The network for 'chromatin disassembly' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

chromatin disassembly

The controlled breakdown of chromatin from a higher order structure into its simpler subcomponents, DNA, histones, other proteins, and sometimes RNA.

NameDescriptionProbabilityFunc Analog Organism
Smarcc1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 11.000
Smarca4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 41.000
Arid1aAT rich interactive domain 1A (SWI-like)1.000
Arid1bAT rich interactive domain 1B (SWI-like)1.000
Smarca2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 21.000
Smarcc2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 21.000
Smarcb1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 11.000
Hist1h1chistone cluster 1, H1c0.996
Smarcd1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 10.990
Smarcd3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 30.987
Uhrf1ubiquitin-like, containing PHD and RING finger domains, 10.974
Hist1h2brhistone cluster 1 H2br0.965
Prmt5protein arginine N-methyltransferase 50.957
Smarce1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 10.911
Hist1h2bmhistone cluster 1, H2bm0.801
Hist1h2bphistone cluster 1, H2bp0.773
Numa1nuclear mitotic apparatus protein 10.630
Hist1h2bbhistone cluster 1, H2bb0.455
Hist2h3c1histone cluster 2, H3c10.410
Sin3atranscriptional regulator, SIN3A (yeast)0.408
Tcfcp2l1transcription factor CP2-like 10.304
Whsc1Wolf-Hirschhorn syndrome candidate 1 (human)0.293
Hist1h2bjhistone cluster 1, H2bj0.279
Hist1h2bqhistone cluster 1, H2bq0.253
L3mbtl2l(3)mbt-like 2 (Drosophila)0.252
Chd4chromodomain helicase DNA binding protein 40.241
Hist1h2bahistone cluster 1, H2ba0.237
Brd3bromodomain containing 30.183
Trp53transformation related protein 530.162
Mybbp1aMYB binding protein (P160) 1a0.150
Ss18l1synovial sarcoma translocation gene on chromosome 18-like 10.149
Pbrm1polybromo 10.147
Hist1h3ghistone cluster 1, H3g0.145
Hist1h2bghistone cluster 1, H2bg0.129
E2f1E2F transcription factor 10.128
Trim28tripartite motif-containing 280.126
Kdm4alysine (K)-specific demethylase 4A0.124
Polr2apolymerase (RNA) II (DNA directed) polypeptide A0.106
Ubap2ubiquitin-associated protein 20.105
Dnmt1DNA methyltransferase (cytosine-5) 10.094
Brd4bromodomain containing 40.092
Rnf44ring finger protein 440.091
Hist1h1bhistone cluster 1, H1b0.090
Hdac1histone deacetylase 10.089
E2f4E2F transcription factor 40.080
Prpf8pre-mRNA processing factor 80.071
Cdca8cell division cycle associated 80.068
Spc24SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.066
Hist1h2bhhistone cluster 1, H2bh0.063
Hist2h2aa2histone cluster 2, H2aa20.061
Hist2h2behistone cluster 2, H2be0.060
Hist1h2akhistone cluster 1, H2ak0.059
Cherpcalcium homeostasis endoplasmic reticulum protein0.058
Hist1h2bkhistone cluster 1, H2bk0.058
Smad1MAD homolog 1 (Drosophila)0.057
Chaf1achromatin assembly factor 1, subunit A (p150)0.055
Rb1retinoblastoma 10.053
H2afyH2A histone family, member Y0.053
Hist1h1ahistone cluster 1, H1a0.053
Creb1cAMP responsive element binding protein 10.051
Spa17sperm autoantigenic protein 170.050
Hist4h4histone cluster 4, H40.049
Hist1h3chistone cluster 1, H3c0.049
Hist1h2abhistone cluster 1, H2ab0.047
Hist1h2aahistone cluster 1, H2aa0.044
Nup188nucleoporin 1880.041
Patz1POZ (BTB) and AT hook containing zinc finger 10.040
Hist1h2aohistone cluster 1, H2ao0.038
Hist1h1dhistone cluster 1, H1d0.036
Rnf38ring finger protein 380.035
Hist2h2abhistone cluster 2, H2ab0.035
Ncapd2non-SMC condensin I complex, subunit D20.034
Hist1h4mhistone cluster 1, H4m0.032
H2afvH2A histone family, member V0.031
Add1adducin 1 (alpha)0.030
Hist1h4fhistone cluster 1, H4f0.030
Kdm6bKDM1 lysine (K)-specific demethylase 6B0.029
Msl1male-specific lethal 1 homolog (Drosophila)0.029
Ep300E1A binding protein p3000.029
Gltscr1glioma tumor suppressor candidate region gene 10.028
C2cd3C2 calcium-dependent domain containing 30.028
Sall4sal-like 4 (Drosophila)0.028
Nphp1nephronophthisis 1 (juvenile) homolog (human)0.027
Eif4g3eukaryotic translation initiation factor 4 gamma, 30.027
Adnpactivity-dependent neuroprotective protein0.026
Hist1h3ahistone cluster 1, H3a0.025
H2afxH2A histone family, member X0.023
Ssbp3single-stranded DNA binding protein 30.023
Asxl1additional sex combs like 1 (Drosophila)0.022
Ints9integrator complex subunit 90.021
Hist1h2behistone cluster 1, H2be0.021
Atp1b2ATPase, Na+/K+ transporting, beta 2 polypeptide0.021
Nononon-POU-domain-containing, octamer binding protein0.020
Pou2f1POU domain, class 2, transcription factor 10.020
Ints7integrator complex subunit 70.020
Hist1h4dhistone cluster 1, H4d0.020
Sf3a1splicing factor 3a, subunit 10.020
Eftud2elongation factor Tu GTP binding domain containing 20.019
U2af2U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 20.019
Atxn2ataxin 20.019
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
ARID1AAT rich interactive domain 1A (SWI-like)0.999
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.999
HIST1H3Dhistone cluster 1, H3d0.999
HIST1H2BGhistone cluster 1, H2bg0.996
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 10.990
HIST1H2BDhistone cluster 1, H2bd0.988
HIST1H1Chistone cluster 1, H1c0.980
HIST2H2AA4histone cluster 2, H2aa40.974
HIST1H2AEhistone cluster 1, H2ae0.960
HIST2H2BEhistone cluster 2, H2be0.956
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.937
HIST1H2BFhistone cluster 1, H2bf0.911
ARID1BAT rich interactive domain 1B (SWI1-like)0.896
HIST1H2BChistone cluster 1, H2bc0.861
HIST1H2BIhistone cluster 1, H2bi0.769
HIST1H2BEhistone cluster 1, H2be0.764
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 20.749
HIST1H2AJhistone cluster 1, H2aj0.713
PBRM1polybromo 10.705
ARID2AT rich interactive domain 2 (ARID, RFX-like)0.660
HIST1H2AIhistone cluster 1, H2ai0.581
HIST1H2AChistone cluster 1, H2ac0.498
SMARCB1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 10.403
HIST1H2BHhistone cluster 1, H2bh0.394
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 10.338
HIST1H2BKhistone cluster 1, H2bk0.253
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 20.251
HIST1H4Hhistone cluster 1, H4h0.225
HIST1H3Hhistone cluster 1, H3h0.213
HIST1H2AMhistone cluster 1, H2am0.194
MMS22LMMS22-like, DNA repair protein0.181
HIST1H2BMhistone cluster 1, H2bm0.083
HIST1H3Ahistone cluster 1, H3a0.078
TONSLtonsoku-like, DNA repair protein0.071
HIST1H2BJhistone cluster 1, H2bj0.067
CARM1coactivator-associated arginine methyltransferase 10.063
HIST1H2AGhistone cluster 1, H2ag0.055
HIST1H2ALhistone cluster 1, H2al0.047
FANCAFanconi anemia, complementation group A0.042
HIST1H4Dhistone cluster 1, H4d0.038
HIST1H3Ghistone cluster 1, H3g0.036
HIST1H2BBhistone cluster 1, H2bb0.036
CDAN1congenital dyserythropoietic anemia, type I0.034
TLK1tousled-like kinase 10.032
HIST1H2ABhistone cluster 1, H2ab0.031
HIST1H2BOhistone cluster 1, H2bo0.030
CBX5chromobox homolog 50.029
HIST1H4Ehistone cluster 1, H4e0.022
BRD7bromodomain containing 70.020
HIST2H2AA3histone cluster 2, H2aa30.018
SIN3ASIN3 homolog A, transcription regulator (yeast)0.018
HIST1H4Bhistone cluster 1, H4b0.018
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.014
SMARCD2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 20.013
ARRB2arrestin, beta 20.012
HIST1H4Ahistone cluster 1, H4a0.011
HIST1H4Jhistone cluster 1, H4j0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Ubtfupstream binding transcription factor, RNA polymerase I0.052
Pdap1PDGFA associated protein 10.038
Dhx30DEAH (Asp-Glu-Ala-His) box polypeptide 300.036
Safbscaffold attachment factor B0.033
Usp5ubiquitin specific peptidase 5 (isopeptidase T)0.028
Fam195bfamily with sequence similarity 195, member B0.025
Chd4chromodomain helicase DNA binding protein 40.024
GeftRhoA/RAC/CDC42 exchange factor0.017
Sf3b2splicing factor 3b, subunit 20.017
Pcnxl3pecanex-like 3 (Drosophila)0.015
Atp1b2ATPase, Na+/K+ transporting, beta 2 polypeptide0.014
Trim28tripartite motif-containing 280.014
Acin1apoptotic chromatin condensation inducer 10.014
Akt1v-akt murine thymoma viral oncogene homolog 10.013
Hdlbphigh density lipoprotein binding protein0.013
Camta2calmodulin binding transcription activator 20.012
Rnf10ring finger protein 100.012
Psmd2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.012
RGD1308134similar to RIKEN cDNA 1110020A230.012
Snrpbsmall nuclear ribonucleoprotein polypeptides B and B10.012
Wsb2WD repeat and SOCS box-containing 20.012
Ptprsprotein tyrosine phosphatase, receptor type, S0.011
Actr1aARP1 actin-related protein 1 homolog A, centractin alpha (yeast)0.011
Parp1poly (ADP-ribose) polymerase 10.011
Ino80eINO80 complex subunit E0.011
Bap1BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
RSC8Rsc8p0.996
RSC4Rsc4p0.989
HHF1Hhf1p0.955
RSC2Rsc2p0.938
STH1Sth1p0.905
RSC3Rsc3p0.895
RSC9Rsc9p0.892
RSC6Rsc6p0.891
RSC58Rsc58p0.830
ARP7Arp7p0.729
NPL6Npl6p0.661
HHT1Hht1p0.641
RTT102Rtt102p0.612
ARP9Arp9p0.584
SFH1Sfh1p0.533
RSC1Rsc1p0.469
SWI1Swi1p0.368
HTL1Htl1p0.277
HHF2Hhf2p0.237
RSC30Rsc30p0.112
BDF1Bdf1p0.047
HHT2Hht2p0.041
NHP6ANhp6ap0.039
SPT10Spt10p0.037
EPL1Epl1p0.021
SNF12Snf12p0.020
PCL9Pcl9p0.020
EAF1Eaf1p0.019
BDF2Bdf2p0.017
SNF11Snf11p0.017
CRP1Crp1p0.016
SWI3Swi3p0.016
SRD1Srd1p0.015
SWC7Swc7p0.015
CUP1-1Cup1-1p0.015
SPL2Spl2p0.014
REB1Reb1p0.014
YLR264C-Ahypothetical protein0.014
YOL038C-Ahypothetical protein0.013
LEU2Leu2p0.013
PTI1Pti1p0.012
YLR162Whypothetical protein0.012
ARP10Arp10p0.012
MER1Mer1p0.012
YTA7Yta7p0.012
HXT3Hxt3p0.011
YPR157Whypothetical protein0.010
SWC3Swc3p0.010
YLR042Chypothetical protein0.010
ATP6Atp6p0.010
CHA1Cha1p0.010
IOC2Ioc2p0.010