The network for 'embryonic organ morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

embryonic organ morphogenesis

Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.

NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog1.000
Fgfr2fibroblast growth factor receptor 21.000
Gli3GLI-Kruppel family member GLI31.000
Foxc1forkhead box C11.000
Pax3paired box gene 31.000
Pitx2paired-like homeodomain transcription factor 21.000
Otx2orthodenticle homolog 2 (Drosophila)1.000
Eya1eyes absent 1 homolog (Drosophila)1.000
Bmp4bone morphogenetic protein 41.000
Tcfap2atranscription factor AP-2, alpha1.000
Tgfb2transforming growth factor, beta 21.000
Dlx5distal-less homeobox 51.000
Pax2paired box gene 21.000
Foxc2forkhead box C21.000
Tbx1T-box 11.000
Fgfr1fibroblast growth factor receptor 11.000
Vangl2vang-like 2 (van gogh, Drosophila)1.000
Fgf8fibroblast growth factor 81.000
Hand2heart and neural crest derivatives expressed transcript 21.000
Foxg1forkhead box G11.000
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)1.000
Chrdchordin1.000
Gli2GLI-Kruppel family member GLI21.000
Msx1homeobox, msh-like 11.000
Rargretinoic acid receptor, gamma1.000
Ctnnb1catenin (cadherin associated protein), beta 11.000
Chd7chromodomain helicase DNA binding protein 71.000
Msx2homeobox, msh-like 21.000
Hoxa1homeobox A11.000
Tgfbr2transforming growth factor, beta receptor II1.000
Fgf10fibroblast growth factor 101.000
Six1sine oculis-related homeobox 1 homolog (Drosophila)1.000
Pax6paired box gene 61.000
Bmp7bone morphogenetic protein 71.000
Hand1heart and neural crest derivatives expressed transcript 11.000
Pax8paired box gene 81.000
Gbx2gastrulation brain homeobox 21.000
Efnb2ephrin B21.000
Rarbretinoic acid receptor, beta1.000
Notch1Notch gene homolog 1 (Drosophila)1.000
Prrx1paired related homeobox 11.000
Vegfavascular endothelial growth factor A1.000
Sox2SRY-box containing gene 21.000
Ptenphosphatase and tensin homolog1.000
Ror2receptor tyrosine kinase-like orphan receptor 21.000
Tbx3T-box 31.000
Jag1jagged 11.000
Smosmoothened homolog (Drosophila)1.000
Nognoggin1.000
Gscgoosecoid homeobox1.000
Lef1lymphoid enhancer binding factor 10.999
Nodalnodal0.999
Acvr1activin A receptor, type 10.999
Isl1ISL1 transcription factor, LIM/homeodomain0.999
Psen1presenilin 10.999
Pax9paired box gene 90.999
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.999
Lhx3LIM homeobox protein 30.999
Zic3zinc finger protein of the cerebellum 30.998
Cdh23cadherin 23 (otocadherin)0.998
Hes1hairy and enhancer of split 1 (Drosophila)0.998
Meox2mesenchyme homeobox 20.998
Pbx1pre B-cell leukemia transcription factor 10.997
Prrx2paired related homeobox 20.997
Gata3GATA binding protein 30.997
Fgf3fibroblast growth factor 30.997
Rnf2ring finger protein 20.997
Ece1endothelin converting enzyme 10.997
Sall4sal-like 4 (Drosophila)0.996
Wt1Wilms tumor 1 homolog0.996
Lmx1aLIM homeobox transcription factor 1 alpha0.996
Hoxa3homeobox A30.995
Pax1paired box gene 10.995
Rararetinoic acid receptor, alpha0.995
Ednraendothelin receptor type A0.995
Hoxd13homeobox D130.995
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.995
Emx1empty spiracles homolog 1 (Drosophila)0.995
Runx2runt related transcription factor 20.995
Lhx1LIM homeobox protein 10.994
Wnt3awingless-related MMTV integration site 3A0.993
Hmx3H6 homeobox 30.993
Six4sine oculis-related homeobox 4 homolog (Drosophila)0.993
Zeb1zinc finger E-box binding homeobox 10.993
Pthlhparathyroid hormone-like peptide0.992
Lrp6low density lipoprotein receptor-related protein 60.991
Emx2empty spiracles homolog 2 (Drosophila)0.991
Hoxd3homeobox D30.991
Itgb1integrin beta 1 (fibronectin receptor beta)0.990
Hoxa5homeobox A50.989
Mks1Meckel syndrome, type 10.989
Col1a1collagen, type I, alpha 10.989
Lmx1bLIM homeobox transcription factor 1 beta0.989
Ptk7PTK7 protein tyrosine kinase 70.987
Gata6GATA binding protein 60.987
Pitx1paired-like homeodomain transcription factor 10.986
Ephb2Eph receptor B20.986
Twist2twist homolog 2 (Drosophila)0.986
Mesp1mesoderm posterior 10.986
Gata4GATA binding protein 40.986
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
hlh-1Protein HLH-10.022
unc-73Protein UNC-730.019
egl-18Protein EGL-180.016
ceh-32Protein CEH-320.016
pha-4Protein PHA-40.012
bar-1Protein BAR-10.011
nhr-25Protein NHR-250.011
egl-46Protein EGL-460.011
che-13Protein CHE-130.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
sox9aSRY-box containing gene 9a1.000
tbx1T-box 11.000
foxi1forkhead box I11.000
gata3GATA-binding protein 31.000
chdchordin0.999
edn1endothelin 10.997
eya1eyes absent homolog 10.996
col2a1acollagen type II, alpha-1a0.995
dlx2adistal-less homeobox gene 2a0.995
bmp2abone morphogenetic protein 2a0.991
barx1BarH-like homeobox 10.990
gli2aGLI-Kruppel family member GLI2a0.989
hand2heart and neural crest derivatives expressed transcript 20.988
irx1airoquois homeobox protein 1, a0.987
wnt11rwingless-type MMTV integration site family, member 11, related0.987
hnf1baHNF1 homeobox Ba0.986
tp53tumor protein p530.985
shhasonic hedgehog a0.984
hoxb5bhomeo box B5b0.983
wu:fv91b12wu:fv91b120.978
twist1atwist1a0.978
pax2apaired box gene 2a0.977
plcb3phospholipase C, beta 3 (phosphatidylinositol-specific)0.977
dlx4bdistal-less homeobox gene 4b0.976
crabp2acellular retinoic acid binding protein 2, a0.975
myod1myogenic differentiation 10.974
twist3twist30.974
mibmind bomb0.973
jag1bjagged 1b0.972
foxa2forkhead box A20.971
wnt11wingless-type MMTV integration site family, member 110.970
prdm1aPR domain containing 1a, with ZNF domain0.965
chsy1chondroitin sulfate synthase 10.964
foxd3forkhead box D30.954
cdh2cadherin 2, neuronal0.945
gata4GATA-binding protein 40.943
dlx3bdistal-less homeobox gene 3b0.941
pitx3paired-like homeodomain transcription factor 30.941
gpr126G protein-coupled receptor 1260.941
dachadachshund a0.937
pax8paired box gene 80.936
dlx4adistal-less homeobox gene 4a0.935
aldh1a2aldehyde dehydrogenase 1 family, member A20.931
mef2cbmyocyte enhancer factor 2cb0.931
smad5MAD homolog 5 (Drosophila)0.930
ndr2nodal-related 20.930
egr2bearly growth response 2b0.928
six4bsine oculis homeobox homolog 4b0.922
hoxb2ahomeo box B2a0.922
tbx5aT-box 5a0.921
runx2brunt-related transcription factor 2b0.919
disp1dispatched homolog 1 (Drosophila)0.918
rereaarginine-glutamic acid dipeptide (RE) repeats a0.918
cyp26b1cytochrome P450, family 26, subfamily b, polypeptide 10.918
pcdh10bprotocadherin 10b0.916
sox32SRY-box containing gene 320.915
her6hairy-related 60.914
hmx4H6 family homeobox 40.911
neurodneurogenic differentiation0.908
lamb1alaminin, beta 1a0.907
fzd8afrizzled homolog 8a0.906
lft2lefty20.905
wt1awilms tumor 1a0.904
hoxb3ahomeo box B3a0.898
pkd2polycystic kidney disease 20.897
snai1bsnail homolog 1b (Drosophila)0.895
fgf8afibroblast growth factor 8 a0.894
hoxa3ahomeo box A3a0.894
hey1hairy/enhancer-of-split related with YRPW motif 10.891
zeb2azinc finger E-box binding homeobox 2a0.891
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.886
LOC100536439parathyroid hormone-related protein-like0.878
rx3retinal homeobox gene 30.876
fgf3fibroblast growth factor 30.875
twist1btwist1b0.874
runx2arunt-related transcription factor 2a0.873
hoxa2bhomeo box A2b0.872
sp5lSp5 transcription factor-like0.872
myh6myosin, heavy polypeptide 6, cardiac muscle, alpha0.871
fras1Fraser syndrome 10.870
tfap2atranscription factor AP-2 alpha0.865
trpm7transient receptor potential cation channel, subfamily M, member 70.865
hapln1ahyaluronan and proteoglycan link protein 1a0.863
smad9MAD homolog 9 (Drosophila)0.855
dlcdeltaC0.855
dccdeleted in colorectal carcinoma0.853
flhfloating head0.852
zic1zic family member 1 (odd-paired homolog, Drosophila)0.851
fgfr4fibroblast growth factor receptor 40.849
fgf10afibroblast growth factor 10a0.844
otx1aorthodenticle homolog 1a0.832
loxl3blysyl oxidase-like 3b0.831
hoxd4ahomeo box D4a0.828
fstafollistatin a0.824
rx2retinal homeobox gene 20.823
epb4.1l4erythrocyte protein band 4.1-like 40.821
foxc1aforkhead box C1a0.818
msxemuscle segment homeobox E0.818
sec24dSEC24 family, member D (S. cerevisiae)0.818
nkx2.7NK2 transcription factor related 70.816
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
cicubitus interruptus0.745
wgwingless0.625
emcextra macrochaetae0.564
Fas2Fasciclin 20.416
tkvthickveins0.362
sdscalloped0.287
dppdecapentaplegic0.261
enengrailed0.255
E(spl)Enhancer of split0.220
fngfringe0.181
NNotch0.174
HLHmbetaE(spl) region transcript mbeta0.173
HLHmdeltaE(spl) region transcript mdelta0.148
dshdishevelled0.143
fz2frizzled 20.136
sogshort gastrulation0.126
apapterous0.106
nkdnaked cuticle0.105
zfh1Zn finger homeodomain 10.104
lzlozenge0.101
SerSerrate0.097
m4E(spl) region transcript m40.086
grogroucho0.074
shishibire0.071
LanB2Laminin B20.070
slp1sloppy paired 10.070
EgfrEpidermal growth factor receptor0.067
MadMothers against dpp0.066
araaraucan0.064
LanALaminin A0.059
panpangolin0.058
mewmultiple edematous wings0.056
Sra-1specifically Rac1-associated protein 10.053
bab2CG9102 gene product from transcript CG9102-RA0.051
G-oalpha47AG protein oalpha 47A0.051
dsdachsous0.050
eveeven skipped0.047
dallydivision abnormally delayed0.045
slouslouch0.045
Rho1CG8416 gene product from transcript CG8416-RB0.043
vvlventral veins lacking0.043
shnschnurri0.043
Wnt4Wnt oncogene analog 40.040
ttvtout-velu0.040
HLHm3E(spl) region transcript m30.039
linlines0.037
TolloCG6890 gene product from transcript CG6890-RA0.036
eyaeyes absent0.036
hipkhomeodomain interacting protein kinase0.035
ococelliless0.035
HLHm5E(spl) region transcript m50.034
spensplit ends0.034
LanB1CG7123 gene product from transcript CG7123-RA0.033
arrarrow0.033
acachaete0.032
Stat92ESignal-transducer and activator of transcription protein at 92E0.031
Cdc42CG12530 gene product from transcript CG12530-RA0.031
crbcrumbs0.031
midmidline0.029
sosine oculis0.029
fzfrizzled0.029
ushu-shaped0.028
coracoracle0.028
hthhomothorax0.027
TomTwin of m40.026
atoatonal0.025
AntpAntennapedia0.025
sbbscribbler0.023
tshteashirt0.023
HLHm7E(spl) region transcript m70.023
wbwing blister0.023
lealeak0.022
tintinman0.021
sggshaggy0.021
stumpsCG31317 gene product from transcript CG31317-RC0.021
foxoforkhead box, sub-group O0.020
PoxnPox neuro0.020
argosCG4531 gene product from transcript CG4531-RA0.019
exexpanded0.018
roboroundabout0.017
nmonemo0.017
armarmadillo0.017
kirrekin of irre0.017
snssticks and stones0.017
CtBPC-terminal Binding Protein0.016
cindrCIN85 and CD2AP orthologue0.016
hbshibris0.016
18w18 wheeler0.016
opaodd paired0.015
Klp64DKinesin-like protein at 64D0.015
htlheartless0.015
m2E(spl) region transcript m20.015
nubnubbin0.015
nejnejire0.014
SoxNSoxNeuro0.014
CapsCalcium activated protein for secretion0.014
eygeyegone0.014
mbcmyoblast city0.013
prosprospero0.013
toytwin of eyeless0.013
Loading network...
Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.992
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.984
SIN3ASIN3 homolog A, transcription regulator (yeast)0.971
SP1Sp1 transcription factor0.970
RBBP4retinoblastoma binding protein 40.951
EP300E1A binding protein p3000.937
CREBBPCREB binding protein0.933
HDAC1histone deacetylase 10.933
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.911
SMAD4SMAD family member 40.817
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.790
HOXB5homeobox B50.753
SMAD2SMAD family member 20.750
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.742
NCOR1nuclear receptor corepressor 10.725
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.710
FGFR1fibroblast growth factor receptor 10.678
TAL1T-cell acute lymphocytic leukemia 10.640
COL1A1collagen, type I, alpha 10.621
COL3A1collagen, type III, alpha 10.606
RUNX1runt-related transcription factor 10.590
JAG1jagged 10.538
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.522
MYCv-myc myelocytomatosis viral oncogene homolog (avian)0.513
SMAD3SMAD family member 30.495
CSNK2A1casein kinase 2, alpha 1 polypeptide0.494
TCF4transcription factor 40.473
RB1retinoblastoma 10.470
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.452
NR2E3nuclear receptor subfamily 2, group E, member 30.368
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.336
DHX30DEAH (Asp-Glu-Ala-His) box polypeptide 300.319
LAMB1laminin, beta 10.299
SMAD7SMAD family member 70.292
HOXA10homeobox A100.286
ATF2activating transcription factor 20.283
BMP2bone morphogenetic protein 20.259
COL1A2collagen, type I, alpha 20.250
GSK3Bglycogen synthase kinase 3 beta0.246
FGF1fibroblast growth factor 1 (acidic)0.236
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.218
TGFB1transforming growth factor, beta 10.216
HDAC4histone deacetylase 40.212
SMAD1SMAD family member 10.212
GATA4GATA binding protein 40.209
FSTL1follistatin-like 10.207
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.206
BMI1BMI1 polycomb ring finger oncogene0.204
YAP1Yes-associated protein 10.199
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.195
TCF12transcription factor 120.189
HOXA5homeobox A50.188
SIRT1sirtuin 10.184
YY1YY1 transcription factor0.183
HOXD9homeobox D90.181
TRIP6thyroid hormone receptor interactor 60.176
BMPR1Abone morphogenetic protein receptor, type IA0.175
JUNjun proto-oncogene0.173
NOTCH3notch 30.172
HOXC8homeobox C80.170
GABPAGA binding protein transcription factor, alpha subunit 60kDa0.169
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.166
USP7ubiquitin specific peptidase 7 (herpes virus-associated)0.165
PTPN11protein tyrosine phosphatase, non-receptor type 110.161
CSNK1Ecasein kinase 1, epsilon0.154
BMP1bone morphogenetic protein 10.150
BMP4bone morphogenetic protein 40.147
FOXA2forkhead box A20.146
APCadenomatous polyposis coli0.144
ZFXzinc finger protein, X-linked0.144
TP53tumor protein p530.140
MYOD1myogenic differentiation 10.140
MMP14matrix metallopeptidase 14 (membrane-inserted)0.133
HOXB6homeobox B60.133
HOXA11homeobox A110.132
HOXB3homeobox B30.131
BCORBCL6 corepressor0.131
SNX5sorting nexin 50.129
VEGFAvascular endothelial growth factor A0.127
ZFYVE9zinc finger, FYVE domain containing 90.125
HNF4Ahepatocyte nuclear factor 4, alpha0.125
HOXB9homeobox B90.123
HMGA2high mobility group AT-hook 20.120
RBBP7retinoblastoma binding protein 70.120
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.114
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.114
DYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A0.109
MDM2Mdm2 p53 binding protein homolog (mouse)0.109
TJP1tight junction protein 1 (zona occludens 1)0.108
COL5A1collagen, type V, alpha 10.105
HOXD13homeobox D130.105
LRP6low density lipoprotein receptor-related protein 60.102
BMP7bone morphogenetic protein 70.101
COL4A1collagen, type IV, alpha 10.098
SOX11SRY (sex determining region Y)-box 110.097
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 20.096
NR4A1nuclear receptor subfamily 4, group A, member 10.091
CITED2Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 20.091
TP73tumor protein p730.090
HOXA9homeobox A90.086
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Syt4synaptotagmin IV0.097
Hoxb7homeo box B70.082
Fgfr1Fibroblast growth factor receptor 10.081
Btg2BTG family, member 20.056
Hoxc4homeo box C40.056
Erbb4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.053
Serpine2serine (or cysteine) peptidase inhibitor, clade E, member 20.046
Atp1b1ATPase, Na+/K+ transporting, beta 1 polypeptide0.046
Sirpasignal-regulatory protein alpha0.045
Igfbp5insulin-like growth factor binding protein 50.045
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.045
Dusp6dual specificity phosphatase 60.042
Bgnbiglycan0.040
FosFBJ osteosarcoma oncogene0.034
Nr4a1nuclear receptor subfamily 4, group A, member 10.031
Nedd4neural precursor cell expressed, developmentally down-regulated 40.028
Dlg4discs, large homolog 4 (Drosophila)0.027
Dab2disabled homolog 2 (Drosophila)0.025
Dmddystrophin0.025
Twist2twist homolog 2 (Drosophila)0.025
Dchs1dachsous 1 (Drosophila)0.024
Runx1runt-related transcription factor 10.022
Sdc3syndecan 30.020
Tcfe2atranscription factor E2a0.020
Fn1fibronectin 10.020
Egr2early growth response 20.019
Nfibnuclear factor I/B0.019
Igf1insulin-like growth factor 10.019
Jak1Janus kinase 10.019
Nfianuclear factor I/A0.018
Cald1caldesmon 10.018
Add3adducin 3 (gamma)0.018
Gdf11growth differentiation factor 110.016
Col3a1collagen, type III, alpha 10.016
Fgfr2fibroblast growth factor receptor 20.016
Galr2galanin receptor 20.015
Cyr61cysteine-rich, angiogenic inducer, 610.015
Atp2b1ATPase, Ca++ transporting, plasma membrane 10.015
Lamc1laminin, gamma 10.015
Gria4glutamate receptor, ionotrophic, AMPA 40.015
Serpinh1serine (or cysteine) peptidase inhibitor, clade H, member 10.015
KlKlotho0.014
Tead1TEA domain family member 10.014
Bmp3bone morphogenetic protein 30.014
Lig3ligase III, DNA, ATP-dependent0.014
RestRE1-silencing transcription factor0.014
Bmp7bone morphogenetic protein 70.014
Bmp6bone morphogenetic protein 60.014
Hand2heart and neural crest derivatives expressed 20.014
Pnliprp1pancreatic lipase-related protein 10.013
Sema3asema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A0.013
Kcnq1potassium voltage-gated channel, KQT-like subfamily, member 10.013
Mybpc2myosin binding protein C, fast-type0.013
Gna12guanine nucleotide binding protein (G protein) alpha 120.013
Nr4a2nuclear receptor subfamily 4, group A, member 20.012
Tgfbr2transforming growth factor, beta receptor II0.012
Ddr2discoidin domain receptor tyrosine kinase 20.012
Sox17SRY (sex determining region Y)-box 170.012
Pkiaprotein kinase (cAMP-dependent, catalytic) inhibitor alpha0.011
Tgfb2transforming growth factor, beta 20.011
RragBRas-related GTP binding B0.011
RGD1305627hypothetical LOC3144670.011
Hspd1heat shock protein 1 (chaperonin)0.011
Nek9NIMA (never in mitosis gene a)- related kinase 90.011
Grm5glutamate receptor, metabotropic 50.011
Efna5ephrin A50.010
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.010
Marcksmyristoylated alanine rich protein kinase C substrate0.010
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism