The network for 'cellular response to amino acid stimulus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular response to amino acid stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.

NameDescriptionProbabilityFunc Analog Organism
Col1a1collagen, type I, alpha 11.000
Leprleptin receptor0.999
Tnftumor necrosis factor0.999
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.998
Csf1colony stimulating factor 1 (macrophage)0.998
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.997
Col1a2collagen, type I, alpha 20.994
Col6a1collagen, type VI, alpha 10.991
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.991
Col3a1collagen, type III, alpha 10.976
Stat3signal transducer and activator of transcription 30.970
Trp53transformation related protein 530.957
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.953
Ltalymphotoxin A0.950
Ikzf1IKAROS family zinc finger 10.934
Col6a2collagen, type VI, alpha 20.931
Col4a1collagen, type IV, alpha 10.930
Map3k14mitogen-activated protein kinase kinase kinase 140.910
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.905
Col6a3collagen, type VI, alpha 30.899
Ptpn11protein tyrosine phosphatase, non-receptor type 110.881
Cpeb3cytoplasmic polyadenylation element binding protein 30.880
Apoeapolipoprotein E0.871
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.855
Col4a5collagen, type IV, alpha 50.853
Il10interleukin 100.844
Dnmt3bDNA methyltransferase 3B0.838
Col5a2collagen, type V, alpha 20.826
Ltbp2latent transforming growth factor beta binding protein 20.821
Nos3nitric oxide synthase 3, endothelial cell0.786
Dnmt3aDNA methyltransferase 3A0.782
Col4a2collagen, type IV, alpha 20.777
Mtormechanistic target of rapamycin (serine/threonine kinase)0.754
Col11a1collagen, type XI, alpha 10.744
Il6interleukin 60.739
Tnfsf11tumor necrosis factor (ligand) superfamily, member 110.734
Ifnginterferon gamma0.682
Il6stinterleukin 6 signal transducer0.679
Itgb1integrin beta 1 (fibronectin receptor beta)0.630
Plcg1phospholipase C, gamma 10.630
Fbn1fibrillin 10.606
Mmp2matrix metallopeptidase 20.569
Jak2Janus kinase 20.523
Ltbp3latent transforming growth factor beta binding protein 30.513
Neurl1aneuralized homolog 1A (Drosophila)0.511
Ldlrlow density lipoprotein receptor0.506
Vegfavascular endothelial growth factor A0.493
Srpxsushi-repeat-containing protein0.475
Ptgs2prostaglandin-endoperoxide synthase 20.471
Tgfb1transforming growth factor, beta 10.452
Wisp1WNT1 inducible signaling pathway protein 10.451
Pdcd1programmed cell death 10.431
Socs3suppressor of cytokine signaling 30.430
Ltblymphotoxin B0.421
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.408
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.394
Irg1immunoresponsive gene 10.389
Csf2colony stimulating factor 2 (granulocyte-macrophage)0.387
Ighimmunoglobulin heavy chain complex0.387
Fbn2fibrillin 20.386
Lmnalamin A0.386
CblCasitas B-lineage lymphoma0.383
Tgfb2transforming growth factor, beta 20.373
Bgnbiglycan0.363
Lrp1low density lipoprotein receptor-related protein 10.363
Egfrepidermal growth factor receptor0.362
Col4a3collagen, type IV, alpha 30.357
Socs2suppressor of cytokine signaling 20.355
Ccl2chemokine (C-C motif) ligand 20.349
Kdrkinase insert domain protein receptor0.337
Col4a6collagen, type IV, alpha 60.336
Cd19CD19 antigen0.327
Creb3l1cAMP responsive element binding protein 3-like 10.326
Nrg1neuregulin 10.323
Lama5laminin, alpha 50.312
Lama4laminin, alpha 40.310
Nf1neurofibromatosis 10.303
Ctskcathepsin K0.301
Bcl2B-cell leukemia/lymphoma 20.301
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.298
Loxl1lysyl oxidase-like 10.297
Ccr5chemokine (C-C motif) receptor 50.283
Tlr4toll-like receptor 40.275
Runx2runt related transcription factor 20.274
Igf1insulin-like growth factor 10.270
Ceacam16carcinoembryonic antigen-related cell adhesion molecule 160.269
Ezh2enhancer of zeste homolog 2 (Drosophila)0.266
Lyz2lysozyme 20.262
Itga1integrin alpha 10.257
Tnctenascin C0.251
Pthlhparathyroid hormone-like peptide0.242
Camk2bcalcium/calmodulin-dependent protein kinase II, beta0.239
Fkbp10FK506 binding protein 100.235
Nos2nitric oxide synthase 2, inducible0.234
Ptgfrnprostaglandin F2 receptor negative regulator0.230
Pdgfaplatelet derived growth factor, alpha0.225
Hspg2perlecan (heparan sulfate proteoglycan 2)0.224
MrgprfMAS-related GPR, member F0.221
Wt1Wilms tumor 1 homolog0.219
BaxBCL2-associated X protein0.217
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
LanALaminin A0.375
htlheartless0.267
aopanterior open0.162
Cg25CCollagen type IV0.074
exexpanded0.057
PpnPapilin0.056
vkgviking0.056
LanB2Laminin B20.052
Ras85DRas oncogene at 85D0.047
pntpointed0.047
GltGlutactin0.043
RagACG11968 gene product from transcript CG11968-RA0.033
Atg6Autophagy-specific gene 60.023
shnschnurri0.023
srpserpent0.022
CG5110CG5110 gene product from transcript CG5110-RA0.019
CG9067CG9067 gene product from transcript CG9067-RA0.018
CG12384CG12384 gene product from transcript CG12384-RA0.017
ifinflated0.016
shgshotgun0.016
Su(H)Suppressor of Hairless0.013
ushu-shaped0.013
konkon-tiki0.013
CG8372CG8372 gene product from transcript CG8372-RA0.013
18w18 wheeler0.012
drddrop dead0.012
Vrp1Verprolin 10.012
Bet5CG1359 gene product from transcript CG1359-RA0.011
Oatp74DOrganic anion transporting polypeptide 74D0.011
CG15012CG15012 gene product from transcript CG15012-RB0.011
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
RRAGCRas-related GTP binding C0.979
LAMTOR1late endosomal/lysosomal adaptor, MAPK and MTOR activator 10.798
COL4A1collagen, type IV, alpha 10.763
COL1A1collagen, type I, alpha 10.755
LAMTOR2late endosomal/lysosomal adaptor, MAPK and MTOR activator 20.745
UBE2Bubiquitin-conjugating enzyme E2B (RAD6 homolog)0.723
UBR1ubiquitin protein ligase E3 component n-recognin 10.708
TOB1transducer of ERBB2, 10.660
UHRF1ubiquitin-like with PHD and ring finger domains 10.474
DLG4discs, large homolog 4 (Drosophila)0.286
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.220
COL5A1collagen, type V, alpha 10.209
COL4A2collagen, type IV, alpha 20.180
PDGFAplatelet-derived growth factor alpha polypeptide0.177
CCR5chemokine (C-C motif) receptor 50.160
C7orf59chromosome 7 open reading frame 590.158
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.132
SPARCsecreted protein, acidic, cysteine-rich (osteonectin)0.130
MTORmechanistic target of rapamycin (serine/threonine kinase)0.116
HBXIPhepatitis B virus x interacting protein0.113
CTNND1catenin (cadherin-associated protein), delta 10.107
LAMTOR3late endosomal/lysosomal adaptor, MAPK and MTOR activator 30.102
COL1A2collagen, type I, alpha 20.101
FBN1fibrillin 10.094
COL3A1collagen, type III, alpha 10.083
TFRCtransferrin receptor (p90, CD71)0.079
DNMT1DNA (cytosine-5-)-methyltransferase 10.072
COL6A2collagen, type VI, alpha 20.067
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.057
CTBP1C-terminal binding protein 10.042
BCL2B-cell CLL/lymphoma 20.042
UBE2Aubiquitin-conjugating enzyme E2A (RAD6 homolog)0.035
COL18A1collagen, type XVIII, alpha 10.033
COL6A3collagen, type VI, alpha 30.032
COMMD1copper metabolism (Murr1) domain containing 10.032
NID1nidogen 10.031
DNAJB11DnaJ (Hsp40) homolog, subfamily B, member 110.031
EIF4EBP1eukaryotic translation initiation factor 4E binding protein 10.030
FADDFas (TNFRSF6)-associated via death domain0.030
CAMK2Acalcium/calmodulin-dependent protein kinase II alpha0.028
COL6A1collagen, type VI, alpha 10.027
DAXXdeath-domain associated protein0.026
POSTNperiostin, osteoblast specific factor0.025
DNMT3BDNA (cytosine-5-)-methyltransferase 3 beta0.022
JAK2Janus kinase 20.022
PXDNperoxidasin homolog (Drosophila)0.020
KCNA4potassium voltage-gated channel, shaker-related subfamily, member 40.020
GADD45Agrowth arrest and DNA-damage-inducible, alpha0.019
BGNbiglycan0.019
NID2nidogen 2 (osteonidogen)0.018
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.017
TCF4transcription factor 40.016
RRAGDRas-related GTP binding D0.016
TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha)0.016
CAPNS1calpain, small subunit 10.015
THBS2thrombospondin 20.015
COL5A2collagen, type V, alpha 20.015
CPEB3cytoplasmic polyadenylation element binding protein 30.015
CDH11cadherin 11, type 2, OB-cadherin (osteoblast)0.015
CASP10caspase 10, apoptosis-related cysteine peptidase0.015
KCNA1potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)0.015
TIMP2TIMP metallopeptidase inhibitor 20.014
DLGAP1discs, large (Drosophila) homolog-associated protein 10.014
PCOLCEprocollagen C-endopeptidase enhancer0.013
AKT1S1AKT1 substrate 1 (proline-rich)0.013
THBS1thrombospondin 10.013
LAMB1laminin, beta 10.013
COL4A5collagen, type IV, alpha 50.012
COL16A1collagen, type XVI, alpha 10.012
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.012
LAMA4laminin, alpha 40.012
LOXlysyl oxidase0.011
CASP8caspase 8, apoptosis-related cysteine peptidase0.011
THY1Thy-1 cell surface antigen0.011
MAGI3membrane associated guanylate kinase, WW and PDZ domain containing 30.011
MMP14matrix metallopeptidase 14 (membrane-inserted)0.011
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.011
UBR3ubiquitin protein ligase E3 component n-recognin 3 (putative)0.011
COL11A1collagen, type XI, alpha 10.011
LAMC1laminin, gamma 1 (formerly LAMB2)0.010
TGFB1transforming growth factor, beta 10.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
MRT4Mrt4p0.017
ARX1Arx1p0.015
UBI4Ubi4p0.014
RPA49Rpa49p0.014
GIS2Gis2p0.013
RPF2Rpf2p0.012
PUF6Puf6p0.011
UTP15Utp15p0.010
FEN1Fen1p0.010
LSG1Lsg1p0.010