The network for 'histone h4 acetylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

histone h4 acetylation

The modification of histone H4 by the addition of an acetyl group.

NameDescriptionProbabilityFunc Analog Organism
Trraptransformation/transcription domain-associated protein0.991
Arid1aAT rich interactive domain 1A (SWI-like)0.979
Dmap1DNA methyltransferase 1-associated protein 10.926
CrebbpCREB binding protein0.901
Ep400E1A binding protein p4000.897
Per2period homolog 2 (Drosophila)0.861
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.829
Kat5K(lysine) acetyltransferase 50.772
Trp53transformation related protein 530.710
Pou5f1POU domain, class 5, transcription factor 10.707
Ep300E1A binding protein p3000.688
Mll1myeloid/lymphoid or mixed-lineage leukemia 10.688
Ddx17DEAD (Asp-Glu-Ala-Asp) box polypeptide 170.574
Tcf4transcription factor 40.495
Brca1breast cancer 10.477
Cry2cryptochrome 2 (photolyase-like)0.439
Stat2signal transducer and activator of transcription 20.421
Clockcircadian locomotor output cycles kaput0.383
Atg12autophagy-related 12 (yeast)0.372
Tcfcp2l1transcription factor CP2-like 10.343
Kat2aK(lysine) acetyltransferase 2A0.323
Arrb2arrestin, beta 20.308
Isg15ISG15 ubiquitin-like modifier0.264
Tcf3transcription factor 30.242
Mll3myeloid/lymphoid or mixed-lineage leukemia 30.229
Arntlaryl hydrocarbon receptor nuclear translocator-like0.186
Ikzf1IKAROS family zinc finger 10.181
Smarcc1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.165
Ighimmunoglobulin heavy chain complex0.159
Rnf44ring finger protein 440.156
Tnrc6ctrinucleotide repeat containing 6C0.154
Csnk1ecasein kinase 1, epsilon0.146
Wdr5WD repeat domain 50.146
Sfpi1SFFV proviral integration 10.144
Ifit1interferon-induced protein with tetratricopeptide repeats 10.134
Sin3atranscriptional regulator, SIN3A (yeast)0.134
Polr2apolymerase (RNA) II (DNA directed) polypeptide A0.130
Rbbp5retinoblastoma binding protein 50.123
Arid2AT rich interactive domain 2 (ARID, RFX-like)0.121
Hcfc1host cell factor C10.121
Irf4interferon regulatory factor 40.118
Brd4bromodomain containing 40.111
Atmataxia telangiectasia mutated homolog (human)0.096
Esr1estrogen receptor 1 (alpha)0.095
Cbfa2t3core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)0.094
Bptfbromodomain PHD finger transcription factor0.093
Carm1coactivator-associated arginine methyltransferase 10.092
NanogNanog homeobox0.090
Arid1bAT rich interactive domain 1B (SWI-like)0.087
Ncoa3nuclear receptor coactivator 30.086
Runx1runt related transcription factor 10.080
Ldb1LIM domain binding 10.077
Irgm2immunity-related GTPase family M member 20.072
Ash2lash2 (absent, small, or homeotic)-like (Drosophila)0.071
Scaf4SR-related CTD-associated factor 40.070
Zmynd11zinc finger, MYND domain containing 110.065
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.065
Bap1Brca1 associated protein 10.063
Acin1apoptotic chromatin condensation inducer 10.062
Sox2SRY-box containing gene 20.057
Unc93b1unc-93 homolog B1 (C. elegans)0.055
MaxMax protein0.053
Axin1axin 10.052
Mycmyelocytomatosis oncogene0.051
Thrathyroid hormone receptor alpha0.050
Macf1microtubule-actin crosslinking factor 10.050
Atxn7l3ataxin 7-like 30.050
TapbpTAP binding protein0.049
Smarcc2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 20.049
Cd79bCD79B antigen0.049
Mll5myeloid/lymphoid or mixed-lineage leukemia 50.047
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.046
Cdk9cyclin-dependent kinase 9 (CDC2-related kinase)0.046
Kdm5blysine (K)-specific demethylase 5B0.046
Trp63transformation related protein 630.045
Kdm1alysine (K)-specific demethylase 1A0.045
Prpf8pre-mRNA processing factor 80.044
Myod1myogenic differentiation 10.043
Pum1pumilio 1 (Drosophila)0.043
Smad4MAD homolog 4 (Drosophila)0.041
Uba7ubiquitin-like modifier activating enzyme 70.040
Ctnnb1catenin (cadherin associated protein), beta 10.039
Tal1T-cell acute lymphocytic leukemia 10.039
Atg10autophagy-related 10 (yeast)0.037
Tmem131transmembrane protein 1310.036
Gsk3bglycogen synthase kinase 3 beta0.036
Apcadenomatosis polyposis coli0.035
Traf6TNF receptor-associated factor 60.034
Mecp2methyl CpG binding protein 20.034
Fam76bfamily with sequence similarity 76, member B0.034
Chd4chromodomain helicase DNA binding protein 40.033
Trim28tripartite motif-containing 280.033
Sf1splicing factor 10.033
Cadcarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase0.033
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.033
Smarca2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 20.032
Csnk1dcasein kinase 1, delta0.032
Tcf7transcription factor 7, T-cell specific0.031
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
PcafCG4107 gene product from transcript CG4107-RA0.914
msl-3male-specific lethal 30.875
HcfHost cell factor0.863
mod(mdg4)modifier of mdg40.833
CG10414CG10414 gene product from transcript CG10414-RA0.815
wdswill die slowly0.779
msl-2male-specific lethal 20.581
pr-set7CG3307 gene product from transcript CG3307-RC0.557
msl-1male-specific lethal 10.535
Snr1Snf5-related 10.478
Nipped-ACG33554 gene product from transcript CG33554-RE0.454
Tao-1CG14217 gene product from transcript CG14217-RF0.380
Chrac-14CG13399 gene product from transcript CG13399-RA0.349
D12CG13400 gene product from transcript CG13400-RA0.347
mofmales absent on the first0.330
Atac1ATAC component 10.320
lidlittle imaginal discs0.240
GmdGDP-mannose 4,6-dehydratase0.226
Mocs2Molybdopterin synthase 20.220
Atg1Autophagy-specific gene 10.170
dcodiscs overgrown0.164
B52CG10851 gene product from transcript CG10851-RB0.137
CG14614CG14614 gene product from transcript CG14614-RA0.125
Taf5TBP-associated factor 50.123
CTCFCG8591 gene product from transcript CG8591-RA0.123
His2AvHistone H2A variant0.111
Sgf29CG30390 gene product from transcript CG30390-RA0.105
CG10880CG10880 gene product from transcript CG10880-RA0.080
e(y)3enhancer of yellow 30.080
NC2betaCG4185 gene product from transcript CG4185-RA0.074
SceSex combs extra0.074
ash2absent, small, or homeotic discs 20.059
Su(var)3-3Suppressor of variegation 3-30.057
Saf6SAGA factor-like TAF60.055
Traf6TNF-receptor-associated factor 60.054
MRG15CG6363 gene product from transcript CG6363-RA0.054
CG16812CG16812 gene product from transcript CG16812-RA0.051
fs(1)hfemale sterile (1) homeotic0.047
Su(H)Suppressor of Hairless0.046
Hr39Hormone receptor-like in 390.046
phlpole hole0.040
SF2CG6987 gene product from transcript CG6987-RA0.039
Tango6Transport and Golgi organization 60.037
prodproliferation disrupter0.034
CSN6COP9 complex homolog subunit 60.034
Ptp69DProtein tyrosine phosphatase 69D0.034
l(3)mbtlethal (3) malignant brain tumor0.033
fendforked end0.032
CG16908CG16908 gene product from transcript CG16908-RA0.030
CG6116CG6116 gene product from transcript CG6116-RA0.028
ph-dpolyhomeotic distal0.028
Pka-C1cAMP-dependent protein kinase 10.028
CG8165CG8165 gene product from transcript CG8165-RA0.027
me31Bmaternal expression at 31B0.026
Atg7Autophagy-specific gene 70.024
ScmSex comb on midleg0.023
ash1absent, small, or homeotic discs 10.023
CG6254CG6254 gene product from transcript CG6254-RA0.022
CG5222CG5222 gene product from transcript CG5222-RA0.021
ctpcut up0.021
RASSF8CG5053 gene product from transcript CG5053-RA0.020
Eip63EEcdysone-induced protein 63E0.019
CG5694CG5694 gene product from transcript CG5694-RA0.018
CG32016CG32016 gene product from transcript CG32016-RB0.018
CG9339CG9339 gene product from transcript CG9339-RG0.017
BRWD3CG31132 gene product from transcript CG31132-RA0.016
Tip60CG6121 gene product from transcript CG6121-RA0.016
CG1347CG1347 gene product from transcript CG1347-RB0.016
Rsf1Repressor splicing factor 10.016
cdc16CG6759 gene product from transcript CG6759-RA0.015
rnh1ribonuclease H10.015
CG32343CG32343 gene product from transcript CG32343-RB0.015
CG12042CG12042 gene product from transcript CG12042-RA0.015
Taf7TBP-associated factor 70.014
Nf-YBNuclear factor Y-box B0.014
Eip75BEcdysone-induced protein 75B0.014
Mfap1Microfibril-associated protein 10.014
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
C20orf20chromosome 20 open reading frame 201.000
TP53tumor protein p531.000
CREBBPCREB binding protein0.999
BRCA1breast cancer 1, early onset0.998
RUVBL1RuvB-like 1 (E. coli)0.992
ACTL6Aactin-like 6A0.992
IKBKAPinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein0.984
TRRAPtransformation/transcription domain-associated protein0.970
EP300E1A binding protein p3000.970
MLLmyeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)0.951
SIN3ASIN3 homolog A, transcription regulator (yeast)0.947
WDR5WD repeat domain 50.923
ELP2elongation protein 2 homolog (S. cerevisiae)0.898
YY1YY1 transcription factor0.890
TADA3transcriptional adaptor 30.885
ESR1estrogen receptor 10.882
SIRT1sirtuin 10.879
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.874
KAT2BK(lysine) acetyltransferase 2B0.838
ELP3elongation protein 3 homolog (S. cerevisiae)0.825
LRP1low density lipoprotein receptor-related protein 10.789
DAXXdeath-domain associated protein0.740
NCOA2nuclear receptor coactivator 20.730
MRFAP1Morf4 family associated protein 10.705
MYST3MYST histone acetyltransferase (monocytic leukemia) 30.696
EPC2enhancer of polycomb homolog 2 (Drosophila)0.691
CCDC101coiled-coil domain containing 1010.691
ING5inhibitor of growth family, member 50.670
MLLT1myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10.626
ING3inhibitor of growth family, member 30.615
ELP4elongation protein 4 homolog (S. cerevisiae)0.586
CHEK2CHK2 checkpoint homolog (S. pombe)0.572
MDM2Mdm2 p53 binding protein homolog (mouse)0.567
ARandrogen receptor0.541
DOT1LDOT1-like, histone H3 methyltransferase (S. cerevisiae)0.530
ZNF496zinc finger protein 4960.508
KAT2AK(lysine) acetyltransferase 2A0.507
NCOA1nuclear receptor coactivator 10.490
DMAP1DNA methyltransferase 1 associated protein 10.487
HIST1H3Bhistone cluster 1, H3b0.476
MBIPMAP3K12 binding inhibitory protein 10.467
INO80INO80 homolog (S. cerevisiae)0.449
VPS72vacuolar protein sorting 72 homolog (S. cerevisiae)0.434
KAT5K(lysine) acetyltransferase 50.426
MYST1MYST histone acetyltransferase 10.410
PLEKHF2pleckstrin homology domain containing, family F (with FYVE domain) member 20.406
CCNT1cyclin T10.384
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.380
FUBP1far upstream element (FUSE) binding protein 10.379
MAP3K5mitogen-activated protein kinase kinase kinase 50.340
HIST2H3Chistone cluster 2, H3c0.257
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.248
INO80EINO80 complex subunit E0.238
SP1Sp1 transcription factor0.230
ARRB1arrestin, beta 10.227
HIST1H4Fhistone cluster 1, H4f0.211
HIC1hypermethylated in cancer 10.191
EP400E1A binding protein p4000.190
PMLpromyelocytic leukemia0.185
ATG3ATG3 autophagy related 3 homolog (S. cerevisiae)0.184
SMURF1SMAD specific E3 ubiquitin protein ligase 10.161
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.158
TAF4TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa0.158
CREBZFCREB/ATF bZIP transcription factor0.153
USP22ubiquitin specific peptidase 220.139
MEN1multiple endocrine neoplasia I0.128
UBE3Aubiquitin protein ligase E3A0.128
FOXO1forkhead box O10.127
BARD1BRCA1 associated RING domain 10.124
WRNWerner syndrome, RecQ helicase-like0.121
EPC1enhancer of polycomb homolog 1 (Drosophila)0.116
BRD8bromodomain containing 80.115
BAZ2Bbromodomain adjacent to zinc finger domain, 2B0.114
MRFAP1L1Morf4 family associated protein 1-like 10.113
DPCDdeleted in primary ciliary dyskinesia homolog (mouse)0.113
CEP70centrosomal protein 70kDa0.110
NCOA6nuclear receptor coactivator 60.106
DDX5DEAD (Asp-Glu-Ala-Asp) box polypeptide 50.105
HIPK2homeodomain interacting protein kinase 20.104
TGIF1TGFB-induced factor homeobox 10.102
MAPK10mitogen-activated protein kinase 100.101
ATMataxia telangiectasia mutated0.100
GNMTglycine N-methyltransferase0.095
HDAC1histone deacetylase 10.094
RXRAretinoid X receptor, alpha0.093
JUPjunction plakoglobin0.092
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.092
THAP11THAP domain containing 110.092
SCAF8SR-related CTD-associated factor 80.089
PIAS4protein inhibitor of activated STAT, 40.088
YEATS4YEATS domain containing 40.086
ATXN7ataxin 70.085
TCF4transcription factor 40.074
RUVBL2RuvB-like 2 (E. coli)0.072
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.071
HCFC1host cell factor C1 (VP16-accessory protein)0.069
IP6K2inositol hexakisphosphate kinase 20.067
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism