Cacna1scalcium channel, voltage-dependent, L type, alpha 1S subunit0.190
Pvalbparvalbumin0.085
Hspa5heat shock protein 50.081
Itgb1bp2integrin beta 1 binding protein 20.079
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.075
Ednrbendothelin receptor type B0.074
Tmem146transmembrane protein 1460.069
Scn1asodium channel, voltage-gated, type I, alpha0.069
Actn2actinin alpha 20.064
Ppp1r9bprotein phosphatase 1, regulatory subunit 9B0.062
Casq2calsequestrin 20.060
Sparcl1SPARC-like 10.055
Cox8bcytochrome c oxidase, subunit VIIIb0.055
Cdh13cadherin 130.054
Scn5asodium channel, voltage-gated, type V, alpha0.053
Dnaja1DnaJ (Hsp40) homolog, subfamily A, member 10.052
Vamp2vesicle-associated membrane protein 20.050
Tmprss6transmembrane serine protease 60.049
Kcna1potassium voltage-gated channel, shaker-related subfamily, member 10.048
Hsp90b1heat shock protein 90, beta (Grp94), member 10.046
Hbb-b2hemoglobin, beta adult minor chain0.045
Cacybpcalcyclin binding protein0.044
Ptprbprotein tyrosine phosphatase, receptor type, B0.044
Slc4a4solute carrier family 4 (anion exchanger), member 40.043
Atp1b1ATPase, Na+/K+ transporting, beta 1 polypeptide0.041
Iqcb1IQ calmodulin-binding motif containing 10.040
Ldb3LIM domain binding 30.039
Pip4k2aphosphatidylinositol-5-phosphate 4-kinase, type II, alpha0.038
Hspd1heat shock protein 1 (chaperonin)0.037
DarcDuffy blood group, chemokine receptor0.036
Casq1calsequestrin 10.035
Ank1ankyrin 1, erythroid0.035
Abcc9ATP-binding cassette, sub-family C (CFTR/MRP), member 90.034
Gria1glutamate receptor, ionotropic, AMPA1 (alpha 1)0.034
Prkcbprotein kinase C, beta0.033
Fkbp1bFK506 binding protein 1b0.033
Cckbrcholecystokinin B receptor0.032
Ahi1Abelson helper integration site 10.032
Pygmmuscle glycogen phosphorylase0.032
Actc1actin, alpha, cardiac muscle 10.031
Nkx6-3NK6 homeobox 30.031
Gucy1b3guanylate cyclase 1, soluble, beta 30.031
Myh1myosin, heavy polypeptide 1, skeletal muscle, adult0.030
Tnnc2troponin C2, fast0.030
Akt1thymoma viral proto-oncogene 10.030
Rgs7regulator of G protein signaling 70.030
Adra1badrenergic receptor, alpha 1b0.030
Bzw1basic leucine zipper and W2 domains 10.030
Eedembryonic ectoderm development0.029
Car2carbonic anhydrase 20.029
Srpk3serine/arginine-rich protein specific kinase 30.028
Nrapnebulin-related anchoring protein0.028
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.028
Nphp4nephronophthisis 4 (juvenile) homolog (human)0.028
Trp63transformation related protein 630.027
Cacna1ccalcium channel, voltage-dependent, L type, alpha 1C subunit0.027
Pcsk4proprotein convertase subtilisin/kexin type 40.026
Kcnab2potassium voltage-gated channel, shaker-related subfamily, beta member 20.026
Kcne2potassium voltage-gated channel, Isk-related subfamily, gene 20.026
Pde1bphosphodiesterase 1B, Ca2+-calmodulin dependent0.025
Dnajb5DnaJ (Hsp40) homolog, subfamily B, member 50.025
Cntn1contactin 10.024
Cul9cullin 90.024
Fam105afamily with sequence similarity 105, member A0.024
Tnnt3troponin T3, skeletal, fast0.023
Actr3ARP3 actin-related protein 3 homolog (yeast)0.023
F3coagulation factor III0.023
Sncbsynuclein, beta0.023
Plp1proteolipid protein (myelin) 10.023
Cox6a2cytochrome c oxidase, subunit VI a, polypeptide 20.023
Htthuntingtin0.023
Cct3chaperonin containing Tcp1, subunit 3 (gamma)0.023
Ptges3prostaglandin E synthase 3 (cytosolic)0.023
Clstn1calsyntenin 10.023
Ckmt2creatine kinase, mitochondrial 20.022
Myom2myomesin 20.022
Atp2b2ATPase, Ca++ transporting, plasma membrane 20.022
Cacna2d1calcium channel, voltage-dependent, alpha2/delta subunit 10.022
Cyr61cysteine rich protein 610.022
Cadm3cell adhesion molecule 30.022
Timp3tissue inhibitor of metalloproteinase 30.021
Frmd5FERM domain containing 50.021
Ppfia4protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 40.021
Hspa4lheat shock protein 4 like0.021
Plin4perilipin 40.021
Apobec2apolipoprotein B mRNA editing enzyme, catalytic polypeptide 20.021
Lama2laminin, alpha 20.020
Zc3h15zinc finger CCCH-type containing 150.020
Nefmneurofilament, medium polypeptide0.020
Kcna2potassium voltage-gated channel, shaker-related subfamily, member 20.020
Tnni2troponin I, skeletal, fast 20.020
Myom1myomesin 10.019
Mylpfmyosin light chain, phosphorylatable, fast skeletal muscle0.019
Rasa3RAS p21 protein activator 30.019
Astn1astrotactin 10.019
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
unc-29Protein UNC-290.850
acr-8Protein ACR-80.469
lev-8Protein LEV-80.360
unc-38Protein UNC-380.242
lev-1Protein LEV-10.171
F20D6.11Protein F20D6.110.097
B0303.2Protein B0303.20.079
unc-112Protein UNC-1120.062
acr-16Protein ACR-160.061
F55H12.4Protein F55H12.40.060
abt-4Protein ABT-40.053
F54E4.3Protein F54E4.30.047
glr-5Protein GLR-50.043
C44B7.11Protein C44B7.110.043
rhr-2Protein RHR-20.042
K06A9.3Protein K06A9.30.039
F27C8.2Protein F27C8.20.038
F40A3.4Protein F40A3.40.037
frm-3Protein FRM-30.035
W03G11.3Protein W03G11.30.034
nhr-148Protein NHR-1480.033
CELE_C13A2.4Protein C13A2.40.033
snt-5Protein SNT-50.032
spon-1Protein SPON-10.030
D1009.3Protein D1009.30.030
math-4Protein MATH-40.030
mig-17Protein MIG-170.029
F08F3.10Protein F08F3.100.029
bar-1Protein BAR-10.028
tph-1Protein TPH-10.028
pept-1Protein PEPT-10.027
F44A6.3Protein F44A6.30.027
unc-7Protein UNC-70.027
W05F2.7Protein W05F2.70.026
twk-8Protein TWK-80.026
aman-1Protein AMAN-10.025
lgc-4Protein LGC-40.025
C17H11.1Protein C17H11.10.023
nhr-153Protein NHR-1530.022
CELE_K08E7.8Protein K08E7.80.022
klp-3Protein KLP-30.022
R12C12.1Protein R12C12.10.022
C06E2.1Protein C06E2.10.021
dpy-20Protein DPY-200.021
twk-34Protein TWK-340.021
sptl-3Protein SPTL-30.020
unc-103Protein UNC-1030.020
cyp-13A2Protein CYP-13A20.020
ugt-23Protein UGT-230.020
D2007.2Protein D2007.20.020
tba-8Protein TBA-80.020
ZK792.4Protein ZK792.40.020
F09A5.1Protein F09A5.10.020
F52D10.6Protein F52D10.60.020
T21E8.5Protein T21E8.50.020
F52A8.3Protein F52A8.30.019
mec-4Protein MEC-40.019
scav-6Protein SCAV-60.019
F29G6.1Protein F29G6.10.019
acr-15Protein ACR-150.019
CELE_Y32B12C.3Protein Y32B12C.30.019
C14A4.12Protein C14A4.120.019
npr-28Protein NPR-280.019
sul-1Protein SUL-10.019
H02F09.3Protein H02F09.30.019
ZK112.5Protein ZK112.50.019
Y45G12C.1Protein Y45G12C.10.019
gbb-2Protein GBB-20.018
acr-2Protein ACR-20.018
dop-2Protein DOP-20.018
glb-3Protein GLB-30.018
egl-19Protein EGL-190.018
F13H6.3Protein F13H6.30.018
F47B7.7Protein F47B7.70.017
best-3Protein BEST-30.017
trp-1Protein TRP-10.017
T05D4.3Protein T05D4.30.017
H43E16.1Protein H43E16.10.017
lgc-26Protein LGC-260.017
B0310.1Protein B0310.10.017
VC27A7L.1Protein VC27A7L.10.017
soc-2Protein SOC-20.017
CELE_F57G8.7Protein F57G8.70.017
H10E21.5Protein H10E21.50.017
ZK455.5Protein ZK455.50.017
ser-2Protein SER-20.017
ugt-11Protein UGT-110.017
ric-3Protein RIC-30.016
CELE_Y57A10A.24Protein Y57A10A.240.016
nas-29Protein NAS-290.016
F08B1.3Protein F08B1.30.016
F59F5.5Protein F59F5.50.016
nhr-147Protein NHR-1470.016
F20B6.4Protein F20B6.40.016
epg-3Protein EPG-30.016
F14F4.1Protein F14F4.10.016
CELE_R04B5.6Protein R04B5.60.016
npr-6Protein NPR-60.015
Y45F10D.6Protein Y45F10D.60.015
nhr-186Protein NHR-1860.015
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
VPS29vacuolar protein sorting 29 homolog (S. cerevisiae)0.466
BBS10Bardet-Biedl syndrome 100.195
CYR61cysteine-rich, angiogenic inducer, 610.191
FN1fibronectin 10.145
REEP5receptor accessory protein 50.126
TUBB2Btubulin, beta 2B0.079
RIN3Ras and Rab interactor 30.071
ITGA5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.066
NR4A1nuclear receptor subfamily 4, group A, member 10.037
CFTRcystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)0.036
CTSBcathepsin B0.025
AKAP6A kinase (PRKA) anchor protein 60.025
PRKACAprotein kinase, cAMP-dependent, catalytic, alpha0.023
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.020
C7orf36chromosome 7 open reading frame 360.011
FRZBfrizzled-related protein0.011
MAPK6mitogen-activated protein kinase 60.010
NR4A2nuclear receptor subfamily 4, group A, member 20.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Hsph1heat shock 105/110 protein 10.334
Hspa8heat shock protein 80.040
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.033
Hspd1heat shock protein 1 (chaperonin)0.015
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.010
Stip1stress-induced phosphoprotein 10.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism